STRINGSTRING
IL6 IL6 APOL1 APOL1 G3QJI7_GORGO G3QJI7_GORGO CD4 CD4 APOL6 APOL6 IL13 IL13 IL4 IL4 G3QT76_GORGO G3QT76_GORGO IFNG IFNG TFRC TFRC CD1D CD1D IL10 IL10 PGK1 PGK1 TPI1 TPI1 G3RSR8_GORGO G3RSR8_GORGO ERVFRD-1 ERVFRD-1 HPR HPR APOA2 APOA2 ENSGGOP00000031881 ENSGGOP00000031881 PGK2 PGK2 ENSGGOP00000045956 ENSGGOP00000045956 ENSGGOP00000049071 ENSGGOP00000049071 ENSGGOP00000052223 ENSGGOP00000052223
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
IL6Interleukin 6. (234 aa)
APOL1Apolipoprotein L1. (414 aa)
G3QJI7_GORGOTriosephosphate isomerase. (210 aa)
CD4CD4 molecule. (458 aa)
APOL6Apolipoprotein L6. (343 aa)
IL13Interleukin 13. (170 aa)
IL4Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Belongs to the IL-4/IL-13 family. (153 aa)
G3QT76_GORGOTumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (166 aa)
TFRCTransferrin receptor. (760 aa)
CD1DCD1d molecule. (335 aa)
IL10Interleukin 10. (178 aa)
PGK1Phosphoglycerate kinase. (394 aa)
TPI1Triosephosphate isomerase; Triosephosphate isomerase is an extremely efficient metabolic enzyme that catalyzes the interconversion between dihydroxyacetone phosphate (DHAP) and D-glyceraldehyde-3-phosphate (G3P) in glycolysis and gluconeogenesis. (249 aa)
G3RSR8_GORGOHaptoglobin; Belongs to the peptidase S1 family. (371 aa)
ERVFRD-1Transmembrane protein; This endogenous retroviral envelope protein has retained its original fusogenic properties and participates in trophoblast fusion and the formation of a syncytium during placenta morphogenesis. The interaction with MFSD2A is apparently important for this process (By similarity). (538 aa)
HPRHaptoglobin-related protein; Belongs to the peptidase S1 family. (348 aa)
APOA2Truncated apolipoprotein A-II; May stabilize HDL (high density lipoprotein) structure by its association with lipids, and affect the HDL metabolism; Belongs to the apolipoprotein A2 family. (133 aa)
ENSGGOP00000031881Phosphoglycerate kinase. (384 aa)
PGK2Phosphoglycerate kinase. (417 aa)
ENSGGOP00000045956Triosephosphate isomerase. (273 aa)
ENSGGOP00000049071Phosphoglycerate kinase. (215 aa)
ENSGGOP00000052223Triosephosphate isomerase. (137 aa)
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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