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| | CALM3 | Calmodulin 1; Belongs to the calmodulin family. (149 aa) |
| | CX3CL1 | C-X3-C motif chemokine ligand 1. (397 aa) |
| | ADCY9 | Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1353 aa) |
| | PLCB2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1185 aa) |
| | AKAP13 | A-kinase anchoring protein 13. (2817 aa) |
| | IL6R | Interleukin 6 receptor. (468 aa) |
| | CDK4 | Cyclin dependent kinase 4; Belongs to the protein kinase superfamily. (303 aa) |
| | CASP9 | Caspase 9; Belongs to the peptidase C14A family. (446 aa) |
| | ADCY6 | Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1168 aa) |
| | GNB3 | G protein subunit beta 3. (340 aa) |
| | GNAS | GNAS complex locus. (985 aa) |
| | GNG3 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa) |
| | IL1R1 | Interleukin 1 receptor type 1. (569 aa) |
| | E2F1 | E2F transcription factor 1. (437 aa) |
| | MAP2K1 | Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa) |
| | MAPK13 | Mitogen-activated protein kinase. (365 aa) |
| | ADCY3 | Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1145 aa) |
| | CREB3L2 | cAMP responsive element binding protein 3 like 2. (520 aa) |
| | ADCY4 | Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1077 aa) |
| | IKBKG | Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (487 aa) |
| | ROCK2 | Uncharacterized protein; Belongs to the protein kinase superfamily. (460 aa) |
| | ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1. (2706 aa) |
| | CREB3L4 | cAMP responsive element binding protein 3 like 4. (395 aa) |
| | CCL4 | C-C motif chemokine. (92 aa) |
| | GRB2 | Growth factor receptor bound protein 2. (217 aa) |
| | IL1B | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (269 aa) |
| | TAPBP | TAP binding protein. (504 aa) |
| | IKBKB | Inhibitor of nuclear factor kappa B kinase subunit beta. (762 aa) |
| | CCL3L1 | C-C motif chemokine. (93 aa) |
| | CREB3 | cAMP responsive element binding protein 3. (371 aa) |
| | GSK3B | Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (481 aa) |
| | PTGER4 | Prostaglandin E receptor 4; Belongs to the G-protein coupled receptor 1 family. (490 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) |
| | ITGB3 | Integrin beta; Belongs to the integrin beta chain family. (837 aa) |
| | GNG4 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa) |
| | G3QYA4_GORGO | Major histocompatibility complex, class I, G; Belongs to the MHC class I family. (350 aa) |
| | GNAI1 | G protein subunit alpha i1. (354 aa) |
| | ELK1 | ETS transcription factor ELK1. (452 aa) |
| | NFATC4 | Nuclear factor of activated T cells 4. (920 aa) |
| | G3R0F2_GORGO | Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa) |
| | CHUK | IKKbetaNEMObind domain-containing protein. (434 aa) |
| | CXCR2 | C-X-C chemokine receptor type 2; Receptor for interleukin-8 which is a powerful neutrophil chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Binds to IL-8 with high affinity. Also binds with high affinity to CXCL3, GRO/MGSA and NAP-2 (By similarity). (360 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) |
| | NFKBIA | NFKB inhibitor alpha. (317 aa) |
| | GNA12 | G protein subunit alpha 12. (381 aa) |
| | ROCK1 | Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1354 aa) |
| | PIK3CB | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1041 aa) |
| | RPS6KB2 | Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (482 aa) |
| | GNA13 | G protein subunit alpha 13. (377 aa) |
| | G3R3J7_GORGO | MHC_I-like_Ag-recog domain-containing protein. (187 aa) |
| | ATF4 | Activating transcription factor 4. (351 aa) |
| | BAX | BCL2 associated X, apoptosis regulator. (217 aa) |
| | BID | BH3-interacting domain death agonist; Counters the protective effect of Bcl-2. (195 aa) |
| | RAC2 | Rac family small GTPase 2. (192 aa) |
| | PDGFRA | Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1089 aa) |
| | MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2520 aa) |
| | CCR3 | C-C motif chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family. (376 aa) |
