25 items (Pan paniscus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	FZD5	Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. (585 aa)
	AKR1B1	Aldo-keto reductase family 1 member B. (263 aa)
	CEBPA	BZIP domain-containing protein. (141 aa)
	ENSPPAP00000004989	Aldo_ket_red domain-containing protein. (269 aa)
	GATA2	GATA binding protein 2. (480 aa)
	HOXB13	Homeobox B13. (284 aa)
	TFCP2L1	Transcription factor CP2 like 1. (518 aa)
	PGR	Progesterone receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcriptional activator of several progesteron-dependent promoters in a variety of cell types. Involved in activation of SRC-dependent MAPK signaling on hormone stimulation. (636 aa)
	HIF1A	Hypoxia inducible factor 1 subunit alpha. (850 aa)
	SIX3	Homeobox domain-containing protein. (264 aa)
	GPAT4	Glycerol-3-phosphate acyltransferase 4. (456 aa)
	FEM1B	Fem-1 homolog B. (627 aa)
	TGFB1	Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
	ENSPPAP00000020108	PlsC domain-containing protein. (328 aa)
	ENSPPAP00000023190	Aldo_ket_red domain-containing protein. (294 aa)
	ENSPPAP00000024161	Aldo_ket_red domain-containing protein. (232 aa)
	HOXA5	Homeobox A5. (270 aa)
	KDR	Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa)
	TMEM79	Transmembrane protein 79. (394 aa)
	NKX6-1	Homeobox domain-containing protein. (310 aa)
	RFX3	Regulatory factor X3. (765 aa)
	BHLHA15	Basic helix-loop-helix family member a15. (171 aa)
	TYMS	Thymidylate synthetase. (313 aa)
	GDF11	Growth differentiation factor 11. (398 aa)
	EPAS1	Endothelial PAS domain protein 1. (870 aa)

Your Current Organism:

Pan paniscus

NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CEBPA	GATA2	ENSPPAP00000003416	ENSPPAP00000009054	BZIP domain-containing protein.	GATA binding protein 2.	0.771
CEBPA	HIF1A	ENSPPAP00000003416	ENSPPAP00000010904	BZIP domain-containing protein.	Hypoxia inducible factor 1 subunit alpha.	0.623
CEBPA	TGFB1	ENSPPAP00000003416	ENSPPAP00000017066	BZIP domain-containing protein.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.680
EPAS1	FEM1B	ENSPPAP00000026720	ENSPPAP00000014713	Endothelial PAS domain protein 1.	Fem-1 homolog B.	0.471
EPAS1	HIF1A	ENSPPAP00000026720	ENSPPAP00000010904	Endothelial PAS domain protein 1.	Hypoxia inducible factor 1 subunit alpha.	0.996
EPAS1	KDR	ENSPPAP00000026720	ENSPPAP00000040244	Endothelial PAS domain protein 1.	Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.510
FEM1B	EPAS1	ENSPPAP00000014713	ENSPPAP00000026720	Fem-1 homolog B.	Endothelial PAS domain protein 1.	0.471
FEM1B	HIF1A	ENSPPAP00000014713	ENSPPAP00000010904	Fem-1 homolog B.	Hypoxia inducible factor 1 subunit alpha.	0.449
FZD5	TFCP2L1	ENSPPAP00000000280	ENSPPAP00000009802	Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family.	Transcription factor CP2 like 1.	0.563
GATA2	CEBPA	ENSPPAP00000009054	ENSPPAP00000003416	GATA binding protein 2.	BZIP domain-containing protein.	0.771
GATA2	HIF1A	ENSPPAP00000009054	ENSPPAP00000010904	GATA binding protein 2.	Hypoxia inducible factor 1 subunit alpha.	0.480
GATA2	KDR	ENSPPAP00000009054	ENSPPAP00000040244	GATA binding protein 2.	Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.547
GATA2	PGR	ENSPPAP00000009054	ENSPPAP00000009925	GATA binding protein 2.	Progesterone receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcriptional activator of several progesteron-dependent promoters in a variety of cell types. Involved in activation of SRC-dependent MAPK signaling on hormone stimulation.	0.555
HIF1A	CEBPA	ENSPPAP00000010904	ENSPPAP00000003416	Hypoxia inducible factor 1 subunit alpha.	BZIP domain-containing protein.	0.623
HIF1A	EPAS1	ENSPPAP00000010904	ENSPPAP00000026720	Hypoxia inducible factor 1 subunit alpha.	Endothelial PAS domain protein 1.	0.996
HIF1A	FEM1B	ENSPPAP00000010904	ENSPPAP00000014713	Hypoxia inducible factor 1 subunit alpha.	Fem-1 homolog B.	0.449
HIF1A	GATA2	ENSPPAP00000010904	ENSPPAP00000009054	Hypoxia inducible factor 1 subunit alpha.	GATA binding protein 2.	0.480
HIF1A	KDR	ENSPPAP00000010904	ENSPPAP00000040244	Hypoxia inducible factor 1 subunit alpha.	Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.579
HIF1A	PGR	ENSPPAP00000010904	ENSPPAP00000009925	Hypoxia inducible factor 1 subunit alpha.	Progesterone receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcriptional activator of several progesteron-dependent promoters in a variety of cell types. Involved in activation of SRC-dependent MAPK signaling on hormone stimulation.	0.575
HIF1A	TGFB1	ENSPPAP00000010904	ENSPPAP00000017066	Hypoxia inducible factor 1 subunit alpha.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.609