STRINGSTRING
TMX2 TMX2 ENSPPAP00000000113 ENSPPAP00000000113 DNAJA3 DNAJA3 AIPL1 AIPL1 DNAJB8 DNAJB8 FKBP4 FKBP4 HYOU1 HYOU1 LOC100969109 LOC100969109 ENSPPAP00000002562 ENSPPAP00000002562 HSPA1L HSPA1L DNAJC3 DNAJC3 DNAJA2 DNAJA2 HSPH1 HSPH1 ENSPPAP00000003058 ENSPPAP00000003058 LOC100991504 LOC100991504 GRPEL1 GRPEL1 MANF MANF HSPA14 HSPA14 CRELD2 CRELD2 ENSPPAP00000003490 ENSPPAP00000003490 SNTN SNTN PDILT PDILT CLPB CLPB ENSPPAP00000004324 ENSPPAP00000004324 C20orf85 C20orf85 LOC100980724 LOC100980724 DNAJC22 DNAJC22 MYORG MYORG C10orf71 C10orf71 MOGS MOGS LOC100982477 LOC100982477 ENSPPAP00000005988 ENSPPAP00000005988 AHSA1 AHSA1 CEBPG CEBPG LOC100995461 LOC100995461 ATF6 ATF6 TRAP1 TRAP1 ENSPPAP00000007277 ENSPPAP00000007277 AIP AIP PDIA5 PDIA5 DNAJA1 DNAJA1 ENSPPAP00000008853 ENSPPAP00000008853 DNAJC6 DNAJC6 BAG1 BAG1 DNAJC1 DNAJC1 ANKRD45 ANKRD45 STUB1 STUB1 XBP1 XBP1 ENSPPAP00000010011 ENSPPAP00000010011 PDIA2 PDIA2 EDEM1 EDEM1 ENSPPAP00000010524 ENSPPAP00000010524 NKTR NKTR TMX3 TMX3 PDIA6 PDIA6 HSPA4L HSPA4L TMEM59L TMEM59L LOC100983911 LOC100983911 ATF3 ATF3 AHR AHR DNAJC2 DNAJC2 SELENOM SELENOM DNAJB1 DNAJB1 LOC100980635 LOC100980635 TMX4 TMX4 ENSPPAP00000015368 ENSPPAP00000015368 ERN1 ERN1 LOC100992830 LOC100992830 PDIA4 PDIA4 HSCB HSCB ENSPPAP00000016619 ENSPPAP00000016619 DNAJB9 DNAJB9 AGR3 AGR3 ENSPPAP00000017043 ENSPPAP00000017043 ATF5 ATF5 NR3C2 NR3C2 C9orf24 C9orf24 TXNDC11 TXNDC11 DNAJC7 DNAJC7 GRPEL2 GRPEL2 ENSPPAP00000018272 ENSPPAP00000018272 MYCBP MYCBP AARSD1 AARSD1 HSPB8 HSPB8 ENSPPAP00000019455 ENSPPAP00000019455 HSBP1L1 HSBP1L1 HSP90AB1 HSP90AB1 ENSPPAP00000020036 ENSPPAP00000020036 ENSPPAP00000020286 ENSPPAP00000020286 ENSPPAP00000020911 ENSPPAP00000020911 PLAAT4 PLAAT4 ENSPPAP00000021314 ENSPPAP00000021314 HSF2 HSF2 ENSPPAP00000021568 ENSPPAP00000021568 CANX CANX DDIT3 DDIT3 DNAJB14 DNAJB14 MYDGF MYDGF EIF2AK2 EIF2AK2 ENSPPAP00000023263 ENSPPAP00000023263 MLF2 MLF2 SELENOF SELENOF P4HTM P4HTM DNAJC5G DNAJC5G DNAJB4 DNAJB4 LOC100977183 LOC100977183 P4HB P4HB SDF2L1 SDF2L1 PRKCSH PRKCSH PPP5D1 PPP5D1 ERO1A ERO1A EDEM2 EDEM2 ENSPPAP00000025633 ENSPPAP00000025633 DNAJA4 DNAJA4 ENSPPAP00000025878 ENSPPAP00000025878 DNAJB12 DNAJB12 SECISBP2L SECISBP2L UGGT2 UGGT2 HSF4 HSF4 CD164 CD164 LOC100987269 LOC100987269 RABL3 RABL3 HSPA2 HSPA2 LOC100981595 LOC100981595 ENSPPAP00000028140 ENSPPAP00000028140 ERN2 ERN2 DNAJB6 DNAJB6 LDLRAD1 LDLRAD1 EDEM3 EDEM3 AGR2 AGR2 HIKESHI HIKESHI STK40 STK40 LONP1 LONP1 HERPUD1 HERPUD1 SIL1 SIL1 ENSPPAP00000030902 ENSPPAP00000030902 ERP27 ERP27 PPP5C PPP5C CDC37L1 CDC37L1 ENSPPAP00000031383 ENSPPAP00000031383 TXNDC5 TXNDC5 ENSPPAP00000031464 ENSPPAP00000031464 EIF2AK1 EIF2AK1 TMX1 TMX1 EIF2AK3 EIF2AK3 ENSPPAP00000031897 ENSPPAP00000031897 SDF2 SDF2 HSPD1 HSPD1 HSPBP1 HSPBP1 HSP90B1 HSP90B1 PRDX4 PRDX4 HSP90AA1 HSP90AA1 NR3C1 NR3C1 UGGT1 UGGT1 ATF4 ATF4 ENSPPAP00000033303 ENSPPAP00000033303 BAG2 BAG2 APOL6 APOL6 CALR3 CALR3 ENSPPAP00000033816 ENSPPAP00000033816 ENSPPAP00000034420 ENSPPAP00000034420 ENSPPAP00000034525 ENSPPAP00000034525 TTC28 TTC28 FKBP5 FKBP5 ENSPPAP00000034683 ENSPPAP00000034683 CLGN CLGN DNAJC10 DNAJC10 CLPX CLPX DNAJC25 DNAJC25 ENSPPAP00000036018 ENSPPAP00000036018 ENSPPAP00000036022 ENSPPAP00000036022 CLPP CLPP HSPA8 HSPA8 ENSPPAP00000036589 