21 items (Pan paniscus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ROBO1	Roundabout guidance receptor 1. (1684 aa)
	BMP5	Bone morphogenetic protein 5. (454 aa)
	APLNR	Apelin receptor; Belongs to the G-protein coupled receptor 1 family. (380 aa)
	SNAI2	Snail family transcriptional repressor 2. (268 aa)
	SMAD4	Mothers against decapentaplegic homolog. (552 aa)
	TBX3	T-box transcription factor 3. (723 aa)
	HEYL	Hes related family bHLH transcription factor with YRPW motif like. (327 aa)
	BMP2	Bone morphogenetic protein 2. (396 aa)
	TBX2	T-box transcription factor 2. (622 aa)
	ENG	Endoglin. (658 aa)
	BMP7	Bone morphogenetic protein 7. (431 aa)
	MSX1	Msh homeobox 1. (249 aa)
	TBX20	Uncharacterized protein. (379 aa)
	HEY2	Hes related family bHLH transcription factor with YRPW motif 2. (337 aa)
	DCHS1	Dachsous cadherin-related 1. (3175 aa)
	NOTCH1	Notch receptor 1. (2573 aa)
	BMPR1A	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
	FGF8	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (210 aa)
	SNAI1	Snail family transcriptional repressor 1. (264 aa)
	RBPJ	Recombination signal binding protein for immunoglobulin kappa J region. (499 aa)
	ROBO2	Roundabout guidance receptor 2. (1439 aa)

Your Current Organism:

Pan paniscus

NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BMP2	BMP5	ENSPPAP00000014674	ENSPPAP00000001212	Bone morphogenetic protein 2.	Bone morphogenetic protein 5.	0.580
BMP2	BMP7	ENSPPAP00000014674	ENSPPAP00000018925	Bone morphogenetic protein 2.	Bone morphogenetic protein 7.	0.891
BMP2	BMPR1A	ENSPPAP00000014674	ENSPPAP00000033833	Bone morphogenetic protein 2.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.999
BMP2	ENG	ENSPPAP00000014674	ENSPPAP00000016080	Bone morphogenetic protein 2.	Endoglin.	0.653
BMP2	FGF8	ENSPPAP00000014674	ENSPPAP00000034277	Bone morphogenetic protein 2.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.668
BMP2	MSX1	ENSPPAP00000014674	ENSPPAP00000019486	Bone morphogenetic protein 2.	Msh homeobox 1.	0.560
BMP2	SMAD4	ENSPPAP00000014674	ENSPPAP00000009478	Bone morphogenetic protein 2.	Mothers against decapentaplegic homolog.	0.882
BMP2	TBX2	ENSPPAP00000014674	ENSPPAP00000015093	Bone morphogenetic protein 2.	T-box transcription factor 2.	0.406
BMP2	TBX3	ENSPPAP00000014674	ENSPPAP00000010916	Bone morphogenetic protein 2.	T-box transcription factor 3.	0.477
BMP5	BMP2	ENSPPAP00000001212	ENSPPAP00000014674	Bone morphogenetic protein 5.	Bone morphogenetic protein 2.	0.580
BMP5	BMPR1A	ENSPPAP00000001212	ENSPPAP00000033833	Bone morphogenetic protein 5.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.978
BMP5	FGF8	ENSPPAP00000001212	ENSPPAP00000034277	Bone morphogenetic protein 5.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.448
BMP5	MSX1	ENSPPAP00000001212	ENSPPAP00000019486	Bone morphogenetic protein 5.	Msh homeobox 1.	0.447
BMP5	SMAD4	ENSPPAP00000001212	ENSPPAP00000009478	Bone morphogenetic protein 5.	Mothers against decapentaplegic homolog.	0.409
BMP7	BMP2	ENSPPAP00000018925	ENSPPAP00000014674	Bone morphogenetic protein 7.	Bone morphogenetic protein 2.	0.891
BMP7	BMPR1A	ENSPPAP00000018925	ENSPPAP00000033833	Bone morphogenetic protein 7.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.992
BMP7	ENG	ENSPPAP00000018925	ENSPPAP00000016080	Bone morphogenetic protein 7.	Endoglin.	0.606
BMP7	FGF8	ENSPPAP00000018925	ENSPPAP00000034277	Bone morphogenetic protein 7.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.504
BMP7	MSX1	ENSPPAP00000018925	ENSPPAP00000019486	Bone morphogenetic protein 7.	Msh homeobox 1.	0.424
BMP7	SMAD4	ENSPPAP00000018925	ENSPPAP00000009478	Bone morphogenetic protein 7.	Mothers against decapentaplegic homolog.	0.697