STRINGSTRING
NIP7 NIP7 GNL2 GNL2 UTP20 UTP20 LOC100994493 LOC100994493 MCC MCC WDR75 WDR75 ENSPPAP00000001395 ENSPPAP00000001395 DDX55 DDX55 MDN1 MDN1 IMP3 IMP3 NOL10 NOL10 KRR1 KRR1 RSL24D1 RSL24D1 DHX37 DHX37 ENSPPAP00000003988 ENSPPAP00000003988 GNL3 GNL3 UTP3 UTP3 LOC100988174 LOC100988174 LOC100986453 LOC100986453 WDR36 WDR36 RRS1 RRS1 ESF1 ESF1 PDCD11 PDCD11 P2RY1 P2RY1 SNU13 SNU13 FTSJ3 FTSJ3 NOP56 NOP56 DDX31 DDX31 PAK1IP1 PAK1IP1 BMS1 BMS1 REXO4 REXO4 RRP9 RRP9 UTP4 UTP4 ZNF622 ZNF622 DDX52 DDX52 NOL7 NOL7 UTP23 UTP23 ENSPPAP00000010956 ENSPPAP00000010956 ENSPPAP00000011215 ENSPPAP00000011215 IMP4 IMP4 ENSPPAP00000011414 ENSPPAP00000011414 LOC100976089 LOC100976089 RRP1 RRP1 WDR3 WDR3 DDX56 DDX56 PWP1 PWP1 LSG1 LSG1 ENSPPAP00000012297 ENSPPAP00000012297 ENSPPAP00000012368 ENSPPAP00000012368 DCAF13 DCAF13 WDR46 WDR46 ENSPPAP00000013012 ENSPPAP00000013012 PES1 PES1 ENSPPAP00000013286 ENSPPAP00000013286 ZNF593 ZNF593 UTP11 UTP11 NOP2 NOP2 ENSPPAP00000014695 ENSPPAP00000014695 RBM34 RBM34 PINX1 PINX1 EIF6 EIF6 ENSPPAP00000015877 ENSPPAP00000015877 ENSPPAP00000016332 ENSPPAP00000016332 ENSPPAP00000016348 ENSPPAP00000016348 NEXN NEXN NLE1 NLE1 UTP15 UTP15 MPHOSPH10 MPHOSPH10 ENSPPAP00000017938 ENSPPAP00000017938 SURF6 SURF6 NOL12 NOL12 ENSPPAP00000018732 ENSPPAP00000018732 NOL11 NOL11 NOP53 NOP53 EMG1 EMG1 ENSPPAP00000019735 ENSPPAP00000019735 LOC100988838 LOC100988838 DDX18 DDX18 ENSPPAP00000020590 ENSPPAP00000020590 WDR12 WDR12 UTP18 UTP18 FBL FBL GNL3L GNL3L PMEL PMEL NIFK NIFK MAK16 MAK16 RTCA RTCA DDX49 DDX49 DDX10 DDX10 RRP1B RRP1B RPF2 RPF2 ENSPPAP00000025066 ENSPPAP00000025066 NOC2L NOC2L DDX27 DDX27 WDR74 WDR74 NAT10 NAT10 LYAR LYAR HEATR1 HEATR1 NOP58 NOP58 NOP14 NOP14 ENSPPAP00000029406 ENSPPAP00000029406 PWP2 PWP2 RCL1 RCL1 UTP6 UTP6 BRIX1 BRIX1 EBNA1BP2 EBNA1BP2 RPF1 RPF1 DDX24 DDX24 NOP9 NOP9 SDAD1 SDAD1 NGDN NGDN KCTD19 KCTD19 ENSPPAP00000033416 ENSPPAP00000033416 GLMN GLMN RSL1D1 RSL1D1 PPAN PPAN DDX47 DDX47 UTP14C UTP14C KRI1 KRI1 ENSPPAP00000034922 ENSPPAP00000034922 ENSPPAP00000035917 ENSPPAP00000035917 ENSPPAP00000036245 ENSPPAP00000036245 ENSPPAP00000036270 ENSPPAP00000036270 NOL6 NOL6 ENSPPAP00000036942 ENSPPAP00000036942 AATF AATF PUM3 PUM3 NOM1 NOM1 RBM28 RBM28 ENSPPAP00000038146 ENSPPAP00000038146 P2RY11 P2RY11 TBL3 TBL3 WDR43 WDR43 GTPBP4 GTPBP4 RRP15 RRP15 DDX54 DDX54 FCF1 FCF1 NSUN6 NSUN6 UTP14A UTP14A NOC4L NOC4L NSA2 NSA2 ENSPPAP00000040354 ENSPPAP00000040354 ENSPPAP00000040440 ENSPPAP00000040440 BOP1 BOP1 C1orf131 C1orf131 CEBPZ CEBPZ WDR17 WDR17 ENSPPAP00000041825 ENSPPAP00000041825 UTP25 UTP25 RBM19 RBM19 MRTO4 MRTO4 NOC3L NOC3L NMD3 NMD3 ENSPPAP00000042680 ENSPPAP00000042680 ABT1 ABT1 DNTTIP2 DNTTIP2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NIP760S ribosome subunit biogenesis protein NIP7 homolog; Required for proper 34S pre-rRNA processing and 60S ribosome subunit assembly; Belongs to the NIP7 family. (180 aa)
GNL2Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily. (794 aa)
UTP20UTP20 small subunit processome component. (2785 aa)
LOC100994493Ribosome biogenesis protein NOP53; May play a role in ribosome biogenesis. Belongs to the NOP53 family. (476 aa)
