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GSTO2 | Glutathione S-transferase omega 2; Belongs to the GST superfamily. (243 aa) | ||||
BCL2 | BCL2 apoptosis regulator. (239 aa) | ||||
XPA | XPA, DNA damage recognition and repair factor. (273 aa) | ||||
CASP9 | Caspase 9; Belongs to the peptidase C14A family. (446 aa) | ||||
G3QKY6_GORGO | Glutathione S-transferase alpha 5; Belongs to the GST superfamily. (193 aa) | ||||
ERBB2 | Receptor protein-tyrosine kinase. (1255 aa) | ||||
MGST2 | Microsomal glutathione S-transferase 2. (147 aa) | ||||
GSTO1 | Glutathione S-transferase omega 1; Belongs to the GST superfamily. (241 aa) | ||||
GSTA4 | Glutathione S-transferase alpha 4; Belongs to the GST superfamily. (222 aa) | ||||
PMAIP1 | Uncharacterized protein. (150 aa) | ||||
BIRC3 | Baculoviral IAP repeat containing 3. (604 aa) | ||||
MGST1 | Microsomal glutathione S-transferase 1. (155 aa) | ||||
MSH2 | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (934 aa) | ||||
AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) | ||||
BIRC2 | Baculoviral IAP repeat containing 2. (618 aa) | ||||
XIAP | Uncharacterized protein. (371 aa) | ||||
GSTT2B | Uncharacterized protein; Belongs to the GST superfamily. (244 aa) | ||||
PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) | ||||
PIK3CB | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1041 aa) | ||||
GSTM3 | Glutathione S-transferase. (225 aa) | ||||
BAX | BCL2 associated X, apoptosis regulator. (217 aa) | ||||
ATM | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3023 aa) | ||||
G3R4P4_GORGO | Uncharacterized protein. (240 aa) | ||||
BID | BH3-interacting domain death agonist; Counters the protective effect of Bcl-2. (195 aa) | ||||
GSTM5 | Glutathione S-transferase. (218 aa) | ||||
MGST3 | Microsomal glutathione S-transferase 3. (166 aa) | ||||
ATP7B | ATPase copper transporting beta. (1470 aa) | ||||
MLH1 | MutL homolog 1. (756 aa) | ||||
G3RQE7_GORGO | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) | ||||
ABCC2 | ATP binding cassette subfamily C member 2. (1545 aa) | ||||
CDKN1A | Cyclin dependent kinase inhibitor 1A. (164 aa) | ||||
BAK1 | BCL2 antagonist/killer 1. (211 aa) | ||||
MSH6 | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1360 aa) | ||||
PIK3R3 | Uncharacterized protein. (507 aa) | ||||
FADD | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (208 aa) | ||||
BCL2L1 | BCL2 like 1. (233 aa) | ||||
TOP2B | DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1562 aa) | ||||
CASP3 | Caspase 3; Belongs to the peptidase C14A family. (277 aa) | ||||
MAPK3 | Mitogen-activated protein kinase. (322 aa) | ||||
ATP7A | ATPase copper transporting alpha. (1500 aa) | ||||
MAP3K5 | Mitogen-activated protein kinase kinase kinase 5. (1374 aa) | ||||
TOP2A | DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1531 aa) | ||||
BRCA1 | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] (1824 aa) | ||||
GSTM1 | Glutathione S-transferase. (218 aa) | ||||
PDPK1 | Protein kinase domain-containing protein. (347 aa) | ||||
FASLG | Fas ligand; Belongs to the tumor necrosis factor family. (280 aa) | ||||
GSTP1 | Glutathione S-transferase pi 1; Belongs to the GST superfamily. (210 aa) | ||||
FAS | Fas cell surface death receptor. (340 aa) | ||||
CYCS | Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain (By similarity). (105 aa) | ||||
G3SKC3_GORGO | Glutathione S-transferase alpha 2. (222 aa) | ||||
TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (403 aa) | ||||
CDKN2A | Cyclin dependent kinase inhibitor 2A. (167 aa) | ||||
AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) | ||||
APAF1 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1248 aa) | ||||
ERCC1 | ERCC excision repair 1, endonuclease non-catalytic subunit. (297 aa) | ||||
BAD | BCL2 associated agonist of cell death. (168 aa) | ||||
MAPK1 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa) | ||||
POLH | UmuC domain-containing protein. (415 aa) | ||||
ENSGGOP00000041700 | GST N-terminal domain-containing protein. (67 aa) | ||||
ENSGGOP00000043235 | GST N-terminal domain-containing protein. (67 aa) | ||||
SLC31A1 | Solute carrier family 31 member 1. (190 aa) | ||||
ENSGGOP00000049412 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (117 aa) | ||||
PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (723 aa) | ||||
BBC3 | Uncharacterized protein. (101 aa) | ||||
GSTM4 | Uncharacterized protein; Belongs to the GST superfamily. (218 aa) |