| | TAP1 | Antigen peptide transporter 1; Involved in the transport of antigens from the cytoplasm to the endoplasmic reticulum for association with MHC class I molecules. Also acts as a molecular scaffold for the final stage of MHC class I folding, namely the binding of peptide. Nascent MHC class I molecules associate with TAP via tapasin (By similarity); Belongs to the ABC transporter superfamily. ABCB family. MHC peptide exporter (TC 3.A.1.209) subfamily. (808 aa) |
| | PRKCB | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa) |
| | E2F3 | E2F transcription factor 3. (408 aa) |
| | ADCY2 | Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1021 aa) |
| | TRADD | Death domain-containing protein. (251 aa) |
| | PTGER2 | Prostaglandin E receptor 2; Belongs to the G-protein coupled receptor 1 family. (358 aa) |
| | PLCB3 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1234 aa) |
| | IL10RB | Interleukin 10 receptor subunit beta. (325 aa) |
| | RIPK1 | Receptor interacting serine/threonine kinase 1. (671 aa) |
| | TRAF5 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (557 aa) |
| | G3RAL4_GORGO | Major histocompatibility complex, class I, E; Belongs to the MHC class I family. (354 aa) |
| | RHOA | Uncharacterized protein. (179 aa) |
| | MAPK12 | Mitogen-activated protein kinase. (312 aa) |
| | RHEB | Ras homolog, mTORC1 binding. (184 aa) |
| | GNG11 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa) |
| | GNA11 | Uncharacterized protein. (313 aa) |
| | GNGT1 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa) |
| | CREB3L1 | cAMP responsive element binding protein 3 like 1. (519 aa) |
| | ARHGEF1 | Rho guanine nucleotide exchange factor 1. (948 aa) |
| | PTK2B | Protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa) |
| | PRKCA | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa) |
| | CALR | Calreticulin. (417 aa) |
| | STING1 | Transmembrane protein 173. (379 aa) |
| | CCL2 | C-C motif chemokine. (99 aa) |
| | CXCL12 | C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family. (140 aa) |
| | JAK1 | Tyrosine-protein kinase. (1154 aa) |
| | IFNB1 | Interferon beta 1. (187 aa) |
| | PTGS2 | Prostaglandin-endoperoxide synthase 2. (604 aa) |
| | G3RQE7_GORGO | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | SRC | Tyrosine-protein kinase. (542 aa) |
| | IL6 | Interleukin 6. (234 aa) |
| | MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (454 aa) |
| | NFKB1 | Nuclear factor kappa B subunit 1. (969 aa) |
| | CDKN1A | Cyclin dependent kinase inhibitor 1A. (164 aa) |
| | BAK1 | BCL2 antagonist/killer 1. (211 aa) |
| | RPS6KB1 | Protein kinase domain-containing protein. (210 aa) |
| | PIK3R3 | Uncharacterized protein. (507 aa) |
| | TSC2 | TSC complex subunit 2. (1806 aa) |
| | FADD | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (208 aa) |
| | CCL3 | C-C motif chemokine. (92 aa) |
| | STAT3 | Signal transducer and activator of transcription. (781 aa) |
| | IL10RA | Interleukin 10 receptor subunit alpha. (578 aa) |
| | CASP3 | Caspase 3; Belongs to the peptidase C14A family. (277 aa) |
| | ADCY5 | Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1257 aa) |
| | IFNA2 | Interferon alpha 2. (170 aa) |
| | PTK2 | Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1096 aa) |
| | MAPK3 | Mitogen-activated protein kinase. (322 aa) |
| | SOS1 | SOS Ras/Rac guanine nucleotide exchange factor 1. (1333 aa) |
| | MAPK11 | Mitogen-activated protein kinase. (325 aa) |
| | PTGER1 | Prostaglandin E receptor 1. (402 aa) |
| | TBK1 | TANK binding kinase 1. (729 aa) |
| | MAP2K6 | Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (335 aa) |
| | FASLG | Fas ligand; Belongs to the tumor necrosis factor family. (280 aa) |
| | CXCL8 | Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (99 aa) |
| | ITPR3 | Inositol 1,4,5-trisphosphate receptor type 3. (2677 aa) |
| | GNB4 | G protein subunit beta 4. (340 aa) |
| | PDIA3 | Protein disulfide-isomerase. (383 aa) |
| | CGAS | Cyclic GMP-AMP synthase. (447 aa) |
| | PRKACB | Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa) |
| | GNAI3 | G protein subunit alpha i3. (354 aa) |
