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| | AJUBA | Ajuba LIM protein. (538 aa) |
| | DCP1B | Decapping mRNA 1B. (621 aa) |
| | APOBEC3G | Uncharacterized protein. (101 aa) |
| | AGO4 | Protein argonaute-4; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. (860 aa) |
| | DCPS | Decapping enzyme, scavenger. (337 aa) |
| | AGO3 | Protein argonaute-3; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. (860 aa) |
| | DIS3L2 | DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase, such as ZCCHC11/TUT4. Mediates degradation of cytoplasmic mRNAs that have been deadenylated and subsequently uridylated at their 3'. Mediates degradation of uridylated pre-let-7 miRNAs, contributing to the maintenance of embryonic stem (ES) cells. Essential for correct mi [...] (889 aa) |
| | NANOS3 | Nanos C2HC-type zinc finger 3; Belongs to the nanos family. (192 aa) |
| | ZFP36 | ZFP36 ring finger protein. (332 aa) |
| | LSM1 | U6 snRNA-associated Sm-like protein LSm1; Plays a role in the degradation of histone mRNAs, the only eukaryotic mRNAs that are not polyadenylated. Probably also part of an LSm subunits-containing complex involved in the general process of mRNA degradation. (133 aa) |
| | LSM2 | U6 snRNA-associated Sm-like protein LSm2; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (95 aa) |
| | YTHDF2 | YTH N6-methyladenosine RNA binding protein 2. (595 aa) |
| | EDC4 | Enhancer of mRNA decapping 4. (1401 aa) |
| | RBPMS | RNA binding protein, mRNA processing factor. (197 aa) |
| | APOBEC3G-2 | DNA dC->dU-editing enzyme APOBEC-3G; DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility via deaminase- dependent and -independent mechanisms. After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription, it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA, leading to G-to-A hypermutations in the subsequent plus-strand viral DNA. The resultant detrimental levels of mutations in the proviral genome, along with a deamin [...] (413 aa) |
| | ENSPPAP00000020924 | Uncharacterized protein. (353 aa) |
| | IGF2BP3 | Insulin like growth factor 2 mRNA binding protein 3. (579 aa) |
| | BTBD2 | BTB domain-containing protein. (377 aa) |
| | LSM3 | U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (102 aa) |
| | PATL1 | PAT1 homolog 1, processing body mRNA decay factor. (770 aa) |
| | SQSTM1 | Sequestosome 1. (440 aa) |
| | ENSPPAP00000022320 | Uncharacterized protein. (203 aa) |
| | BTBD1 | BTB domain containing 1. (463 aa) |
| | IGF2BP2 | Insulin like growth factor 2 mRNA binding protein 2. (545 aa) |
| | EIF4E2 | Eukaryotic translation initiation factor 4E family member 2; Belongs to the eukaryotic initiation factor 4E family. (249 aa) |
| | DDX6 | DEAD-box helicase 6; Belongs to the DEAD box helicase family. (483 aa) |
| | AGO1 | Argonaute RISC component 1; Belongs to the argonaute family. (857 aa) |
| | ENSPPAP00000023984 | RRM domain-containing protein. (528 aa) |
| | ELAVL1 | ELAV-like protein; Belongs to the RRM elav family. (326 aa) |
| | RC3H2 | Ring finger and CCCH-type domains 2. (1191 aa) |
| | PSMA2 | Proteasome subunit alpha type. (234 aa) |
| | ENSPPAP00000026714 | Uncharacterized protein. (96 aa) |
| | ENSPPAP00000026880 | Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family. (222 aa) |
| | APOBEC3H | Apolipoprotein B mRNA editing enzyme catalytic subunit 3H. (200 aa) |
| | ENSPPAP00000027713 | ATPase_AAA_core domain-containing protein. (381 aa) |
