5 items (Pan paniscus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CCNC	Cyclin C; Belongs to the cyclin family. (283 aa)
	MED12	Mediator complex subunit 12. (2182 aa)
	MED13	Mediator of RNA polymerase II transcription subunit 13; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (2173 aa)
	CDK8	Cyclin dependent kinase 8; Belongs to the protein kinase superfamily. (464 aa)
	CDK19	Cyclin dependent kinase 19. (502 aa)

Your Current Organism:

Pan paniscus

NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CCNC	CDK19	ENSPPAP00000011180	ENSPPAP00000027233	Cyclin C; Belongs to the cyclin family.	Cyclin dependent kinase 19.	0.996
CCNC	CDK8	ENSPPAP00000011180	ENSPPAP00000023961	Cyclin C; Belongs to the cyclin family.	Cyclin dependent kinase 8; Belongs to the protein kinase superfamily.	0.999
CCNC	MED12	ENSPPAP00000011180	ENSPPAP00000019175	Cyclin C; Belongs to the cyclin family.	Mediator complex subunit 12.	0.999
CCNC	MED13	ENSPPAP00000011180	ENSPPAP00000020649	Cyclin C; Belongs to the cyclin family.	Mediator of RNA polymerase II transcription subunit 13; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.997
CDK19	CCNC	ENSPPAP00000027233	ENSPPAP00000011180	Cyclin dependent kinase 19.	Cyclin C; Belongs to the cyclin family.	0.996
CDK19	CDK8	ENSPPAP00000027233	ENSPPAP00000023961	Cyclin dependent kinase 19.	Cyclin dependent kinase 8; Belongs to the protein kinase superfamily.	0.989
CDK19	MED12	ENSPPAP00000027233	ENSPPAP00000019175	Cyclin dependent kinase 19.	Mediator complex subunit 12.	0.999
CDK19	MED13	ENSPPAP00000027233	ENSPPAP00000020649	Cyclin dependent kinase 19.	Mediator of RNA polymerase II transcription subunit 13; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.994
CDK8	CCNC	ENSPPAP00000023961	ENSPPAP00000011180	Cyclin dependent kinase 8; Belongs to the protein kinase superfamily.	Cyclin C; Belongs to the cyclin family.	0.999
CDK8	CDK19	ENSPPAP00000023961	ENSPPAP00000027233	Cyclin dependent kinase 8; Belongs to the protein kinase superfamily.	Cyclin dependent kinase 19.	0.989
CDK8	MED12	ENSPPAP00000023961	ENSPPAP00000019175	Cyclin dependent kinase 8; Belongs to the protein kinase superfamily.	Mediator complex subunit 12.	0.998
CDK8	MED13	ENSPPAP00000023961	ENSPPAP00000020649	Cyclin dependent kinase 8; Belongs to the protein kinase superfamily.	Mediator of RNA polymerase II transcription subunit 13; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.998
MED12	CCNC	ENSPPAP00000019175	ENSPPAP00000011180	Mediator complex subunit 12.	Cyclin C; Belongs to the cyclin family.	0.999
MED12	CDK19	ENSPPAP00000019175	ENSPPAP00000027233	Mediator complex subunit 12.	Cyclin dependent kinase 19.	0.999
MED12	CDK8	ENSPPAP00000019175	ENSPPAP00000023961	Mediator complex subunit 12.	Cyclin dependent kinase 8; Belongs to the protein kinase superfamily.	0.998
MED12	MED13	ENSPPAP00000019175	ENSPPAP00000020649	Mediator complex subunit 12.	Mediator of RNA polymerase II transcription subunit 13; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.999
MED13	CCNC	ENSPPAP00000020649	ENSPPAP00000011180	Mediator of RNA polymerase II transcription subunit 13; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Cyclin C; Belongs to the cyclin family.	0.997
MED13	CDK19	ENSPPAP00000020649	ENSPPAP00000027233	Mediator of RNA polymerase II transcription subunit 13; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Cyclin dependent kinase 19.	0.994
MED13	CDK8	ENSPPAP00000020649	ENSPPAP00000023961	Mediator of RNA polymerase II transcription subunit 13; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Cyclin dependent kinase 8; Belongs to the protein kinase superfamily.	0.998
MED13	MED12	ENSPPAP00000020649	ENSPPAP00000019175	Mediator of RNA polymerase II transcription subunit 13; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Mediator complex subunit 12.	0.999