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CALM3 | Calmodulin 1; Belongs to the calmodulin family. (149 aa) | ||||
FOS | Fos proto-oncogene, AP-1 transcription factor subunit. (380 aa) | ||||
CSF2 | Colony stimulating factor 2. (144 aa) | ||||
UBC | Polyubiquitin-C; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair [...] (315 aa) | ||||
CDK4 | Cyclin dependent kinase 4; Belongs to the protein kinase superfamily. (303 aa) | ||||
BECN1 | Beclin 1. (450 aa) | ||||
CD200R1L | CD200 receptor 1 like. (271 aa) | ||||
CASP9 | Caspase 9; Belongs to the peptidase C14A family. (446 aa) | ||||
GNB3 | G protein subunit beta 3. (340 aa) | ||||
PIK3R5 | Phosphoinositide-3-kinase regulatory subunit 5. (881 aa) | ||||
GNG3 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa) | ||||
CXCL1 | C-X-C motif chemokine. (107 aa) | ||||
E2F1 | E2F transcription factor 1. (437 aa) | ||||
MAP2K1 | Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa) | ||||
IL6ST | Fibronectin type-III domain-containing protein. (329 aa) | ||||
MAPK13 | Mitogen-activated protein kinase. (365 aa) | ||||
TRAF3 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (570 aa) | ||||
UBA52 | Ubiquitin-like domain-containing protein. (233 aa) | ||||
IKBKG | Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (487 aa) | ||||
CD200R1 | CD200 receptor 1. (348 aa) | ||||
ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1. (2706 aa) | ||||
TYK2 | Tyrosine-protein kinase. (1188 aa) | ||||
CREBBP | CREB binding protein. (2436 aa) | ||||
CCR8 | C-C motif chemokine receptor 8; Belongs to the G-protein coupled receptor 1 family. (355 aa) | ||||
ATG3 | Autophagy-related protein 3. (314 aa) | ||||
IKBKB | Inhibitor of nuclear factor kappa B kinase subunit beta. (762 aa) | ||||
GSK3B | Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (481 aa) | ||||
RPS27A | Ubiquitin-like domain-containing protein. (156 aa) | ||||
AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) | ||||
PLCG1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1290 aa) | ||||
GNG4 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa) | ||||
G3QYA4_GORGO | Major histocompatibility complex, class I, G; Belongs to the MHC class I family. (350 aa) | ||||
BECN2 | Beclin 2. (431 aa) | ||||
EP300 | E1A binding protein p300. (2416 aa) | ||||
IFNGR1 | Interferon gamma receptor 1. (489 aa) | ||||
TCF7L1 | Transcription factor 7 like 1. (587 aa) | ||||
CD86 | CD86 molecule. (329 aa) | ||||
NFATC4 | Nuclear factor of activated T cells 4. (920 aa) | ||||
G3R0F2_GORGO | Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa) | ||||
CHUK | IKKbetaNEMObind domain-containing protein. (434 aa) | ||||
PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) | ||||
NFKBIA | NFKB inhibitor alpha. (317 aa) | ||||
PIK3CB | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1041 aa) | ||||
ANGPT2 | Angiopoietin 2. (496 aa) | ||||
G3R3J7_GORGO | MHC_I-like_Ag-recog domain-containing protein. (187 aa) | ||||
BAX | BCL2 associated X, apoptosis regulator. (217 aa) | ||||
SYK | Tyrosine-protein kinase. (635 aa) | ||||
BID | BH3-interacting domain death agonist; Counters the protective effect of Bcl-2. (195 aa) | ||||
MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2520 aa) | ||||
CCR3 | C-C motif chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family. (376 aa) | ||||
E2F3 | E2F transcription factor 3. (408 aa) | ||||
TRADD | Death domain-containing protein. (251 aa) | ||||
GABARAPL2 | GABA type A receptor associated protein like 2. (117 aa) | ||||
LYN | Tyrosine-protein kinase. (512 aa) | ||||
G3RAL4_GORGO | Major histocompatibility complex, class I, E; Belongs to the MHC class I family. (354 aa) | ||||
CCR4 | C-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family. (360 aa) | ||||
GABARAP | GABA type A receptor-associated protein. (117 aa) | ||||
CLEC2B | C-type lectin domain family 2 member B. (149 aa) | ||||
ZFP36 | ZFP36 ring finger protein. (332 aa) | ||||
MAPK12 | Mitogen-activated protein kinase. (312 aa) | ||||
GNG11 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa) | ||||
GNGT1 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa) | ||||
PDGFB | Platelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (220 aa) | ||||
IRF9 | Interferon regulatory factor 9. (392 aa) | ||||
JAK1 | Tyrosine-protein kinase. (1154 aa) | ||||
IFNB1 | Interferon beta 1. (187 aa) | ||||
GABARAPL1 | Uncharacterized protein. (117 aa) | ||||
PTGS2 | Prostaglandin-endoperoxide synthase 2. (604 aa) | ||||
G3RQE7_GORGO | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) | ||||
SRC | Tyrosine-protein kinase. (542 aa) | ||||
IL6 | Interleukin 6. (234 aa) | ||||
MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (454 aa) | ||||
NFKB1 | Nuclear factor kappa B subunit 1. (969 aa) | ||||
CDKN1A | Cyclin dependent kinase inhibitor 1A. (164 aa) | ||||
BAK1 | BCL2 antagonist/killer 1. (211 aa) | ||||
PIK3R3 | Uncharacterized protein. (507 aa) | ||||
EIF2AK2 | Eukaryotic translation initiation factor 2 alpha kinase 2. (551 aa) | ||||
IKBKE | Inhibitor of nuclear factor kappa B kinase subunit epsilon. (716 aa) | ||||
