(5 nodes) GRB2-associated-binding protein 1-4-like, and Core histone H2A/H2B/H3/H4 network (Pan paniscus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	GRB2	Growth factor receptor bound protein 2. (217 aa)
	GAB2	GRB2 associated binding protein 2. (675 aa)
	PTPN11	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (594 aa)
	GAB1	GRB2 associated binding protein 1. (724 aa)
	SOS2	SOS Ras/Rho guanine nucleotide exchange factor 2. (1325 aa)

Your Current Organism:

Pan paniscus

NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GAB1	GAB2	ENSPPAP00000033073	ENSPPAP00000013640	GRB2 associated binding protein 1.	GRB2 associated binding protein 2.	0.930
GAB1	GRB2	ENSPPAP00000033073	ENSPPAP00000009849	GRB2 associated binding protein 1.	Growth factor receptor bound protein 2.	0.999
GAB1	PTPN11	ENSPPAP00000033073	ENSPPAP00000025051	GRB2 associated binding protein 1.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.997
GAB1	SOS2	ENSPPAP00000033073	ENSPPAP00000035804	GRB2 associated binding protein 1.	SOS Ras/Rho guanine nucleotide exchange factor 2.	0.974
GAB2	GAB1	ENSPPAP00000013640	ENSPPAP00000033073	GRB2 associated binding protein 2.	GRB2 associated binding protein 1.	0.930
GAB2	GRB2	ENSPPAP00000013640	ENSPPAP00000009849	GRB2 associated binding protein 2.	Growth factor receptor bound protein 2.	0.969
GAB2	PTPN11	ENSPPAP00000013640	ENSPPAP00000025051	GRB2 associated binding protein 2.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.937
GAB2	SOS2	ENSPPAP00000013640	ENSPPAP00000035804	GRB2 associated binding protein 2.	SOS Ras/Rho guanine nucleotide exchange factor 2.	0.922
GRB2	GAB1	ENSPPAP00000009849	ENSPPAP00000033073	Growth factor receptor bound protein 2.	GRB2 associated binding protein 1.	0.999
GRB2	GAB2	ENSPPAP00000009849	ENSPPAP00000013640	Growth factor receptor bound protein 2.	GRB2 associated binding protein 2.	0.969
GRB2	PTPN11	ENSPPAP00000009849	ENSPPAP00000025051	Growth factor receptor bound protein 2.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.999
GRB2	SOS2	ENSPPAP00000009849	ENSPPAP00000035804	Growth factor receptor bound protein 2.	SOS Ras/Rho guanine nucleotide exchange factor 2.	0.999
PTPN11	GAB1	ENSPPAP00000025051	ENSPPAP00000033073	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	GRB2 associated binding protein 1.	0.997
PTPN11	GAB2	ENSPPAP00000025051	ENSPPAP00000013640	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	GRB2 associated binding protein 2.	0.937
PTPN11	GRB2	ENSPPAP00000025051	ENSPPAP00000009849	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	Growth factor receptor bound protein 2.	0.999
PTPN11	SOS2	ENSPPAP00000025051	ENSPPAP00000035804	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	SOS Ras/Rho guanine nucleotide exchange factor 2.	0.981
SOS2	GAB1	ENSPPAP00000035804	ENSPPAP00000033073	SOS Ras/Rho guanine nucleotide exchange factor 2.	GRB2 associated binding protein 1.	0.974
SOS2	GAB2	ENSPPAP00000035804	ENSPPAP00000013640	SOS Ras/Rho guanine nucleotide exchange factor 2.	GRB2 associated binding protein 2.	0.922
SOS2	GRB2	ENSPPAP00000035804	ENSPPAP00000009849	SOS Ras/Rho guanine nucleotide exchange factor 2.	Growth factor receptor bound protein 2.	0.999
SOS2	PTPN11	ENSPPAP00000035804	ENSPPAP00000025051	SOS Ras/Rho guanine nucleotide exchange factor 2.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.981