(24 nodes) Positive regulation of cardiac muscle hypertrophy network (Pan paniscus)

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second shell of interactors

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proteins of unknown 3D structure

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Known Interactions

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Predicted Interactions

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Your Input:
	IGF1	IlGF domain-containing protein. (196 aa)
	MEF2A	Myocyte enhancer factor 2A. (505 aa)
	PDE9A	Phosphodiesterase. (593 aa)
	EDN1	Endothelin 1. (212 aa)
	CAMK2D	Calcium/calmodulin dependent protein kinase II delta. (533 aa)
	PRKCA	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (625 aa)
	TRPC3	Transient receptor potential cation channel subfamily C member 3; Belongs to the transient receptor (TC 1.A.4) family. (899 aa)
	PARP2	Poly [ADP-ribose] polymerase. (565 aa)
	CDK9	Cyclin dependent kinase 9; Belongs to the protein kinase superfamily. (372 aa)
	AKAP6	A-kinase anchoring protein 6. (2319 aa)
	BECN1	Beclin 1. (450 aa)
	ROCK2	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1384 aa)
	HAMP	Hepcidin antimicrobial peptide. (84 aa)
	ROCK1	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1368 aa)
	PDE5A	Phosphodiesterase. (875 aa)
	PARP1	Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1014 aa)
	MTPN	Myotrophin. (118 aa)
	BMP10	Bone morphogenetic protein 10. (424 aa)
	NR4A3	Nuclear receptor domain-containing protein. (359 aa)
	PPP3CA	Serine/threonine-protein phosphatase. (521 aa)
	TWF1	Twinfilin actin binding protein 1. (380 aa)
	ADRA1A	Adrenoceptor alpha 1A. (495 aa)
	SLC9A1	Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (815 aa)
	HAND2	Uncharacterized protein. (66 aa)

Your Current Organism:

Pan paniscus

NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADRA1A	EDN1	ENSPPAP00000042471	ENSPPAP00000013795	Adrenoceptor alpha 1A.	Endothelin 1.	0.488
AKAP6	MEF2A	ENSPPAP00000027194	ENSPPAP00000024118	A-kinase anchoring protein 6.	Myocyte enhancer factor 2A.	0.420
BECN1	PARP1	ENSPPAP00000030010	ENSPPAP00000036168	Beclin 1.	Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair.	0.490
BECN1	ROCK1	ENSPPAP00000030010	ENSPPAP00000034958	Beclin 1.	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.	0.454
BMP10	PARP1	ENSPPAP00000037922	ENSPPAP00000036168	Bone morphogenetic protein 10.	Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair.	0.523
EDN1	ADRA1A	ENSPPAP00000013795	ENSPPAP00000042471	Endothelin 1.	Adrenoceptor alpha 1A.	0.488
EDN1	HAND2	ENSPPAP00000013795	ENSPPAP00000002765	Endothelin 1.	Uncharacterized protein.	0.500
EDN1	IGF1	ENSPPAP00000013795	ENSPPAP00000003648	Endothelin 1.	IlGF domain-containing protein.	0.459
EDN1	PDE5A	ENSPPAP00000013795	ENSPPAP00000036907	Endothelin 1.	Phosphodiesterase.	0.478
HAND2	EDN1	ENSPPAP00000002765	ENSPPAP00000013795	Uncharacterized protein.	Endothelin 1.	0.500
HAND2	MEF2A	ENSPPAP00000002765	ENSPPAP00000024118	Uncharacterized protein.	Myocyte enhancer factor 2A.	0.614
IGF1	EDN1	ENSPPAP00000003648	ENSPPAP00000013795	IlGF domain-containing protein.	Endothelin 1.	0.459
MEF2A	AKAP6	ENSPPAP00000024118	ENSPPAP00000027194	Myocyte enhancer factor 2A.	A-kinase anchoring protein 6.	0.420
MEF2A	HAND2	ENSPPAP00000024118	ENSPPAP00000002765	Myocyte enhancer factor 2A.	Uncharacterized protein.	0.614
MEF2A	PPP3CA	ENSPPAP00000024118	ENSPPAP00000039955	Myocyte enhancer factor 2A.	Serine/threonine-protein phosphatase.	0.486
PARP1	BECN1	ENSPPAP00000036168	ENSPPAP00000030010	Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair.	Beclin 1.	0.490
PARP1	BMP10	ENSPPAP00000036168	ENSPPAP00000037922	Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair.	Bone morphogenetic protein 10.	0.523
PARP1	PARP2	ENSPPAP00000036168	ENSPPAP00000024124	Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair.	Poly [ADP-ribose] polymerase.	0.941
PARP2	PARP1	ENSPPAP00000024124	ENSPPAP00000036168	Poly [ADP-ribose] polymerase.	Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair.	0.941
PDE5A	EDN1	ENSPPAP00000036907	ENSPPAP00000013795	Phosphodiesterase.	Endothelin 1.	0.478