Your Input: | |||||
CLDN20 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (219 aa) | ||||
PPP2CA | Serine/threonine-protein phosphatase. (309 aa) | ||||
CLDN17 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (224 aa) | ||||
CDK4 | Cyclin dependent kinase 4; Belongs to the protein kinase superfamily. (303 aa) | ||||
MX2 | MX dynamin like GTPase 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (715 aa) | ||||
MX1 | MX dynamin like GTPase 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (662 aa) | ||||
YWHAQ | 14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (248 aa) | ||||
EIF2S1 | Eukaryotic translation initiation factor 2 subunit alpha. (315 aa) | ||||
PPP2R2B | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (509 aa) | ||||
CASP9 | Caspase 9; Belongs to the peptidase C14A family. (446 aa) | ||||
E2F1 | E2F transcription factor 1. (437 aa) | ||||
MAP2K1 | Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa) | ||||
TRAF3 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (570 aa) | ||||
YWHAB | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta; Belongs to the 14-3-3 family. (246 aa) | ||||
IKBKG | Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (487 aa) | ||||
CLDN19 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (224 aa) | ||||
EGF | Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1183 aa) | ||||
TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (522 aa) | ||||
TYK2 | Tyrosine-protein kinase. (1188 aa) | ||||
IFNG | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (166 aa) | ||||
YWHAH | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta; Belongs to the 14-3-3 family. (246 aa) | ||||
GRB2 | Growth factor receptor bound protein 2. (217 aa) | ||||
PPP2R1A | Protein phosphatase 2 scaffold subunit Aalpha. (589 aa) | ||||
IKBKB | Inhibitor of nuclear factor kappa B kinase subunit beta. (762 aa) | ||||
GSK3B | Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (481 aa) | ||||
CD81 | Tetraspanin. (260 aa) | ||||
AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) | ||||
OAS3 | 2'-5'-oligoadenylate synthetase 3. (1087 aa) | ||||
OAS2 | 2'-5'-oligoadenylate synthetase 2. (687 aa) | ||||
NR1H3 | Nuclear receptor subfamily 1 group H member 3. (453 aa) | ||||
ARAF | A-Raf proto-oncogene, serine/threonine kinase. (606 aa) | ||||
G3R0F2_GORGO | Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa) | ||||
CHUK | IKKbetaNEMObind domain-containing protein. (434 aa) | ||||
PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) | ||||
NFKBIA | NFKB inhibitor alpha. (317 aa) | ||||
PIK3CB | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1041 aa) | ||||
BAX | BCL2 associated X, apoptosis regulator. (217 aa) | ||||
BID | BH3-interacting domain death agonist; Counters the protective effect of Bcl-2. (195 aa) | ||||
CXCL10 | C-X-C motif chemokine. (98 aa) | ||||
RSAD2 | Elp3 domain-containing protein. (361 aa) | ||||
CFLAR | CASP8 and FADD like apoptosis regulator; Belongs to the peptidase C14A family. (480 aa) | ||||
E2F3 | E2F transcription factor 3. (408 aa) | ||||
PPP2R2A | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (457 aa) | ||||
EIF2AK3 | Eukaryotic translation initiation factor 2 alpha kinase 3. (1116 aa) | ||||
TRADD | Death domain-containing protein. (251 aa) | ||||
RIPK1 | Receptor interacting serine/threonine kinase 1. (671 aa) | ||||
PPP2CB | Serine/threonine-protein phosphatase. (309 aa) | ||||
CLDN1 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa) | ||||
CLDN14 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (239 aa) | ||||
IRF9 | Interferon regulatory factor 9. (392 aa) | ||||
EIF2AK1 | Eukaryotic translation initiation factor 2 alpha kinase 1. (630 aa) | ||||
JAK1 | Tyrosine-protein kinase. (1154 aa) | ||||
IFNB1 | Interferon beta 1. (187 aa) | ||||
G3RQE7_GORGO | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) | ||||
MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (454 aa) | ||||
YWHAZ | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta; Belongs to the 14-3-3 family. (245 aa) | ||||
NFKB1 | Nuclear factor kappa B subunit 1. (969 aa) | ||||
CDKN1A | Cyclin dependent kinase inhibitor 1A. (164 aa) | ||||
BAK1 | BCL2 antagonist/killer 1. (211 aa) | ||||
PIK3R3 | Uncharacterized protein. (507 aa) | ||||
EIF2AK2 | Eukaryotic translation initiation factor 2 alpha kinase 2. (551 aa) | ||||
RNASEL | Ribonuclease L. (741 aa) | ||||
IKBKE | Inhibitor of nuclear factor kappa B kinase subunit epsilon. (716 aa) | ||||
