STRINGSTRING
ENSGGOP00000034542 ENSGGOP00000034542 RRM2 RRM2 ENSGGOP00000038310 ENSGGOP00000038310 MECP2 MECP2 ENSGGOP00000045882 ENSGGOP00000045882 GPC4 GPC4 RNASE1 RNASE1 EGF EGF GAPDH GAPDH HDAC1 HDAC1 SETDB1 SETDB1 HDAC3 HDAC3 PGK1 PGK1 H3C13 H3C13 H3-3A H3-3A G3SCC9_GORGO G3SCC9_GORGO ENSGGOP00000033566 ENSGGOP00000033566 ENSGGOP00000034768 ENSGGOP00000034768
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSGGOP00000034542Histone H3; Belongs to the histone H3 family. (115 aa)
RRM2Ribonucleotide reductase regulatory subunit M2. (389 aa)
ENSGGOP00000038310Histone H3; Belongs to the histone H3 family. (136 aa)
MECP2Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). (498 aa)
ENSGGOP00000045882Actin beta. (378 aa)
GPC4Glypican 4; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (556 aa)
RNASE1Ribonuclease pancreatic; Endonuclease that catalyzes the cleavage of RNA on the 3' side of pyrimidine nucleotides. Acts on single-stranded and double- stranded RNA (By similarity). (156 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1183 aa)
GAPDHGlyceraldehyde-3-phosphate dehydrogenase. (335 aa)
HDAC1Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (482 aa)
SETDB1SET domain bifurcated histone lysine methyltransferase 1. (1292 aa)
HDAC3Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (428 aa)
PGK1Phosphoglycerate kinase. (394 aa)
H3C13Histone H3; Belongs to the histone H3 family. (136 aa)
H3-3AHistone H3; Belongs to the histone H3 family. (136 aa)
G3SCC9_GORGOHistone H3; Belongs to the histone H3 family. (136 aa)
ENSGGOP00000033566Histone H3; Belongs to the histone H3 family. (127 aa)
ENSGGOP00000034768Histone H3; Belongs to the histone H3 family. (94 aa)
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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