(43 nodes) Chemokine receptors bind chemokines network (Pan paniscus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CXCL17	C-X-C motif chemokine ligand 17. (119 aa)
	CCL1	C-C motif chemokine. (96 aa)
	CCL20	C-C motif chemokine. (96 aa)
	CCR2	C-C motif chemokine receptor 2; Belongs to the G-protein coupled receptor 1 family. (374 aa)
	CCL21	C-C motif chemokine ligand 21. (134 aa)
	ACKR3	Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family. (362 aa)
	ACKR4	Atypical chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family. (350 aa)
	CXCR2	C-X-C motif chemokine receptor 2; Belongs to the G-protein coupled receptor 1 family. (360 aa)
	CXCR1	C-X-C motif chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family. (350 aa)
	PF4V1	C-X-C motif chemokine. (104 aa)
	CXCL1	C-X-C motif chemokine. (107 aa)
	CCL25	C-C motif chemokine ligand 25. (150 aa)
	CXCL11	C-X-C motif chemokine. (94 aa)
	CCL2	C-C motif chemokine. (99 aa)
	CCL19	C-C motif chemokine. (98 aa)
	CX3CR1	C-X3-C motif chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family. (387 aa)
	CXCL5	C-X-C motif chemokine. (114 aa)
	CXCR5	C-X-C motif chemokine receptor 5; Belongs to the G-protein coupled receptor 1 family. (372 aa)
	CCL16	C-C motif chemokine. (120 aa)
	CCR10	C-C motif chemokine receptor 10; Belongs to the G-protein coupled receptor 1 family. (362 aa)
	CCR6	C-C motif chemokine receptor 6; Belongs to the G-protein coupled receptor 1 family. (374 aa)
	PF4	C-X-C motif chemokine. (101 aa)
	CX3CL1	C-X3-C motif chemokine ligand 1. (397 aa)
	CXCL6	C-X-C motif chemokine. (114 aa)
	CXCL13	C-X-C motif chemokine. (109 aa)
	CXCL10	C-X-C motif chemokine. (96 aa)
	CXCL2	C-X-C motif chemokine. (107 aa)
	CXCL9	C-X-C motif chemokine. (125 aa)
	CCL8	C-C motif chemokine. (109 aa)
	CXCL14	C-X-C motif chemokine ligand 14. (111 aa)
	CXCL12	SCY domain-containing protein; Belongs to the intercrine alpha (chemokine CxC) family. (119 aa)
	CCL27	C-C motif chemokine ligand 27. (112 aa)
	CCL17	C-C motif chemokine. (94 aa)
	CCL13	C-C motif chemokine. (98 aa)
	CXCR4	C-X-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family. (423 aa)
	CCL11	C-C motif chemokine. (97 aa)
	PPBP	C-X-C motif chemokine. (128 aa)
	CXCR3	C-X-C motif chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family. (368 aa)
	CCR7	C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family. (372 aa)
	CCL28	C-C motif chemokine. (127 aa)
	CCL26	C-C motif chemokine. (94 aa)
	CCR9	C-C motif chemokine receptor 9; Belongs to the G-protein coupled receptor 1 family. (369 aa)
	CCL5	C-C motif chemokine. (91 aa)

Your Current Organism:

Pan paniscus

NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACKR3	CCL13	ENSPPAP00000003168	ENSPPAP00000037358	Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family.	C-C motif chemokine.	0.726
ACKR3	CCL19	ENSPPAP00000003168	ENSPPAP00000020066	Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family.	C-C motif chemokine.	0.513
ACKR3	CCL20	ENSPPAP00000003168	ENSPPAP00000002066	Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family.	C-C motif chemokine.	0.467
ACKR3	CCL21	ENSPPAP00000003168	ENSPPAP00000003129	Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family.	C-C motif chemokine ligand 21.	0.749
ACKR3	CCL25	ENSPPAP00000003168	ENSPPAP00000016337	Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family.	C-C motif chemokine ligand 25.	0.582
ACKR3	CCL27	ENSPPAP00000003168	ENSPPAP00000036276	Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family.	C-C motif chemokine ligand 27.	0.444
ACKR3	CCL5	ENSPPAP00000003168	ENSPPAP00000042652	Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family.	C-C motif chemokine.	0.521
ACKR3	CCR2	ENSPPAP00000003168	ENSPPAP00000002177	Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family.	C-C motif chemokine receptor 2; Belongs to the G-protein coupled receptor 1 family.	0.504
ACKR3	CCR6	ENSPPAP00000003168	ENSPPAP00000025564	Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family.	C-C motif chemokine receptor 6; Belongs to the G-protein coupled receptor 1 family.	0.506
ACKR3	CCR7	ENSPPAP00000003168	ENSPPAP00000039258	Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family.	C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family.	0.497
ACKR3	CX3CL1	ENSPPAP00000003168	ENSPPAP00000026840	Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family.	C-X3-C motif chemokine ligand 1.	0.428
ACKR3	CXCL1	ENSPPAP00000003168	ENSPPAP00000014887	Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family.	C-X-C motif chemokine.	0.479
ACKR3	CXCL10	ENSPPAP00000003168	ENSPPAP00000030363	Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family.	C-X-C motif chemokine.	0.722
ACKR3	CXCL11	ENSPPAP00000003168	ENSPPAP00000016547	Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family.	C-X-C motif chemokine.	0.932
ACKR3	CXCL12	ENSPPAP00000003168	ENSPPAP00000036076	Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family.	SCY domain-containing protein; Belongs to the intercrine alpha (chemokine CxC) family.	0.999
ACKR3	CXCL13	ENSPPAP00000003168	ENSPPAP00000030059	Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family.	C-X-C motif chemokine.	0.438
ACKR3	CXCL2	ENSPPAP00000003168	ENSPPAP00000031371	Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family.	C-X-C motif chemokine.	0.413
ACKR3	CXCL5	ENSPPAP00000003168	ENSPPAP00000022876	Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family.	C-X-C motif chemokine.	0.463
ACKR3	CXCL9	ENSPPAP00000003168	ENSPPAP00000033448	Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family.	C-X-C motif chemokine.	0.707
ACKR3	CXCR1	ENSPPAP00000003168	ENSPPAP00000004941	Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family.	C-X-C motif chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family.	0.528