Your Input: | |
| | BCL2 | BCL2 apoptosis regulator. (239 aa) |
| | STAT6 | Signal transducer and activator of transcription. (847 aa) |
| | G3QH59_GORGO | Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. (372 aa) |
| | VDAC3 | Voltage dependent anion channel 3. (284 aa) |
| | SMPD1 | Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide. (625 aa) |
| | CHMP7 | Charged multivesicular body protein 7. (453 aa) |
| | HIST2H2AA3 | Histone H2A; Belongs to the histone H2A family. (130 aa) |
| | H2AC20 | Histone H2A; Belongs to the histone H2A family. (129 aa) |
| | G3QKC9_GORGO | Histone H2A; Belongs to the histone H2A family. (130 aa) |
| | TNFAIP3 | TNF alpha induced protein 3. (790 aa) |
| | IL1A | Interleukin-1; Belongs to the IL-1 family. (271 aa) |
| | RIPK3 | Receptor interacting serine/threonine kinase 3. (518 aa) |
| | NLRP3 | NLR family pyrin domain containing 3. (1028 aa) |
| | BIRC3 | Baculoviral IAP repeat containing 3. (604 aa) |
| | G3QT16_GORGO | Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. (372 aa) |
| | TYK2 | Tyrosine-protein kinase. (1188 aa) |
| | IFNG | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (166 aa) |
| | IL1B | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (269 aa) |
| | VPS4B | Vacuolar protein sorting 4 homolog B; Belongs to the AAA ATPase family. (444 aa) |
| | SP100 | Nuclear autoantigen Sp-100; Together with PML, this tumor suppressor is a major constituent of the PML bodies, a subnuclear organelle involved in a large number of physiological processes including cell growth, differentiation and apoptosis. Functions as a transcriptional coactivator of ETS1 and ETS2. Under certain conditions, it may also act as a corepressor of ETS1 preventing its binding to DNA. Through the regulation of ETS1 it may play a role in angiogenesis, controlling endothelial cell motility and invasion. Through interaction with the MRN complex it may be involved in the regul [...] (209 aa) |
| | G3QXY3_GORGO | Cytochrome b-245 beta chain. (570 aa) |
| | G3QYE9_GORGO | Histone H2A; Belongs to the histone H2A family. (143 aa) |
| | BIRC2 | Baculoviral IAP repeat containing 2. (618 aa) |
| | CYLD | CYLD lysine 63 deubiquitinase; Belongs to the peptidase C19 family. (956 aa) |
| | IFNGR1 | Interferon gamma receptor 1. (489 aa) |
| | XIAP | Uncharacterized protein. (371 aa) |
| | HSP90AB1 | Heat shock protein 90 alpha family class B member 1. (724 aa) |
| | RBCK1 | Uncharacterized protein. (204 aa) |
| | BAX | BCL2 associated X, apoptosis regulator. (217 aa) |
| | BID | BH3-interacting domain death agonist; Counters the protective effect of Bcl-2. (195 aa) |
| | VDAC1 | Voltage dependent anion channel 1. (289 aa) |
| | SPATA2L | Spermatogenesis associated 2 like. (424 aa) |
| | CFLAR | CASP8 and FADD like apoptosis regulator; Belongs to the peptidase C14A family. (480 aa) |
| | ZBP1 | Z-DNA binding protein 1. (429 aa) |
| | TNFRSF10B | TNF receptor superfamily member 10b. (440 aa) |
| | PLA2G4E | Phospholipase A2. (868 aa) |
| | TRADD | Death domain-containing protein. (251 aa) |
| | PLA2G4A | Phospholipase A2. (749 aa) |
| | RIPK1 | Receptor interacting serine/threonine kinase 1. (671 aa) |
| | PYGM | Alpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (840 aa) |
| | PPID | Peptidylprolyl isomerase D. (370 aa) |
| | TRAF5 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (557 aa) |
| | FAF1 | Fas associated factor 1. (650 aa) |
| | SLC25A31 | Solute carrier family 25 member 31; Belongs to the mitochondrial carrier (TC 2.A.29) family. (315 aa) |
| | SLC25A5 | Solute carrier family 25 member 5; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa) |
| | PYGB | Alpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (762 aa) |
| | GLUD1 | Glutamate dehydrogenase 1; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (558 aa) |
| | RNF31 | Uncharacterized protein. (1072 aa) |
| | IRF9 | Interferon regulatory factor 9. (392 aa) |
| | JAK1 | Tyrosine-protein kinase. (1154 aa) |
| | CHMP5 | Charged multivesicular body protein 5. (219 aa) |
| | CHMP4C | Charged multivesicular body protein 4C. (233 aa) |
| | PYCARD | PYD and CARD domain containing. (195 aa) |
| | IFNB1 | Interferon beta 1. (187 aa) |
| | G3RM71_GORGO | Histone H2A; Belongs to the histone H2A family. (128 aa) |
| | FTH1 | Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. (183 aa) |
| | PYGL | Alpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (847 aa) |
| | HIST1H2AK | Histone H2A; Belongs to the histone H2A family. (130 aa) |
