STRINGSTRING
SOCS5 SOCS5 IFNA14 IFNA14 IFNA6 IFNA6 IL10 IL10 LOC100972005 LOC100972005 IL7 IL7 IFNA5 IFNA5 IFNA10 IFNA10 IL10RB IL10RB IFNA8 IFNA8 MPL MPL IRF9 IRF9 LIF LIF IFNAR1 IFNAR1 JAK1 JAK1 SOCS3 SOCS3 IL20RB IL20RB JAK2 JAK2 IL6ST IL6ST IL23R IL23R IFNL1 IFNL1 CSF3 CSF3 IFNW1 IFNW1 IFNGR2 IFNGR2 IL22 IL22 SOCS7 SOCS7 CSF2RA CSF2RA IL4 IL4 IL20RA IL20RA ENSPPAP00000009354 ENSPPAP00000009354 LOC100983900 LOC100983900 OSM OSM IL20 IL20 IL6R IL6R GH2 GH2 IL12RB2 IL12RB2 STAT6 STAT6 IL2 IL2 IL15RA IL15RA IL26 IL26 IL13RA1 IL13RA1 IL13 IL13 IL31RA IL31RA ENSPPAP00000016834 ENSPPAP00000016834 IL9 IL9 THPO THPO IFNGR1 IFNGR1 IL10RA IL10RA IL31 IL31 IFNA7 IFNA7 OSMR OSMR EPOR EPOR IL3 IL3 IFNAR2 IFNAR2 IL19 IL19 IL9R IL9R CLCF1 CLCF1 IL22RA1 IL22RA1 IL12RB1 IL12RB1 IL2RB IL2RB IL6 IL6 GALT GALT PRL PRL IL24 IL24 GHR GHR IL2RA IL2RA IL12B IL12B IL13RA2 IL13RA2 CSF3R CSF3R TSLP TSLP IL21 IL21 STAT4 STAT4 IL12A IL12A CTF1 CTF1 PTPN2 PTPN2 IFNLR1 IFNLR1 TYK2 TYK2 IL7R IL7R STAT1 STAT1 STAT5B STAT5B LIFR LIFR IL11 IL11 CNTF CNTF IL2RG IL2RG IFNL2 IFNL2 CSF2RB CSF2RB STAT3 STAT3 JAK3 JAK3 CNTFR CNTFR CSF2 CSF2 IL21R IL21R LOC100971425 LOC100971425 IL4R IL4R STAT2 STAT2 IFNG IFNG STAT5A STAT5A EPO EPO IL22RA2 IL22RA2 IL23A IL23A IL15 IL15 IL5 IL5 IL5RA IL5RA PRLR PRLR
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SOCS5Suppressor of cytokine signaling 5. (536 aa)
IFNA14Interferon alpha 14. (189 aa)
IFNA6Interferon alpha 6. (189 aa)
IL10Interleukin 10. (178 aa)
LOC100972005Uncharacterized protein. (198 aa)
IL7Interleukin 7. (179 aa)
IFNA5Interferon alpha 5. (189 aa)
IFNA10Interferon alpha 10. (189 aa)
IL10RBInterleukin 10 receptor subunit beta. (325 aa)
IFNA8Interferon alpha 8. (189 aa)
MPLMPL proto-oncogene, thrombopoietin receptor. (646 aa)
IRF9Interferon regulatory factor 9. (392 aa)
LIFLIF interleukin 6 family cytokine. (202 aa)
IFNAR1Interferon alpha and beta receptor subunit 1. (558 aa)
JAK1Tyrosine-protein kinase. (1153 aa)
SOCS3Suppressor of cytokine signaling 3. (225 aa)
IL20RBInterleukin 20 receptor subunit beta. (281 aa)
JAK2Tyrosine-protein kinase. (1143 aa)
IL6STInterleukin 6 signal transducer. (928 aa)
IL23RInterleukin 23 receptor. (629 aa)
IFNL1Interferon lambda 1. (200 aa)
CSF3Colony stimulating factor 3. (204 aa)
IFNW1Interferon omega 1. (200 aa)
IFNGR2Interferon gamma receptor 2. (347 aa)
IL22Interleukin 22. (179 aa)
SOCS7Suppressor of cytokine signaling 7. (518 aa)
CSF2RAUncharacterized protein. (262 aa)
IL4Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Belongs to the IL-4/IL-13 family. (153 aa)
IL20RAInterleukin 20 receptor subunit alpha. (504 aa)
ENSPPAP00000009354Uncharacterized protein. (185 aa)
LOC100983900Uncharacterized protein. (172 aa)
OSMOncostatin M. (252 aa)
IL20Interleukin 20. (176 aa)
IL6RInterleukin 6 receptor. (468 aa)
GH2Growth hormone 2. (256 aa)
IL12RB2Interleukin 12 receptor subunit beta 2. (740 aa)
STAT6Signal transducer and activator of transcription. (852 aa)
IL2Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. (153 aa)
IL15RASushi domain-containing protein. (278 aa)
IL26Interleukin 26. (171 aa)
IL13RA1Interleukin 13 receptor subunit alpha 1. (426 aa)
IL13Interleukin 13. (146 aa)
IL31RAInterleukin 31 receptor A. (764 aa)