| | EIF4ENIF1 | Eukaryotic translation initiation factor 4E nuclear import factor 1. (985 aa) |
| | CNOT7 | CCR4-NOT transcription complex subunit 7. (285 aa) |
| | CNOT9 | CCR4-NOT transcription complex subunit 9. (331 aa) |
| | SHFL | Shiftless antiviral inhibitor of ribosomal frameshifting. (291 aa) |
| | AGO2 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] (873 aa) |
| | LIN28A | Lin-28 homolog A. (209 aa) |
| | LSM6 | LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated. (80 aa) |
| | ENSPPAP00000030023 | RRM domain-containing protein. (486 aa) |
| | AICDA | Activation induced cytidine deaminase. (199 aa) |
| | ENSPPAP00000031085 | Uncharacterized protein. (277 aa) |
| | ENSPPAP00000031956 | HCLS1-associated protein X-1; Recruits the Arp2/3 complex to the cell cortex and regulates reorganization of the cortical actin cytoskeleton via its interaction with KCNC3 and the Arp2/3 complex. Slows down the rate of inactivation of KCNC3 channels. Promotes GNA13-mediated cell migration. Involved in the clathrin-mediated endocytosis pathway. May be involved in internalization of ABC transporters such as ABCB11. May inhibit CASP9 and CASP3. Promotes cell survival. May regulate intracellular calcium pools. (254 aa) |
| | LOC100995121 | Uncharacterized protein. (542 aa) |
| | ENSPPAP00000032433 | Uncharacterized protein. (64 aa) |
| | RC3H1 | Ring finger and CCCH-type domains 1. (1134 aa) |
| | TRIM5 | Tripartite motif-containing protein 5; Capsid-specific restriction factor that prevents infection from non-host-adapted retroviruses. Blocks viral replication early in the life cycle, after viral entry but before reverse transcription. In addition to acting as a capsid-specific restriction factor, also acts as a pattern recognition receptor that activates innate immune signaling in response to the retroviral capsid lattice. Binding to the viral capsid triggers its E3 ubiquitin ligase activity, and in concert with the heterodimeric ubiquitin conjugating enzyme complex UBE2V1- UBE2N (als [...] (493 aa) |
| | POLR2G | RNA polymerase II subunit G. (172 aa) |
| | LOC100972230 | Uncharacterized protein. (458 aa) |
| | ENSPPAP00000034250 | Uncharacterized protein; Belongs to the DEAD box helicase family. (413 aa) |
| | EDC3 | Enhancer of mRNA decapping 3. (508 aa) |
| | SAMD4A | Sterile alpha motif domain containing 4A. (641 aa) |
| | IGF2BP1 | Insulin like growth factor 2 mRNA binding protein 1. (577 aa) |
| | ENSPPAP00000035130 | Uncharacterized protein. (433 aa) |
| | ENSPPAP00000036339 | Uncharacterized protein. (244 aa) |
| | ZC3H12A | Zinc finger CCCH-type containing 12A. (599 aa) |
| | ZC3H12D | Zinc finger CCCH-type containing 12D. (526 aa) |
| | ENSPPAP00000038150 | AAA_lid_3 domain-containing protein. (351 aa) |
| | DCP2 | Decapping mRNA 2. (417 aa) |
| | PSMC3 | Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (446 aa) |
| | SAMD4B | Sterile alpha motif domain containing 4B. (694 aa) |
| | CNOT2 | CCR4-NOT transcription complex subunit 2. (550 aa) |
| | LSM14A | Uncharacterized protein. (477 aa) |
| | NOCT | Nocturnin. (394 aa) |
| | DCP1A | Decapping mRNA 1A. (582 aa) |
| | TOP1 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (765 aa) |
| | TRIM21 | Tripartite motif containing 21. (475 aa) |
| | YTHDF3 | YTH N6-methyladenosine RNA binding protein 3. (587 aa) |
| | EIF4E | Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family. (246 aa) |
