46 items (Pan paniscus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	NIP7	60S ribosome subunit biogenesis protein NIP7 homolog; Required for proper 34S pre-rRNA processing and 60S ribosome subunit assembly; Belongs to the NIP7 family. (180 aa)
	GNL2	Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily. (794 aa)
	ENSPPAP00000001395	60S ribosome subunit biogenesis protein NIP7 homolog; Required for proper 34S pre-rRNA processing and 60S ribosome subunit assembly; Belongs to the NIP7 family. (164 aa)
	GNL3	G protein nucleolar 3. (549 aa)
	LOC100988174	WD_REPEATS_REGION domain-containing protein. (446 aa)
	RRS1	Ribosome biogenesis regulatory protein; Involved in ribosomal large subunit assembly. Belongs to the RRS1 family. (365 aa)
	FTSJ3	pre-rRNA processing protein FTSJ3; Probable methyltransferase involved in the processing of the 34S pre-rRNA to 18S rRNA and in 40S ribosomal subunit formation. Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily. (846 aa)
	ENSPPAP00000010956	RRM domain-containing protein. (251 aa)
	RRP1	Ribosomal RNA processing 1. (461 aa)
	DDX56	DEAD-box helicase 56. (556 aa)
	PWP1	PWP1 homolog, endonuclein. (501 aa)
	PES1	Pescadillo homolog; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome; Belongs to the pescadillo family. (587 aa)
	ZNF593	Zinc finger protein 593. (134 aa)
	NOP2	NOP2 nucleolar protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (845 aa)
	ENSPPAP00000014695	Uncharacterized protein; Belongs to the DEAD box helicase family. (605 aa)
	RBM34	RNA binding motif protein 34. (422 aa)
	ENSPPAP00000016348	TRASH domain-containing protein. (150 aa)
	ENSPPAP00000017938	Brix domain-containing protein. (280 aa)
	ENSPPAP00000019735	RRM domain-containing protein. (240 aa)
	DDX18	RNA helicase. (670 aa)
	WDR12	Ribosome biogenesis protein WDR12; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (433 aa)
	GNL3L	G protein nucleolar 3 like. (582 aa)
	NIFK	Nucleolar protein interacting with the FHA domain of MKI67. (293 aa)
	MAK16	Protein MAK16 homolog; Belongs to the MAK16 family. (300 aa)
	RPF2	Ribosome production factor 2 homolog. (306 aa)
	NOC2L	NOC2 like nucleolar associated transcriptional repressor. (712 aa)
	DDX27	DEAD-box helicase 27; Belongs to the DEAD box helicase family. (759 aa)
	WDR74	WD repeat domain 74. (385 aa)
	BRIX1	Biogenesis of ribosomes BRX1. (353 aa)
	EBNA1BP2	EBNA1 binding protein 2. (361 aa)
	RPF1	Ribosome production factor 1 homolog. (349 aa)
	DDX24	DEAD-box helicase 24. (859 aa)
	ENSPPAP00000033416	Uncharacterized protein. (208 aa)
	RSL1D1	Ribosomal L1 domain containing 1. (490 aa)
	ENSPPAP00000034922	G domain-containing protein. (487 aa)
	ENSPPAP00000036270	RRM domain-containing protein. (244 aa)
	PUM3	Pumilio RNA binding family member 3. (648 aa)
	RBM28	RNA binding motif protein 28. (761 aa)
	GTPBP4	Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily. (634 aa)
	DDX54	ATP-dependent RNA helicase DDX54; Belongs to the DEAD box helicase family. DDX54/DBP10 subfamily. (885 aa)
	NSUN6	NOP2/Sun RNA methyltransferase 6; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (469 aa)
	BOP1	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (712 aa)
	CEBPZ	CCAAT enhancer binding protein zeta. (1054 aa)
	ENSPPAP00000041825	Uncharacterized protein. (372 aa)
	MRTO4	Ribosome assembly factor mrt4; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes. (239 aa)
	NOC3L	Nucleolar complex protein 3 homolog. (800 aa)

Your Current Organism:

Pan paniscus

NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BOP1	BRIX1	ENSPPAP00000040785	ENSPPAP00000030388	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Biogenesis of ribosomes BRX1.	0.981
BOP1	CEBPZ	ENSPPAP00000040785	ENSPPAP00000041497	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	CCAAT enhancer binding protein zeta.	0.931
BOP1	DDX18	ENSPPAP00000040785	ENSPPAP00000020541	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	RNA helicase.	0.969
BOP1	DDX24	ENSPPAP00000040785	ENSPPAP00000031579	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	DEAD-box helicase 24.	0.941
BOP1	DDX27	ENSPPAP00000040785	ENSPPAP00000025449	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	DEAD-box helicase 27; Belongs to the DEAD box helicase family.	0.943
BOP1	DDX54	ENSPPAP00000040785	ENSPPAP00000038920	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	ATP-dependent RNA helicase DDX54; Belongs to the DEAD box helicase family. DDX54/DBP10 subfamily.	0.939
BOP1	DDX56	ENSPPAP00000040785	ENSPPAP00000011895	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	DEAD-box helicase 56.	0.908
BOP1	EBNA1BP2	ENSPPAP00000040785	ENSPPAP00000030562	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	EBNA1 binding protein 2.	0.987
BOP1	ENSPPAP00000001395	ENSPPAP00000040785	ENSPPAP00000001395	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	60S ribosome subunit biogenesis protein NIP7 homolog; Required for proper 34S pre-rRNA processing and 60S ribosome subunit assembly; Belongs to the NIP7 family.	0.925
BOP1	ENSPPAP00000010956	ENSPPAP00000040785	ENSPPAP00000010956	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	RRM domain-containing protein.	0.843
BOP1	ENSPPAP00000014695	ENSPPAP00000040785	ENSPPAP00000014695	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Uncharacterized protein; Belongs to the DEAD box helicase family.	0.969
BOP1	ENSPPAP00000016348	ENSPPAP00000040785	ENSPPAP00000016348	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	TRASH domain-containing protein.	0.801
BOP1	ENSPPAP00000017938	ENSPPAP00000040785	ENSPPAP00000017938	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Brix domain-containing protein.	0.947
BOP1	ENSPPAP00000019735	ENSPPAP00000040785	ENSPPAP00000019735	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	RRM domain-containing protein.	0.843
BOP1	ENSPPAP00000033416	ENSPPAP00000040785	ENSPPAP00000033416	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Uncharacterized protein.	0.958
BOP1	ENSPPAP00000034922	ENSPPAP00000040785	ENSPPAP00000034922	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	G domain-containing protein.	0.970
BOP1	ENSPPAP00000036270	ENSPPAP00000040785	ENSPPAP00000036270	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	RRM domain-containing protein.	0.843
BOP1	ENSPPAP00000041825	ENSPPAP00000040785	ENSPPAP00000041825	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Uncharacterized protein.	0.991
BOP1	FTSJ3	ENSPPAP00000040785	ENSPPAP00000008144	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	pre-rRNA processing protein FTSJ3; Probable methyltransferase involved in the processing of the 34S pre-rRNA to 18S rRNA and in 40S ribosomal subunit formation. Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily.	0.977
BOP1	GNL2	ENSPPAP00000040785	ENSPPAP00000000435	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily.	0.969