STRINGSTRING
CLEC4A CLEC4A ENSGGOP00000046758 ENSGGOP00000046758 TEX11 TEX11 CEP250 CEP250 ENSGGOP00000040173 ENSGGOP00000040173 ENSGGOP00000038310 ENSGGOP00000038310 CD46 CD46 ENSGGOP00000034768 ENSGGOP00000034768 ENSGGOP00000034542 ENSGGOP00000034542 ENSGGOP00000033566 ENSGGOP00000033566 G3SCC9_GORGO G3SCC9_GORGO SCGB1D2 SCGB1D2 H3-3A H3-3A OAS1 OAS1 CENPA CENPA TRIM5 TRIM5 H3C13 H3C13 RNASEL RNASEL G3RV54_GORGO G3RV54_GORGO TSPAN8 TSPAN8 NLRP11 NLRP11 REC8 REC8 PARP9 PARP9 IL18 IL18 CATSPER1 CATSPER1 G3QFY0_GORGO G3QFY0_GORGO TLR8 TLR8 PCNT PCNT SAMHD1 SAMHD1 PGLYRP1 PGLYRP1 KIAA1328 KIAA1328 G3R3U7_GORGO G3R3U7_GORGO G3R284_GORGO G3R284_GORGO CD22 CD22 CLEC1A CLEC1A IFI16 IFI16 PASD1 PASD1 MS4A12 MS4A12 G3QQ88_GORGO G3QQ88_GORGO SPATA32 SPATA32 APOL6 APOL6 CD4 CD4 IL4R IL4R G3QK89_GORGO G3QK89_GORGO TMEM126B TMEM126B CENPT CENPT NDUFA10 NDUFA10 IL3 IL3 MUC13 MUC13
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CLEC4AC-type lectin domain family 4 member A. (237 aa)
ENSGGOP00000046758Caspase 1; Belongs to the peptidase C14A family. (404 aa)
TEX11Testis expressed 11. (940 aa)
CEP250Centrosomal protein 250. (2445 aa)
ENSGGOP00000040173Calumenin. (323 aa)
ENSGGOP00000038310Histone H3; Belongs to the histone H3 family. (136 aa)
CD46CD46 molecule. (399 aa)
ENSGGOP00000034768Histone H3; Belongs to the histone H3 family. (94 aa)
ENSGGOP00000034542Histone H3; Belongs to the histone H3 family. (115 aa)
ENSGGOP00000033566Histone H3; Belongs to the histone H3 family. (127 aa)
G3SCC9_GORGOHistone H3; Belongs to the histone H3 family. (136 aa)
SCGB1D2Secretoglobin family 1D member 2. (90 aa)
H3-3AHistone H3; Belongs to the histone H3 family. (136 aa)
OAS12'-5'-oligoadenylate synthetase 1. (414 aa)
CENPACentromere protein A. (140 aa)
TRIM5Tripartite motif-containing protein 5; Capsid-specific restriction factor that prevents infection from non-host-adapted retroviruses. Blocks viral replication early in the life cycle, after viral entry but before reverse transcription. In addition to acting as a capsid-specific restriction factor, also acts as a pattern recognition receptor that activates innate immune signaling in response to the retroviral capsid lattice. Binding to the viral capsid triggers its E3 ubiquitin ligase activity, and in concert with the heterodimeric ubiquitin conjugating enzyme complex UBE2V1- UBE2N (als [...] (493 aa)
H3C13Histone H3; Belongs to the histone H3 family. (136 aa)
RNASELRibonuclease L. (741 aa)
G3RV54_GORGOProtein tyrosine phosphatase receptor type C. (1306 aa)
TSPAN8Tetraspanin. (237 aa)
NLRP11NLR family pyrin domain containing 11. (952 aa)
REC8REC8 meiotic recombination protein. (547 aa)
PARP9Poly(ADP-ribose) polymerase family member 9. (819 aa)
IL18Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (193 aa)
CATSPER1Cation channel sperm associated 1. (780 aa)
G3QFY0_GORGOMajor histocompatibility complex, class II, DP alpha 1; Belongs to the MHC class II family. (260 aa)
TLR8Toll like receptor 8; Belongs to the Toll-like receptor family. (1059 aa)
PCNTPericentrin. (3315 aa)
SAMHD1SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1. (626 aa)
PGLYRP1Peptidoglycan-recognition protein; Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Involved in innate immunity. (196 aa)
KIAA1328KIAA1328. (579 aa)
G3R3U7_GORGOMitochondrial antiviral signaling protein. (481 aa)
G3R284_GORGOTripartite motif containing 60. (471 aa)
CD22B-cell receptor CD22; Mediates B-cell B-cell interactions. May be involved in the localization of B-cells in lymphoid tissues. Binds sialylated glycoproteins; one of which is CD45. Preferentially binds to alpha-2,6- linked sialic acid (By similarity). Upon ligand-induced tyrosine phosphorylation in the immune response seems to be involved in regulation of B-cell antigen receptor signaling. Plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that b [...] (847 aa)
CLEC1AC-type lectin domain family 1 member A. (280 aa)
IFI16Interferon gamma inducible protein 16. (785 aa)
PASD1PAS domain containing repressor 1. (770 aa)
MS4A12Membrane spanning 4-domains A12. (267 aa)
G3QQ88_GORGOKeratin associated protein 24-1. (254 aa)
SPATA32Spermatogenesis associated 32. (386 aa)
APOL6Apolipoprotein L6. (343 aa)
CD4CD4 molecule. (458 aa)
IL4RInterleukin 4 receptor. (825 aa)
G3QK89_GORGONapsin A aspartic peptidase; Belongs to the peptidase A1 family. (420 aa)
TMEM126BTransmembrane protein 126B. (230 aa)
CENPTCentromere protein T. (561 aa)
NDUFA10NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (429 aa)
IL3Interleukin-3; Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. Belongs to the IL-3 family. (152 aa)
MUC13Mucin 13, cell surface associated. (512 aa)
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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