| | CNOT8 | CCR4-NOT transcription complex subunit 8. (292 aa) |
| | UPF1 | UPF1 RNA helicase and ATPase. (1096 aa) |
| | ENSPPAP00000042775 | Sm domain-containing protein. (81 aa) |
| | PUM1 | Pumilio RNA binding family member 1. (1216 aa) |
| | LSM4 | U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (238 aa) |
| | POLR2D | RPOL4c domain-containing protein. (110 aa) |
| | C19orf54 | Chromosome 19 open reading frame 54. (351 aa) |
| | MOV10 | Mov10 RISC complex RNA helicase. (1005 aa) |
| | ENSPPAP00000015107 | Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family. (212 aa) |
| | ENSPPAP00000012261 | Uncharacterized protein. (663 aa) |
| | CARHSP1 | Calcium regulated heat stable protein 1. (147 aa) |
| | HAX1 | HCLS1-associated protein X-1; Recruits the Arp2/3 complex to the cell cortex and regulates reorganization of the cortical actin cytoskeleton via its interaction with KCNC3 and the Arp2/3 complex. Slows down the rate of inactivation of KCNC3 channels. Promotes GNA13-mediated cell migration. Involved in the clathrin-mediated endocytosis pathway. May be involved in internalization of ABC transporters such as ABCB11. May inhibit CASP9 and CASP3. Promotes cell survival. May regulate intracellular calcium pools. (279 aa) |
| | TNRC6B | Trinucleotide repeat containing adaptor 6B. (1833 aa) |
| | C9orf72 | C9orf72-SMCR8 complex subunit. (478 aa) |
| | TNRC6A | Trinucleotide repeat containing adaptor 6A. (1965 aa) |
| | TRIM71 | Tripartite motif containing 71. (744 aa) |
| | ENSPPAP00000009967 | Uncharacterized protein. (321 aa) |
| | ENSPPAP00000009956 | Uncharacterized protein. (245 aa) |
| | SYNE1 | Spectrin repeat containing nuclear envelope protein 1. (8797 aa) |
| | PAN3 | PAN2-PAN3 deadenylation complex subunit PAN3; Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA deca [...] (743 aa) |
| | PSMC2 | Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (432 aa) |
| | ZFP36L1 | ZFP36 ring finger protein like 1. (338 aa) |
| | ENSPPAP00000008310 | Uncharacterized protein. (212 aa) |
| | TNRC6C | Trinucleotide repeat containing adaptor 6C. (1928 aa) |
| | PSMA4 | Proteasome subunit alpha type. (261 aa) |
| | CSDE1 | Cold shock domain containing E1. (844 aa) |
| | PSMA6 | Proteasome subunit alpha type. (246 aa) |
| | LIMD1 | LIM domains containing 1. (676 aa) |
| | YTHDF1 | YTH N6-methyladenosine RNA binding protein 1. (584 aa) |
| | CNOT1 | CCR4-NOT transcription complex subunit 1. (2383 aa) |
| | NANOS2 | Nanos C2HC-type zinc finger 2; Belongs to the nanos family. (138 aa) |
| | MEX3B | Mex-3 RNA binding family member B. (595 aa) |
| | CAPRIN1 | Cell cycle associated protein 1. (721 aa) |
| | MEX3A | Mex-3 RNA binding family member A. (495 aa) |
| | APOBEC3C | Apolipoprotein B mRNA editing enzyme catalytic subunit 3C. (190 aa) |
| | ENSPPAP00000002927 | CCHC-type domain-containing protein. (202 aa) |
| | XRN1 | 5'-3' exoribonuclease 1. (1706 aa) |
| | APOBEC3B | Uncharacterized protein. (490 aa) |
| | CPEB1 | Cytoplasmic polyadenylation element binding protein 1. (626 aa) |
| | PATL2 | PAT1 homolog 2. (545 aa) |
| | KIAA0355 | KIAA0355. (1070 aa) |
| | CNOT3 | CCR4-NOT transcription complex subunit 3. (753 aa) |
| | NBDY | Negative regulator of P-body association. (68 aa) |
| | ENSPPAP00000000701 | RRM domain-containing protein. (528 aa) |
| | PAN2 | PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent [...] (1198 aa) |
