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ND2 ND2 COX1 COX1 COX2 COX2 ATP6 ATP6 COX3 COX3 ND3 ND3 ND4L ND4L ND4 ND4 ND5 ND5 ND6 ND6 CYTB CYTB COX7A2 COX7A2 NDUFS7 NDUFS7 NDUFAB1 NDUFAB1 CYC1 CYC1 ENSPPAP00000003283 ENSPPAP00000003283 UQCRHL UQCRHL NDUFA12 NDUFA12 OR10W1 OR10W1 NDUFV3 NDUFV3 ENSPPAP00000003907 ENSPPAP00000003907 ENSPPAP00000004015 ENSPPAP00000004015 COX7B2 COX7B2 ENSPPAP00000004862 ENSPPAP00000004862 TRIR TRIR ENSPPAP00000005990 ENSPPAP00000005990 NDUFA11 NDUFA11 LOC100967281 LOC100967281 PWWP3A PWWP3A YJEFN3 YJEFN3 NDUFB8 NDUFB8 COX6B2 COX6B2 ENSPPAP00000007590 ENSPPAP00000007590 NDUFB4 NDUFB4 NDUFA1 NDUFA1 UQCRQ UQCRQ LOC100983016 LOC100983016 LOC100985683 LOC100985683 COX8A COX8A COX5A-2 COX5A-2 NDUFA8 NDUFA8 UQCR10 UQCR10 NDUFA2 NDUFA2 ENSPPAP00000013152 ENSPPAP00000013152 UQCRFS1 UQCRFS1 NDUFS2 NDUFS2 NDUFS5 NDUFS5 COX6A2 COX6A2 ENSPPAP00000014905 ENSPPAP00000014905 NDUFS3 NDUFS3 NDUFS4 NDUFS4 NDUFS1 NDUFS1 NDUFB5 NDUFB5 NDUFV2 NDUFV2 ENSPPAP00000019251 ENSPPAP00000019251 ENSPPAP00000020079 ENSPPAP00000020079 ENSPPAP00000020139 ENSPPAP00000020139 COX7A2L COX7A2L COX7C COX7C UQCRC2 UQCRC2 NDUFB11 NDUFB11 UQCRC1 UQCRC1 C1orf198 C1orf198 NDUFA3 NDUFA3 ENSPPAP00000025587 ENSPPAP00000025587 NDUFA6 NDUFA6 UQCRH UQCRH ENSPPAP00000029278 ENSPPAP00000029278 NDUFA10 NDUFA10 NDUFB6 NDUFB6 COX7B COX7B ENSPPAP00000030325 ENSPPAP00000030325 NDUFA9 NDUFA9 NDUFS6 NDUFS6 COA6 COA6 NDUFC2 NDUFC2 NDUFS8 NDUFS8 NDUFB9 NDUFB9 COX6B1 COX6B1 NDUFB10 NDUFB10 COX4I1 COX4I1 COX4I2 COX4I2 NDUFB3 NDUFB3 ENSPPAP00000037199 ENSPPAP00000037199 COX5B COX5B COX6C COX6C COX5A COX5A COX6A1 COX6A1 NDUFV1 NDUFV1 NDUFB1 NDUFB1 NDUFA5 NDUFA5 NDUFA7 NDUFA7 NDUFB7 NDUFB7
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ND2NADH-ubiquinone oxidoreductase chain 2; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (347 aa)
COX1Cytochrome c oxidase subunit 1; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...] (513 aa)
COX2Cytochrome c oxidase subunit 2; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...] (227 aa)
ATP6ATP synthase subunit a; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subuni [...] (226 aa)
COX3Cytochrome c oxidase subunit 3; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...] (261 aa)
ND3NADH-ubiquinone oxidoreductase chain 3; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (115 aa)
ND4LNADH-ubiquinone oxidoreductase chain 4L; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (98 aa)
ND4NADH-ubiquinone oxidoreductase chain 4; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (459 aa)
ND5NADH-ubiquinone oxidoreductase chain 5; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (603 aa)
ND6NADH-ubiquinone oxidoreductase chain 6; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (174 aa)
CYTBCytochrome b; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis. (380 aa)
COX7A2Cytochrome c oxidase subunit 7A2. (115 aa)
NDUFS7NADH:ubiquinone oxidoreductase core subunit S7; Belongs to the complex I 20 kDa subunit family. (213 aa)
NDUFAB1Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (156 aa)
CYC1Cytochrome c1. (325 aa)
ENSPPAP00000003283Cytochrome c oxidase subunit 6A, mitochondrial. (109 aa)
UQCRHLCytochrome b-c1 complex subunit 6; This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This protein may mediate formation of the complex between cytochromes c and c1. Belongs to the UQCRH/QCR6 family. (93 aa)
NDUFA12NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (145 aa)
OR10W1Olfactory receptor. (305 aa)
NDUFV3NADH:ubiquinone oxidoreductase subunit V3. (473 aa)
ENSPPAP00000003907Uncharacterized protein. (150 aa)
ENSPPAP00000004015Uncharacterized protein. (58 aa)
COX7B2Cytochrome c oxidase subunit 7B2. (81 aa)
ENSPPAP00000004862Uncharacterized protein. (353 aa)
TRIRTelomerase RNA component interacting RNase. (172 aa)
ENSPPAP00000005990Uncharacterized protein. (95 aa)
NDUFA11NADH:ubiquinone oxidoreductase subunit A11. (228 aa)
LOC100967281Uncharacterized protein. (84 aa)
PWWP3APWWP domain containing 3A, DNA repair factor. (732 aa)
YJEFN3YjeF N-terminal domain containing 3. (299 aa)
NDUFB8NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (186 aa)
COX6B2Cytochrome c oxidase subunit 6B2. (88 aa)
ENSPPAP00000007590Uncharacterized protein. (234 aa)
NDUFB4NADH:ubiquinone oxidoreductase subunit B4. (129 aa)
NDUFA1NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (70 aa)
UQCRQUbiquinol-cytochrome c reductase complex III subunit VII. (82 aa)
LOC100983016Cytochrome b-c1 complex subunit 7; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain; Belongs to the UQCRB/QCR7 family. (101 aa)
