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EGF | Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1207 aa) | ||||
FGF9 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa) | ||||
GFRA2 | GDNF family receptor alpha-2; Receptor for neurturin. Mediates the NRTN-induced autophosphorylation and activation of the RET receptor. Also able to mediate GDNF signaling through the RET tyrosine kinase receptor. (460 aa) | ||||
ZAP70 | Tyrosine-protein kinase. (619 aa) | ||||
MATK | Tyrosine-protein kinase. (514 aa) | ||||
PIK3R3 | Phosphoinositide-3-kinase regulatory subunit 3. (478 aa) | ||||
CD84 | CD84 molecule. (345 aa) | ||||
PDGFA | PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (227 aa) | ||||
PAG1 | Phosphoprotein membrane anchor with glycosphingolipid microdomains 1. (432 aa) | ||||
CD3D | CD3d molecule. (171 aa) | ||||
GDNF | Glial cell derived neurotrophic factor. (228 aa) | ||||
STAP2 | Signal transducing adaptor family member 2. (407 aa) | ||||
KLB | Klotho beta. (1044 aa) | ||||
FLT3 | Fms related tyrosine kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (978 aa) | ||||
PECAM1 | Platelet and endothelial cell adhesion molecule 1. (738 aa) | ||||
IRS1 | Insulin receptor substrate 1. (1242 aa) | ||||
FLT3LG | Uncharacterized protein. (188 aa) | ||||
NTF4 | Neurotrophin 4; Belongs to the NGF-beta family. (210 aa) | ||||
FGFBP1 | Fibroblast growth factor binding protein 1. (234 aa) | ||||
FGF19 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (204 aa) | ||||
VAV3 | Vav guanine nucleotide exchange factor 3. (917 aa) | ||||
CD3G | CD3g molecule. (182 aa) | ||||
ENSPPAP00000006969 | Uncharacterized protein. (584 aa) | ||||
FCER1G | Uncharacterized protein. (112 aa) | ||||
CD72 | CD72 molecule. (359 aa) | ||||
VEGFA | Vascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (372 aa) | ||||
GRAP2 | GRB2 related adaptor protein 2. (330 aa) | ||||
PTPN1 | Tyrosine-protein phosphatase non-receptor type. (435 aa) | ||||
PTPN6 | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (603 aa) | ||||
ENSPPAP00000009275 | Uncharacterized protein. (269 aa) | ||||
ANGPT4 | Angiopoietin 4. (503 aa) | ||||
FRS2 | Fibroblast growth factor receptor substrate 2. (521 aa) | ||||
PTK6 | Tyrosine-protein kinase. (451 aa) | ||||
PTPN18 | Protein tyrosine phosphatase non-receptor type 18. (435 aa) | ||||
GRB2 | Growth factor receptor bound protein 2. (217 aa) | ||||
PIK3R2 | Uncharacterized protein. (663 aa) | ||||
PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1062 aa) | ||||
INSR | Tyrosine-protein kinase receptor. (1362 aa) | ||||
CSK | Tyrosine-protein kinase. (450 aa) | ||||
SHC3 | SHC adaptor protein 3. (501 aa) | ||||
GRAPL | GRB2 related adaptor protein like. (100 aa) | ||||
BDNF | Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. (329 aa) | ||||
FGR | Tyrosine-protein kinase. (529 aa) | ||||
CLEC7A | C-type lectin domain containing 7A. (247 aa) | ||||
NRG1 | Neuregulin 1. (645 aa) | ||||
RALGPS1 | Ral GEF with PH domain and SH3 binding motif 1. (557 aa) | ||||
PDGFB | Platelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (241 aa) | ||||
ANGPTL1 | Angiopoietin like 1. (491 aa) | ||||
GAB2 | GRB2 associated binding protein 2. (675 aa) | ||||
KL | Klotho. (1032 aa) | ||||
TEC | Tyrosine-protein kinase. (631 aa) | ||||
ENSPPAP00000014225 | Protein kinase domain-containing protein. (433 aa) | ||||
LYN | Tyrosine-protein kinase. (526 aa) | ||||
SHC1 | SHC adaptor protein 1. (584 aa) | ||||
CD2 | CD2 molecule. (351 aa) | ||||
FCGR2A | Fc fragment of IgG receptor IIa. (316 aa) | ||||
INPP5D | Inositol polyphosphate-5-phosphatase D. (1189 aa) | ||||
ENSPPAP00000015671 | Protein kinase domain-containing protein. (414 aa) | ||||
PGF | PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (221 aa) | ||||
SLAMF1 | Signaling lymphocytic activation molecule family member 1. (356 aa) | ||||
LCK | Tyrosine-protein kinase. (524 aa) | ||||
FGF20 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (212 aa) | ||||
FGFR1 | Fibroblast growth factor receptor. (812 aa) | ||||
FGF5 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (268 aa) | ||||
KITLG | Kit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. (273 aa) | ||||
FGF22 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (166 aa) | ||||
ITK | Tyrosine-protein kinase. (620 aa) | ||||
