(8 nodes) Atrioventricular node development network (Pan paniscus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	MAML1	Mastermind like transcriptional coactivator 1. (911 aa)
	GATA6	Uncharacterized protein. (402 aa)
	TBX5	T-box transcription factor 5. (518 aa)
	NOTCH2	Notch receptor 2. (2254 aa)
	NKX2-5	NK2 homeobox 5. (325 aa)
	GATA4	GATA binding protein 4. (396 aa)
	NOTCH1	Notch receptor 1. (2573 aa)
	BMPR1A	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)

Your Current Organism:

Pan paniscus

NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GATA4	GATA6	ENSPPAP00000000601	ENSPPAP00000003349	GATA binding protein 4.	Uncharacterized protein.	0.496
GATA4	NKX2-5	ENSPPAP00000000601	ENSPPAP00000015856	GATA binding protein 4.	NK2 homeobox 5.	0.997
GATA4	TBX5	ENSPPAP00000000601	ENSPPAP00000012540	GATA binding protein 4.	T-box transcription factor 5.	0.942
GATA6	GATA4	ENSPPAP00000003349	ENSPPAP00000000601	Uncharacterized protein.	GATA binding protein 4.	0.496
GATA6	NKX2-5	ENSPPAP00000003349	ENSPPAP00000015856	Uncharacterized protein.	NK2 homeobox 5.	0.817
GATA6	TBX5	ENSPPAP00000003349	ENSPPAP00000012540	Uncharacterized protein.	T-box transcription factor 5.	0.576
MAML1	NOTCH1	ENSPPAP00000001220	ENSPPAP00000033437	Mastermind like transcriptional coactivator 1.	Notch receptor 1.	0.999
MAML1	NOTCH2	ENSPPAP00000001220	ENSPPAP00000013961	Mastermind like transcriptional coactivator 1.	Notch receptor 2.	0.981
NKX2-5	GATA4	ENSPPAP00000015856	ENSPPAP00000000601	NK2 homeobox 5.	GATA binding protein 4.	0.997
NKX2-5	GATA6	ENSPPAP00000015856	ENSPPAP00000003349	NK2 homeobox 5.	Uncharacterized protein.	0.817
NKX2-5	TBX5	ENSPPAP00000015856	ENSPPAP00000012540	NK2 homeobox 5.	T-box transcription factor 5.	0.996
NOTCH1	MAML1	ENSPPAP00000033437	ENSPPAP00000001220	Notch receptor 1.	Mastermind like transcriptional coactivator 1.	0.999
NOTCH1	NOTCH2	ENSPPAP00000033437	ENSPPAP00000013961	Notch receptor 1.	Notch receptor 2.	0.947
NOTCH2	MAML1	ENSPPAP00000013961	ENSPPAP00000001220	Notch receptor 2.	Mastermind like transcriptional coactivator 1.	0.981
NOTCH2	NOTCH1	ENSPPAP00000013961	ENSPPAP00000033437	Notch receptor 2.	Notch receptor 1.	0.947
TBX5	GATA4	ENSPPAP00000012540	ENSPPAP00000000601	T-box transcription factor 5.	GATA binding protein 4.	0.942
TBX5	GATA6	ENSPPAP00000012540	ENSPPAP00000003349	T-box transcription factor 5.	Uncharacterized protein.	0.576
TBX5	NKX2-5	ENSPPAP00000012540	ENSPPAP00000015856	T-box transcription factor 5.	NK2 homeobox 5.	0.996