STRINGSTRING
HEY2 HEY2 WWC1 WWC1 MAML1 MAML1 JAG1 JAG1 KAT2B KAT2B ENSGGOP00000019740 ENSGGOP00000019740 G3RT71_GORGO G3RT71_GORGO IKZF1 IKZF1 APH1A APH1A PSENEN PSENEN MAMLD1 MAMLD1 HES4 HES4 MIB1 MIB1 PBX1 PBX1 G3R524_GORGO G3R524_GORGO G3R439_GORGO G3R439_GORGO HEY1 HEY1 NOTCH1 NOTCH1 PBX3 PBX3 HES1 HES1 HEYL HEYL EP300 EP300 RPS27A RPS27A G3QXA1_GORGO G3QXA1_GORGO CREBBP CREBBP PBX4 PBX4 EGF EGF DLL1 DLL1 KAT2A KAT2A G3QQC0_GORGO G3QQC0_GORGO YBX1 YBX1 WWP2 WWP2 DLGAP5 DLGAP5 PSEN2 PSEN2 G3S2R7_GORGO G3S2R7_GORGO PBX2 PBX2 NOTCH3 NOTCH3 PSEN1 PSEN1 G3QGA0_GORGO G3QGA0_GORGO UBC UBC PLXND1 PLXND1 ENSGGOP00000049329 ENSGGOP00000049329 NCSTN NCSTN ENSGGOP00000045153 ENSGGOP00000045153 APH1B APH1B RBPJ RBPJ EGFR EGFR ENSGGOP00000038520 ENSGGOP00000038520 FABP7 FABP7 ENSGGOP00000030777 ENSGGOP00000030777 DLL4 DLL4 STAT1 STAT1 G3SEP4_GORGO G3SEP4_GORGO MAML2 MAML2 G3S8E4_GORGO G3S8E4_GORGO NEURL1 NEURL1 SNW1 SNW1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HEY2Orange domain-containing protein. (257 aa)
WWC1WW and C2 domain containing 1. (1119 aa)
MAML1Mastermind like transcriptional coactivator 1. (939 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
KAT2BHistone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (820 aa)
ENSGGOP00000019740annotation not available (156 aa)
G3RT71_GORGOCSD_1 domain-containing protein. (318 aa)
IKZF1IKAROS family zinc finger 1. (519 aa)
APH1AAph-1 homolog A, gamma-secretase subunit. (265 aa)
PSENENPresenilin enhancer, gamma-secretase subunit. (101 aa)
MAMLD1Mastermind like domain containing 1. (999 aa)
HES4Hes family bHLH transcription factor 4. (221 aa)
MIB1Mindbomb E3 ubiquitin protein ligase 1. (1006 aa)
PBX1PBX homeobox 1. (430 aa)
G3R524_GORGOADAM metallopeptidase domain 10. (705 aa)
G3R439_GORGOHes family bHLH transcription factor 5. (165 aa)
HEY1Hes related family bHLH transcription factor with YRPW motif 1. (308 aa)
NOTCH1Uncharacterized protein. (1606 aa)
PBX3Homeobox domain-containing protein. (450 aa)
HES1Hes family bHLH transcription factor 1. (280 aa)
HEYLHes related family bHLH transcription factor with YRPW motif like. (328 aa)
EP300E1A binding protein p300. (2416 aa)
RPS27AUbiquitin-like domain-containing protein. (156 aa)
G3QXA1_GORGODelta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1199 aa)
CREBBPCREB binding protein. (2436 aa)
PBX4PBX homeobox 4. (348 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1183 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (723 aa)
KAT2AHistone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (837 aa)
G3QQC0_GORGOUncharacterized protein. (315 aa)
YBX1Y-box binding protein 1. (324 aa)
WWP2E3 ubiquitin-protein ligase. (870 aa)
DLGAP5DLG associated protein 5. (846 aa)
PSEN2Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (481 aa)
G3S2R7_GORGOCSP domain-containing protein. (280 aa)
PBX2PBX homeobox 2. (403 aa)
NOTCH3Notch receptor 3. (2317 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (376 aa)
G3QGA0_GORGOPre T cell antigen receptor alpha. (296 aa)
UBCPolyubiquitin-C; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair [...] (315 aa)
PLXND1Plexin D1. (1925 aa)
ENSGGOP00000049329Uncharacterized protein. (425 aa)
NCSTNNicastrin. (721 aa)
ENSGGOP00000045153Mindbomb E3 ubiquitin protein ligase 2. (979 aa)
APH1BAph-1 homolog B, gamma-secretase subunit. (257 aa)
RBPJRecombination signal binding protein for immunoglobulin kappa J region. (488 aa)
EGFRReceptor protein-tyrosine kinase. (1205 aa)
ENSGGOP00000038520Ubiquitin-like domain-containing protein. (187 aa)
FABP7Fatty acid binding protein 7; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (166 aa)
ENSGGOP00000030777Transforming acidic coiled-coil containing protein 3. (832 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (685 aa)
STAT1Signal transducer and activator of transcription. (777 aa)
G3SEP4_GORGOUbiquitin-like domain-containing protein. (156 aa)
MAML2Mastermind like transcriptional coactivator 2. (1155 aa)
G3S8E4_GORGOCSP domain-containing protein. (314 aa)
NEURL1Neuralized E3 ubiquitin protein ligase 1. (574 aa)
SNW1SNW domain containing 1. (571 aa)
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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