Your Input: | |
| | SPTA1 | Spectrin alpha, erythrocytic 1. (2419 aa) |
| | FOS | Fos proto-oncogene, AP-1 transcription factor subunit. (380 aa) |
| | BCL2 | BCL2 apoptosis regulator. (239 aa) |
| | LMNA | Lamin A/C; Belongs to the intermediate filament family. (664 aa) |
| | IL3 | Interleukin-3; Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. Belongs to the IL-3 family. (152 aa) |
| | CTSB | Cathepsin B; Belongs to the peptidase C1 family. (339 aa) |
| | EIF2S1 | Eukaryotic translation initiation factor 2 subunit alpha. (315 aa) |
| | PRF1 | Perforin 1. (555 aa) |
| | CASP9 | Caspase 9; Belongs to the peptidase C14A family. (446 aa) |
| | DDIT3 | DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (169 aa) |
| | CTSC | Cathepsin C; Belongs to the peptidase C1 family. (463 aa) |
| | TRAF1 | TNF receptor-associated factor. (416 aa) |
| | PARP4 | Poly [ADP-ribose] polymerase. (1691 aa) |
| | CASP2 | Caspase 2; Belongs to the peptidase C14A family. (452 aa) |
| | MAP2K1 | Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa) |
| | MAP3K14 | Mitogen-activated protein kinase kinase kinase 14. (947 aa) |
| | IKBKG | Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (487 aa) |
| | GADD45G | Growth arrest and DNA damage inducible gamma. (159 aa) |
| | DIABLO | Uncharacterized protein. (166 aa) |
| | PMAIP1 | Uncharacterized protein. (150 aa) |
| | ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1. (2706 aa) |
| | BIRC3 | Baculoviral IAP repeat containing 3. (604 aa) |
| | HRK | Activator of apoptosis harakiri; Promotes apoptosis. (91 aa) |
| | HTRA2 | HtrA serine peptidase 2. (458 aa) |
| | ERN1 | Endoplasmic reticulum to nucleus signaling 1. (977 aa) |
| | IKBKB | Inhibitor of nuclear factor kappa B kinase subunit beta. (762 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) |
| | BIRC2 | Baculoviral IAP repeat containing 2. (618 aa) |
| | SEPTIN4 | Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (1012 aa) |
| | XIAP | Uncharacterized protein. (371 aa) |
| | G3R0F2_GORGO | Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa) |
| | CHUK | IKKbetaNEMObind domain-containing protein. (434 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) |
| | NFKBIA | NFKB inhibitor alpha. (317 aa) |
| | PIK3CB | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1041 aa) |
| | ATF4 | Activating transcription factor 4. (351 aa) |
| | BAX | BCL2 associated X, apoptosis regulator. (217 aa) |
| | ATM | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3023 aa) |
| | BID | BH3-interacting domain death agonist; Counters the protective effect of Bcl-2. (195 aa) |
| | GADD45A | Growth arrest and DNA damage inducible alpha. (165 aa) |
| | CTSW | Cathepsin W; Belongs to the peptidase C1 family. (376 aa) |
| | CFLAR | CASP8 and FADD like apoptosis regulator; Belongs to the peptidase C14A family. (480 aa) |
| | TNFRSF10B | TNF receptor superfamily member 10b. (440 aa) |
| | EIF2AK3 | Eukaryotic translation initiation factor 2 alpha kinase 3. (1116 aa) |
| | TRADD | Death domain-containing protein. (251 aa) |
| | G3R8R1_GORGO | Caspase 12 (gene/pseudogene); Belongs to the peptidase C14A family. (341 aa) |
| | CTSH | Cathepsin H; Belongs to the peptidase C1 family. (335 aa) |
| | CASP10 | Caspase 10; Belongs to the peptidase C14A family. (523 aa) |
| | PARP3 | Poly [ADP-ribose] polymerase. (538 aa) |
| | RIPK1 | Receptor interacting serine/threonine kinase 1. (671 aa) |
| | DFFA | DNA fragmentation factor subunit alpha. (331 aa) |
| | G3RB29_GORGO | Granzyme B; Belongs to the peptidase S1 family. (247 aa) |
| | DFFB | DNA fragmentation factor subunit beta. (338 aa) |
| | ACTG1 | Actin gamma 1. (375 aa) |
| | ENDOG | Endonuclease. (297 aa) |
| | TP53AIP1 | Tumor protein p53 regulated apoptosis inducing protein 1. (124 aa) |
| | MCL1 | MCL1 apoptosis regulator, BCL2 family member. (350 aa) |
| | CTSO | Cathepsin O; Belongs to the peptidase C1 family. (321 aa) |
| | CTSZ | Cathepsin Z; Belongs to the peptidase C1 family. (303 aa) |
| | PTPN13 | Protein tyrosine phosphatase non-receptor type 13. (2490 aa) |
| | G3RMA0_GORGO | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa) |
