STRINGSTRING
NIP7 NIP7 GNL2 GNL2 LOC100994493 LOC100994493 ENSPPAP00000001395 ENSPPAP00000001395 MDN1 MDN1 RSL24D1 RSL24D1 GNL3 GNL3 LOC100988174 LOC100988174 RRS1 RRS1 FTSJ3 FTSJ3 PAK1IP1 PAK1IP1 ZNF622 ZNF622 UTP23 UTP23 ENSPPAP00000010956 ENSPPAP00000010956 ENSPPAP00000011414 ENSPPAP00000011414 RRP1 RRP1 DDX56 DDX56 PWP1 PWP1 LSG1 LSG1 ENSPPAP00000012297 ENSPPAP00000012297 ENSPPAP00000012368 ENSPPAP00000012368 ENSPPAP00000013012 ENSPPAP00000013012 PES1 PES1 ZNF593 ZNF593 NOP2 NOP2 ENSPPAP00000014695 ENSPPAP00000014695 RBM34 RBM34 EIF6 EIF6 ENSPPAP00000015877 ENSPPAP00000015877 ENSPPAP00000016348 ENSPPAP00000016348 NLE1 NLE1 ENSPPAP00000017938 ENSPPAP00000017938 SURF6 SURF6 NOL12 NOL12 NOP53 NOP53 ENSPPAP00000019735 ENSPPAP00000019735 LOC100988838 LOC100988838 DDX18 DDX18 WDR12 WDR12 GNL3L GNL3L NIFK NIFK MAK16 MAK16 RRP1B RRP1B RPF2 RPF2 NOC2L NOC2L DDX27 DDX27 WDR74 WDR74 BRIX1 BRIX1 EBNA1BP2 EBNA1BP2 RPF1 RPF1 DDX24 DDX24 SDAD1 SDAD1 KCTD19 KCTD19 ENSPPAP00000033416 ENSPPAP00000033416 RSL1D1 RSL1D1 PPAN PPAN ENSPPAP00000034922 ENSPPAP00000034922 ENSPPAP00000035917 ENSPPAP00000035917 ENSPPAP00000036245 ENSPPAP00000036245 ENSPPAP00000036270 ENSPPAP00000036270 ENSPPAP00000036942 ENSPPAP00000036942 PUM3 PUM3 RBM28 RBM28 P2RY11 P2RY11 GTPBP4 GTPBP4 RRP15 RRP15 DDX54 DDX54 NSUN6 NSUN6 NSA2 NSA2 ENSPPAP00000040440 ENSPPAP00000040440 BOP1 BOP1 CEBPZ CEBPZ ENSPPAP00000041825 ENSPPAP00000041825 MRTO4 MRTO4 NOC3L NOC3L NMD3 NMD3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NIP760S ribosome subunit biogenesis protein NIP7 homolog; Required for proper 34S pre-rRNA processing and 60S ribosome subunit assembly; Belongs to the NIP7 family. (180 aa)
GNL2Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily. (794 aa)
LOC100994493Ribosome biogenesis protein NOP53; May play a role in ribosome biogenesis. Belongs to the NOP53 family. (476 aa)
ENSPPAP0000000139560S ribosome subunit biogenesis protein NIP7 homolog; Required for proper 34S pre-rRNA processing and 60S ribosome subunit assembly; Belongs to the NIP7 family. (164 aa)
MDN1Midasin; Nuclear chaperone required for maturation and nuclear export of pre-60S ribosome subunits; Belongs to the midasin family. (5596 aa)
RSL24D1Uncharacterized protein. (71 aa)
GNL3G protein nucleolar 3. (549 aa)
LOC100988174WD_REPEATS_REGION domain-containing protein. (446 aa)
RRS1Ribosome biogenesis regulatory protein; Involved in ribosomal large subunit assembly. Belongs to the RRS1 family. (365 aa)
FTSJ3pre-rRNA processing protein FTSJ3; Probable methyltransferase involved in the processing of the 34S pre-rRNA to 18S rRNA and in 40S ribosomal subunit formation. Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily. (846 aa)
PAK1IP1PAK1 interacting protein 1. (392 aa)
ZNF622Zinc finger protein 622. (477 aa)
UTP23UTP23 small subunit processome component. (249 aa)
ENSPPAP00000010956RRM domain-containing protein. (251 aa)
ENSPPAP00000011414Uncharacterized protein. (249 aa)
RRP1Ribosomal RNA processing 1. (461 aa)
DDX56DEAD-box helicase 56. (556 aa)
PWP1PWP1 homolog, endonuclein. (501 aa)
LSG1Large 60S subunit nuclear export GTPase 1. (658 aa)
ENSPPAP00000012297Ribosome biogenesis protein NOP53; May play a role in ribosome biogenesis. Belongs to the NOP53 family. (453 aa)
ENSPPAP00000012368Uncharacterized protein. (225 aa)
ENSPPAP00000013012Protein SDA1; Required for 60S pre-ribosomal subunits export to the cytoplasm; Belongs to the SDA1 family. (197 aa)
PES1Pescadillo homolog; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome; Belongs to the pescadillo family. (587 aa)
