STRINGSTRING
FUT1 FUT1 NRP1 NRP1 TRIOBP TRIOBP LOC100972059 LOC100972059 RSU1 RSU1 CASS4 CASS4 MYADM MYADM UTRN UTRN CD36 CD36 DNM2 DNM2 CALR CALR WNT4 WNT4 RELL2 RELL2 CCL21 CCL21 FBLN2 FBLN2 FLNA FLNA CRKL CRKL UNC13D UNC13D FERMT1 FERMT1 JAK2 JAK2 NDNF NDNF MDK MDK EMP2 EMP2 ARHGEF7 ARHGEF7 SDC4 SDC4 APOA1 APOA1 VEGFA VEGFA PREX1 PREX1 CCDC80 CCDC80 STK4 STK4 EMILIN1 EMILIN1 HRG HRG PTPRJ PTPRJ EFEMP2 EFEMP2 NEDD9 NEDD9 DAB2 DAB2 ALOX15 ALOX15 LRRC45 LRRC45 EGFL6 EGFL6 TSTA3 TSTA3 PDGFB PDGFB ILK ILK CRK CRK COL26A1 COL26A1 C1QBP C1QBP THY1 THY1 ITGB3 ITGB3 ENSPPAP00000014694 ENSPPAP00000014694 HAS2 HAS2 CDC42 CDC42 CCL25 CCL25 EMID1 EMID1 DISC1 DISC1 CD3E CD3E FBLN1 FBLN1 LOC100993131 LOC100993131 FGB FGB HACD1 HACD1 RAC1 RAC1 POLDIP2 POLDIP2 PRKCE PRKCE ABI3BP ABI3BP FGA FGA PPM1F PPM1F VWC2 VWC2 CIB1 CIB1 KDR KDR CSF1 CSF1 PRKCZ PRKCZ CCL28 CCL28 DMD DMD ENSPPAP00000039413 ENSPPAP00000039413 CCR7 CCR7 MYOC MYOC CSPG5 CSPG5 ARL2 ARL2 DMTN DMTN FN1 FN1 FGG FGG ITGA5 ITGA5 HSD17B12 HSD17B12 DOCK5 DOCK5 GSK3B GSK3B JUP JUP DMP1 DMP1 DOCK1 DOCK1 ENSPPAP00000035019 ENSPPAP00000035019 ROCK1 ROCK1 FMN1 FMN1 COL8A1 COL8A1 CDH13 CDH13 ITGB1BP1 ITGB1BP1 TESK1 TESK1 SKAP1 SKAP1 CARMIL1 CARMIL1 PLEKHA2 PLEKHA2 PTK2B PTK2B MAP4K4 MAP4K4 HPSE HPSE S100A10 S100A10 SPOCK2 SPOCK2 AGR2 AGR2 RIN2 RIN2 LIMS2 LIMS2 EPB41L5 EPB41L5 RREB1 RREB1 ENSPPAP00000026998 ENSPPAP00000026998 CX3CL1 CX3CL1 LIMS1 LIMS1 ABL1 ABL1 ARPC2 ARPC2 NINJ1 NINJ1 OLFM4 OLFM4 CCN1 CCN1 BRAF BRAF ENSPPAP00000025597 ENSPPAP00000025597 DAG1 DAG1 FOXF1 FOXF1 P4HB P4HB VIT VIT TSC1 TSC1 CEACAM6 CEACAM6 ENSPPAP00000023887 ENSPPAP00000023887 EDIL3 EDIL3 CDK6 CDK6 EGFLAM EGFLAM NPNT NPNT SFRP1 SFRP1 TEK TEK EPHA1 EPHA1 NID1 NID1 FERMT2 FERMT2 ITGA3 ITGA3 SMAD3 SMAD3 ECM2 ECM2 RRAS RRAS LOC100989777 LOC100989777
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FUT1L-Fucosyltransferase; Belongs to the glycosyltransferase 11 family. (366 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (924 aa)
TRIOBPTRIO and F-actin binding protein. (2074 aa)
LOC100972059MARVEL domain-containing protein. (154 aa)
RSU1Ras suppressor protein 1. (277 aa)
CASS4Cas scaffold protein family member 4. (812 aa)
MYADMMyeloid associated differentiation marker. (322 aa)
UTRNUtrophin. (3433 aa)
CD36CD36 molecule; Belongs to the CD36 family. (472 aa)
DNM2Dynamin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (785 aa)
CALRCalreticulin. (417 aa)
WNT4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (342 aa)
RELL2RELT like 2. (310 aa)
CCL21C-C motif chemokine ligand 21. (134 aa)
FBLN2Fibulin 2. (1231 aa)
FLNAUncharacterized protein. (2188 aa)
CRKLCRK like proto-oncogene, adaptor protein. (303 aa)
UNC13DUnc-13 homolog D. (1079 aa)
FERMT1Fermitin family member 1. (677 aa)
JAK2Tyrosine-protein kinase. (1143 aa)
NDNFNeuron derived neurotrophic factor. (568 aa)
MDKMidkine. (143 aa)
EMP2Epithelial membrane protein 2; Functions as a key regulator of cell membrane composition by regulating proteins surface expression. Also, plays a role in regulation of processes including cell migration, cell proliferation, cell contraction and cell adhesion; Belongs to the PMP-22/EMP/MP20 family. (167 aa)
