(50 nodes) 7 transmembrane receptor (Secretin family) network (Gorilla gorilla)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	G3RRX8_GORGO	Adhesion G protein-coupled receptor L4; Belongs to the G-protein coupled receptor 2 family. (621 aa)
	PTH2R	Parathyroid hormone 2 receptor; Belongs to the G-protein coupled receptor 2 family. (550 aa)
	GIPR	Gastric inhibitory polypeptide receptor; Belongs to the G-protein coupled receptor 2 family. (466 aa)
	G3RIH3_GORGO	ADCYAP receptor type I; Belongs to the G-protein coupled receptor 2 family. (524 aa)
	GLP1R	Glucagon like peptide 1 receptor; Belongs to the G-protein coupled receptor 2 family. (463 aa)
	ADGRG5	Adhesion G protein-coupled receptor G5; Belongs to the G-protein coupled receptor 2 family. (530 aa)
	GPR143	G protein-coupled receptor 143. (404 aa)
	ADGRF4	Adhesion G protein-coupled receptor F4; Belongs to the G-protein coupled receptor 2 family. (752 aa)
	G3RBI2_GORGO	Adhesion G protein-coupled receptor E2; Belongs to the G-protein coupled receptor 2 family. (827 aa)
	GCGR	Glucagon receptor; Belongs to the G-protein coupled receptor 2 family. (480 aa)
	G3R6D2_GORGO	Adhesion G protein-coupled receptor F3; Belongs to the G-protein coupled receptor 2 family. (1077 aa)
	ADGRV1	Adhesion G protein-coupled receptor V1; Belongs to the G-protein coupled receptor 2 family. (6306 aa)
	ADGRG7	Adhesion G protein-coupled receptor G7; Belongs to the G-protein coupled receptor 2 family. (797 aa)
	G3R0T7_GORGO	Adhesion G protein-coupled receptor D2; Belongs to the G-protein coupled receptor 2 family. (952 aa)
	GLP2R	Glucagon like peptide 2 receptor; Belongs to the G-protein coupled receptor 2 family. (553 aa)
	ADGRG3	Adhesion G protein-coupled receptor G3; Belongs to the G-protein coupled receptor 2 family. (549 aa)
	ADGRG1	Adhesion G-protein coupled receptor G1; Receptor involved in cell adhesion and probably in cell-cell interactions. Mediates cell matrix adhesion in developing neurons and hematopoietic stem cells. Receptor for collagen III/COL3A1 in the developing brain and involved in regulation of cortical development, specifically in maintenance of the pial basement membrane integrity and in cortical lamination. Binding to the COL3A1 ligand inhibits neuronal migration and activates the RhoA pathway by coupling to GNA13 and possibly GNA12. Plays a role in the maintenance of hematopoietic stem cells a [...] (693 aa)
	ADGRF5	Adhesion G protein-coupled receptor F5; Belongs to the G-protein coupled receptor 2 family. (1346 aa)
	G3QXX7_GORGO	Adhesion G protein-coupled receptor E1; Belongs to the G-protein coupled receptor 2 family. (829 aa)
	VIPR1	Vasoactive intestinal peptide receptor 1; Belongs to the G-protein coupled receptor 2 family. (457 aa)
	CALCRL	Calcitonin receptor like receptor; Belongs to the G-protein coupled receptor 2 family. (461 aa)
	ADGRA1	G_PROTEIN_RECEP_F2_4 domain-containing protein; Belongs to the G-protein coupled receptor 2 family. (1268 aa)
	CELSR1	Cadherin EGF LAG seven-pass G-type receptor 1; Belongs to the G-protein coupled receptor 2 family. (2892 aa)
	ADGRB3	Adhesion G protein-coupled receptor B3; Belongs to the G-protein coupled receptor 2 family. (1522 aa)
	CELSR2	Cadherin EGF LAG seven-pass G-type receptor 2; Belongs to the G-protein coupled receptor 2 family. (2911 aa)
	ADGRB2	Adhesion G protein-coupled receptor B2; Belongs to the G-protein coupled receptor 2 family. (1585 aa)
	GHRHR	Growth hormone releasing hormone receptor; Belongs to the G-protein coupled receptor 2 family. (423 aa)
	ENSGGOP00000043687	G_PROTEIN_RECEP_F2_4 domain-containing protein; Belongs to the G-protein coupled receptor 2 family. (416 aa)
	GPR157	G protein-coupled receptor 157. (323 aa)
	ENSGGOP00000041818	Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (446 aa)
	VIPR2	Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (552 aa)
	ENSGGOP00000041051	Adhesion G protein-coupled receptor A2; Belongs to the G-protein coupled receptor 2 family. (1242 aa)
	ADGRD1	Adhesion G protein-coupled receptor D1; Belongs to the G-protein coupled receptor 2 family. (906 aa)
	CRHR1	Corticotropin releasing hormone receptor 1; Belongs to the G-protein coupled receptor 2 family. (444 aa)
	ADGRE5	Adhesion G protein-coupled receptor E5; Belongs to the G-protein coupled receptor 2 family. (835 aa)