GFRA1 | GDNF family receptor alpha-1; Receptor for GDNF. Mediates the GDNF-induced autophosphorylation and activation of the RET receptor. Belongs to the GDNFR family. (467 aa) | ||||
PIK3CB | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1084 aa) | ||||
ANGPT2 | Angiopoietin 2. (495 aa) | ||||
CD3E | CD3e molecule. (207 aa) | ||||
PLCG1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1248 aa) | ||||
PDGFRA | Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1089 aa) | ||||
SRMS | Tyrosine-protein kinase. (491 aa) | ||||
PDGFRL | Platelet derived growth factor receptor like. (448 aa) | ||||
KHDRBS2 | KH RNA binding domain containing, signal transduction associated 2. (349 aa) | ||||
CD101 | CD101 molecule. (1017 aa) | ||||
KIT | Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (976 aa) | ||||
BTC | Betacellulin. (178 aa) | ||||
FLT1 | Uncharacterized protein. (736 aa) | ||||
NRG4 | Neuregulin 4. (117 aa) | ||||
INSRR | Tyrosine-protein kinase receptor. (1297 aa) | ||||
FGF21 | Uncharacterized protein. (147 aa) | ||||
NRG3 | Neuregulin 3. (719 aa) | ||||
FGFRL1 | Fibroblast growth factor receptor like 1. (507 aa) | ||||
PDGFD | Platelet derived growth factor D. (329 aa) | ||||
PIK3R6 | Phosphoinositide-3-kinase regulatory subunit 6. (754 aa) | ||||
SLAMF7 | SLAM family member 7. (335 aa) | ||||
FGF16 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa) | ||||
FGF23 | Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (251 aa) | ||||
RET | Proto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. (1116 aa) | ||||
FGFR3 | Fibroblast growth factor receptor. (780 aa) | ||||
DOK4 | Docking protein 4. (365 aa) | ||||
TEK | TEK receptor tyrosine kinase. (1124 aa) | ||||
FGF11 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa) | ||||
PTPRC | Protein tyrosine phosphatase receptor type C. (1261 aa) | ||||
NTRK1 | Tyrosine-protein kinase receptor. (796 aa) | ||||
FGFR2 | Fibroblast growth factor receptor. (822 aa) | ||||
HGF | Hepatocyte growth factor; Belongs to the peptidase S1 family. (812 aa) | ||||
SORT1 | Sortilin. (569 aa) | ||||
ENSPPAP00000024034 | Uncharacterized protein. (541 aa) | ||||
NRG2 | Uncharacterized protein. (705 aa) | ||||
STYK1 | Serine/threonine/tyrosine kinase 1. (422 aa) | ||||
CD244 | CD244 molecule. (367 aa) | ||||
ERBB3 | Erb-b2 receptor tyrosine kinase 3. (1344 aa) | ||||
LCP2 | Lymphocyte cytosolic protein 2. (533 aa) | ||||
PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) | ||||
PTPN11 | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (594 aa) | ||||
ENSPPAP00000025160 | Tyrosine-protein kinase. (483 aa) | ||||
FGF13 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (245 aa) | ||||
FYN | Tyrosine-protein kinase. (537 aa) | ||||
PTPN22 | Protein tyrosine phosphatase non-receptor type 22. (807 aa) | ||||
PIK3R5 | Phosphoinositide-3-kinase regulatory subunit 5. (883 aa) | ||||
ANGPT1 | Angiopoietin 1. (498 aa) | ||||
SLAMF6 | SLAM family member 6. (331 aa) | ||||
SORCS2 | Sortilin related VPS10 domain containing receptor 2. (1027 aa) | ||||
ZNRF1 | Zinc and ring finger 1. (278 aa) | ||||
VAV1 | Vav guanine nucleotide exchange factor 1. (828 aa) | ||||
TIE1 | Tyrosine kinase with immunoglobulin like and EGF like domains 1. (1138 aa) | ||||
CD58 | CD58 molecule. (250 aa) | ||||
FGFR4 | Fibroblast growth factor receptor. (802 aa) | ||||
FGF7 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa) | ||||
CD52 | CD52 molecule. (61 aa) | ||||
CD22 | B-cell receptor CD22; Mediates B-cell B-cell interactions. May be involved in the localization of B-cells in lymphoid tissues. Binds sialylated glycoproteins; one of which is CD45. Preferentially binds to alpha-2,6- linked sialic acid (By similarity). Upon ligand-induced tyrosine phosphorylation in the immune response seems to be involved in regulation of B-cell antigen receptor signaling. Plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that b [...] (847 aa) | ||||
TXK | Tyrosine-protein kinase. (527 aa) | ||||
PDGFRB | Platelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1106 aa) | ||||
LAT | Linker for activation of T cells. (268 aa) | ||||
VAV2 | Vav guanine nucleotide exchange factor 2. (810 aa) | ||||
ENSPPAP00000029143 | Uncharacterized protein. (511 aa) | ||||
SYK | Tyrosine-protein kinase. (635 aa) | ||||
