STRINGSTRING
TRAF2 TRAF2 BIRC2 BIRC2 TNFRSF1A TNFRSF1A IKBKG IKBKG RIPK1 RIPK1 TAB1 TAB1 MAP3K7 MAP3K7 RNF31 RNF31 NOD1 NOD1 BIRC3 BIRC3 TAB2 TAB2 TAB3 TAB3 TRAF5 TRAF5 RBCK1 RBCK1 TRADD TRADD SHARPIN SHARPIN MAP3K14 MAP3K14 TRAF1 TRAF1 TRAF6 TRAF6 NOD2 NOD2 RIPK2 RIPK2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TRAF2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (501 aa)
BIRC2Baculoviral IAP repeat containing 2. (618 aa)
TNFRSF1ATNF receptor superfamily member 1A. (455 aa)
IKBKGInhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (416 aa)
RIPK1Receptor interacting serine/threonine kinase 1. (805 aa)
TAB1TGF-beta activated kinase 1 (MAP3K7) binding protein 1. (508 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa)
RNF31Uncharacterized protein. (1072 aa)
NOD1Nucleotide binding oligomerization domain containing 1. (953 aa)
BIRC3Baculoviral IAP repeat containing 3. (604 aa)
TAB2TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (693 aa)
TAB3TGF-beta activated kinase 1 (MAP3K7) binding protein 3. (712 aa)
TRAF5TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (557 aa)
RBCK1RANBP2-type and C3HC4-type zinc finger containing 1. (510 aa)
TRADDTNFRSF1A associated via death domain. (311 aa)
SHARPINSHANK associated RH domain interactor. (387 aa)
MAP3K14Mitogen-activated protein kinase kinase kinase 14. (947 aa)
TRAF1TNF receptor-associated factor. (416 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (522 aa)
NOD2Nucleotide binding oligomerization domain containing 2. (1040 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (551 aa)
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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