FADD | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (208 aa) | ||||
STAT3 | Signal transducer and activator of transcription. (781 aa) | ||||
G3RZ65_GORGO | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (220 aa) | ||||
CASP3 | Caspase 3; Belongs to the peptidase C14A family. (277 aa) | ||||
IFNA2 | Interferon alpha 2. (170 aa) | ||||
MAPK3 | Mitogen-activated protein kinase. (322 aa) | ||||
CLDN3 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (220 aa) | ||||
SOS1 | SOS Ras/Rac guanine nucleotide exchange factor 1. (1333 aa) | ||||
IFIT1B | Interferon induced protein with tetratricopeptide repeats 1B. (473 aa) | ||||
IFIT1 | Interferon induced protein with tetratricopeptide repeats 1. (478 aa) | ||||
DDX58 | DExD/H-box helicase 58. (925 aa) | ||||
CLDN8 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (225 aa) | ||||
EIF2AK4 | Eukaryotic translation initiation factor 2 alpha kinase 4. (1649 aa) | ||||
TBK1 | TANK binding kinase 1. (729 aa) | ||||
FASLG | Fas ligand; Belongs to the tumor necrosis factor family. (280 aa) | ||||
BRAF | B-Raf proto-oncogene, serine/threonine kinase. (768 aa) | ||||
CLDN15 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (228 aa) | ||||
CLDN10 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (228 aa) | ||||
OAS1 | 2'-5'-oligoadenylate synthetase 1. (414 aa) | ||||
STAT1 | Signal transducer and activator of transcription. (777 aa) | ||||
TNFRSF1A | TNF receptor superfamily member 1A. (455 aa) | ||||
FAS | Fas cell surface death receptor. (340 aa) | ||||
RAF1 | Raf-1 proto-oncogene, serine/threonine kinase. (630 aa) | ||||
TLR3 | Toll-like receptor 3 precursor; Belongs to the Toll-like receptor family. (904 aa) | ||||
CLDN22 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (220 aa) | ||||
RELA | RELA proto-oncogene, NF-kB subunit. (551 aa) | ||||
CLDN7 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa) | ||||
CYCS | Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain (By similarity). (105 aa) | ||||
CLDN16 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (305 aa) | ||||
PIAS1 | Protein inhibitor of activated STAT 1. (653 aa) | ||||
CLDN2 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (230 aa) | ||||
TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (403 aa) | ||||
ENSGGOP00000032596 | CCHC NOA-type domain-containing protein. (417 aa) | ||||
CCND1 | Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (295 aa) | ||||
NRAS | NRAS proto-oncogene, GTPase. (189 aa) | ||||
AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) | ||||
SOCS3 | Suppressor of cytokine signaling 3. (225 aa) | ||||
IFNAR1 | Interferon alpha and beta receptor subunit 1. (558 aa) | ||||
APAF1 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1248 aa) | ||||
ENSGGOP00000035522 | Interferon alpha 1. (198 aa) | ||||
EIF3E | Eukaryotic translation initiation factor 3 subunit E; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (457 aa) | ||||
LDLR | Low density lipoprotein receptor. (859 aa) | ||||
HRAS | HRas proto-oncogene, GTPase. (189 aa) | ||||
BAD | BCL2 associated agonist of cell death. (168 aa) | ||||
MAPK1 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa) | ||||
YWHAE | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon; Belongs to the 14-3-3 family. (255 aa) | ||||
PPARA | Peroxisome proliferator activated receptor alpha. (468 aa) | ||||
EGFR | Receptor protein-tyrosine kinase. (1205 aa) | ||||
CLDN9 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (217 aa) | ||||
RXRA | Retinoid X receptor alpha. (463 aa) | ||||
PSME3 | Proteasome activator subunit 3. (265 aa) | ||||
IRF7 | Interferon regulatory factor 7. (516 aa) | ||||
PPP2R2C | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (534 aa) | ||||
CLDN4 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (209 aa) | ||||
IFNA13 | Interferon alpha 13. (195 aa) | ||||
YWHAG | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma; Belongs to the 14-3-3 family. (250 aa) | ||||
SCARB1 | Scavenger receptor class B member 1; Belongs to the CD36 family. (509 aa) | ||||
CLDN11 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (207 aa) | ||||
SOS2 | SOS Ras/Rho guanine nucleotide exchange factor 2. (1331 aa) | ||||
CTNNB1 | Catenin beta 1. (781 aa) | ||||
ENSGGOP00000049412 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (117 aa) | ||||
PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (723 aa) | ||||
IFNAR2 | Uncharacterized protein. (519 aa) |