(96 nodes) Antigen binding, and Antigen processing and presentation network (Pan paniscus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CD36	CD36 molecule; Belongs to the CD36 family. (472 aa)
	HLA-C	Major histocompatibility complex, class I, C; Belongs to the MHC class I family. (397 aa)
	CALR	Calreticulin. (417 aa)
	ENSPPAP00000001730	Ig-like domain-containing protein. (204 aa)
	IGLL1	Ig-like domain-containing protein. (198 aa)
	B2M	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. (119 aa)
	ENSPPAP00000004208	Ig-like domain-containing protein. (134 aa)
	THBS1	Thrombospondin 1. (1173 aa)
	ENSPPAP00000004636	Ig-like domain-containing protein. (131 aa)
	MR1	Major histocompatibility complex, class I-related; Belongs to the MHC class I family. (341 aa)
	LOC100979649	Ig-like domain-containing protein. (170 aa)
	ENSPPAP00000005092	Uncharacterized protein. (582 aa)
	KLRC1	Killer cell lectin like receptor C1. (233 aa)
	TAPBP	TAP binding protein. (466 aa)
	OLR1	Oxidized low density lipoprotein receptor 1. (273 aa)
	ENSPPAP00000007704	Ig-like domain-containing protein. (190 aa)
	LOC100982558	Ig-like domain-containing protein. (151 aa)
	CD47	CD47 molecule. (307 aa)
	HLA-DOB	Major histocompatibility complex, class II, DO beta. (266 aa)
	C2AH2orf74	Uncharacterized protein. (194 aa)
	ENSPPAP00000008696	Ig-like domain-containing protein. (147 aa)
	ENSPPAP00000008850	Ig-like domain-containing protein. (199 aa)
	ENSPPAP00000009176	Ig-like domain-containing protein. (166 aa)
	ENSPPAP00000009285	Ig-like domain-containing protein. (168 aa)
	LOC100993508	Ig-like domain-containing protein; Belongs to the MHC class II family. (255 aa)
	ENSPPAP00000009752	Ig-like domain-containing protein. (138 aa)
	ENSPPAP00000009755	Ig-like domain-containing protein. (116 aa)
	HLA-F	Major histocompatibility complex, class I, F; Belongs to the MHC class I family. (441 aa)
	ENSPPAP00000010626	Ig-like domain-containing protein. (215 aa)
	LOC100987319	Uncharacterized protein. (360 aa)
	SIRPD	Signal regulatory protein delta. (198 aa)
	ENSPPAP00000011261	Ig-like domain-containing protein. (152 aa)
	ENSPPAP00000011445	Ig-like domain-containing protein. (140 aa)
	LOC100990170	Uncharacterized protein. (397 aa)
	IGLV9-49	Immunoglobulin lambda variable 9-49. (123 aa)
	ENSPPAP00000011685	Ig-like domain-containing protein. (178 aa)
	SIRPB1	Uncharacterized protein. (427 aa)
	TAP1	Transporter 1, ATP binding cassette subfamily B member. (808 aa)
	SIRPG	Signal regulatory protein gamma. (354 aa)
	HLA-B	Ig-like domain-containing protein; Belongs to the MHC class I family. (384 aa)
	LOC100986750	Ig-like domain-containing protein. (287 aa)
	SIRPA	Signal regulatory protein alpha. (504 aa)
	PDIA3	Protein disulfide-isomerase. (505 aa)
	HLA-G	Major histocompatibility complex, class I, G; Belongs to the MHC class I family. (355 aa)
	HLA-DPA1	Major histocompatibility complex, class II, DP alpha 1; Belongs to the MHC class II family. (260 aa)
	IGKV2D-29	Immunoglobulin kappa variable 2D-29. (102 aa)
	VPREB3	V-set pre-B cell surrogate light chain 3. (123 aa)
	ENSPPAP00000018569	Ig-like domain-containing protein. (122 aa)
	ENSPPAP00000019256	IGv domain-containing protein. (84 aa)
	KLRC3	C-type lectin domain-containing protein. (240 aa)
	NIBAN3	Niban apoptosis regulator 3. (666 aa)
	Papa-A	IGc1 domain-containing protein; Belongs to the MHC class I family. (406 aa)
	ENSPPAP00000020680	Ig-like domain-containing protein. (160 aa)
	TAP2	Transporter 2, ATP binding cassette subfamily B member. (724 aa)
	ENSPPAP00000023019	IGv domain-containing protein. (93 aa)
	CD4	CD4 molecule. (458 aa)
	ENSPPAP00000023406	Uncharacterized protein. (84 aa)
	JCHAIN	Joining chain of multimeric IgA and IgM. (159 aa)
	PIGR	Polymeric immunoglobulin receptor. (764 aa)
	KLRC4	Uncharacterized protein. (158 aa)
	LOC100992623	Ig-like domain-containing protein. (365 aa)
	HLA-DOA	Major histocompatibility complex, class II, DO alpha; Belongs to the MHC class II family. (250 aa)
	MSR1	Macrophage scavenger receptor 1. (460 aa)
	ENSPPAP00000027145	MHC_II_beta domain-containing protein. (95 aa)
	IL16	Pro-interleukin-16; Interleukin-16 stimulates a migratory response in CD4+ lymphocytes, monocytes, and eosinophils. Primes CD4+ T-cells for IL-2 and IL-15 responsiveness. Also induces T-lymphocyte expression of interleukin 2 receptor. Ligand for CD4. (1378 aa)
	TRAC	T cell receptor alpha constant. (147 aa)
	ENSPPAP00000028799	Ig-like domain-containing protein. (147 aa)
	CD74	CD74 molecule. (296 aa)
	ENSPPAP00000029022	Ig-like domain-containing protein. (161 aa)
	MHC-DMB	Ig-like domain-containing protein. (276 aa)
	HLA-DQA2	Major histocompatibility complex, class II, DQ alpha 2; Belongs to the MHC class II family. (255 aa)
	HLA-E	Major histocompatibility complex, class I, E; Belongs to the MHC class I family. (352 aa)
	MS4A1	Membrane spanning 4-domains A1. (297 aa)
	LOC100993847	Ig-like domain-containing protein. (270 aa)
	CD79A	CD79a molecule. (226 aa)
	ENSPPAP00000031691	Ig-like domain-containing protein. (178 aa)
	ENSPPAP00000031810	MHC_I-like_Ag-recog domain-containing protein. (194 aa)
	FCRL2	Fc receptor like 2. (444 aa)
	FCRL4	Fc receptor like 4. (515 aa)
	ENSPPAP00000032530	Ig-like domain-containing protein. (108 aa)
	LOC100987433	Ig-like domain-containing protein. (232 aa)
	FCRLA	Fc receptor like A. (382 aa)
	THBS2	Thrombospondin 2. (1172 aa)
	CD5	CD5 molecule. (495 aa)
	KIR3DL3	Killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 3. (351 aa)
	CD79B	CD79b molecule. (229 aa)
	HLA-DQB1	Major histocompatibility complex, class II, DQ beta 1. (261 aa)
	HLA-DQB2	Major histocompatibility complex, class II, DQ beta 2. (264 aa)
	HLA-DPB1	Major histocompatibility complex, class II, DP beta 1. (258 aa)
	HLA-DMA	Major histocompatibility complex, class II, DM alpha; Belongs to the MHC class II family. (268 aa)
	CD5L	CD5 molecule like. (347 aa)
	KLRD1	Killer cell lectin like receptor D1. (179 aa)
	LOC100986123	Ig-like domain-containing protein. (154 aa)
	HLA-DRA	Major histocompatibility complex, class II, DR alpha; Belongs to the MHC class II family. (254 aa)
	ENSPPAP00000041662	Ig-like domain-containing protein. (155 aa)
	ABCB9	ATP binding cassette subfamily B member 9. (766 aa)

