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ETV4 | ETS variant 4. (484 aa) | ||||
ZBTB16 | Zinc finger and BTB domain containing 16. (673 aa) | ||||
FLT3 | Fms related tyrosine kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (993 aa) | ||||
KMT2A | Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. TRX/MLL subfamily. (3982 aa) | ||||
CSF2 | Colony stimulating factor 2. (144 aa) | ||||
IL3 | Interleukin-3; Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. Belongs to the IL-3 family. (152 aa) | ||||
SIX1 | Homeobox protein SIX1; Transcription factor that is involved in the regulation of cell proliferation, apoptosis and embryonic development. Plays an important role in the development of several organs, including kidney, muscle and inner ear. Depending on context, functions as transcriptional repressor or activator. Lacks an activation domain, and requires interaction with EYA family members for transcription activation. Mediates nuclear translocation of EYA1 and EYA2. Binds the 5'-TCA[AG][AG]TTNC-3' motif present in the MEF3 element in the MYOG promoter. Regulates the expression of nume [...] (284 aa) | ||||
ETV6 | ETS variant 6. (452 aa) | ||||
IGFBP3 | Insulin like growth factor binding protein 3. (291 aa) | ||||
ETV5 | ETS variant 5. (510 aa) | ||||
DDIT3 | DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (169 aa) | ||||
LDB1 | LIM domain binding 1. (411 aa) | ||||
CCNA2 | Cyclin A2; Belongs to the cyclin family. (432 aa) | ||||
HOXA9 | Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. (272 aa) | ||||
IL2RB | Interleukin 2 receptor subunit beta. (551 aa) | ||||
TRAF1 | TNF receptor-associated factor. (416 aa) | ||||
MEN1 | Menin 1. (615 aa) | ||||
RARA | Uncharacterized protein. (624 aa) | ||||
EYA1 | Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (592 aa) | ||||
PAX5 | Paired box 5. (396 aa) | ||||
ITGAM | Integrin subunit alpha M; Belongs to the integrin alpha chain family. (1152 aa) | ||||
PAX7 | Paired box 7. (520 aa) | ||||
DEFA1B | DEFENSIN domain-containing protein. (94 aa) | ||||
PER2 | Period circadian regulator 2. (1255 aa) | ||||
KLF3 | Kruppel like factor 3. (345 aa) | ||||
TMPRSS2 | Transmembrane serine protease 2; Belongs to the peptidase S1 family. (529 aa) | ||||
IGF1 | IlGF domain-containing protein. (196 aa) | ||||
GADD45G | Growth arrest and DNA damage inducible gamma. (159 aa) | ||||
MYCN | MYCN proto-oncogene, bHLH transcription factor. (464 aa) | ||||
HDAC2 | Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (488 aa) | ||||
BIRC3 | Baculoviral IAP repeat containing 3. (604 aa) | ||||
SPI1 | Spi-1 proto-oncogene. (271 aa) | ||||
DOT1L | Histone-lysine N-methyltransferase, H3 lysine-79 specific. (1537 aa) | ||||
SLC45A3 | Solute carrier family 45 member 3. (553 aa) | ||||
SPINT1 | Serine peptidase inhibitor, Kunitz type 1. (529 aa) | ||||
CEBPE | CCAAT/enhancer-binding protein. (281 aa) | ||||
FOXO1 | Forkhead box O1. (655 aa) | ||||
BIRC2 | Baculoviral IAP repeat containing 2. (618 aa) | ||||
NGFR | Nerve growth factor receptor. (427 aa) | ||||
CD86 | CD86 molecule. (329 aa) | ||||
FLT1 | Fms related tyrosine kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1302 aa) | ||||
FUT8 | Alpha-(1,6)-fucosyltransferase; Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans. Belongs to the glycosyltransferase 23 family. (575 aa) | ||||