ZNF593Zinc finger protein 593. (134 aa)
NOP2NOP2 nucleolar protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (845 aa)
ENSPPAP00000014695Uncharacterized protein; Belongs to the DEAD box helicase family. (605 aa)
RBM34RNA binding motif protein 34. (422 aa)
EIF6Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Behaves as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (RACK1)- dependent protein kinase C activity. In tissues responsive to insulin, contro [...] (245 aa)
ENSPPAP00000015877Uncharacterized protein. (251 aa)
ENSPPAP00000016348TRASH domain-containing protein. (150 aa)
NLE1Notchless homolog 1. (485 aa)
ENSPPAP00000017938Brix domain-containing protein. (280 aa)
SURF6Surfeit 6. (361 aa)
NOL12Uncharacterized protein. (213 aa)
NOP53Ribosome biogenesis protein NOP53; May play a role in ribosome biogenesis. Belongs to the NOP53 family. (427 aa)
ENSPPAP00000019735RRM domain-containing protein. (240 aa)
LOC100988838Protein SDA1; Required for 60S pre-ribosomal subunits export to the cytoplasm; Belongs to the SDA1 family. (601 aa)
DDX18RNA helicase. (670 aa)
WDR12Ribosome biogenesis protein WDR12; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (433 aa)
GNL3LG protein nucleolar 3 like. (582 aa)
NIFKNucleolar protein interacting with the FHA domain of MKI67. (293 aa)
MAK16Protein MAK16 homolog; Belongs to the MAK16 family. (300 aa)
RRP1BRibosomal RNA processing 1B. (747 aa)
RPF2Ribosome production factor 2 homolog. (306 aa)
NOC2LNOC2 like nucleolar associated transcriptional repressor. (712 aa)
DDX27DEAD-box helicase 27; Belongs to the DEAD box helicase family. (759 aa)
WDR74WD repeat domain 74. (385 aa)
BRIX1Biogenesis of ribosomes BRX1. (353 aa)
EBNA1BP2EBNA1 binding protein 2. (361 aa)
RPF1Ribosome production factor 1 homolog. (349 aa)
DDX24DEAD-box helicase 24. (859 aa)
SDAD1Protein SDA1; Required for 60S pre-ribosomal subunits export to the cytoplasm; Belongs to the SDA1 family. (687 aa)
KCTD19Potassium channel tetramerization domain containing 19. (926 aa)
ENSPPAP00000033416Uncharacterized protein. (208 aa)
RSL1D1Ribosomal L1 domain containing 1. (490 aa)
PPANPeter pan homolog. (473 aa)
ENSPPAP00000034922G domain-containing protein. (487 aa)
ENSPPAP00000035917TRASH domain-containing protein. (182 aa)
ENSPPAP00000036245Uncharacterized protein. (132 aa)
ENSPPAP00000036270RRM domain-containing protein. (244 aa)
ENSPPAP00000036942Uncharacterized protein. (138 aa)
PUM3Pumilio RNA binding family member 3. (648 aa)
RBM28RNA binding motif protein 28. (761 aa)
P2RY11Purinergic receptor P2Y11; Belongs to the G-protein coupled receptor 1 family. (374 aa)
GTPBP4Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily. (634 aa)
RRP15Ribosomal RNA processing 15 homolog. (285 aa)
DDX54ATP-dependent RNA helicase DDX54; Belongs to the DEAD box helicase family. DDX54/DBP10 subfamily. (885 aa)
NSUN6NOP2/Sun RNA methyltransferase 6; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (469 aa)
NSA2NSA2 ribosome biogenesis factor. (260 aa)
ENSPPAP00000040440Uncharacterized protein. (252 aa)
BOP1Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (712 aa)
CEBPZCCAAT enhancer binding protein zeta. (1054 aa)
ENSPPAP00000041825Uncharacterized protein. (372 aa)
MRTO4Ribosome assembly factor mrt4; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes. (239 aa)
NOC3LNucleolar complex protein 3 homolog. (800 aa)
NMD360S ribosomal export protein NMD3; Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit; Belongs to the NMD3 family. (529 aa)
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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