ENSPPAP00000036589 DNAJC9 DNAJC9 DNAJB5 DNAJB5 LOC100992102 LOC100992102 EIF2S1 EIF2S1 CDC37 CDC37 HSPA4 HSPA4 ERP29 ERP29 SCCPDH SCCPDH DNAJB11 DNAJB11 SUGT1 SUGT1 STIP1 STIP1 DNAJC5B DNAJC5B BAG3 BAG3 HSPA5 HSPA5 USP33 USP33 GANAB GANAB LOC100975678 LOC100975678 ENSPPAP00000041535 ENSPPAP00000041535 TOMM34 TOMM34 ERO1B ERO1B HSPA9 HSPA9 ENSPPAP00000042396 ENSPPAP00000042396 EIF2A EIF2A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TMX2Thioredoxin related transmembrane protein 2. (296 aa)
ENSPPAP00000000113Uncharacterized protein; Belongs to the TCP-1 chaperonin family. (253 aa)
DNAJA3DnaJ heat shock protein family (Hsp40) member A3. (480 aa)
AIPL1Aryl-hydrocarbon-interacting protein-like 1; May be important in protein trafficking and/or protein folding and stabilization. (374 aa)
DNAJB8DnaJ heat shock protein family (Hsp40) member B8. (232 aa)
FKBP4Peptidylprolyl isomerase. (456 aa)
HYOU1Hypoxia up-regulated 1. (999 aa)
LOC100969109Uncharacterized protein. (463 aa)
ENSPPAP00000002562BZIP domain-containing protein. (314 aa)
HSPA1LHeat shock protein family A (Hsp70) member 1 like; Belongs to the heat shock protein 70 family. (641 aa)
DNAJC3DnaJ heat shock protein family (Hsp40) member C3. (497 aa)
DNAJA2DnaJ heat shock protein family (Hsp40) member A2. (412 aa)
HSPH1Heat shock protein family H (Hsp110) member 1. (842 aa)
ENSPPAP00000003058TPR_REGION domain-containing protein. (207 aa)
LOC100991504Uncharacterized protein; Belongs to the heat shock protein 70 family. (581 aa)
GRPEL1GrpE protein homolog; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the GrpE family. (217 aa)
MANFMesencephalic astrocyte derived neurotrophic factor. (182 aa)
HSPA14Heat shock protein family A (Hsp70) member 14; Belongs to the heat shock protein 70 family. (509 aa)
CRELD2Cysteine rich with EGF like domains 2. (364 aa)
ENSPPAP00000003490Uncharacterized protein. (117 aa)
SNTNS_100 domain-containing protein. (166 aa)
PDILTProtein disulfide isomerase like, testis expressed. (584 aa)
CLPBClpB homolog, mitochondrial AAA ATPase chaperonin. (704 aa)
ENSPPAP00000004324J domain-containing protein. (105 aa)
C20orf85Chromosome 20 open reading frame 85. (152 aa)
LOC100980724BZIP domain-containing protein. (359 aa)
DNAJC22DnaJ heat shock protein family (Hsp40) member C22. (341 aa)
MYORGMyogenesis regulating glycosidase (putative); Belongs to the glycosyl hydrolase 31 family. (714 aa)
C10orf71Chromosome 10 open reading frame 71. (1289 aa)
MOGSMannosyl-oligosaccharide glucosidase. (837 aa)
LOC100982477Uncharacterized protein; Belongs to the GroES chaperonin family. (126 aa)
ENSPPAP00000005988Uncharacterized protein. (469 aa)
AHSA1Activator of HSP90 ATPase activity 1. (338 aa)
CEBPGCCAAT enhancer binding protein gamma. (150 aa)
LOC100995461Uncharacterized protein. (307 aa)
ATF6Activating transcription factor 6. (670 aa)
TRAP1TNF receptor associated protein 1. (673 aa)
ENSPPAP00000007277Uncharacterized protein. (321 aa)
AIPPeptidylprolyl isomerase. (330 aa)
PDIA5Protein disulfide isomerase family A member 5. (519 aa)
DNAJA1DnaJ heat shock protein family (Hsp40) member A1. (397 aa)
ENSPPAP00000008853Uncharacterized protein; Belongs to the heat shock protein 70 family. (617 aa)
DNAJC6DnaJ heat shock protein family (Hsp40) member C6. (962 aa)
