STRINGSTRING
NFIL3 NFIL3 EBF1 EBF1 THPO THPO G3QDY6_GORGO G3QDY6_GORGO DNTT DNTT ETV6 ETV6 ETV5 ETV5 NOTCH3 NOTCH3 ETS1 ETS1 CD4 CD4 DLL1 DLL1 GATA2 GATA2 GATA3 GATA3 SPI1 SPI1 CD5 CD5 OAS2 OAS2 NGFR NGFR CD7 CD7 GAPDH GAPDH NOTCH1 NOTCH1 G3R4C9_GORGO G3R4C9_GORGO RASAL1 RASAL1 IKZF2 IKZF2 CTSG CTSG G3RB29_GORGO G3RB29_GORGO HES4 HES4 CD79A CD79A G3RHP3_GORGO G3RHP3_GORGO GFI1B GFI1B CD19 CD19 BCL11B BCL11B RUNX3 RUNX3 CPA3 CPA3 CD1A CD1A NRARP NRARP CD34 CD34 LYL1 LYL1 DLL4 DLL4 IL7R IL7R ENSGGOP00000031261 ENSGGOP00000031261 TAL1 TAL1 RUNX1 RUNX1 LMO2 LMO2 BCL11A BCL11A IL15 IL15 ZEB2 ZEB2 CD8B CD8B ENSGGOP00000045882 ENSGGOP00000045882
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NFIL3Nuclear factor interleukin-3-regulated protein; Acts as a transcriptional regulator that recognizes and binds to the sequence 5'-[GA]TTA[CT]GTAA[CT]-3', a sequence present in many cellular and viral promoters. Represses transcription from promoters with activating transcription factor (ATF) sites. Represses promoter activity in osteoblasts. Represses transcriptional activity of PER1. Represses transcriptional activity of PER2 via the B-site on the promoter. Activates transcription from the interleukin-3 promoter in T- cells. Competes for the same consensus-binding site with PAR DNA- bi [...] (462 aa)
EBF1EBF transcription factor 1. (591 aa)
THPOThrombopoietin. (353 aa)
G3QDY6_GORGOInterleukin 7. (179 aa)
DNTTDNA nucleotidylexotransferase; Template-independent DNA polymerase which catalyzes the random addition of deoxynucleoside 5'-triphosphate to the 3'-end of a DNA initiator. (509 aa)
ETV6ETS variant 6. (452 aa)
ETV5ETS variant 5. (510 aa)
NOTCH3Notch receptor 3. (2317 aa)
ETS1ETS proto-oncogene 1, transcription factor. (485 aa)
CD4CD4 molecule. (458 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (723 aa)
GATA2GATA binding protein 2. (480 aa)
GATA3GATA binding protein 3. (444 aa)
SPI1Spi-1 proto-oncogene. (271 aa)
CD5CD5 molecule. (495 aa)
OAS22'-5'-oligoadenylate synthetase 2. (687 aa)
NGFRNerve growth factor receptor. (427 aa)
CD7CD7 molecule. (240 aa)
GAPDHGlyceraldehyde-3-phosphate dehydrogenase. (335 aa)
NOTCH1Uncharacterized protein. (1606 aa)
G3R4C9_GORGODeltex E3 ubiquitin ligase 1. (540 aa)
RASAL1RAS protein activator like 1. (805 aa)
IKZF2IKAROS family zinc finger 2. (500 aa)
CTSGGranzyme H; Belongs to the peptidase S1 family. (246 aa)
G3RB29_GORGOGranzyme B; Belongs to the peptidase S1 family. (247 aa)
HES4Hes family bHLH transcription factor 4. (221 aa)
CD79ACD79a molecule. (226 aa)
G3RHP3_GORGOGlycophorin. (148 aa)
GFI1BGrowth factor independent 1B transcriptional repressor. (330 aa)
CD19CD19 molecule. (556 aa)
BCL11BBAF chromatin remodeling complex subunit BCL11B. (894 aa)
RUNX3Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (428 aa)
CPA3Carboxypeptidase A3. (417 aa)
CD1ACD1a molecule. (327 aa)
NRARPNOTCH regulated ankyrin repeat protein. (114 aa)
CD34CD34 molecule. (385 aa)
LYL1LYL1 basic helix-loop-helix family member. (280 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (685 aa)
IL7RInterleukin 7 receptor. (458 aa)
ENSGGOP00000031261Myocyte enhancer factor 2C. (483 aa)
TAL1TAL bHLH transcription factor 1, erythroid differentiation factor. (331 aa)
RUNX1Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (480 aa)
LMO2LIM domain only 2. (222 aa)
BCL11ABAF chromatin remodeling complex subunit BCL11A. (835 aa)
IL15Interleukin; Belongs to the IL-15/IL-21 family. (162 aa)
ZEB2Zinc finger E-box binding homeobox 2. (1252 aa)
CD8BIg-like domain-containing protein. (206 aa)
ENSGGOP00000045882Actin beta. (378 aa)
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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