MCCMCC regulator of WNT signaling pathway. (910 aa)
WDR75WD repeat domain 75. (830 aa)
ENSPPAP0000000139560S ribosome subunit biogenesis protein NIP7 homolog; Required for proper 34S pre-rRNA processing and 60S ribosome subunit assembly; Belongs to the NIP7 family. (164 aa)
DDX55RNA helicase. (600 aa)
MDN1Midasin; Nuclear chaperone required for maturation and nuclear export of pre-60S ribosome subunits; Belongs to the midasin family. (5596 aa)
IMP3IMP U3 small nucleolar ribonucleoprotein 3. (184 aa)
NOL10Nucleolar protein 10. (688 aa)
KRR1KRR1 small subunit processome component; Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly. (381 aa)
RSL24D1Uncharacterized protein. (71 aa)
DHX37DEAH-box helicase 37. (1155 aa)
ENSPPAP00000003988Uncharacterized protein. (527 aa)
GNL3G protein nucleolar 3. (549 aa)
UTP3UTP3 small subunit processome component. (479 aa)
LOC100988174WD_REPEATS_REGION domain-containing protein. (446 aa)
LOC100986453RRP7 domain-containing protein. (276 aa)
WDR36WD repeat domain 36. (895 aa)
RRS1Ribosome biogenesis regulatory protein; Involved in ribosomal large subunit assembly. Belongs to the RRS1 family. (365 aa)
ESF1ESF1 nucleolar pre-rRNA processing protein homolog. (845 aa)
PDCD11Programmed cell death 11. (1833 aa)
P2RY1Purinergic receptor P2Y1; Belongs to the G-protein coupled receptor 1 family. (373 aa)
SNU13Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (132 aa)
FTSJ3pre-rRNA processing protein FTSJ3; Probable methyltransferase involved in the processing of the 34S pre-rRNA to 18S rRNA and in 40S ribosomal subunit formation. Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily. (846 aa)
NOP56NOP56 ribonucleoprotein. (594 aa)
DDX31RNA helicase. (851 aa)
PAK1IP1PAK1 interacting protein 1. (392 aa)
BMS1BMS1 ribosome biogenesis factor. (1260 aa)
REXO4REX4 homolog, 3'-5' exonuclease. (422 aa)
RRP9Ribosomal RNA processing 9, U3 small nucleolar RNA binding protein. (475 aa)
UTP4UTP4 small subunit processome component. (686 aa)
ZNF622Zinc finger protein 622. (477 aa)
DDX52DExD-box helicase 52. (589 aa)
NOL7Nucleolar protein 7. (257 aa)
UTP23UTP23 small subunit processome component. (249 aa)
ENSPPAP00000010956RRM domain-containing protein. (251 aa)
ENSPPAP00000011215Uncharacterized protein. (348 aa)
IMP4IMP U3 small nucleolar ribonucleoprotein 4. (291 aa)
ENSPPAP00000011414Uncharacterized protein. (249 aa)
LOC100976089Bms1-type G domain-containing protein. (186 aa)
RRP1Ribosomal RNA processing 1. (461 aa)
WDR3WD repeat domain 3. (943 aa)
DDX56DEAD-box helicase 56. (556 aa)
PWP1PWP1 homolog, endonuclein. (501 aa)
LSG1Large 60S subunit nuclear export GTPase 1. (658 aa)
ENSPPAP00000012297Ribosome biogenesis protein NOP53; May play a role in ribosome biogenesis. Belongs to the NOP53 family. (453 aa)
ENSPPAP00000012368Uncharacterized protein. (225 aa)
DCAF13DDB1 and CUL4 associated factor 13. (597 aa)
WDR46WD repeat domain 46. (610 aa)
ENSPPAP00000013012Protein SDA1; Required for 60S pre-ribosomal subunits export to the cytoplasm; Belongs to the SDA1 family. (197 aa)
PES1Pescadillo homolog; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome; Belongs to the pescadillo family. (587 aa)