ARHGEF7Rho guanine nucleotide exchange factor 7. (780 aa)
SDC4Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (199 aa)
APOA1Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility (By similarity); Belongs to the apolipoprotein A1/A4/E family. (267 aa)
VEGFAVascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (372 aa)
PREX1Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1. (1645 aa)
CCDC80Coiled-coil domain containing 80. (949 aa)
STK4Serine/threonine kinase 4. (487 aa)
EMILIN1Elastin microfibril interfacer 1. (1016 aa)
HRGHistidine rich glycoprotein. (525 aa)
PTPRJProtein tyrosine phosphatase receptor type J. (1313 aa)
EFEMP2EGF containing fibulin extracellular matrix protein 2. (443 aa)
NEDD9Neural precursor cell expressed, developmentally down-regulated 9. (839 aa)
DAB2DAB adaptor protein 2. (752 aa)
ALOX15Arachidonate 15-lipoxygenase. (662 aa)
LRRC45Leucine rich repeat containing 45. (670 aa)
EGFL6EGF like domain multiple 6. (553 aa)
TSTA3Tissue specific transplantation antigen P35B. (321 aa)
PDGFBPlatelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (241 aa)
ILKIntegrin linked kinase. (533 aa)
CRKCRK proto-oncogene, adaptor protein. (304 aa)
COL26A1Collagen type XXVI alpha 1 chain. (388 aa)
C1QBPComplement C1q binding protein. (282 aa)
THY1Thy-1 cell surface antigen. (161 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (814 aa)
ENSPPAP00000014694Uncharacterized protein. (107 aa)
HAS2Hyaluronan synthase 2. (552 aa)
CDC42Uncharacterized protein. (191 aa)
CCL25C-C motif chemokine ligand 25. (150 aa)
EMID1EMI domain containing 1. (437 aa)
DISC1DISC1 scaffold protein. (835 aa)
CD3ECD3e molecule. (207 aa)
FBLN1Fibulin-1; Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes. (720 aa)
LOC100993131Cell division control protein 42 homolog. (191 aa)
FGBFibrinogen beta chain. (491 aa)
HACD1Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (274 aa)
RAC1Uncharacterized protein. (224 aa)
POLDIP2DNA polymerase delta interacting protein 2. (368 aa)
PRKCEProtein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (737 aa)
ABI3BPUncharacterized protein. (1571 aa)
FGAFib_alpha domain-containing protein. (288 aa)
PPM1FProtein phosphatase, Mg2+/Mn2+ dependent 1F. (454 aa)
VWC2Von Willebrand factor C domain containing 2. (325 aa)
CIB1Uncharacterized protein. (143 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa)
CSF1Macrophage colony-stimulating factor 1; Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female [...] (549 aa)
PRKCZProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (522 aa)
CCL28C-C motif chemokine. (127 aa)
DMDDystrophin. (3517 aa)
ENSPPAP00000039413Uncharacterized protein. (181 aa)
CCR7C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family. (372 aa)
MYOCMyocilin. (504 aa)
CSPG5Chondroitin sulfate proteoglycan 5. (562 aa)
ARL2ADP ribosylation factor like GTPase 2; Belongs to the small GTPase superfamily. Arf family. (184 aa)
DMTNDematin actin binding protein. (405 aa)
FN1Fibronectin 1. (2477 aa)
FGGFibrinogen gamma chain. (461 aa)
ITGA5Integrin subunit alpha 5; Belongs to the integrin alpha chain family. (1046 aa)
HSD17B12Hydroxysteroid 17-beta dehydrogenase 12; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (312 aa)