PBX3 | Homeobox domain-containing protein. (450 aa) | ||||
CCND2 | Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (289 aa) | ||||
GRIA3 | Glutamate ionotropic receptor AMPA type subunit 3. (894 aa) | ||||
RXRB | Retinoid X receptor beta. (537 aa) | ||||
HPGD | 15-hydroxyprostaglandin dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (266 aa) | ||||
JUP | Junction plakoglobin. (745 aa) | ||||
MMP3 | Matrix metallopeptidase 3. (477 aa) | ||||
BAX | BCL2 associated X, apoptosis regulator. (217 aa) | ||||
CD14 | Monocyte differentiation antigen CD14; Coreceptor for bacterial lipopolysaccharide. In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell su [...] (375 aa) | ||||
ATM | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3023 aa) | ||||
GADD45A | Growth arrest and DNA damage inducible alpha. (165 aa) | ||||
FEV | FEV transcription factor, ETS family member. (238 aa) | ||||
MLLT1 | MLLT1 super elongation complex subunit. (556 aa) | ||||
DEFA4 | Defensin alpha 4. (97 aa) | ||||
DEFA6 | Defensin alpha 6. (100 aa) | ||||
CDK9 | Cyclin dependent kinase 9; Belongs to the protein kinase superfamily. (372 aa) | ||||
PBX1 | PBX homeobox 1. (430 aa) | ||||
IL1R2 | Interleukin 1 receptor type 2. (398 aa) | ||||
HDAC1 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (482 aa) | ||||
ZBTB17 | Zinc finger and BTB domain containing 17. (800 aa) | ||||
IGF1R | Tyrosine-protein kinase receptor. (1367 aa) | ||||
G3RB29_GORGO | Granzyme B; Belongs to the peptidase S1 family. (247 aa) | ||||
MMP9 | Matrix metallopeptidase 9. (707 aa) | ||||
PRCC | Proline rich mitotic checkpoint control factor. (491 aa) | ||||
NSD2 | Nuclear receptor binding SET domain protein 2. (1365 aa) | ||||
PLAU | Plasminogen activator, urokinase. (431 aa) | ||||
PAX3 | Paired box 3. (486 aa) | ||||
JMJD1C | Jumonji domain containing 1C. (2451 aa) | ||||
DEFA5 | Defensin alpha 5. (94 aa) | ||||
WNT16 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa) | ||||
TGFBR2 | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa) | ||||
CDKN2C | Cyclin dependent kinase inhibitor 2C. (168 aa) | ||||
CSF1R | Colony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (972 aa) | ||||
AFF1 | AF4/FMR2 family member 1. (1219 aa) | ||||
FUS | FUS RNA binding protein. (523 aa) | ||||
G3RQR5_GORGO | Ig-like domain-containing protein. (117 aa) | ||||
IL6 | Interleukin 6. (234 aa) | ||||
MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (454 aa) | ||||
BCL11B | BAF chromatin remodeling complex subunit BCL11B. (894 aa) | ||||
NFKB1 | Nuclear factor kappa B subunit 1. (969 aa) | ||||
CDKN1A | Cyclin dependent kinase inhibitor 1A. (164 aa) | ||||
BAK1 | BCL2 antagonist/killer 1. (211 aa) | ||||
G3RSZ1_GORGO | KRAB-related domain-containing protein. (188 aa) | ||||
ELK4 | ETS transcription factor ELK4. (431 aa) | ||||
BCL2L1 | BCL2 like 1. (233 aa) | ||||
H3C13 | Histone H3; Belongs to the histone H3 family. (136 aa) | ||||
NFKBIZ | NFKB inhibitor zeta. (718 aa) | ||||
PTK2 | Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1096 aa) | ||||
GADD45B | Growth arrest and DNA damage inducible beta. (160 aa) | ||||
TLX1 | T cell leukemia homeobox 1. (335 aa) | ||||
PROM1 | Prominin 1. (865 aa) | ||||