LOC100985683Cytochrome b-c1 complex subunit 7; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain; Belongs to the UQCRB/QCR7 family. (111 aa)
COX8ACytochrome c oxidase subunit 8A, mitochondrial; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane [...] (69 aa)
COX5A-2Cytochrome c oxidase subunit 5A, mitochondrial; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane [...] (138 aa)
NDUFA8NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (172 aa)
UQCR10Ubiquinol-cytochrome c reductase, complex III subunit X. (63 aa)
NDUFA2L51_S25_CI-B8 domain-containing protein. (76 aa)
ENSPPAP00000013152Uncharacterized protein. (128 aa)
UQCRFS1Cytochrome b-c1 complex subunit Rieske, mitochondrial; [Cytochrome b-c1 complex subunit Rieske, mitochondrial]: Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b- c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and su [...] (274 aa)
NDUFS2NADH:ubiquinone oxidoreductase core subunit S2; Belongs to the complex I 49 kDa subunit family. (463 aa)
NDUFS5NADH:ubiquinone oxidoreductase subunit S5. (106 aa)
COX6A2Cytochrome c oxidase subunit 6A2. (87 aa)
ENSPPAP00000014905Cytochrome b-c1 complex subunit 7; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain; Belongs to the UQCRB/QCR7 family. (110 aa)
NDUFS3NADH:ubiquinone oxidoreductase core subunit S3; Belongs to the complex I 30 kDa subunit family. (264 aa)
NDUFS4NADH:ubiquinone oxidoreductase subunit S4. (175 aa)
NDUFS1NADH:ubiquinone oxidoreductase core subunit S1; Belongs to the complex I 75 kDa subunit family. (741 aa)
NDUFB5NADH:ubiquinone oxidoreductase subunit B5. (189 aa)
NDUFV2Uncharacterized protein. (252 aa)
ENSPPAP00000019251Uncharacterized protein. (62 aa)
ENSPPAP00000020079Uncharacterized protein. (80 aa)
ENSPPAP00000020139Uncharacterized protein. (113 aa)
COX7A2LCytochrome c oxidase subunit 7A2 like. (114 aa)
COX7CCytochrome c oxidase subunit 7C, mitochondrial; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane [...] (63 aa)
UQCRC2Ubiquinol-cytochrome c reductase core protein 2; Belongs to the peptidase M16 family. (453 aa)
NDUFB11NADH:ubiquinone oxidoreductase subunit B11. (163 aa)
UQCRC1Ubiquinol-cytochrome c reductase core protein 1. (480 aa)
C1orf198Chromosome 1 open reading frame 198. (327 aa)
NDUFA3Uncharacterized protein. (84 aa)
ENSPPAP00000025587Uncharacterized protein. (111 aa)
NDUFA6NADH:ubiquinone oxidoreductase subunit A6; Belongs to the complex I LYR family. (154 aa)
UQCRHCytochrome b-c1 complex subunit 6; This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This protein may mediate formation of the complex between cytochromes c and c1. Belongs to the UQCRH/QCR6 family. (91 aa)
ENSPPAP00000029278Uncharacterized protein. (123 aa)
NDUFA10NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (404 aa)
NDUFB6NADH:ubiquinone oxidoreductase subunit B6. (113 aa)
COX7BCytochrome c oxidase subunit 7B. (80 aa)
ENSPPAP00000030325Cytochrome b-c1 complex subunit 6; This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This protein may mediate formation of the complex between cytochromes c and c1. Belongs to the UQCRH/QCR6 family. (90 aa)
NDUFA9NADH:ubiquinone oxidoreductase subunit A9. (377 aa)
NDUFS6zf-CHCC domain-containing protein. (171 aa)
COA6Cytochrome c oxidase assembly factor 6. (155 aa)
NDUFC2NADH dehydrogenase [ubiquinone] 1 subunit C2; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (118 aa)
NDUFS8NADH:ubiquinone oxidoreductase core subunit S8. (210 aa)
NDUFB9NADH:ubiquinone oxidoreductase subunit B9; Belongs to the complex I LYR family. (179 aa)
COX6B1Cytochrome c oxidase subunit; Belongs to the cytochrome c oxidase subunit 6B. (86 aa)
NDUFB10NADH:ubiquinone oxidoreductase subunit B10. (172 aa)
COX4I1Cytochrome c oxidase subunit 4I1. (169 aa)
COX4I2Cytochrome c oxidase subunit 4I2. (171 aa)
NDUFB3NADH:ubiquinone oxidoreductase subunit B3. (98 aa)
ENSPPAP00000037199Uncharacterized protein. (247 aa)
COX5BCytochrome c oxidase subunit 5B. (129 aa)
COX6CCytochrome c oxidase subunit 6C. (75 aa)
COX5AUncharacterized protein. (139 aa)
COX6A1Cytochrome c oxidase subunit 6A, mitochondrial. (109 aa)
NDUFV1NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. (464 aa)
NDUFB1NADH:ubiquinone oxidoreductase subunit B1. (105 aa)
NDUFA5NADH:ubiquinone oxidoreductase subunit A5. (116 aa)
NDUFA7Uncharacterized protein. (113 aa)
NDUFB7NADH:ubiquinone oxidoreductase subunit B7. (137 aa)
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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