| | CHMP2B | Charged multivesicular body protein 2B. (228 aa) |
| | G3RQE0_GORGO | Histone H2A; Belongs to the histone H2A family. (129 aa) |
| | PGAM5 | PGAM family member 5, mitochondrial serine/threonine protein phosphatase. (289 aa) |
| | EIF2AK2 | Eukaryotic translation initiation factor 2 alpha kinase 2. (551 aa) |
| | G3RVS4_GORGO | Signal transducer and activator of transcription. (787 aa) |
| | PPIA | Peptidyl-prolyl cis-trans isomerase A, N-terminally processed; PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding; Belongs to the cyclophilin-type PPIase family. PPIase A subfamily. (165 aa) |
| | FADD | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (208 aa) |
| | SQSTM1 | Sequestosome 1. (440 aa) |
| | CHMP4B-2 | Uncharacterized protein. (201 aa) |
| | STAT3 | Signal transducer and activator of transcription. (781 aa) |
| | SHARPIN | SHANK associated RH domain interactor. (387 aa) |
| | TLR4 | Toll-like receptor 4; Cooperates with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Also involved in LPS-independent inflammatory responses triggered by free fatty acids, such as palmitate. In complex with TLR6, promotes sterile inflammation in monocytes/macrophages in response to oxidized low-density lipoprotein (oxLDL) or amyloid-beta 42. In this context, the initial signal is provided by oxLDL- or amyloid-beta 42-binding to [...] (839 aa) |
| | PLA2G4F | Phospholipase A2. (849 aa) |
| | G3S148_GORGO | Uncharacterized protein. (157 aa) |
| | IFNA2 | Interferon alpha 2. (170 aa) |
| | G3S4Z2_GORGO | Uncharacterized protein. (119 aa) |
| | G3S4Z9_GORGO | Histone H2A; Belongs to the histone H2A family. (130 aa) |
| | MAPK9 | Mitogen-activated protein kinase. (424 aa) |
| | TICAM2 | Toll like receptor adaptor molecule 2. (235 aa) |
| | CHMP2A | Charged multivesicular body protein 2A. (222 aa) |
| | SPATA2 | Spermatogenesis associated 2. (520 aa) |
| | CAPN1 | Calpain 1; Belongs to the peptidase C2 family. (729 aa) |
| | FASLG | Fas ligand; Belongs to the tumor necrosis factor family. (280 aa) |
| | PARP1 | Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1014 aa) |
| | TRPM7 | Transient receptor potential cation channel subfamily M member 7. (1822 aa) |
| | STAT1 | Signal transducer and activator of transcription. (777 aa) |
| | TNFRSF1A | TNF receptor superfamily member 1A. (455 aa) |
| | FAS | Fas cell surface death receptor. (340 aa) |
| | HMGB1 | Uncharacterized protein. (215 aa) |
| | TLR3 | Toll-like receptor 3 precursor; Belongs to the Toll-like receptor family. (904 aa) |
| | ALOX15 | Arachidonate 15-lipoxygenase. (662 aa) |
| | G3SHJ3_GORGO | Histone H2A; Belongs to the histone H2A family. (130 aa) |
| | GLUL | Glutamine synthetase. (373 aa) |
| | ENSGGOP00000029461 | Histone H2A; Belongs to the histone H2A family. (130 aa) |
| | ENSGGOP00000029696 | Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (155 aa) |
| | CAMK2A | Calcium/calmodulin dependent protein kinase II alpha; Belongs to the protein kinase superfamily. (489 aa) |
| | ENSGGOP00000031121 | Uncharacterized protein. (361 aa) |
| | CAMK2B | Calcium/calmodulin dependent protein kinase II beta. (644 aa) |
| | IFNAR1 | Interferon alpha and beta receptor subunit 1. (558 aa) |
| | MLKL | Uncharacterized protein. (178 aa) |
| | ENSGGOP00000035522 | Interferon alpha 1. (198 aa) |
| | G3RKB0_GORGO | Histone H2A; Belongs to the histone H2A family. (130 aa) |
| | VDAC2 | Voltage dependent anion channel 2. (308 aa) |
| | ENSGGOP00000038183 | Histone H2A; Belongs to the histone H2A family. (128 aa) |
| | SLC25A4 | Solute carrier family 25 member 4; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa) |
| | CHMP6 | Uncharacterized protein. (224 aa) |
| | IL33 | Interleukin 33. (270 aa) |
| | STAT4 | Signal transducer and activator of transcription. (748 aa) |
| | IFNA13 | Interferon alpha 13. (195 aa) |
| | GLUD2 | Glutamate dehydrogenase 2, mitochondrial; Important for recycling the chief excitatory neurotransmitter, glutamate, during neurotransmission; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (558 aa) |
| | ENSGGOP00000046758 | Caspase 1; Belongs to the peptidase C14A family. (404 aa) |
| | TNFRSF10A | TNF receptor superfamily member 10a. (468 aa) |
| | FTL | Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. (182 aa) |
| | VPS4A | Uncharacterized protein; Belongs to the AAA ATPase family. (380 aa) |
| | MAPK8 | Mitogen-activated protein kinase. (427 aa) |
| | IFNAR2 | Uncharacterized protein. (519 aa) |
| | MAPK10 | Mitogen-activated protein kinase. (551 aa) |