NTRK2 | Tyrosine-protein kinase receptor. (838 aa) | ||||
HCK | Tyrosine-protein kinase. (526 aa) | ||||
MET | MET proto-oncogene, receptor tyrosine kinase. (1413 aa) | ||||
LOC100984838 | Uncharacterized protein. (334 aa) | ||||
CD53 | Tetraspanin. (219 aa) | ||||
PSPN | Persephin. (156 aa) | ||||
FGF14 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (296 aa) | ||||
CLEC11A | C-type lectin domain containing 11A. (323 aa) | ||||
BTK | Tyrosine-protein kinase. (693 aa) | ||||
VEGFB | Vascular endothelial growth factor B; Belongs to the PDGF/VEGF growth factor family. (186 aa) | ||||
CD48 | CD48 molecule. (252 aa) | ||||
YES1 | Tyrosine-protein kinase. (548 aa) | ||||
PDGFC | Platelet derived growth factor C; Belongs to the PDGF/VEGF growth factor family. (345 aa) | ||||
DOK2 | Docking protein 2. (412 aa) | ||||
FGF10 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa) | ||||
GAB1 | GRB2 associated binding protein 1. (724 aa) | ||||
SH2D1A | SH2 domain-containing protein 1A; Cytoplasmic adapter regulating receptors of the signaling lymphocytic activation molecule (SLAM) family such as SLAMF1, CD244, LY9, CD84, SLAMF6 and SLAMF7. In SLAM signaling seems to cooperate with SH2D1B/EAT-2. (128 aa) | ||||
FER | Tyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (798 aa) | ||||
PLCG2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa) | ||||
NGFR | Nerve growth factor receptor. (427 aa) | ||||
FCGR1A | Uncharacterized protein. (368 aa) | ||||
IRS4 | Insulin receptor substrate 4. (1194 aa) | ||||
NGF | NGF domain-containing protein; Belongs to the NGF-beta family. (123 aa) | ||||
FGF8 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (210 aa) | ||||
GRAP | Uncharacterized protein. (158 aa) | ||||
BLNK | B cell linker. (417 aa) | ||||
GP6 | Glycoprotein VI platelet. (606 aa) | ||||
FGF6 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa) | ||||
LOC103785316 | Ig-like domain-containing protein. (221 aa) | ||||
SOS2 | SOS Ras/Rho guanine nucleotide exchange factor 2. (1325 aa) | ||||
SRC | Tyrosine-protein kinase. (458 aa) | ||||
FGF1 | Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa) | ||||
LY9 | Lymphocyte antigen 9. (655 aa) | ||||
CBLC | Uncharacterized protein. (387 aa) | ||||
ERBB2 | Receptor protein-tyrosine kinase. (1255 aa) | ||||
ERBB4 | Receptor protein-tyrosine kinase. (1386 aa) | ||||
CD8B | Ig-like domain-containing protein. (243 aa) | ||||
VEGFD | Vascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family. (354 aa) | ||||
CSF1R | Colony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (972 aa) | ||||
FGF2 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (260 aa) | ||||
FGF3 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (218 aa) | ||||
FRS3 | Fibroblast growth factor receptor substrate 3. (492 aa) | ||||
PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (736 aa) | ||||
FLT4 | Fms related tyrosine kinase 4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1321 aa) | ||||
PIK3AP1 | Phosphoinositide-3-kinase adaptor protein 1. (805 aa) | ||||
AREG | EGF-like domain-containing protein. (274 aa) | ||||
GFRA3 | GDNF family receptor alpha 3. (400 aa) | ||||
EREG | Epiregulin. (169 aa) | ||||
CSF1 | Macrophage colony-stimulating factor 1; Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female [...] (549 aa) | ||||
KDR | Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa) | ||||
CD8A | CD8a molecule. (226 aa) | ||||
FGF17 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (205 aa) | ||||
CD247 | CD247 molecule. (163 aa) | ||||
PIK3CG | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma; Belongs to the PI3/PI4-kinase family. (1102 aa) | ||||
TGFA | Transforming growth factor alpha. (181 aa) | ||||
SHC2 | Uncharacterized protein. (539 aa) | ||||
VEGFC | Vascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (418 aa) | ||||
NTF3 | Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. (275 aa) | ||||
IL34 | Interleukin 34. (242 aa) | ||||
EPGN | Uncharacterized protein. (85 aa) | ||||
FGF18 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (196 aa) | ||||
KHDRBS3 | KH RNA binding domain containing, signal transduction associated 3. (346 aa) | ||||
INPPL1 | Inositol polyphosphate phosphatase like 1. (1253 aa) | ||||
EGFR | Receptor protein-tyrosine kinase. (1201 aa) |