STRINGSTRING
LUM LUM ENSGGOP00000021036 ENSGGOP00000021036 TLR4 TLR4 CARMIL3 CARMIL3 G3REJ1_GORGO G3REJ1_GORGO LRRC42 LRRC42 NLRP13 NLRP13 LRRC23 LRRC23
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LUMLumican. (338 aa)
ENSGGOP00000021036annotation not available (839 aa)
TLR4Toll-like receptor 4; Cooperates with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Also involved in LPS-independent inflammatory responses triggered by free fatty acids, such as palmitate. In complex with TLR6, promotes sterile inflammation in monocytes/macrophages in response to oxidized low-density lipoprotein (oxLDL) or amyloid-beta 42. In this context, the initial signal is provided by oxLDL- or amyloid-beta 42-binding to [...] (839 aa)
CARMIL3Capping protein regulator and myosin 1 linker 3. (1372 aa)
G3REJ1_GORGOLeucine rich repeat containing 14. (493 aa)
LRRC42Leucine rich repeat containing 42. (428 aa)
NLRP13NLR family pyrin domain containing 13. (1036 aa)
LRRC23Leucine rich repeat containing 23. (357 aa)
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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