DOCK5Dedicator of cytokinesis 5; Belongs to the DOCK family. (1870 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (481 aa)
JUPJunction plakoglobin. (745 aa)
DMP1Dentin matrix acidic phosphoprotein 1. (513 aa)
DOCK1Dedicator of cytokinesis 1; Belongs to the DOCK family. (1870 aa)
ENSPPAP00000035019Uncharacterized protein. (111 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1368 aa)
FMN1Formin 1. (1420 aa)
COL8A1Collagen type VIII alpha 1 chain. (745 aa)
CDH13Cadherin 13. (698 aa)
ITGB1BP1Integrin subunit beta 1 binding protein 1. (200 aa)
TESK1Testis associated actin remodelling kinase 1. (625 aa)
SKAP1Src kinase associated phosphoprotein 1. (359 aa)
CARMIL1Capping protein regulator and myosin 1 linker 1. (1425 aa)
PLEKHA2Pleckstrin homology domain containing A2. (425 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa)
MAP4K4Mitogen-activated protein kinase kinase kinase kinase 4. (1348 aa)
HPSEHeparanase. (543 aa)
S100A10S100 calcium binding protein A10; Belongs to the S-100 family. (97 aa)
SPOCK2SPARC (osteonectin), cwcv and kazal like domains proteoglycan 2. (421 aa)
AGR2Anterior gradient 2, protein disulphide isomerase family member. (189 aa)
RIN2Ras and Rab interactor 2. (943 aa)
LIMS2LIM and senescent cell antigen-like-containing domain protein; Adapter protein in a cytoplasmic complex linking beta- integrins to the actin cytoskeleton, bridges the complex to cell surface receptor tyrosine kinases and growth factor receptors. (365 aa)
EPB41L5Erythrocyte membrane protein band 4.1 like 5. (733 aa)
RREB1Ras responsive element binding protein 1. (1742 aa)
ENSPPAP00000026998Uncharacterized protein. (493 aa)
CX3CL1C-X3-C motif chemokine ligand 1. (397 aa)
LIMS1LIM zinc-binding domain-containing protein. (55 aa)
ABL1Tyrosine-protein kinase. (1149 aa)
ARPC2Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (306 aa)
NINJ1Ninjurin 1. (141 aa)
OLFM4Olfactomedin 4. (510 aa)
CCN1Cellular communication network factor 1. (381 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (766 aa)
ENSPPAP00000025597Uncharacterized protein. (154 aa)
DAG1Dystroglycan 1. (895 aa)
FOXF1Forkhead box F1. (321 aa)
P4HBProtein disulfide-isomerase. (513 aa)
VITVitrin. (693 aa)
TSC1TSC complex subunit 1. (1164 aa)
CEACAM6Carcinoembryonic antigen related cell adhesion molecule 6. (344 aa)
ENSPPAP00000023887LAM_G_DOMAIN domain-containing protein. (932 aa)
EDIL3EGF like repeats and discoidin domains 3. (488 aa)
CDK6Protein kinase domain-containing protein. (84 aa)
EGFLAMEGF like, fibronectin type III and laminin G domains. (984 aa)
NPNTNephronectin. (612 aa)
SFRP1NTR domain-containing protein. (178 aa)
TEKTEK receptor tyrosine kinase. (1124 aa)
EPHA1EPH receptor A1. (965 aa)
NID1Nidogen 1. (1247 aa)
FERMT2Fermitin family member 2. (695 aa)
ITGA3Integrin subunit alpha 3; Belongs to the integrin alpha chain family. (1066 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
ECM2Extracellular matrix protein 2. (701 aa)
RRASRAS related. (176 aa)
LOC100989777Uncharacterized protein. (191 aa)
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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