STRINGSTRING
HEY1 HEY1 PLK4 PLK4 PDGFB PDGFB ZNF568 ZNF568 PEG10 PEG10 EGLN1 EGLN1 FBXW8 FBXW8 WNT2 WNT2 ZFAT ZFAT CASP8 CASP8 KRT19 KRT19 PKD2 PKD2 TTPAL TTPAL NR2F2 NR2F2 OVOL2 OVOL2 NODAL NODAL BMP7 BMP7 HAND1 HAND1 CDX2 CDX2 VASH2 VASH2 ST14 ST14 HEY2 HEY2 EOMES EOMES ENSPPAP00000023291 ENSPPAP00000023291 FGFR2 FGFR2 E2F8 E2F8 TMED2 TMED2 IGF2 IGF2 CCN1 CCN1 BIRC6 BIRC6 EPAS1 EPAS1 WNT7B WNT7B ENSPPAP00000026779 ENSPPAP00000026779 HECTD1 HECTD1 TAF10 TAF10 CDX4 CDX4 PLCD3 PLCD3 BPTF BPTF DNAJB6 DNAJB6 CITED1 CITED1 MDFI MDFI VASH1 VASH1 TFEB TFEB SPINT1 SPINT1 SOX15 SOX15 TTPA TTPA NSDHL NSDHL GCM1 GCM1 AKT1 AKT1 MED1 MED1 ARNT ARNT STK3 STK3 SNAI1 SNAI1 CSF2 CSF2 RBPJ RBPJ NCOA1 NCOA1 GRHL2 GRHL2 LEF1 LEF1 CITED2 CITED2 PCDH12 PCDH12 EGFR EGFR RTL5 RTL5 PRDM1 PRDM1 JUNB JUNB MAPK1 MAPK1 HS6ST1 HS6ST1 GJB5 GJB5 SOCS3 SOCS3 CEBPA CEBPA RTL1 RTL1 LIF LIF GGNBP2 GGNBP2 RSPO3 RSPO3 IL10 IL10 BMP5 BMP5 E2F7 E2F7 ADM ADM HES1 HES1 TRIM28 TRIM28 FZD5 FZD5 SETD2 SETD2 ZFP36L1 ZFP36L1 STK4 STK4 GATA2 GATA2 GRB2 GRB2 ENSPPAP00000010058 ENSPPAP00000010058 SP3 SP3 HIF1A HIF1A ENSPPAP00000011807 ENSPPAP00000011807
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HEY1Hes related family bHLH transcription factor with YRPW motif 1. (304 aa)
PLK4Polo like kinase 4. (970 aa)
PDGFBPlatelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (241 aa)
ZNF568Uncharacterized protein. (657 aa)
PEG10CCHC-type domain-containing protein. (766 aa)
EGLN1Fe2OG dioxygenase domain-containing protein. (341 aa)
FBXW8F-box and WD repeat domain containing 8. (597 aa)
WNT2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa)
ZFATZinc finger and AT-hook domain containing. (1243 aa)
CASP8Caspase 8; Belongs to the peptidase C14A family. (496 aa)
KRT19Keratin 19; Belongs to the intermediate filament family. (400 aa)
PKD2Polycystin 2, transient receptor potential cation channel. (788 aa)
TTPALAlpha tocopherol transfer protein like. (342 aa)
NR2F2Uncharacterized protein. (333 aa)
OVOL2Ovo like zinc finger 2. (225 aa)
NODALNodal growth differentiation factor. (347 aa)
BMP7Bone morphogenetic protein 7. (431 aa)
HAND1Heart and neural crest derivatives expressed 1. (219 aa)
CDX2Caudal type homeobox 2. (313 aa)
VASH2Vasohibin 2. (290 aa)
ST14Suppressor of tumorigenicity 14 protein homolog; Degrades extracellular matrix. Belongs to the peptidase S1 family. (849 aa)
HEY2Hes related family bHLH transcription factor with YRPW motif 2. (337 aa)
EOMESEomesodermin. (680 aa)
ENSPPAP00000023291GOLD domain-containing protein; Belongs to the EMP24/GP25L family. (156 aa)
FGFR2Fibroblast growth factor receptor. (822 aa)
E2F8E2F transcription factor 8. (867 aa)
TMED2Transmembrane p24 trafficking protein 2. (208 aa)
IGF2Insulin like growth factor 2. (236 aa)
CCN1Cellular communication network factor 1. (381 aa)
BIRC6Baculoviral IAP repeat containing 6. (4915 aa)
EPAS1Endothelial PAS domain protein 1. (870 aa)
WNT7BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
ENSPPAP00000026779Uncharacterized protein. (720 aa)