ENSPPAP00000013286RRP7 domain-containing protein. (231 aa)
ZNF593Zinc finger protein 593. (134 aa)
UTP11U3 small nucleolar RNA-associated protein 11; Involved in nucleolar processing of pre-18S ribosomal RNA. (270 aa)
NOP2NOP2 nucleolar protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (845 aa)
ENSPPAP00000014695Uncharacterized protein; Belongs to the DEAD box helicase family. (605 aa)
RBM34RNA binding motif protein 34. (422 aa)
PINX1PIN2 (TERF1) interacting telomerase inhibitor 1. (332 aa)
EIF6Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Behaves as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (RACK1)- dependent protein kinase C activity. In tissues responsive to insulin, contro [...] (245 aa)
ENSPPAP00000015877Uncharacterized protein. (251 aa)
ENSPPAP00000016332Uncharacterized protein. (512 aa)
ENSPPAP00000016348TRASH domain-containing protein. (150 aa)
NEXNNexilin F-actin binding protein. (675 aa)
NLE1Notchless homolog 1. (485 aa)
UTP15UTP15 small subunit processome component. (503 aa)
MPHOSPH10U3 small nucleolar ribonucleoprotein protein MPP10; Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing; Belongs to the MPP10 family. (681 aa)
ENSPPAP00000017938Brix domain-containing protein. (280 aa)
SURF6Surfeit 6. (361 aa)
NOL12Uncharacterized protein. (213 aa)
ENSPPAP00000018732Uncharacterized protein; Belongs to the DEAD box helicase family. (805 aa)
NOL11Nucleolar protein 11. (719 aa)
NOP53Ribosome biogenesis protein NOP53; May play a role in ribosome biogenesis. Belongs to the NOP53 family. (427 aa)
EMG1EMG1 N1-specific pseudouridine methyltransferase. (244 aa)
ENSPPAP00000019735RRM domain-containing protein. (240 aa)
LOC100988838Protein SDA1; Required for 60S pre-ribosomal subunits export to the cytoplasm; Belongs to the SDA1 family. (601 aa)
DDX18RNA helicase. (670 aa)
ENSPPAP00000020590Uncharacterized protein. (74 aa)
WDR12Ribosome biogenesis protein WDR12; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (433 aa)
UTP18UTP18 small subunit processome component. (554 aa)
FBLFibrillarin. (336 aa)
GNL3LG protein nucleolar 3 like. (582 aa)
PMELPremelanosome protein. (705 aa)
NIFKNucleolar protein interacting with the FHA domain of MKI67. (293 aa)
MAK16Protein MAK16 homolog; Belongs to the MAK16 family. (300 aa)
RTCARNA 3'-terminal phosphate cyclase. (379 aa)
DDX49DEAD-box helicase 49; Belongs to the DEAD box helicase family. (483 aa)
DDX10RNA helicase. (876 aa)
RRP1BRibosomal RNA processing 1B. (747 aa)
RPF2Ribosome production factor 2 homolog. (306 aa)
ENSPPAP00000025066Uncharacterized protein. (183 aa)
NOC2LNOC2 like nucleolar associated transcriptional repressor. (712 aa)
DDX27DEAD-box helicase 27; Belongs to the DEAD box helicase family. (759 aa)
WDR74WD repeat domain 74. (385 aa)
NAT10RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein THUMPD1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation. (1034 aa)
LYARLy1 antibody reactive. (379 aa)
HEATR1HEAT repeat containing 1. (2144 aa)
NOP58NOP58 ribonucleoprotein. (539 aa)
NOP14NOP14 nucleolar protein. (857 aa)
ENSPPAP00000029406Uncharacterized protein. (165 aa)
PWP2Uncharacterized protein. (919 aa)