| | G3RQE7_GORGO | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | G3RQF7_GORGO | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa) |
| | PARP2 | Poly [ADP-ribose] polymerase. (570 aa) |
| | NFKB1 | Nuclear factor kappa B subunit 1. (969 aa) |
| | BAK1 | BCL2 antagonist/killer 1. (211 aa) |
| | PIK3R3 | Uncharacterized protein. (507 aa) |
| | FADD | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (208 aa) |
| | LMNB1 | Lamin B1; Belongs to the intermediate filament family. (586 aa) |
| | BCL2L1 | BCL2 like 1. (233 aa) |
| | CASP3 | Caspase 3; Belongs to the peptidase C14A family. (277 aa) |
| | CTSK | Cathepsin K; Belongs to the peptidase C1 family. (329 aa) |
| | MAPK3 | Mitogen-activated protein kinase. (322 aa) |
| | GADD45B | Growth arrest and DNA damage inducible beta. (160 aa) |
| | MAP3K5 | Mitogen-activated protein kinase kinase kinase 5. (1374 aa) |
| | TUBA3C | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (450 aa) |
| | MAPK9 | Mitogen-activated protein kinase. (424 aa) |
| | TUBAL3 | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (446 aa) |
| | CAPN1 | Calpain 1; Belongs to the peptidase C2 family. (729 aa) |
| | PDPK1 | Protein kinase domain-containing protein. (347 aa) |
| | FASLG | Fas ligand; Belongs to the tumor necrosis factor family. (280 aa) |
| | ITPR3 | Inositol 1,4,5-trisphosphate receptor type 3. (2677 aa) |
| | PARP1 | Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1014 aa) |
| | DAXX | Death domain associated protein. (743 aa) |
| | G3SEM1_GORGO | Cathepsin L; Belongs to the peptidase C1 family. (333 aa) |
| | TNFRSF1A | TNF receptor superfamily member 1A. (455 aa) |
| | FAS | Fas cell surface death receptor. (340 aa) |
| | RAF1 | Raf-1 proto-oncogene, serine/threonine kinase. (630 aa) |
| | RELA | RELA proto-oncogene, NF-kB subunit. (551 aa) |
| | CYCS | Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain (By similarity). (105 aa) |
| | CASP6 | Caspase 6; Belongs to the peptidase C14A family. (293 aa) |
| | TUBA8 | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (449 aa) |
| | PIDD1 | P53-induced death domain protein 1. (910 aa) |
| | SPTAN1 | Spectrin alpha, non-erythrocytic 1. (2498 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (403 aa) |
| | DAB2IP | DAB2 interacting protein. (1155 aa) |
| | ENSGGOP00000032596 | CCHC NOA-type domain-containing protein. (417 aa) |
| | NRAS | NRAS proto-oncogene, GTPase. (189 aa) |
| | AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) |
| | NGF | Beta-nerve growth factor; Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades to regulate neuronal proliferation, differentiation and survival (By similarity). The immature NGF precursor (proNGF) functions as ligand for the heterodimeric receptor formed by SORCS2 and NGFR, and activates cellular signaling cascades that lead to inactivation of RAC1 and/or RAC2, reorganization of the actin cytoskeleton and neuronal growth cone colla [...] (123 aa) |
| | BCL2A1 | BCL2 related protein A1. (196 aa) |
| | APAF1 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1248 aa) |
| | TUBA4A | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (448 aa) |
| | HRAS | HRas proto-oncogene, GTPase. (189 aa) |
| | ITPR2 | Inositol 1,4,5-trisphosphate receptor type 2. (2714 aa) |
| | BAD | BCL2 associated agonist of cell death. (168 aa) |
| | NTRK1 | Tyrosine-protein kinase receptor. (796 aa) |
| | MAPK1 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa) |
| | CSF2RB | Colony stimulating factor 2 receptor beta common subunit. (904 aa) |
| | CASP7 | Caspase 7; Belongs to the peptidase C14A family. (388 aa) |
| | ENSGGOP00000045882 | Actin beta. (378 aa) |
| | CTSV | Cathepsin V; Belongs to the peptidase C1 family. (334 aa) |
| | TNFRSF10A | TNF receptor superfamily member 10a. (468 aa) |
| | BCL2L11 | Bcl-2-like protein 11; Induces apoptosis and anoikis. Belongs to the Bcl-2 family. (198 aa) |
| | MAPK8 | Mitogen-activated protein kinase. (427 aa) |
| | ENSGGOP00000049412 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (117 aa) |
| | PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (723 aa) |
| | BBC3 | Uncharacterized protein. (101 aa) |
| | MAPK10 | Mitogen-activated protein kinase. (551 aa) |