BAG1BCL2 associated athanogene 1. (345 aa)
DNAJC1DnaJ heat shock protein family (Hsp40) member C1. (559 aa)
ANKRD45ANK_REP_REGION domain-containing protein. (266 aa)
STUB1STIP1 homology and U-box containing protein 1. (303 aa)
XBP1BZIP domain-containing protein. (380 aa)
ENSPPAP00000010011Uncharacterized protein; Belongs to the TCP-1 chaperonin family. (238 aa)
PDIA2Protein disulfide isomerase family A member 2. (525 aa)
EDEM1alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (592 aa)
ENSPPAP00000010524TPR_REGION domain-containing protein. (319 aa)
NKTRNatural killer cell triggering receptor. (1347 aa)
TMX3Thioredoxin related transmembrane protein 3. (454 aa)
PDIA6Protein disulfide isomerase family A member 6; Belongs to the protein disulfide isomerase family. (505 aa)
HSPA4LHeat shock protein family A (Hsp70) member 4 like. (948 aa)
TMEM59LTransmembrane protein 59 like. (324 aa)
LOC100983911BZIP domain-containing protein. (318 aa)
ATF3Activating transcription factor 3. (181 aa)
AHRUncharacterized protein. (850 aa)
DNAJC2DnaJ heat shock protein family (Hsp40) member C2. (620 aa)
SELENOMSelenoprotein M. (124 aa)
DNAJB1DnaJ heat shock protein family (Hsp40) member B1. (367 aa)
LOC100980635Uncharacterized protein. (361 aa)
TMX4Thioredoxin related transmembrane protein 4. (359 aa)
ENSPPAP00000015368Uncharacterized protein; Belongs to the heat shock protein 70 family. (630 aa)
ERN1Endoplasmic reticulum to nucleus signaling 1. (977 aa)
LOC100992830HATPase_c domain-containing protein. (584 aa)
PDIA4Protein disulfide-isomerase A4. (645 aa)
HSCBHscB mitochondrial iron-sulfur cluster cochaperone. (235 aa)
ENSPPAP00000016619Uncharacterized protein; Belongs to the heat shock protein 70 family. (564 aa)
DNAJB9DnaJ heat shock protein family (Hsp40) member B9. (223 aa)
AGR3Anterior gradient 3, protein disulphide isomerase family member. (166 aa)
ENSPPAP00000017043Peptidylprolyl isomerase. (371 aa)
ATF5Activating transcription factor 5. (281 aa)
NR3C2Nuclear receptor subfamily 3 group C member 2. (937 aa)
C9orf24Chromosome 9 open reading frame 24. (262 aa)
TXNDC11Thioredoxin domain containing 11. (956 aa)
DNAJC7DnaJ heat shock protein family (Hsp40) member C7. (438 aa)
GRPEL2GrpE protein homolog; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the GrpE family. (225 aa)
ENSPPAP00000018272Uncharacterized protein. (549 aa)
MYCBPUncharacterized protein. (56 aa)
AARSD1Uncharacterized protein. (586 aa)
HSPB8Heat shock protein family B (small) member 8; Belongs to the small heat shock protein (HSP20) family. (196 aa)
ENSPPAP00000019455Uncharacterized protein. (297 aa)
HSBP1L1Uncharacterized protein. (57 aa)
HSP90AB1HATPase_c domain-containing protein. (688 aa)
ENSPPAP00000020036J domain-containing protein. (204 aa)
ENSPPAP00000020286Uncharacterized protein. (159 aa)
ENSPPAP00000020911J domain-containing protein. (148 aa)
PLAAT4Phospholipase A and acyltransferase 4. (164 aa)
ENSPPAP00000021314Uncharacterized protein. (298 aa)
HSF2Heat shock transcription factor 2. (536 aa)
ENSPPAP00000021568Uncharacterized protein; Belongs to the GroES chaperonin family. (91 aa)
CANXCalnexin. (592 aa)
DDIT3DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (169 aa)
DNAJB14DnaJ heat shock protein family (Hsp40) member B14. (439 aa)
