(40 nodes) Negative regulation of gliogenesis network (Pan paniscus)

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second shell of interactors

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proteins of unknown 3D structure

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Known Interactions

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Predicted Interactions

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Your Input:
	ENSPPAP00000017896	Uncharacterized protein. (214 aa)
	RB1	RB transcriptional corepressor 1. (911 aa)
	LINGO1	Leucine rich repeat and Ig domain containing 1. (620 aa)
	PITX3	Homeobox protein. (208 aa)
	NOG	Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
	ENSPPAP00000002927	CCHC-type domain-containing protein. (202 aa)
	TSPO	Translocator protein. (169 aa)
	ATOH1	Atonal bHLH transcription factor 1. (356 aa)
	DAAM2	Dishevelled associated activator of morphogenesis 2. (1077 aa)
	ABCC8	ATP binding cassette subfamily C member 8. (1582 aa)
	LDLR	Low density lipoprotein receptor. (849 aa)
	SOX10	SRY-box transcription factor 10. (466 aa)
	TP53	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (393 aa)
	NKX6-2	Homeobox domain-containing protein. (230 aa)
	NF1	Neurofibromin 1. (2839 aa)
	SKI	SKI proto-oncogene. (666 aa)
	NF2	Neurofibromin 2. (595 aa)
	DAB1	DAB adaptor protein 1. (588 aa)
	DLX1	Distal-less homeobox 1. (255 aa)
	NR1D1	Nuclear receptor subfamily 1 group D member 1. (614 aa)
	F2	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. (622 aa)
	TREM2	Triggering receptor expressed on myeloid cells 2. (230 aa)
	NKX6-1	Homeobox domain-containing protein. (310 aa)
	CERS2	Ceramide synthase 2. (380 aa)
	KDM4A	Uncharacterized protein. (1064 aa)
	DLX2	Distal-less homeobox 2. (401 aa)
	HES1	Hes family bHLH transcription factor 1. (280 aa)
	NOTCH1	Notch receptor 1. (2573 aa)
	RNF10	Ring finger protein 10. (774 aa)
	NR2E1	Uncharacterized protein. (385 aa)
	MBD1	Methyl-CpG binding domain protein 1. (655 aa)
	LIN28A	Lin-28 homolog A. (209 aa)
	TMEM98	Transmembrane protein 98. (226 aa)
	GPR37L1	G protein-coupled receptor 37 like 1. (481 aa)
	CDKN2B	Cyclin dependent kinase inhibitor 2B. (138 aa)
	SIRT2	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (389 aa)
	CTNNB1	Catenin beta 1. (781 aa)
	DUSP10	Dual specificity phosphatase 10; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (478 aa)
	DICER1	Dicer 1, ribonuclease III; Belongs to the helicase family. Dicer subfamily. (1922 aa)
	ENSPPAP00000022320	Uncharacterized protein. (203 aa)

Your Current Organism:

Pan paniscus

NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABCC8	NKX6-1	ENSPPAP00000007373	ENSPPAP00000034484	ATP binding cassette subfamily C member 8.	Homeobox domain-containing protein.	0.459
ATOH1	HES1	ENSPPAP00000005858	ENSPPAP00000000549	Atonal bHLH transcription factor 1.	Hes family bHLH transcription factor 1.	0.415
ATOH1	NOTCH1	ENSPPAP00000005858	ENSPPAP00000033437	Atonal bHLH transcription factor 1.	Notch receptor 1.	0.475
CDKN2B	NF1	ENSPPAP00000028007	ENSPPAP00000014745	Cyclin dependent kinase inhibitor 2B.	Neurofibromin 1.	0.428
CDKN2B	RB1	ENSPPAP00000028007	ENSPPAP00000000745	Cyclin dependent kinase inhibitor 2B.	RB transcriptional corepressor 1.	0.424
CDKN2B	TP53	ENSPPAP00000028007	ENSPPAP00000011040	Cyclin dependent kinase inhibitor 2B.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.816
CTNNB1	DAAM2	ENSPPAP00000024694	ENSPPAP00000006145	Catenin beta 1.	Dishevelled associated activator of morphogenesis 2.	0.413
CTNNB1	DICER1	ENSPPAP00000024694	ENSPPAP00000024009	Catenin beta 1.	Dicer 1, ribonuclease III; Belongs to the helicase family. Dicer subfamily.	0.458
CTNNB1	NF1	ENSPPAP00000024694	ENSPPAP00000014745	Catenin beta 1.	Neurofibromin 1.	0.416
CTNNB1	NF2	ENSPPAP00000024694	ENSPPAP00000015964	Catenin beta 1.	Neurofibromin 2.	0.703
CTNNB1	NOG	ENSPPAP00000024694	ENSPPAP00000001857	Catenin beta 1.	Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite.	0.559
CTNNB1	NOTCH1	ENSPPAP00000024694	ENSPPAP00000033437	Catenin beta 1.	Notch receptor 1.	0.808
CTNNB1	SIRT2	ENSPPAP00000024694	ENSPPAP00000025973	Catenin beta 1.	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase.	0.699
CTNNB1	SOX10	ENSPPAP00000024694	ENSPPAP00000010343	Catenin beta 1.	SRY-box transcription factor 10.	0.677
CTNNB1	TP53	ENSPPAP00000024694	ENSPPAP00000011040	Catenin beta 1.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.709
DAAM2	CTNNB1	ENSPPAP00000006145	ENSPPAP00000024694	Dishevelled associated activator of morphogenesis 2.	Catenin beta 1.	0.413
DAB1	LDLR	ENSPPAP00000017402	ENSPPAP00000007978	DAB adaptor protein 1.	Low density lipoprotein receptor.	0.722
DICER1	CTNNB1	ENSPPAP00000024009	ENSPPAP00000024694	Dicer 1, ribonuclease III; Belongs to the helicase family. Dicer subfamily.	Catenin beta 1.	0.458
DICER1	ENSPPAP00000022320	ENSPPAP00000024009	ENSPPAP00000022320	Dicer 1, ribonuclease III; Belongs to the helicase family. Dicer subfamily.	Uncharacterized protein.	0.505
DICER1	LIN28A	ENSPPAP00000024009	ENSPPAP00000029767	Dicer 1, ribonuclease III; Belongs to the helicase family. Dicer subfamily.	Lin-28 homolog A.	0.505