	ADGRG2	Adhesion G protein-coupled receptor G2; Belongs to the G-protein coupled receptor 2 family. (1013 aa)
	CELSR3	Cadherin EGF LAG seven-pass G-type receptor 3; Belongs to the G-protein coupled receptor 2 family. (3312 aa)
	ADGRL3	Adhesion G protein-coupled receptor L3; Belongs to the G-protein coupled receptor 2 family. (1580 aa)
	CALCR	Calcitonin receptor; Belongs to the G-protein coupled receptor 2 family. (509 aa)
	ENSGGOP00000029832	Adhesion G protein-coupled receptor E3; Belongs to the G-protein coupled receptor 2 family. (638 aa)
	ADGRL1	Adhesion G protein-coupled receptor L1; Belongs to the G-protein coupled receptor 2 family. (1681 aa)
	PTH1R	Parathyroid hormone 1 receptor; Belongs to the G-protein coupled receptor 2 family. (593 aa)
	G3SIL0_GORGO	Adhesion G protein-coupled receptor B1; Belongs to the G-protein coupled receptor 2 family. (1570 aa)
	ADGRG4	Adhesion G protein-coupled receptor G4; Belongs to the G-protein coupled receptor 2 family. (3079 aa)
	ADGRA3	Adhesion G protein-coupled receptor A3; Belongs to the G-protein coupled receptor 2 family. (1321 aa)
	ADGRF1	Adhesion G protein-coupled receptor F1; Belongs to the G-protein coupled receptor 2 family. (910 aa)
	ADGRG6	Adhesion G protein-coupled receptor G6; Belongs to the G-protein coupled receptor 2 family. (1250 aa)
	CRHR2	Corticotropin releasing hormone receptor 2; Belongs to the G-protein coupled receptor 2 family. (438 aa)
	SCTR	Secretin receptor; Belongs to the G-protein coupled receptor 2 family. (440 aa)
	ADGRL2	Adhesion G protein-coupled receptor L2; Belongs to the G-protein coupled receptor 2 family. (1480 aa)

Your Current Organism:

Gorilla gorilla

NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADGRA1	ADGRF1	ENSGGOP00000002236	ENSGGOP00000026586	G_PROTEIN_RECEP_F2_4 domain-containing protein; Belongs to the G-protein coupled receptor 2 family.	Adhesion G protein-coupled receptor F1; Belongs to the G-protein coupled receptor 2 family.	0.481
ADGRA1	ADGRF4	ENSGGOP00000002236	ENSGGOP00000013016	G_PROTEIN_RECEP_F2_4 domain-containing protein; Belongs to the G-protein coupled receptor 2 family.	Adhesion G protein-coupled receptor F4; Belongs to the G-protein coupled receptor 2 family.	0.430
ADGRA1	ADGRG1	ENSGGOP00000002236	ENSGGOP00000008255	G_PROTEIN_RECEP_F2_4 domain-containing protein; Belongs to the G-protein coupled receptor 2 family.	Adhesion G-protein coupled receptor G1; Receptor involved in cell adhesion and probably in cell-cell interactions. Mediates cell matrix adhesion in developing neurons and hematopoietic stem cells. Receptor for collagen III/COL3A1 in the developing brain and involved in regulation of cortical development, specifically in maintenance of the pial basement membrane integrity and in cortical lamination. Binding to the COL3A1 ligand inhibits neuronal migration and activates the RhoA pathway by coupling to GNA13 and possibly GNA12. Plays a role in the maintenance of hematopoietic stem cells a [...]	0.424
ADGRA1	ADGRG3	ENSGGOP00000002236	ENSGGOP00000008266	G_PROTEIN_RECEP_F2_4 domain-containing protein; Belongs to the G-protein coupled receptor 2 family.	Adhesion G protein-coupled receptor G3; Belongs to the G-protein coupled receptor 2 family.	0.490
ADGRA1	ADGRG7	ENSGGOP00000002236	ENSGGOP00000010618	G_PROTEIN_RECEP_F2_4 domain-containing protein; Belongs to the G-protein coupled receptor 2 family.	Adhesion G protein-coupled receptor G7; Belongs to the G-protein coupled receptor 2 family.	0.480
ADGRA1	ADGRL1	ENSGGOP00000002236	ENSGGOP00000029196	G_PROTEIN_RECEP_F2_4 domain-containing protein; Belongs to the G-protein coupled receptor 2 family.	Adhesion G protein-coupled receptor L1; Belongs to the G-protein coupled receptor 2 family.	0.705
ADGRA1	ADGRL2	ENSGGOP00000002236	ENSGGOP00000024067	G_PROTEIN_RECEP_F2_4 domain-containing protein; Belongs to the G-protein coupled receptor 2 family.	Adhesion G protein-coupled receptor L2; Belongs to the G-protein coupled receptor 2 family.	0.688
ADGRA1	ADGRL3	ENSGGOP00000002236	ENSGGOP00000031604	G_PROTEIN_RECEP_F2_4 domain-containing protein; Belongs to the G-protein coupled receptor 2 family.	Adhesion G protein-coupled receptor L3; Belongs to the G-protein coupled receptor 2 family.	0.687