FADD | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (208 aa) | ||||
STAT3 | Signal transducer and activator of transcription. (781 aa) | ||||
CASP3 | Caspase 3; Belongs to the peptidase C14A family. (277 aa) | ||||
IFNA2 | Interferon alpha 2. (170 aa) | ||||
MAPK3 | Mitogen-activated protein kinase. (322 aa) | ||||
CXCL3 | C-X-C motif chemokine. (107 aa) | ||||
MAPK11 | Mitogen-activated protein kinase. (325 aa) | ||||
MAPK9 | Mitogen-activated protein kinase. (424 aa) | ||||
PIK3CG | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma; Belongs to the PI3/PI4-kinase family. (1102 aa) | ||||
TBK1 | TANK binding kinase 1. (729 aa) | ||||
MAP2K6 | Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (335 aa) | ||||
C3 | Complement C3. (1663 aa) | ||||
CXCL8 | Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (99 aa) | ||||
ITPR3 | Inositol 1,4,5-trisphosphate receptor type 3. (2677 aa) | ||||
GNB4 | G protein subunit beta 4. (340 aa) | ||||
G3SET6_GORGO | C-X-C motif chemokine. (107 aa) | ||||
STAT1 | Signal transducer and activator of transcription. (777 aa) | ||||
TNFRSF1A | TNF receptor superfamily member 1A. (455 aa) | ||||
FAS | Fas cell surface death receptor. (340 aa) | ||||
RAF1 | Raf-1 proto-oncogene, serine/threonine kinase. (630 aa) | ||||
PPP3CB | Serine/threonine-protein phosphatase. (524 aa) | ||||
TLR3 | Toll-like receptor 3 precursor; Belongs to the Toll-like receptor family. (904 aa) | ||||
RELA | RELA proto-oncogene, NF-kB subunit. (551 aa) | ||||
PLCG2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa) | ||||
HCK | Tyrosine-protein kinase. (526 aa) | ||||
HIF1A | Hypoxia inducible factor 1 subunit alpha. (850 aa) | ||||
CYCS | Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain (By similarity). (105 aa) | ||||
GNG2 | G protein gamma domain-containing protein. (41 aa) | ||||
TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (403 aa) | ||||
GNG12 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa) | ||||
TCF7 | HMG box domain-containing protein. (300 aa) | ||||
ENSGGOP00000032596 | CCHC NOA-type domain-containing protein. (417 aa) | ||||
CCND1 | Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (295 aa) | ||||
NRAS | NRAS proto-oncogene, GTPase. (189 aa) | ||||
AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) | ||||
PPP3CA | Serine/threonine-protein phosphatase. (521 aa) | ||||
FGF2 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (258 aa) | ||||
RCAN1 | Regulator of calcineurin 1. (276 aa) | ||||
IFNAR1 | Interferon alpha and beta receptor subunit 1. (558 aa) | ||||
GNB1 | G protein subunit beta 1. (340 aa) | ||||
ENSGGOP00000035522 | Interferon alpha 1. (198 aa) | ||||
PIK3C3 | Phosphatidylinositol 3-kinase catalytic subunit type 3. (916 aa) | ||||
PREX1 | Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1. (1658 aa) | ||||
ICAM1 | Intercellular adhesion molecule 1; ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation (By similarity). Belongs to the immunoglobulin superfamily. ICAM family. (532 aa) | ||||
MAPKAPK2 | Protein kinase domain-containing protein. (374 aa) | ||||
GNG13 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (67 aa) | ||||
HRAS | HRas proto-oncogene, GTPase. (189 aa) | ||||
ITPR2 | Inositol 1,4,5-trisphosphate receptor type 2. (2714 aa) | ||||
PPP3R1 | Uncharacterized protein. (189 aa) | ||||
ENSGGOP00000040207 | Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. (400 aa) | ||||
GNB2 | G protein subunit beta 2. (340 aa) | ||||
MAPK1 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa) | ||||
MAP2K7 | Mitogen-activated protein kinase kinase 7. (435 aa) | ||||
TCF7L2 | HMG box domain-containing protein. (296 aa) | ||||
CALML3 | Calmodulin like 3; Belongs to the calmodulin family. (149 aa) | ||||
NFATC2 | Nuclear factor of activated T cells 2. (925 aa) | ||||
IRF7 | Interferon regulatory factor 7. (516 aa) | ||||
ENSGGOP00000044877 | Uncharacterized protein; Belongs to the calmodulin family. (123 aa) | ||||
GNGT2 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (88 aa) | ||||
IFNA13 | Interferon alpha 13. (195 aa) | ||||
GNG7 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa) | ||||
ATG14 | Autophagy related 14. (492 aa) | ||||
CTNNB1 | Catenin beta 1. (781 aa) | ||||
CALML4 | Uncharacterized protein. (196 aa) | ||||
MAPK8 | Mitogen-activated protein kinase. (427 aa) | ||||
ENSGGOP00000049412 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (117 aa) | ||||
CCR1 | C-C motif chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family. (355 aa) | ||||
PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (723 aa) | ||||
IFNAR2 | Uncharacterized protein. (519 aa) | ||||
ENSGGOP00000051131 | Uncharacterized protein. (126 aa) | ||||
MAPK10 | Mitogen-activated protein kinase. (551 aa) | ||||
CCR5 | C-C chemokine receptor type 5; Receptor for a number of inflammatory CC-chemokines including MIP-1-alpha, MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation (By similarity). (352 aa) | ||||
NFATC1 | Nuclear factor of activated T cells 1. (948 aa) |