| | ARHGEF11 | Rho guanine nucleotide exchange factor 11. (1562 aa) |
| | B2M | Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity). (119 aa) |
| | TNFRSF1A | TNF receptor superfamily member 1A. (455 aa) |
| | FAS | Fas cell surface death receptor. (340 aa) |
| | RAF1 | Raf-1 proto-oncogene, serine/threonine kinase. (630 aa) |
| | PPP3CB | Serine/threonine-protein phosphatase. (524 aa) |
| | RELA | RELA proto-oncogene, NF-kB subunit. (551 aa) |
| | TSC1 | TSC complex subunit 1. (1164 aa) |
| | CYCS | Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain (By similarity). (105 aa) |
| | GNG2 | G protein gamma domain-containing protein. (41 aa) |
| | ADCY7 | Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1083 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (403 aa) |
| | CDKN2A | Cyclin dependent kinase inhibitor 2A. (167 aa) |
| | GNG12 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa) |
| | ATF2 | Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa) |
| | ENSGGOP00000032065 | Uncharacterized protein. (245 aa) |
| | PLCB4 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1204 aa) |
| | ENSGGOP00000032596 | CCHC NOA-type domain-containing protein. (417 aa) |
| | CCND1 | Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (295 aa) |
| | NRAS | NRAS proto-oncogene, GTPase. (189 aa) |
| | AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) |
| | PPP3CA | Serine/threonine-protein phosphatase. (521 aa) |
| | ENSGGOP00000034747 | Cyclic AMP-responsive element-binding protein 5; Binds to the cAMP response element and activates transcription. (508 aa) |
| | PRKCG | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (698 aa) |
| | GNB1 | G protein subunit beta 1. (340 aa) |
| | ENSGGOP00000035522 | Interferon alpha 1. (198 aa) |
| | ATF6B | Activating transcription factor 6 beta. (703 aa) |
| | CRKL | Uncharacterized protein. (201 aa) |
| | GNG13 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (67 aa) |
| | HRAS | HRas proto-oncogene, GTPase. (189 aa) |
| | ITPR2 | Inositol 1,4,5-trisphosphate receptor type 2. (2714 aa) |
| | PPP3R1 | Uncharacterized protein. (189 aa) |
| | GNB2 | G protein subunit beta 2. (340 aa) |
| | MAPK1 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa) |
| | EGFR | Receptor protein-tyrosine kinase. (1205 aa) |
| | CALML3 | Calmodulin like 3; Belongs to the calmodulin family. (149 aa) |
| | NFATC2 | Nuclear factor of activated T cells 2. (925 aa) |
| | ENSGGOP00000042576 | Uncharacterized protein. (348 aa) |
| | ITGAV | Integrin subunit alpha V; Belongs to the integrin alpha chain family. (1002 aa) |
| | PLCB1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa) |
| | ENSGGOP00000043747 | Uncharacterized protein. (157 aa) |
| | ENSGGOP00000044877 | Uncharacterized protein; Belongs to the calmodulin family. (123 aa) |
| | GNGT2 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (88 aa) |
| | IFNA13 | Interferon alpha 13. (195 aa) |
| | GNG7 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa) |
| | TAP2 | Transporter 2, ATP binding cassette subfamily B member. (724 aa) |
| | ARHGEF12 | Rho guanine nucleotide exchange factor 12. (1504 aa) |
| | SOS2 | SOS Ras/Rho guanine nucleotide exchange factor 2. (1331 aa) |
| | CTNNB1 | Catenin beta 1. (781 aa) |
| | CALML4 | Uncharacterized protein. (196 aa) |
| | ENSGGOP00000049412 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (117 aa) |
| | CCR1 | C-C motif chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family. (355 aa) |
| | ADCY8 | Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1251 aa) |
| | PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (723 aa) |
| | CXCR4 | C-X-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family. (423 aa) |
| | PTGER3 | Prostaglandin E receptor 3. (418 aa) |
| | CCR5 | C-C chemokine receptor type 5; Receptor for a number of inflammatory CC-chemokines including MIP-1-alpha, MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation (By similarity). (352 aa) |
| | NFATC1 | Nuclear factor of activated T cells 1. (948 aa) |
| | BCAR1 | BCAR1 scaffold protein, Cas family member. (916 aa) |
