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ABAT ABAT OXCT1 OXCT1 ALDH1B1 ALDH1B1 ACSL5 ACSL5 HSDL2 HSDL2 LOC100994494 LOC100994494 ACAD8 ACAD8 ACOX3 ACOX3 CRAT CRAT AACS AACS ACADS ACADS CPT1B CPT1B HPDL HPDL CPT1A CPT1A ACYP1 ACYP1 ACSS1 ACSS1 ECH1 ECH1 DIP2B DIP2B ACSL3 ACSL3 IVD IVD ACYP2 ACYP2 ACOX2 ACOX2 ALDH6A1 ALDH6A1 AASDHPPT AASDHPPT ENSPPAP00000015849 ENSPPAP00000015849 ACSM4 ACSM4 HMGCLL1 HMGCLL1 AASDH AASDH ENSPPAP00000017735 ENSPPAP00000017735 ACSL4 ACSL4 HSD17B8 HSD17B8 ENSPPAP00000018575 ENSPPAP00000018575 ACBD7 ACBD7 OXSM OXSM SCP2D1 SCP2D1 ACSBG1 ACSBG1 HMGCS2 HMGCS2 BDH1 BDH1 ECHDC2 ECHDC2 ETFDH ETFDH ACACB ACACB SIRT3 SIRT3 HADH HADH LOC100973698 LOC100973698 HIBCH HIBCH ACAT1 ACAT1 ENSPPAP00000024015 ENSPPAP00000024015 HMGCL HMGCL AGXT2 AGXT2 ECHS1 ECHS1 ALDH5A1 ALDH5A1 ACSL1 ACSL1 ACADL ACADL ACADM ACADM ACOX1 ACOX1 GLYR1 GLYR1 MCCC1 MCCC1 ECHDC1 ECHDC1 CPT2 CPT2 CPT1C CPT1C HTD2 HTD2 PCCA PCCA ETFB ETFB ACADSB ACADSB ALDH7A1 ALDH7A1 ACSM3 ACSM3 CBR4 CBR4 ACSM6 ACSM6 PCCB PCCB ENSPPAP00000030731 ENSPPAP00000030731 ENSPPAP00000030760 ENSPPAP00000030760 ACAD11 ACAD11 ECI1 ECI1 DIP2A DIP2A ACOXL ACOXL CAT CAT ACAA2 ACAA2 ETFA ETFA BDH2 BDH2 LOC100992292 LOC100992292 MCAT MCAT ACADVL ACADVL ECI2 ECI2 ACAA1-2 ACAA1-2 PECR PECR HADHB HADHB MLYCD MLYCD GLOD4 GLOD4 ACSS3 ACSS3 ACOT12 ACOT12 EHHADH EHHADH ALDH9A1 ALDH9A1 SLC27A4 SLC27A4 ACACA ACACA HSD17B4 HSD17B4 SLC27A1 SLC27A1 OLAH OLAH HIBADH HIBADH SCP2 SCP2 CHDH CHDH FASN FASN CRYL1 CRYL1 AMACR AMACR ACAA1 ACAA1 ACSS2 ACSS2 L1TD1 L1TD1 ACAT2 ACAT2 MCCC2 MCCC2 HADHA HADHA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ABAT4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (515 aa)
OXCT1Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. (557 aa)
ALDH1B1Aldehyde dehydrogenase 1 family member B1; Belongs to the aldehyde dehydrogenase family. (517 aa)
ACSL5Acyl-CoA synthetase long chain family member 5. (739 aa)
HSDL2Hydroxysteroid dehydrogenase like 2. (419 aa)
LOC100994494Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. (517 aa)
ACAD8Acyl-CoA dehydrogenase family member 8. (415 aa)
ACOX3Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (700 aa)
CRATCarnitine O-acetyltransferase; Belongs to the carnitine/choline acetyltransferase family. (626 aa)
AACSAcetoacetyl-CoA synthetase. (672 aa)
ACADSAcyl-CoA dehydrogenase short chain. (412 aa)
CPT1BCarnitine palmitoyltransferase 1B; Belongs to the carnitine/choline acetyltransferase family. (772 aa)
HPDL4-hydroxyphenylpyruvate dioxygenase. (371 aa)
CPT1ACarnitine palmitoyltransferase 1A; Belongs to the carnitine/choline acetyltransferase family. (773 aa)
ACYP1Acylphosphatase. (129 aa)
ACSS1Acetyl-coenzyme A synthetase. (670 aa)
ECH1Enoyl-CoA hydratase 1; Belongs to the enoyl-CoA hydratase/isomerase family. (328 aa)
DIP2BDisco interacting protein 2 homolog B. (1578 aa)
ACSL3Acyl-CoA synthetase long chain family member 3. (720 aa)
IVDIsovaleryl-CoA dehydrogenase. (426 aa)
ACYP2Acylphosphatase. (172 aa)
ACOX2Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (681 aa)
ALDH6A1Aldehyde dehydrogenase 6 family member A1. (535 aa)
AASDHPPTAminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase. (309 aa)
ENSPPAP000000158493-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite; Belongs to the enoyl-CoA hydratase/isomerase family. (311 aa)
ACSM4Acyl-CoA synthetase medium chain family member 4. (597 aa)
HMGCLL13-hydroxymethyl-3-methylglutaryl-CoA lyase like 1. (340 aa)
AASDHAminoadipate-semialdehyde dehydrogenase. (1080 aa)
ENSPPAP00000017735Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (457 aa)
ACSL4Acyl-CoA synthetase long chain family member 4. (749 aa)
HSD17B8Hydroxysteroid 17-beta dehydrogenase 8. (261 aa)
ENSPPAP00000018575Uncharacterized protein. (149 aa)
ACBD7Acyl-CoA binding domain containing 7. (88 aa)
OXSM3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial; May play a role in the biosynthesis of lipoic acid as well as longer chain fatty acids required for optimal mitochondrial function. Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (459 aa)
SCP2D1SCP2 sterol binding domain containing 1. (156 aa)
ACSBG1Acyl-CoA synthetase bubblegum family member 1. (724 aa)
HMGCS23-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (508 aa)
BDH13-hydroxybutyrate dehydrogenase 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (343 aa)
ECHDC2Enoyl-CoA hydratase domain containing 2; Belongs to the enoyl-CoA hydratase/isomerase family. (292 aa)
ETFDHElectron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone. (619 aa)
ACACBAcetyl-CoA carboxylase beta. (2458 aa)
SIRT3NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (342 aa)
HADHUncharacterized protein. (452 aa)
LOC100973698Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family. (712 aa)
HIBCH3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite; Belongs to the enoyl-CoA hydratase/isomerase family. (297 aa)
ACAT1Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. (427 aa)
ENSPPAP00000024015Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (354 aa)
HMGCL3-hydroxy-3-methylglutaryl-CoA lyase. (325 aa)
AGXT2Alanine--glyoxylate aminotransferase 2; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (514 aa)
ECHS1Enoyl-CoA hydratase, short chain 1; Belongs to the enoyl-CoA hydratase/isomerase family. (290 aa)
ALDH5A1Succinate-semialdehyde dehydrogenase, mitochondrial; Catalyzes one step in the degradation of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA); Belongs to the aldehyde dehydrogenase family. (548 aa)
ACSL1Acyl-CoA synthetase long chain family member 1. (698 aa)
ACADLAcyl-CoA dehydrogenase long chain. (430 aa)
ACADMAcyl-CoA dehydrogenase medium chain. (453 aa)
ACOX1Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (660 aa)
GLYR1Glyoxylate reductase 1 homolog. (553 aa)
MCCC1Methylcrotonoyl-CoA carboxylase 1. (725 aa)
ECHDC1Ethylmalonyl-CoA decarboxylase 1; Belongs to the enoyl-CoA hydratase/isomerase family. (303 aa)
CPT2Carnitine palmitoyltransferase 2; Belongs to the carnitine/choline acetyltransferase family. (658 aa)
CPT1CCarnitine palmitoyltransferase 1C; Belongs to the carnitine/choline acetyltransferase family. (745 aa)