HECTD1HECT domain E3 ubiquitin protein ligase 1. (2610 aa)
TAF10Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (186 aa)
CDX4Caudal type homeobox 4. (284 aa)
PLCD3Phosphoinositide phospholipase C. (737 aa)
BPTFBromodomain PHD finger transcription factor. (2855 aa)
DNAJB6DnaJ heat shock protein family (Hsp40) member B6. (326 aa)
CITED1Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1. (219 aa)
MDFIMyoD family inhibitor. (246 aa)
VASH1Vasohibin 1. (365 aa)
TFEBTranscription factor EB. (552 aa)
SPINT1Serine peptidase inhibitor, Kunitz type 1. (529 aa)
SOX15SRY-box transcription factor 15. (233 aa)
TTPAAlpha tocopherol transfer protein. (278 aa)
NSDHLNAD(P) dependent steroid dehydrogenase-like; Belongs to the 3-beta-HSD family. (373 aa)
GCM1Glial cells missing transcription factor 1. (436 aa)
AKT1Non-specific serine/threonine protein kinase. (501 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1555 aa)
ARNTAryl hydrocarbon receptor nuclear translocator. (789 aa)
STK3Serine/threonine kinase 3. (467 aa)
SNAI1Snail family transcriptional repressor 1. (264 aa)
CSF2Colony stimulating factor 2. (144 aa)
RBPJRecombination signal binding protein for immunoglobulin kappa J region. (499 aa)
NCOA1Nuclear receptor coactivator. (1441 aa)
GRHL2Grainyhead like transcription factor 2. (618 aa)
LEF1Lymphoid enhancer binding factor 1. (399 aa)
CITED2Uncharacterized protein. (179 aa)
PCDH12Protocadherin 12. (1184 aa)
EGFRReceptor protein-tyrosine kinase. (1201 aa)
RTL5Retrotrans_gag domain-containing protein. (402 aa)
PRDM1PR/SET domain 1. (825 aa)
JUNBJunB proto-oncogene, AP-1 transcription factor subunit. (347 aa)
MAPK1Mitogen-activated protein kinase. (339 aa)
HS6ST1Heparan-sulfate 6-O-sulfotransferase; 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate. (279 aa)
GJB5Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (273 aa)
SOCS3Suppressor of cytokine signaling 3. (225 aa)
CEBPABZIP domain-containing protein. (141 aa)
RTL1Retrotransposon Gag like 1. (1359 aa)
LIFLIF interleukin 6 family cytokine. (202 aa)
GGNBP2Gametogenetin binding protein 2. (699 aa)
RSPO3R-spondin 3. (291 aa)
IL10Interleukin 10. (178 aa)
BMP5Bone morphogenetic protein 5. (454 aa)
E2F7E2F transcription factor 7. (911 aa)
ADMAdrenomedullin. (185 aa)
HES1Hes family bHLH transcription factor 1. (280 aa)
TRIM28Tripartite motif containing 28. (736 aa)
FZD5Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. (585 aa)
SETD2SET domain containing 2, histone lysine methyltransferase. (2536 aa)
ZFP36L1ZFP36 ring finger protein like 1. (338 aa)
STK4Serine/threonine kinase 4. (487 aa)
GATA2GATA binding protein 2. (480 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
ENSPPAP00000010058Uncharacterized protein. (165 aa)
SP3Sp3 transcription factor. (721 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (850 aa)
ENSPPAP00000011807GOLD domain-containing protein. (200 aa)
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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