(93 nodes) ECM-receptor interaction, and Collagen biosynthesis and modifying enzymes network (Pan paniscus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	C1QTNF7	C1q and TNF related 7. (299 aa)
	COL1A1	Collagen type I alpha 1 chain. (1463 aa)
	COL4A6	Collagen type IV alpha 6 chain. (1705 aa)
	COL28A1	Collagen type XXVIII alpha 1 chain. (1125 aa)
	ENSPPAP00000003370	Uncharacterized protein. (1515 aa)
	LAMA3	Laminin subunit alpha 3. (3333 aa)
	COL6A5	Collagen type VI alpha 5 chain. (2598 aa)
	ITGB4	Integrin beta. (1821 aa)
	DST	Uncharacterized protein. (7445 aa)
	COLGALT2	Collagen beta(1-O)galactosyltransferase 2. (636 aa)
	COL4A1	Collagen type IV alpha 1 chain. (1669 aa)
	COL2A1	Uncharacterized protein. (1313 aa)
	ITGA6	Integrin subunit alpha 6; Belongs to the integrin alpha chain family. (1096 aa)
	ITGA9	Integrin subunit alpha 9; Belongs to the integrin alpha chain family. (1020 aa)
	COL25A1	Collagen type XXV alpha 1 chain. (654 aa)
	LOC100981320	Uncharacterized protein. (231 aa)
	COL6A1	Collagen type VI alpha 1 chain. (1015 aa)
	LAMB3	Laminin subunit beta 3. (1171 aa)
	LAMB1	Laminin subunit beta 1. (1786 aa)
	LAMA2	Laminin subunit alpha 2. (3122 aa)
	COL6A2	Collagen type VI alpha 2 chain. (998 aa)
	COL26A1	Collagen type XXVI alpha 1 chain. (388 aa)
	ITGB3	Integrin beta; Belongs to the integrin beta chain family. (814 aa)
	CD151	Tetraspanin. (253 aa)
	ITGA10	Integrin subunit alpha 10; Belongs to the integrin alpha chain family. (1167 aa)
	ITGA11	Integrin subunit alpha 11; Belongs to the integrin alpha chain family. (1178 aa)
	LAMA5	Laminin subunit alpha 5. (3648 aa)
	COL5A2	Collagen type V alpha 2 chain. (1499 aa)
	ITGA8	Integrin subunit alpha 8; Belongs to the integrin alpha chain family. (1063 aa)
	COL4A3	Collagen type IV alpha 3 chain. (1641 aa)
	LAMA1	Laminin subunit alpha 1. (3104 aa)
	EMID1	EMI domain containing 1. (437 aa)
	COL9A3	Collagen type IX alpha 3 chain. (657 aa)
	COL4A2	Collagen type IV alpha 2 chain. (1711 aa)
	ENSPPAP00000017012	Uncharacterized protein. (1199 aa)
	COL3A1	Collagen type III alpha 1 chain. (1465 aa)
	COL27A1	Collagen type XXVII alpha 1 chain. (1838 aa)
	COL15A1	Collagen type XV alpha 1 chain. (1388 aa)
	PPIB	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (216 aa)
	FREM2	FRAS1 related extracellular matrix 2. (3169 aa)
	TNC	Tenascin C. (2201 aa)
	ITGA3	Integrin subunit alpha 3; Belongs to the integrin alpha chain family. (1066 aa)
	LAMC1	Laminin subunit gamma 1. (1609 aa)
	PCSK4	Proprotein convertase subtilisin/kexin type 4. (718 aa)
	LAMC3	Laminin subunit gamma 3. (1559 aa)
	FREM1	FRAS1 related extracellular matrix 1. (2179 aa)
	LAMB2	Laminin subunit beta 2. (1780 aa)
	TNR	Tenascin R. (1360 aa)
	PLOD1	Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1. (737 aa)
	ENSPPAP00000023887	LAM_G_DOMAIN domain-containing protein. (932 aa)
	MATN3	Matrilin 3. (486 aa)
	COL11A1	Collagen type XI alpha 1 chain. (1818 aa)
	LAMC2	Laminin subunit gamma 2. (1193 aa)
	COL4A5	Collagen type IV alpha 5 chain. (1664 aa)
	PEAR1	Platelet endothelial aggregation receptor 1. (1029 aa)
	ITGAV	Integrin subunit alpha V; Belongs to the integrin alpha chain family. (1048 aa)
	COL9A1	Collagen type IX alpha 1 chain. (921 aa)
	ITGA7	Integrin subunit alpha 7; Belongs to the integrin alpha chain family. (1181 aa)
	COLGALT1	Collagen beta(1-O)galactosyltransferase 1. (621 aa)
	ITGA4	Integrin subunit alpha 4; Belongs to the integrin alpha chain family. (1032 aa)
	P3H3	Prolyl 3-hydroxylase 3. (647 aa)
	VTN	Vitronectin. (478 aa)
	COL4A4	Collagen type IV alpha 4 chain. (1690 aa)
	ITGB7	Integrin beta; Belongs to the integrin beta chain family. (802 aa)
	COL6A6	Collagen type VI alpha 6 chain. (2241 aa)
	COL6A3	Uncharacterized protein. (2527 aa)
	PLOD3	Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3. (738 aa)
	ITGB1	Integrin beta; Belongs to the integrin beta chain family. (801 aa)
	COL22A1	VWFA domain-containing protein. (1476 aa)
	LAMA4	Laminin subunit alpha 4. (1823 aa)
	PLOD2	Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2. (758 aa)
	TNN	Tenascin N. (1299 aa)
	CRTAP	Cartilage associated protein. (343 aa)
	ITGA2B	Integrin subunit alpha 2b; Belongs to the integrin alpha chain family. (1039 aa)
	P3H2	Prolyl 3-hydroxylase 2. (636 aa)
	COMP	Cartilage oligomeric matrix protein. (762 aa)
	ITGA5	Integrin subunit alpha 5; Belongs to the integrin alpha chain family. (1046 aa)
	ITGB6	Integrin beta; Belongs to the integrin beta chain family. (788 aa)
	P3H1	Prolyl 3-hydroxylase 1. (797 aa)
	FN1	Fibronectin 1. (2477 aa)
	COL23A1	Collagen type XXIII alpha 1 chain. (457 aa)
	SERPINH1	SERPIN domain-containing protein; Belongs to the serpin family. (215 aa)
	FRAS1	Fraser extracellular matrix complex subunit 1. (4012 aa)
	PLEC	Plectin. (4523 aa)
	COL1A2	Collagen type I alpha 2 chain. (1274 aa)
	COL9A2	Collagen type IX alpha 2 chain. (689 aa)
	PPIC	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (212 aa)
	COL5A1	Collagen type V alpha 1 chain. (1821 aa)
	COL5A3	Collagen type V alpha 3 chain. (1663 aa)
	TSPAN11	Tetraspanin. (260 aa)
	ITGB8	Integrin beta; Belongs to the integrin beta chain family. (757 aa)
	ITGA2	Integrin subunit alpha 2; Belongs to the integrin alpha chain family. (1181 aa)
	COL12A1	Collagen type XII alpha 1 chain. (2982 aa)