RCL1RNA terminal phosphate cyclase like 1. (373 aa)
UTP6UTP6 small subunit processome component. (597 aa)
BRIX1Biogenesis of ribosomes BRX1. (353 aa)
EBNA1BP2EBNA1 binding protein 2. (361 aa)
RPF1Ribosome production factor 1 homolog. (349 aa)
DDX24DEAD-box helicase 24. (859 aa)
NOP9NOP9 nucleolar protein. (634 aa)
SDAD1Protein SDA1; Required for 60S pre-ribosomal subunits export to the cytoplasm; Belongs to the SDA1 family. (687 aa)
NGDNNeuroguidin. (315 aa)
KCTD19Potassium channel tetramerization domain containing 19. (926 aa)
ENSPPAP00000033416Uncharacterized protein. (208 aa)
GLMNGlomulin, FKBP associated protein. (594 aa)
RSL1D1Ribosomal L1 domain containing 1. (490 aa)
PPANPeter pan homolog. (473 aa)
DDX47DEAD-box helicase 47; Belongs to the DEAD box helicase family. (455 aa)
UTP14CUTP14C small subunit processome component. (774 aa)
KRI1KRI1 homolog. (705 aa)
ENSPPAP00000034922G domain-containing protein. (487 aa)
ENSPPAP00000035917TRASH domain-containing protein. (182 aa)
ENSPPAP00000036245Uncharacterized protein. (132 aa)
ENSPPAP00000036270RRM domain-containing protein. (244 aa)
NOL6Nucleolar protein 6. (1155 aa)
ENSPPAP00000036942Uncharacterized protein. (138 aa)
AATFApoptosis antagonizing transcription factor. (560 aa)
PUM3Pumilio RNA binding family member 3. (648 aa)
NOM1Nucleolar protein with MIF4G domain 1. (859 aa)
RBM28RNA binding motif protein 28. (761 aa)
ENSPPAP00000038146Uncharacterized protein. (66 aa)
P2RY11Purinergic receptor P2Y11; Belongs to the G-protein coupled receptor 1 family. (374 aa)
TBL3Transducin beta like 3. (808 aa)
WDR43WD repeat domain 43. (601 aa)
GTPBP4Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily. (634 aa)
RRP15Ribosomal RNA processing 15 homolog. (285 aa)
DDX54ATP-dependent RNA helicase DDX54; Belongs to the DEAD box helicase family. DDX54/DBP10 subfamily. (885 aa)
FCF1FCF1 rRNA-processing protein. (200 aa)
NSUN6NOP2/Sun RNA methyltransferase 6; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (469 aa)
UTP14AUTP14A small subunit processome component. (771 aa)
NOC4LNucleolar complex associated 4 homolog. (517 aa)
NSA2NSA2 ribosome biogenesis factor. (260 aa)
ENSPPAP00000040354Uncharacterized protein. (241 aa)
ENSPPAP00000040440Uncharacterized protein. (252 aa)
BOP1Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (712 aa)
C1orf131Chromosome 1 open reading frame 131. (294 aa)
CEBPZCCAAT enhancer binding protein zeta. (1054 aa)
WDR17WD repeat domain 17. (1314 aa)
ENSPPAP00000041825Uncharacterized protein. (372 aa)
UTP25UTP25 small subunit processor component. (756 aa)
RBM19RNA binding motif protein 19. (961 aa)
MRTO4Ribosome assembly factor mrt4; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes. (239 aa)
NOC3LNucleolar complex protein 3 homolog. (800 aa)
NMD360S ribosomal export protein NMD3; Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit; Belongs to the NMD3 family. (529 aa)
ENSPPAP00000042680NUC205 domain-containing protein. (673 aa)
ABT1Activator of basal transcription 1. (272 aa)
DNTTIP2Deoxynucleotidyltransferase terminal interacting protein 2. (756 aa)
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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