(13 nodes) (2019) Indoxyl Sulfate Induces Apoptosis Through Oxidative Stress and Mitogen-Activated Protein Kinase Signaling Pathway Inhibition in Human Astrocytes. network (Gorilla gorilla)

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Your Input:
	DUSP8	Dual specificity phosphatase 8. (609 aa)
	HMOX1	Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. (289 aa)
	G3S8N6_GORGO	Gp_dh_C domain-containing protein. (175 aa)
	HSPA8	Heat shock protein family A (Hsp70) member 8; Belongs to the heat shock protein 70 family. (646 aa)
	DUSP16	Dual specificity phosphatase 16. (665 aa)
	IL6	Interleukin 6. (234 aa)
	NOS2	Nitric oxide synthase; Produces nitric oxide (NO). (1153 aa)
	PXDNL	Peroxidasin like. (1463 aa)
	PXDN	Peroxidasin. (1472 aa)
	GAPDH	Glyceraldehyde-3-phosphate dehydrogenase. (335 aa)
	DUSP1	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (367 aa)
	LMNA	Lamin A/C; Belongs to the intermediate filament family. (664 aa)
	GAPDHS	Glyceraldehyde-3-phosphate dehydrogenase. (408 aa)

Your Current Organism:

Gorilla gorilla

NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DUSP1	IL6	ENSGGOP00000006978	ENSGGOP00000018546	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Interleukin 6.	0.531
G3S8N6_GORGO	GAPDH	ENSGGOP00000024449	ENSGGOP00000009331	Gp_dh_C domain-containing protein.	Glyceraldehyde-3-phosphate dehydrogenase.	0.902
G3S8N6_GORGO	GAPDHS	ENSGGOP00000024449	ENSGGOP00000000127	Gp_dh_C domain-containing protein.	Glyceraldehyde-3-phosphate dehydrogenase.	0.905
GAPDH	G3S8N6_GORGO	ENSGGOP00000009331	ENSGGOP00000024449	Glyceraldehyde-3-phosphate dehydrogenase.	Gp_dh_C domain-containing protein.	0.902
GAPDH	GAPDHS	ENSGGOP00000009331	ENSGGOP00000000127	Glyceraldehyde-3-phosphate dehydrogenase.	Glyceraldehyde-3-phosphate dehydrogenase.	0.958
GAPDH	HMOX1	ENSGGOP00000009331	ENSGGOP00000046026	Glyceraldehyde-3-phosphate dehydrogenase.	Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase.	0.532
GAPDH	HSPA8	ENSGGOP00000009331	ENSGGOP00000020917	Glyceraldehyde-3-phosphate dehydrogenase.	Heat shock protein family A (Hsp70) member 8; Belongs to the heat shock protein 70 family.	0.858
GAPDH	IL6	ENSGGOP00000009331	ENSGGOP00000018546	Glyceraldehyde-3-phosphate dehydrogenase.	Interleukin 6.	0.726
GAPDH	LMNA	ENSGGOP00000009331	ENSGGOP00000000800	Glyceraldehyde-3-phosphate dehydrogenase.	Lamin A/C; Belongs to the intermediate filament family.	0.512
GAPDH	NOS2	ENSGGOP00000009331	ENSGGOP00000018225	Glyceraldehyde-3-phosphate dehydrogenase.	Nitric oxide synthase; Produces nitric oxide (NO).	0.430
GAPDH	PXDN	ENSGGOP00000009331	ENSGGOP00000012480	Glyceraldehyde-3-phosphate dehydrogenase.	Peroxidasin.	0.778
GAPDH	PXDNL	ENSGGOP00000009331	ENSGGOP00000017973	Glyceraldehyde-3-phosphate dehydrogenase.	Peroxidasin like.	0.778
GAPDHS	G3S8N6_GORGO	ENSGGOP00000000127	ENSGGOP00000024449	Glyceraldehyde-3-phosphate dehydrogenase.	Gp_dh_C domain-containing protein.	0.905
GAPDHS	GAPDH	ENSGGOP00000000127	ENSGGOP00000009331	Glyceraldehyde-3-phosphate dehydrogenase.	Glyceraldehyde-3-phosphate dehydrogenase.	0.958
GAPDHS	HSPA8	ENSGGOP00000000127	ENSGGOP00000020917	Glyceraldehyde-3-phosphate dehydrogenase.	Heat shock protein family A (Hsp70) member 8; Belongs to the heat shock protein 70 family.	0.412
GAPDHS	PXDN	ENSGGOP00000000127	ENSGGOP00000012480	Glyceraldehyde-3-phosphate dehydrogenase.	Peroxidasin.	0.442
GAPDHS	PXDNL	ENSGGOP00000000127	ENSGGOP00000017973	Glyceraldehyde-3-phosphate dehydrogenase.	Peroxidasin like.	0.443
HMOX1	GAPDH	ENSGGOP00000046026	ENSGGOP00000009331	Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase.	Glyceraldehyde-3-phosphate dehydrogenase.	0.532
HMOX1	IL6	ENSGGOP00000046026	ENSGGOP00000018546	Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase.	Interleukin 6.	0.597
HMOX1	NOS2	ENSGGOP00000046026	ENSGGOP00000018225	Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase.	Nitric oxide synthase; Produces nitric oxide (NO).	0.570