Your Current Organism:

Pan paniscus

NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C1QTNF7	COL1A1	ENSPPAP00000000289	ENSPPAP00000000478	C1q and TNF related 7.	Collagen type I alpha 1 chain.	0.400
C1QTNF7	COL2A1	ENSPPAP00000000289	ENSPPAP00000007836	C1q and TNF related 7.	Uncharacterized protein.	0.505
C1QTNF7	PLOD3	ENSPPAP00000000289	ENSPPAP00000030909	C1q and TNF related 7.	Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3.	0.422
C1QTNF7	SERPINH1	ENSPPAP00000000289	ENSPPAP00000037467	C1q and TNF related 7.	SERPIN domain-containing protein; Belongs to the serpin family.	0.418
CD151	COL4A3	ENSPPAP00000014658	ENSPPAP00000016010	Tetraspanin.	Collagen type IV alpha 3 chain.	0.528
CD151	COL4A4	ENSPPAP00000014658	ENSPPAP00000029053	Tetraspanin.	Collagen type IV alpha 4 chain.	0.537
CD151	COL4A5	ENSPPAP00000014658	ENSPPAP00000025037	Tetraspanin.	Collagen type IV alpha 5 chain.	0.530
CD151	DST	ENSPPAP00000014658	ENSPPAP00000005809	Tetraspanin.	Uncharacterized protein.	0.860
CD151	ENSPPAP00000003370	ENSPPAP00000014658	ENSPPAP00000003370	Tetraspanin.	Uncharacterized protein.	0.538
CD151	ENSPPAP00000017012	ENSPPAP00000014658	ENSPPAP00000017012	Tetraspanin.	Uncharacterized protein.	0.867
CD151	ITGA2B	ENSPPAP00000014658	ENSPPAP00000033940	Tetraspanin.	Integrin subunit alpha 2b; Belongs to the integrin alpha chain family.	0.403
CD151	ITGA3	ENSPPAP00000014658	ENSPPAP00000021275	Tetraspanin.	Integrin subunit alpha 3; Belongs to the integrin alpha chain family.	0.966
CD151	ITGA4	ENSPPAP00000014658	ENSPPAP00000026707	Tetraspanin.	Integrin subunit alpha 4; Belongs to the integrin alpha chain family.	0.439
CD151	ITGA5	ENSPPAP00000014658	ENSPPAP00000036715	Tetraspanin.	Integrin subunit alpha 5; Belongs to the integrin alpha chain family.	0.702
CD151	ITGA6	ENSPPAP00000014658	ENSPPAP00000007864	Tetraspanin.	Integrin subunit alpha 6; Belongs to the integrin alpha chain family.	0.853
CD151	ITGA7	ENSPPAP00000014658	ENSPPAP00000026159	Tetraspanin.	Integrin subunit alpha 7; Belongs to the integrin alpha chain family.	0.535
CD151	ITGA8	ENSPPAP00000014658	ENSPPAP00000015920	Tetraspanin.	Integrin subunit alpha 8; Belongs to the integrin alpha chain family.	0.403
CD151	ITGAV	ENSPPAP00000014658	ENSPPAP00000025683	Tetraspanin.	Integrin subunit alpha V; Belongs to the integrin alpha chain family.	0.489
CD151	ITGB1	ENSPPAP00000014658	ENSPPAP00000031658	Tetraspanin.	Integrin beta; Belongs to the integrin beta chain family.	0.897
CD151	ITGB3	ENSPPAP00000014658	ENSPPAP00000014470	Tetraspanin.	Integrin beta; Belongs to the integrin beta chain family.	0.569