6 items (Pan paniscus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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Others

textmining

co-expression

protein homology

Your Input:
	RBBP8	RB binding protein 8, endonuclease. (895 aa)
	HELQ	Helicase, POLQ like. (1101 aa)
	SLX1A	Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. Has a preference for 5'-flap structures, and promotes symmetrical cleavage of static and migrating Holliday junctions (HJs). Resolves HJs by generating two pairs of ligatable, nicked duplex products. (275 aa)
	RAD52	RAD52 homolog, DNA repair protein. (417 aa)
	ENSPPAP00000021658	Uncharacterized protein. (339 aa)
	SLX4	SLX4 structure-specific endonuclease subunit. (1833 aa)

Your Current Organism:

Pan paniscus

NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPPAP00000021658	RBBP8	ENSPPAP00000021658	ENSPPAP00000006435	Uncharacterized protein.	RB binding protein 8, endonuclease.	0.709
ENSPPAP00000021658	SLX4	ENSPPAP00000021658	ENSPPAP00000041836	Uncharacterized protein.	SLX4 structure-specific endonuclease subunit.	0.429
HELQ	RBBP8	ENSPPAP00000001159	ENSPPAP00000006435	Helicase, POLQ like.	RB binding protein 8, endonuclease.	0.513
HELQ	SLX1A	ENSPPAP00000001159	ENSPPAP00000002270	Helicase, POLQ like.	Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. Has a preference for 5'-flap structures, and promotes symmetrical cleavage of static and migrating Holliday junctions (HJs). Resolves HJs by generating two pairs of ligatable, nicked duplex products.	0.443
HELQ	SLX4	ENSPPAP00000001159	ENSPPAP00000041836	Helicase, POLQ like.	SLX4 structure-specific endonuclease subunit.	0.401
RAD52	RBBP8	ENSPPAP00000003015	ENSPPAP00000006435	RAD52 homolog, DNA repair protein.	RB binding protein 8, endonuclease.	0.709
RAD52	SLX4	ENSPPAP00000003015	ENSPPAP00000041836	RAD52 homolog, DNA repair protein.	SLX4 structure-specific endonuclease subunit.	0.429
RBBP8	ENSPPAP00000021658	ENSPPAP00000006435	ENSPPAP00000021658	RB binding protein 8, endonuclease.	Uncharacterized protein.	0.709
RBBP8	HELQ	ENSPPAP00000006435	ENSPPAP00000001159	RB binding protein 8, endonuclease.	Helicase, POLQ like.	0.513
RBBP8	RAD52	ENSPPAP00000006435	ENSPPAP00000003015	RB binding protein 8, endonuclease.	RAD52 homolog, DNA repair protein.	0.709
RBBP8	SLX1A	ENSPPAP00000006435	ENSPPAP00000002270	RB binding protein 8, endonuclease.	Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. Has a preference for 5'-flap structures, and promotes symmetrical cleavage of static and migrating Holliday junctions (HJs). Resolves HJs by generating two pairs of ligatable, nicked duplex products.	0.619
RBBP8	SLX4	ENSPPAP00000006435	ENSPPAP00000041836	RB binding protein 8, endonuclease.	SLX4 structure-specific endonuclease subunit.	0.724
SLX1A	HELQ	ENSPPAP00000002270	ENSPPAP00000001159	Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. Has a preference for 5'-flap structures, and promotes symmetrical cleavage of static and migrating Holliday junctions (HJs). Resolves HJs by generating two pairs of ligatable, nicked duplex products.	Helicase, POLQ like.	0.443
SLX1A	RBBP8	ENSPPAP00000002270	ENSPPAP00000006435	Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. Has a preference for 5'-flap structures, and promotes symmetrical cleavage of static and migrating Holliday junctions (HJs). Resolves HJs by generating two pairs of ligatable, nicked duplex products.	RB binding protein 8, endonuclease.	0.619
SLX1A	SLX4	ENSPPAP00000002270	ENSPPAP00000041836	Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. Has a preference for 5'-flap structures, and promotes symmetrical cleavage of static and migrating Holliday junctions (HJs). Resolves HJs by generating two pairs of ligatable, nicked duplex products.	SLX4 structure-specific endonuclease subunit.	0.994
SLX4	ENSPPAP00000021658	ENSPPAP00000041836	ENSPPAP00000021658	SLX4 structure-specific endonuclease subunit.	Uncharacterized protein.	0.429
SLX4	HELQ	ENSPPAP00000041836	ENSPPAP00000001159	SLX4 structure-specific endonuclease subunit.	Helicase, POLQ like.	0.401
SLX4	RAD52	ENSPPAP00000041836	ENSPPAP00000003015	SLX4 structure-specific endonuclease subunit.	RAD52 homolog, DNA repair protein.	0.429
SLX4	RBBP8	ENSPPAP00000041836	ENSPPAP00000006435	SLX4 structure-specific endonuclease subunit.	RB binding protein 8, endonuclease.	0.724
SLX4	SLX1A	ENSPPAP00000041836	ENSPPAP00000002270	SLX4 structure-specific endonuclease subunit.	Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. Has a preference for 5'-flap structures, and promotes symmetrical cleavage of static and migrating Holliday junctions (HJs). Resolves HJs by generating two pairs of ligatable, nicked duplex products.	0.994