ENSPPAP00000016834Uncharacterized protein. (195 aa)
IL9Interleukin 9. (144 aa)
THPOThrombopoietin. (353 aa)
IFNGR1Interferon gamma receptor 1. (489 aa)
IL10RAInterleukin 10 receptor subunit alpha. (578 aa)
IL31Interleukin 31. (164 aa)
IFNA7Interferon alpha 7. (189 aa)
OSMROncostatin M receptor. (978 aa)
EPORErythropoietin receptor; Receptor for erythropoietin. (508 aa)
IL3Interleukin-3; Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. Belongs to the IL-3 family. (154 aa)
IFNAR2Uncharacterized protein. (519 aa)
IL19Interleukin 19. (217 aa)
IL9RInterleukin 9 receptor. (527 aa)
CLCF1Uncharacterized protein. (322 aa)
IL22RA1Interleukin 22 receptor subunit alpha 1. (574 aa)
IL12RB1Interleukin 12 receptor subunit beta 1. (662 aa)
IL2RBInterleukin 2 receptor subunit beta. (551 aa)
IL6Uncharacterized protein. (198 aa)
GALTUncharacterized protein. (771 aa)
PRLProlactin. (227 aa)
IL24Interleukin 24. (206 aa)
GHRGrowth hormone receptor. (641 aa)
IL2RASushi domain-containing protein. (249 aa)
IL12BInterleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (328 aa)
IL13RA2Interleukin 13 receptor subunit alpha 2. (380 aa)
CSF3RColony stimulating factor 3 receptor. (836 aa)
TSLPThymic stromal lymphopoietin. (159 aa)
IL21Interleukin; Belongs to the IL-15/IL-21 family. (162 aa)
STAT4Signal transducer and activator of transcription. (742 aa)
IL12AInterleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (253 aa)
CTF1Uncharacterized protein. (125 aa)
PTPN2Tyrosine-protein phosphatase non-receptor type. (424 aa)
IFNLR1Interferon lambda receptor 1. (519 aa)
TYK2Tyrosine-protein kinase. (1190 aa)
IL7RInterleukin 7 receptor. (459 aa)
STAT1Signal transducer and activator of transcription. (759 aa)
STAT5BSignal transducer and activator of transcription. (789 aa)
LIFRLIF receptor subunit alpha. (1097 aa)
IL11Interleukin 11. (199 aa)
CNTFCiliary neurotrophic factor. (200 aa)
IL2RGFibronectin type-III domain-containing protein. (369 aa)
IFNL2Interferon lambda 2. (196 aa)
CSF2RBColony stimulating factor 2 receptor beta common subunit. (904 aa)
STAT3Signal transducer and activator of transcription. (781 aa)
JAK3Tyrosine-protein kinase. (1090 aa)
CNTFRCiliary neurotrophic factor receptor. (372 aa)
CSF2Colony stimulating factor 2. (144 aa)
IL21RInterleukin 21 receptor. (538 aa)
LOC100971425Uncharacterized protein. (217 aa)
IL4RInterleukin 4 receptor. (873 aa)
STAT2Signal transducer and activator of transcription. (853 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (166 aa)
STAT5ASignal transducer and activator of transcription. (794 aa)
EPOErythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family. (193 aa)
IL22RA2Interleukin 22 receptor subunit alpha 2. (263 aa)
IL23AInterleukin 23 subunit alpha. (189 aa)
IL15Interleukin; Belongs to the IL-15/IL-21 family. (162 aa)
IL5Interleukin-5; Factor that induces terminal differentiation of late- developing B-cells to immunoglobulin secreting cells. (134 aa)
IL5RAInterleukin 5 receptor subunit alpha. (423 aa)
PRLRProlactin receptor; This is a receptor for the anterior pituitary hormone prolactin. (622 aa)
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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