(45 nodes) (2021) Molecular diversity of diencephalic astrocytes reveals adult astrogenesis regulated by Smad4. network (Gorilla gorilla)

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experimentally determined

Predicted Interactions

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Your Input:
	THRSP	Thyroid hormone responsive. (146 aa)
	CCN3	Cellular communication network factor 3. (357 aa)
	ATP1B2	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (290 aa)
	CHRDL1	Chordin like 1. (458 aa)
	SATB2	DNA-binding protein SATB. (733 aa)
	PTN	Pleiotrophin. (172 aa)
	SMAD3	Mothers against decapentaplegic homolog. (356 aa)
	ENSGGOP00000048297	Nuclear factor I A. (170 aa)
	PCNA	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
	ENSGGOP00000041668	Fibroblast growth factor receptor. (808 aa)
	NDRG2	NDRG family member 2. (381 aa)
	ALDH1L1	10-formyltetrahydrofolate dehydrogenase; In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily. (912 aa)
	FGF2	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (258 aa)
	CCNT2	Cyclin T2; Belongs to the cyclin family. (730 aa)
	GFAP	Glial fibrillary acidic protein; Belongs to the intermediate filament family. (505 aa)
	NEUROD6	Neurogenic differentiation factor. (337 aa)
	RPL22	Ribosomal protein L22. (128 aa)
	SLC2A1	Solute carrier family 2 member 1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (492 aa)
	G3RUR9_GORGO	Forkhead box B1. (279 aa)
	SOX10	HMG box domain-containing protein. (286 aa)
	TBR1	T-box brain transcription factor 1. (682 aa)
	NFIA	Nuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. (554 aa)
	G3RNX2_GORGO	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (246 aa)
	SOX9	SRY-box transcription factor 9. (509 aa)
	EMX2	Empty spiracles homeobox 2. (252 aa)
	CRYM	Crystallin mu. (314 aa)
	NTRK2	Tyrosine-protein kinase receptor. (767 aa)
	SMAD4	Mothers against decapentaplegic homolog. (552 aa)
	SMAD7	MH2 domain-containing protein. (211 aa)
	AQP4	Aquaporin 4; Belongs to the MIP/aquaporin (TC 1.A.8) family. (323 aa)
	ALDOC	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (364 aa)
	VIM	Vimentin; Belongs to the intermediate filament family. (466 aa)
	DKK3	Dickkopf WNT signaling pathway inhibitor 3. (338 aa)
	GAPDH	Glyceraldehyde-3-phosphate dehydrogenase. (335 aa)
	SLC16A2	Solute carrier family 16 member 2. (537 aa)
	LHX2	LIM homeobox 2. (406 aa)
	FOXJ1	Forkhead box J1. (421 aa)
	S100A6	Protein S100; Belongs to the S-100 family. (90 aa)
	G3QVJ2_GORGO	Collagen type XXIII alpha 1 chain. (540 aa)
	EGF	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1183 aa)
	SMAD2	Mothers against decapentaplegic homolog. (467 aa)
	SLC1A3	Amino acid transporter. (542 aa)
	HOPX	HOP homeobox. (112 aa)
	G3QPM1_GORGO	Neuronatin. (81 aa)
	AEBP1	AE binding protein 1. (985 aa)

Your Current Organism:

Gorilla gorilla

NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ALDH1L1	AQP4	ENSGGOP00000034873	ENSGGOP00000010219	10-formyltetrahydrofolate dehydrogenase; In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily.	Aquaporin 4; Belongs to the MIP/aquaporin (TC 1.A.8) family.	0.580
ALDH1L1	GFAP	ENSGGOP00000034873	ENSGGOP00000029457	10-formyltetrahydrofolate dehydrogenase; In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily.	Glial fibrillary acidic protein; Belongs to the intermediate filament family.	0.590
ALDH1L1	SLC1A3	ENSGGOP00000034873	ENSGGOP00000004566	10-formyltetrahydrofolate dehydrogenase; In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily.	Amino acid transporter.	0.644
ALDOC	GAPDH	ENSGGOP00000009481	ENSGGOP00000009331	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family.	Glyceraldehyde-3-phosphate dehydrogenase.	0.981
ALDOC	SLC1A3	ENSGGOP00000009481	ENSGGOP00000004566	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family.	Amino acid transporter.	0.449
AQP4	ALDH1L1	ENSGGOP00000010219	ENSGGOP00000034873	Aquaporin 4; Belongs to the MIP/aquaporin (TC 1.A.8) family.	10-formyltetrahydrofolate dehydrogenase; In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily.	0.580
AQP4	GFAP	ENSGGOP00000010219	ENSGGOP00000029457	Aquaporin 4; Belongs to the MIP/aquaporin (TC 1.A.8) family.	Glial fibrillary acidic protein; Belongs to the intermediate filament family.	0.620
AQP4	SLC1A3	ENSGGOP00000010219	ENSGGOP00000004566	Aquaporin 4; Belongs to the MIP/aquaporin (TC 1.A.8) family.	Amino acid transporter.	0.542
ATP1B2	G3QPM1_GORGO	ENSGGOP00000002676	ENSGGOP00000004518	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	Neuronatin.	0.540
CCN3	CHRDL1	ENSGGOP00000002735	ENSGGOP00000002456	Cellular communication network factor 3.	Chordin like 1.	0.405
CCNT2	SMAD4	ENSGGOP00000031995	ENSGGOP00000013332	Cyclin T2; Belongs to the cyclin family.	Mothers against decapentaplegic homolog.	0.455
CHRDL1	CCN3	ENSGGOP00000002456	ENSGGOP00000002735	Chordin like 1.	Cellular communication network factor 3.	0.405
CRYM	G3QVJ2_GORGO	ENSGGOP00000015933	ENSGGOP00000006764	Crystallin mu.	Collagen type XXIII alpha 1 chain.	0.407
CRYM	SLC16A2	ENSGGOP00000015933	ENSGGOP00000009250	Crystallin mu.	Solute carrier family 16 member 2.	0.544
EGF	ENSGGOP00000041668	ENSGGOP00000005698	ENSGGOP00000041668	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Fibroblast growth factor receptor.	0.833
EGF	FGF2	ENSGGOP00000005698	ENSGGOP00000033172	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.796
EGF	GAPDH	ENSGGOP00000005698	ENSGGOP00000009331	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Glyceraldehyde-3-phosphate dehydrogenase.	0.637
EGF	GFAP	ENSGGOP00000005698	ENSGGOP00000029457	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Glial fibrillary acidic protein; Belongs to the intermediate filament family.	0.618
EGF	NTRK2	ENSGGOP00000005698	ENSGGOP00000013959	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Tyrosine-protein kinase receptor.	0.840
EGF	SMAD2	ENSGGOP00000005698	ENSGGOP00000004612	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Mothers against decapentaplegic homolog.	0.451