MYDGFMyeloid derived growth factor. (173 aa)
EIF2AK2Eukaryotic translation initiation factor 2-alpha kinase 2. (552 aa)
ENSPPAP00000023263Uncharacterized protein. (514 aa)
MLF2Myeloid leukemia factor 2. (248 aa)
SELENOFSelenoprotein F. (164 aa)
P4HTMProlyl 4-hydroxylase, transmembrane. (529 aa)
DNAJC5GDnaJ heat shock protein family (Hsp40) member C5 gamma. (189 aa)
DNAJB4DnaJ heat shock protein family (Hsp40) member B4. (344 aa)
LOC100977183Uncharacterized protein. (448 aa)
P4HBProtein disulfide-isomerase. (513 aa)
SDF2L1Stromal cell derived factor 2 like 1. (221 aa)
PRKCSHProtein kinase C substrate 80K-H. (534 aa)
PPP5D1PPP5 tetratricopeptide repeat domain containing 1. (171 aa)
ERO1AEndoplasmic reticulum oxidoreductase 1 alpha. (468 aa)
EDEM2alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (578 aa)
ENSPPAP00000025633Uncharacterized protein. (58 aa)
DNAJA4DnaJ heat shock protein family (Hsp40) member A4. (426 aa)
ENSPPAP00000025878Uncharacterized protein; Belongs to the GroES chaperonin family. (110 aa)
DNAJB12DnaJ heat shock protein family (Hsp40) member B12. (409 aa)
SECISBP2LSECIS binding protein 2 like. (1101 aa)
UGGT2UDP-glucose glycoprotein glucosyltransferase 2. (1516 aa)
HSF4Heat shock transcription factor 4. (492 aa)
CD164CD164 molecule. (197 aa)
LOC100987269TPR_REGION domain-containing protein. (355 aa)
RABL3RAB, member of RAS oncogene family like 3. (255 aa)
HSPA2Heat shock protein family A (Hsp70) member 2; Belongs to the heat shock protein 70 family. (602 aa)
LOC100981595Uncharacterized protein. (400 aa)
ENSPPAP00000028140Uncharacterized protein; Belongs to the heat shock protein 70 family. (501 aa)
ERN2Endoplasmic reticulum to nucleus signaling 2. (926 aa)
DNAJB6DnaJ heat shock protein family (Hsp40) member B6. (326 aa)
LDLRAD1Low density lipoprotein receptor class A domain containing 1. (205 aa)
EDEM3alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (932 aa)
AGR2Anterior gradient 2, protein disulphide isomerase family member. (189 aa)
HIKESHIHeat shock protein nuclear import factor hikeshi. (197 aa)
STK40Serine/threonine kinase 40. (435 aa)
LONP1Lon protease homolog, mitochondrial; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial promoters and RNA in a single-stranded, site-specific, and strand- specific manner. May regulate mi [...] (943 aa)
HERPUD1Homocysteine inducible ER protein with ubiquitin like domain 1. (391 aa)
SIL1SIL1 nucleotide exchange factor. (463 aa)
ENSPPAP00000030902Uncharacterized protein. (149 aa)
ERP27Endoplasmic reticulum protein 27. (273 aa)
PPP5CSerine/threonine-protein phosphatase. (503 aa)
CDC37L1Cell division cycle 37 like 1. (337 aa)
ENSPPAP00000031383Uncharacterized protein. (354 aa)
TXNDC5Uncharacterized protein; Belongs to the protein disulfide isomerase family. (361 aa)
ENSPPAP00000031464Thioredoxin domain-containing protein. (484 aa)
EIF2AK1Eukaryotic translation initiation factor 2 alpha kinase 1. (630 aa)
TMX1Thioredoxin related transmembrane protein 1. (280 aa)
EIF2AK3Eukaryotic translation initiation factor 2 alpha kinase 3. (1115 aa)
ENSPPAP00000031897Aha1_N domain-containing protein. (122 aa)
SDF2Stromal cell derived factor 2. (211 aa)
HSPD1Heat shock protein family D (Hsp60) member 1; Belongs to the chaperonin (HSP60) family. (598 aa)
HSPBP1HSPA (Hsp70) binding protein 1. (323 aa)