HTD2Hydroxyacyl-thioester dehydratase type 2. (164 aa)
PCCAPropionyl-CoA carboxylase subunit alpha. (728 aa)
ETFBElectron transfer flavoprotein subunit beta. (293 aa)
ACADSBAcyl-CoA dehydrogenase short/branched chain. (432 aa)
ALDH7A1Aldedh domain-containing protein. (556 aa)
ACSM3Acyl-CoA synthetase medium chain family member 3. (586 aa)
CBR4Carbonyl reductase 4. (237 aa)
ACSM6Acyl-CoA synthetase medium chain family member 6. (480 aa)
PCCBPropionyl-CoA carboxylase subunit beta. (570 aa)
ENSPPAP00000030731Uncharacterized protein. (220 aa)
ENSPPAP00000030760Uncharacterized protein. (667 aa)
ACAD11Acyl-CoA dehydrogenase family member 11. (780 aa)
ECI1Enoyl-CoA delta isomerase 1; Belongs to the enoyl-CoA hydratase/isomerase family. (290 aa)
DIP2ADisco interacting protein 2 homolog A. (1563 aa)
ACOXLAcyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (580 aa)
CATCatalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (527 aa)
ACAA2Acetyl-CoA acyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. (397 aa)
ETFAElectron transfer flavoprotein subunit alpha. (333 aa)
BDH23-hydroxybutyrate dehydrogenase 2. (245 aa)
LOC100992292Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. (500 aa)
MCATMalonyl-CoA-acyl carrier protein transacylase. (390 aa)
ACADVLAcyl-CoA dehydrogenase very long chain. (677 aa)
ECI2Enoyl-CoA delta isomerase 2. (434 aa)
ACAA1-2Uncharacterized protein. (111 aa)
PECRPeroxisomal trans-2-enoyl-CoA reductase. (321 aa)
HADHBHydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta; Belongs to the thiolase-like superfamily. Thiolase family. (475 aa)
MLYCDMalonyl-CoA decarboxylase. (491 aa)
GLOD4Uncharacterized protein. (483 aa)
ACSS3Acyl-CoA synthetase short chain family member 3. (686 aa)
ACOT12Acyl-CoA thioesterase 12. (547 aa)
EHHADHEnoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase; Belongs to the enoyl-CoA hydratase/isomerase family. (723 aa)
ALDH9A1Aldehyde dehydrogenase 9 family member A1; Belongs to the aldehyde dehydrogenase family. (517 aa)
SLC27A4Solute carrier family 27 member 4. (647 aa)
ACACAAcetyl-CoA carboxylase alpha. (2383 aa)
HSD17B4Hydroxysteroid 17-beta dehydrogenase 4. (761 aa)
SLC27A1Solute carrier family 27 member 1. (646 aa)
OLAHOleoyl-ACP hydrolase. (280 aa)
HIBADH3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. (336 aa)
SCP2Sterol carrier protein 2; Belongs to the thiolase-like superfamily. Thiolase family. (547 aa)
CHDHCholine dehydrogenase. (577 aa)
FASNFatty acid synthase. (2511 aa)
CRYL1Crystallin lambda 1. (319 aa)
AMACRAlpha-methylacyl-CoA racemase. (382 aa)
ACAA1Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (299 aa)
ACSS2Acyl-CoA synthetase short chain family member 2. (714 aa)
L1TD1LINE1 type transposase domain containing 1. (864 aa)
ACAT2Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. (397 aa)
MCCC2Methylcrotonoyl-CoA carboxylase 2. (563 aa)
HADHAHydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha; Belongs to the enoyl-CoA hydratase/isomerase family. (763 aa)
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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