Your Current Organism:

Pan paniscus

NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABCB9	CALR	ENSPPAP00000042286	ENSPPAP00000001484	ATP binding cassette subfamily B member 9.	Calreticulin.	0.429
ABCB9	PDIA3	ENSPPAP00000042286	ENSPPAP00000015915	ATP binding cassette subfamily B member 9.	Protein disulfide-isomerase.	0.416
ABCB9	TAP2	ENSPPAP00000042286	ENSPPAP00000021773	ATP binding cassette subfamily B member 9.	Transporter 2, ATP binding cassette subfamily B member.	0.965
ABCB9	TAPBP	ENSPPAP00000042286	ENSPPAP00000006179	ATP binding cassette subfamily B member 9.	TAP binding protein.	0.736
B2M	CALR	ENSPPAP00000004081	ENSPPAP00000001484	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.	Calreticulin.	0.856
B2M	CD4	ENSPPAP00000004081	ENSPPAP00000023068	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.	CD4 molecule.	0.736
B2M	CD47	ENSPPAP00000004081	ENSPPAP00000007759	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.	CD47 molecule.	0.571
B2M	CD74	ENSPPAP00000004081	ENSPPAP00000028894	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.	CD74 molecule.	0.504
B2M	ENSPPAP00000010626	ENSPPAP00000004081	ENSPPAP00000010626	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.	Ig-like domain-containing protein.	0.759
B2M	ENSPPAP00000027145	ENSPPAP00000004081	ENSPPAP00000027145	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.	MHC_II_beta domain-containing protein.	0.447
B2M	ENSPPAP00000031810	ENSPPAP00000004081	ENSPPAP00000031810	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.	MHC_I-like_Ag-recog domain-containing protein.	0.963
B2M	ENSPPAP00000041662	ENSPPAP00000004081	ENSPPAP00000041662	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.	Ig-like domain-containing protein.	0.849
B2M	HLA-B	ENSPPAP00000004081	ENSPPAP00000013105	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.	Ig-like domain-containing protein; Belongs to the MHC class I family.	0.976
B2M	HLA-C	ENSPPAP00000004081	ENSPPAP00000001437	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.	Major histocompatibility complex, class I, C; Belongs to the MHC class I family.	0.998
B2M	HLA-DMA	ENSPPAP00000004081	ENSPPAP00000037807	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.	Major histocompatibility complex, class II, DM alpha; Belongs to the MHC class II family.	0.546
B2M	HLA-DOA	ENSPPAP00000004081	ENSPPAP00000026518	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.	Major histocompatibility complex, class II, DO alpha; Belongs to the MHC class II family.	0.587
B2M	HLA-DOB	ENSPPAP00000004081	ENSPPAP00000008383	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.	Major histocompatibility complex, class II, DO beta.	0.603
B2M	HLA-DPA1	ENSPPAP00000004081	ENSPPAP00000017558	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.	Major histocompatibility complex, class II, DP alpha 1; Belongs to the MHC class II family.	0.575
B2M	HLA-DPB1	ENSPPAP00000004081	ENSPPAP00000037402	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.	Major histocompatibility complex, class II, DP beta 1.	0.603
B2M	HLA-DQA2	ENSPPAP00000004081	ENSPPAP00000029994	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.	Major histocompatibility complex, class II, DQ alpha 2; Belongs to the MHC class II family.	0.565