HSP90B1Heat shock protein 90 beta family member 1. (814 aa)
PRDX4Peroxiredoxin 4. (271 aa)
HSP90AA1HATPase_c domain-containing protein. (854 aa)
NR3C1Nuclear receptor subfamily 3 group C member 1. (777 aa)
UGGT1UDP-glucose glycoprotein glucosyltransferase 1. (1557 aa)
ATF4Activating transcription factor 4. (340 aa)
ENSPPAP00000033303HATPase_c domain-containing protein. (320 aa)
BAG2BCL2 associated athanogene 2. (211 aa)
APOL6Apolipoprotein L6. (343 aa)
CALR3Calreticulin 3. (352 aa)
ENSPPAP00000033816HATPase_c domain-containing protein. (279 aa)
ENSPPAP00000034420Uncharacterized protein. (144 aa)
ENSPPAP00000034525Uncharacterized protein; Belongs to the heat shock protein 70 family. (584 aa)
TTC28Tetratricopeptide repeat domain 28. (2396 aa)
FKBP5Peptidylprolyl isomerase. (457 aa)
ENSPPAP00000034683Uncharacterized protein. (59 aa)
CLGNCalmegin. (610 aa)
DNAJC10DnaJ homolog subfamily C member 10; Endoplasmic reticulum disulfide reductase involved both in the correct folding of proteins and degradation of misfolded proteins. (793 aa)
CLPXCaseinolytic mitochondrial matrix peptidase chaperone subunit. (633 aa)
DNAJC25DnaJ heat shock protein family (Hsp40) member C25. (360 aa)
ENSPPAP00000036018Uncharacterized protein. (240 aa)
ENSPPAP00000036022Uncharacterized protein. (96 aa)
CLPPATP-dependent Clp protease proteolytic subunit. (277 aa)
HSPA8Uncharacterized protein; Belongs to the heat shock protein 70 family. (646 aa)
ENSPPAP00000036589Peptidylprolyl isomerase. (439 aa)
DNAJC9DnaJ heat shock protein family (Hsp40) member C9. (260 aa)
DNAJB5DnaJ heat shock protein family (Hsp40) member B5. (382 aa)
LOC100992102CS domain-containing protein. (137 aa)
EIF2S1Eukaryotic translation initiation factor 2 subunit alpha. (315 aa)
CDC37Cell division cycle 37. (378 aa)
HSPA4Heat shock protein family A (Hsp70) member 4. (840 aa)
ERP29Endoplasmic reticulum resident protein 29; Does not seem to be a disulfide isomerase. (261 aa)
SCCPDHSaccharopine dehydrogenase (putative). (370 aa)
DNAJB11J domain-containing protein. (358 aa)
SUGT1SGT1 homolog, MIS12 kinetochore complex assembly cochaperone. (364 aa)
STIP1Stress induced phosphoprotein 1. (590 aa)
DNAJC5BDnaJ heat shock protein family (Hsp40) member C5 beta. (199 aa)
BAG3BCL2 associated athanogene 3. (521 aa)
HSPA5Heat shock protein family A (Hsp70) member 5; Belongs to the heat shock protein 70 family. (654 aa)
USP33Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (942 aa)
GANABGlucosidase II alpha subunit; Belongs to the glycosyl hydrolase 31 family. (967 aa)
LOC100975678Uncharacterized protein; Belongs to the chaperonin (HSP60) family. (566 aa)
ENSPPAP00000041535J domain-containing protein. (478 aa)
TOMM34Translocase of outer mitochondrial membrane 34. (309 aa)
ERO1BEndoplasmic reticulum oxidoreductase 1 beta. (441 aa)
HSPA9Heat shock protein family A (Hsp70) member 9; Belongs to the heat shock protein 70 family. (679 aa)
ENSPPAP00000042396CHORD domain-containing protein. (134 aa)
EIF2AEukaryotic translation initiation factor 2A; Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl- tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner. (591 aa)
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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