RXRG | Retinoid X receptor gamma. (463 aa) | ||||
CD40 | CD40 molecule. (277 aa) | ||||
LYL1 | LYL1 basic helix-loop-helix family member. (280 aa) | ||||
CXCL8 | Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (99 aa) | ||||
SMAD1 | Mothers against decapentaplegic homolog. (465 aa) | ||||
DUSP6 | Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (381 aa) | ||||
CCNA1 | Cyclin A1; Belongs to the cyclin family. (465 aa) | ||||
ZEB1 | Zinc finger E-box binding homeobox 1. (1108 aa) | ||||
H3-3A | Histone H3; Belongs to the histone H3 family. (136 aa) | ||||
BMP2K | BMP2 inducible kinase. (1153 aa) | ||||
BMI1 | RING-type domain-containing protein. (326 aa) | ||||
RELA | RELA proto-oncogene, NF-kB subunit. (551 aa) | ||||
HOXA11 | Homeobox A11. (315 aa) | ||||
HHEX | Homeobox domain-containing protein. (98 aa) | ||||
PAX8 | Paired domain-containing protein. (457 aa) | ||||
G3SCC9_GORGO | Histone H3; Belongs to the histone H3 family. (136 aa) | ||||
TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (403 aa) | ||||
ITGB7 | Integrin beta; Belongs to the integrin beta chain family. (802 aa) | ||||
CCNT2 | Cyclin T2; Belongs to the cyclin family. (730 aa) | ||||
MAX | MYC associated factor X. (148 aa) | ||||
PPARG | Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (505 aa) | ||||
WT1 | Uncharacterized protein. (516 aa) | ||||
BCL6 | BCL6 transcription repressor. (706 aa) | ||||
HOXA10 | Homeobox A10. (414 aa) | ||||
MEIS1 | Homeobox domain-containing protein. (463 aa) | ||||
RUNX1 | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (480 aa) | ||||
FCGR1A | Uncharacterized protein. (374 aa) | ||||
BCL2A1 | BCL2 related protein A1. (196 aa) | ||||
SIN3A | Uncharacterized protein. (154 aa) | ||||
LMO2 | LIM domain only 2. (222 aa) | ||||
TFE3 | Transcription factor binding to IGHM enhancer 3. (575 aa) | ||||
BAIAP3 | BAI1 associated protein 3. (1187 aa) | ||||
CEBPA | BZIP domain-containing protein. (141 aa) | ||||
PDGFA | PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (234 aa) | ||||
SS18 | SS18 subunit of BAF chromatin remodeling complex. (418 aa) | ||||
MITF | Melanocyte inducing transcription factor. (526 aa) | ||||
HMGA2 | High mobility group AT-hook 2. (147 aa) | ||||
NTRK1 | Tyrosine-protein kinase receptor. (796 aa) | ||||
RXRA | Retinoid X receptor alpha. (463 aa) | ||||
MET | Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] (1409 aa) | ||||
CEBPB | CCAAT/enhancer-binding protein. (345 aa) | ||||
ERG | ETS transcription factor ERG. (486 aa) | ||||
ATF1 | Activating transcription factor 1. (270 aa) | ||||
FLI1 | Fli-1 proto-oncogene, ETS transcription factor. (452 aa) | ||||
POLK | DNA polymerase kappa. (897 aa) | ||||
DDX5 | DEAD-box helicase 5; Belongs to the DEAD box helicase family. (614 aa) | ||||
NUPR1 | Nuclear protein 1, transcriptional regulator. (82 aa) | ||||
MPO | Myeloperoxidase. (747 aa) | ||||
DDB2 | Damage specific DNA binding protein 2. (430 aa) | ||||
CDKN1B | Uncharacterized protein. (205 aa) | ||||
ARNT2 | Uncharacterized protein. (759 aa) | ||||
RUNX2 | Runt domain-containing protein. (541 aa) | ||||
RUNX1T1 | RUNX1 partner transcriptional co-repressor 1. (663 aa) | ||||
CDK14 | Cyclin dependent kinase 14; Belongs to the protein kinase superfamily. (469 aa) |