ADGRA1	G3R0T7_GORGO	ENSGGOP00000002236	ENSGGOP00000008783	G_PROTEIN_RECEP_F2_4 domain-containing protein; Belongs to the G-protein coupled receptor 2 family.	Adhesion G protein-coupled receptor D2; Belongs to the G-protein coupled receptor 2 family.	0.491
ADGRA1	G3R6D2_GORGO	ENSGGOP00000002236	ENSGGOP00000010881	G_PROTEIN_RECEP_F2_4 domain-containing protein; Belongs to the G-protein coupled receptor 2 family.	Adhesion G protein-coupled receptor F3; Belongs to the G-protein coupled receptor 2 family.	0.481
ADGRA1	SCTR	ENSGGOP00000002236	ENSGGOP00000024928	G_PROTEIN_RECEP_F2_4 domain-containing protein; Belongs to the G-protein coupled receptor 2 family.	Secretin receptor; Belongs to the G-protein coupled receptor 2 family.	0.627
ADGRA3	ADGRL1	ENSGGOP00000026663	ENSGGOP00000029196	Adhesion G protein-coupled receptor A3; Belongs to the G-protein coupled receptor 2 family.	Adhesion G protein-coupled receptor L1; Belongs to the G-protein coupled receptor 2 family.	0.723
ADGRA3	ADGRL2	ENSGGOP00000026663	ENSGGOP00000024067	Adhesion G protein-coupled receptor A3; Belongs to the G-protein coupled receptor 2 family.	Adhesion G protein-coupled receptor L2; Belongs to the G-protein coupled receptor 2 family.	0.693
ADGRA3	ADGRL3	ENSGGOP00000026663	ENSGGOP00000031604	Adhesion G protein-coupled receptor A3; Belongs to the G-protein coupled receptor 2 family.	Adhesion G protein-coupled receptor L3; Belongs to the G-protein coupled receptor 2 family.	0.687
ADGRF1	ADGRA1	ENSGGOP00000026586	ENSGGOP00000002236	Adhesion G protein-coupled receptor F1; Belongs to the G-protein coupled receptor 2 family.	G_PROTEIN_RECEP_F2_4 domain-containing protein; Belongs to the G-protein coupled receptor 2 family.	0.481
ADGRF1	ENSGGOP00000041051	ENSGGOP00000026586	ENSGGOP00000041051	Adhesion G protein-coupled receptor F1; Belongs to the G-protein coupled receptor 2 family.	Adhesion G protein-coupled receptor A2; Belongs to the G-protein coupled receptor 2 family.	0.413
ADGRF4	ADGRA1	ENSGGOP00000013016	ENSGGOP00000002236	Adhesion G protein-coupled receptor F4; Belongs to the G-protein coupled receptor 2 family.	G_PROTEIN_RECEP_F2_4 domain-containing protein; Belongs to the G-protein coupled receptor 2 family.	0.430
ADGRG1	ADGRA1	ENSGGOP00000008255	ENSGGOP00000002236	Adhesion G-protein coupled receptor G1; Receptor involved in cell adhesion and probably in cell-cell interactions. Mediates cell matrix adhesion in developing neurons and hematopoietic stem cells. Receptor for collagen III/COL3A1 in the developing brain and involved in regulation of cortical development, specifically in maintenance of the pial basement membrane integrity and in cortical lamination. Binding to the COL3A1 ligand inhibits neuronal migration and activates the RhoA pathway by coupling to GNA13 and possibly GNA12. Plays a role in the maintenance of hematopoietic stem cells a [...]	G_PROTEIN_RECEP_F2_4 domain-containing protein; Belongs to the G-protein coupled receptor 2 family.	0.424
ADGRG1	ENSGGOP00000041818	ENSGGOP00000008255	ENSGGOP00000041818	Adhesion G-protein coupled receptor G1; Receptor involved in cell adhesion and probably in cell-cell interactions. Mediates cell matrix adhesion in developing neurons and hematopoietic stem cells. Receptor for collagen III/COL3A1 in the developing brain and involved in regulation of cortical development, specifically in maintenance of the pial basement membrane integrity and in cortical lamination. Binding to the COL3A1 ligand inhibits neuronal migration and activates the RhoA pathway by coupling to GNA13 and possibly GNA12. Plays a role in the maintenance of hematopoietic stem cells a [...]	Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family.	0.405
ADGRG1	SCTR	ENSGGOP00000008255	ENSGGOP00000024928	Adhesion G-protein coupled receptor G1; Receptor involved in cell adhesion and probably in cell-cell interactions. Mediates cell matrix adhesion in developing neurons and hematopoietic stem cells. Receptor for collagen III/COL3A1 in the developing brain and involved in regulation of cortical development, specifically in maintenance of the pial basement membrane integrity and in cortical lamination. Binding to the COL3A1 ligand inhibits neuronal migration and activates the RhoA pathway by coupling to GNA13 and possibly GNA12. Plays a role in the maintenance of hematopoietic stem cells a [...]	Secretin receptor; Belongs to the G-protein coupled receptor 2 family.	0.444