STRINGSTRING
ENSPPAP00000000334 ENSPPAP00000000334 VPS36 VPS36 CHMP3 CHMP3 UEVLD UEVLD VTA1 VTA1 CHMP4B CHMP4B PDCD6IP PDCD6IP LOC100979126 LOC100979126 CHMP6 CHMP6 SNF8 SNF8 CHMP1A CHMP1A CHMP2B CHMP2B ENSPPAP00000018201 ENSPPAP00000018201 TSG101 TSG101 VPS37C VPS37C VPS4B VPS4B ENSPPAP00000021469 ENSPPAP00000021469 VPS25 VPS25 CHMP5 CHMP5 ENSPPAP00000023303 ENSPPAP00000023303 VPS37A VPS37A LEMD2 LEMD2 ENSPPAP00000025495 ENSPPAP00000025495 MDP1 MDP1 MVB12A MVB12A SPAST SPAST VPS37B VPS37B MVB12B MVB12B ENSPPAP00000032344 ENSPPAP00000032344 BROX BROX RHPN2 RHPN2 CHMP2A CHMP2A VPS37D VPS37D CHMP4C CHMP4C CHMP4A CHMP4A LOC103784663 LOC103784663 VPS28 VPS28 IST1 IST1 ZFYVE1 ZFYVE1 CHMP7 CHMP7
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSPPAP00000000334Uncharacterized protein. (197 aa)
VPS36Vacuolar protein sorting 36 homolog. (328 aa)
CHMP3Charged multivesicular body protein 3. (222 aa)
UEVLDUEV and lactate/malate dehyrogenase domains. (471 aa)
VTA1Vesicle trafficking 1. (307 aa)
CHMP4BCharged multivesicular body protein 4B. (219 aa)
PDCD6IPBRO1 domain-containing protein. (876 aa)
LOC100979126Uncharacterized protein; Belongs to the AAA ATPase family. (462 aa)
CHMP6Uncharacterized protein. (224 aa)
SNF8Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family. (258 aa)
CHMP1ACharged multivesicular body protein 1A. (196 aa)
CHMP2BCharged multivesicular body protein 2B. (213 aa)
ENSPPAP00000018201Uncharacterized protein. (201 aa)
TSG101Tumor susceptibility 101. (390 aa)
VPS37CVPS37C subunit of ESCRT-I. (355 aa)
VPS4BVacuolar protein sorting 4 homolog B; Belongs to the AAA ATPase family. (446 aa)
ENSPPAP00000021469Uncharacterized protein. (233 aa)
VPS25Vacuolar protein sorting 25 homolog. (176 aa)
CHMP5Charged multivesicular body protein 5. (219 aa)
ENSPPAP00000023303VPS37 C-terminal domain-containing protein. (367 aa)
VPS37AVPS37A subunit of ESCRT-I. (397 aa)
LEMD2MSC domain-containing protein. (201 aa)
ENSPPAP00000025495Uncharacterized protein. (325 aa)
MDP1Magnesium dependent phosphatase 1. (164 aa)
MVB12AMultivesicular body subunit 12A. (273 aa)
SPASTSpastin; ATP-dependent microtubule severing protein that specifically recognizes and cuts microtubules that are polyglutamylated. Preferentially recognizes and acts on microtubules decorated with short polyglutamate tails: severing activity increases as the number of glutamates per tubulin rises from one to eight, but decreases beyond this glutamylation threshold. Severing activity is not dependent on tubulin acetylation or detyrosination. Microtubule severing promotes reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation [...] (602 aa)
VPS37BVPS37B subunit of ESCRT-I. (285 aa)
MVB12BMultivesicular body subunit 12B. (288 aa)
ENSPPAP00000032344Uncharacterized protein. (108 aa)
BROXBRO1 domain and CAAX motif containing. (411 aa)
RHPN2Rhophilin Rho GTPase binding protein 2. (638 aa)
CHMP2ACharged multivesicular body protein 2A. (222 aa)
VPS37DVPS37D subunit of ESCRT-I. (259 aa)
CHMP4CCharged multivesicular body protein 4C. (233 aa)
CHMP4ATransmembrane 9 superfamily member; Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family. (815 aa)
LOC103784663Uncharacterized protein. (201 aa)
VPS28Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process. (221 aa)
IST1IST1 factor associated with ESCRT-III. (374 aa)
ZFYVE1Zinc finger FYVE-type containing 1. (789 aa)
CHMP7Charged multivesicular body protein 7. (453 aa)
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.