STRINGSTRING
APOA1 APOA1 GHRL GHRL ABCA5 ABCA5 ABCG5 ABCG5 ABCG4 ABCG4 OSBPL6 OSBPL6 LDLRAP1 LDLRAP1 FGF19 FGF19 TSKU TSKU SLC10A2 SLC10A2 OSBPL9 OSBPL9 VAPA VAPA HNF1A HNF1A SLC18A2 SLC18A2 SLC22A1 SLC22A1 NPC1 NPC1 SLC5A3 SLC5A3 APOC3 APOC3 RELCH RELCH DRD1 DRD1 ABCC4 ABCC4 SLCO1B7 SLCO1B7 TSPO TSPO OSBPL2 OSBPL2 SLC22A2 SLC22A2 APOB APOB SCARB1 SCARB1 STAR STAR SLCO1C1 SLCO1C1 SLC22A3 SLC22A3 ABCG8 ABCG8 SLC5A12 SLC5A12 SLC10A6 SLC10A6 CD36 CD36 CHRM5 CHRM5 ENSPPAP00000000606 ENSPPAP00000000606 ENSPPAP00000000371 ENSPPAP00000000371 LIPC LIPC APOC2 APOC2 OSBPL10 OSBPL10 SCP2 SCP2 STARD4 STARD4 SLC2A13 SLC2A13 NR0B2 NR0B2 NPC2 NPC2 STARD3NL STARD3NL AQP2 AQP2 ARL8B ARL8B GRAMD1C GRAMD1C ATP8B1 ATP8B1 ARV1 ARV1 ATP8B3 ATP8B3 OSBPL8 OSBPL8 CYP7A1 CYP7A1 STARD3 STARD3 ABCC11 ABCC11 AQP9 AQP9 ENSPPAP00000043045 ENSPPAP00000043045 CEACAM1 CEACAM1 AQP1 AQP1 MECP2 MECP2 VPS4B VPS4B ABCB11 ABCB11 APOM APOM AKR1C1 AKR1C1 SLC10A1 SLC10A1 SERAC1 SERAC1 AKR1C4 AKR1C4 SLC10A7 SLC10A7 LOC100980372 LOC100980372 SLC16A8 SLC16A8 P2RX1 P2RX1 SLCO1B1 SLCO1B1 TPCN2 TPCN2 SLCO2B1 SLCO2B1 VIP VIP SLC16A1 SLC16A1 SLC6A2 SLC6A2 AQP11 AQP11 PARK7 PARK7 CLU CLU SELENOM SELENOM PINK1 PINK1 DRD2 DRD2 SLC6A4 SLC6A4 SLC51B SLC51B ABCA7 ABCA7 LIMA1 LIMA1 SLC29A4 SLC29A4 KANSL1L KANSL1L SOAT1 SOAT1 LOC100979126 LOC100979126 NPC1L1 NPC1L1 RALBP1 RALBP1 SLC51A SLC51A SLC5A11 SLC5A11 LOC100984384 LOC100984384 SPG11 SPG11 MTTP MTTP SLC18A1 SLC18A1 SLC5A8 SLC5A8 ABCC3 ABCC3 ASIC3 ASIC3 SYK SYK OSBP OSBP MAPK15 MAPK15 APOA4 APOA4 OSBPL11 OSBPL11 MSR1 MSR1 SLC10A3 SLC10A3 OSBP2 OSBP2 PRKAA1 PRKAA1 STRA6 STRA6 LCAT LCAT ABCA4 ABCA4 KCNQ1 KCNQ1 GRAMD1B GRAMD1B SLC16A7 SLC16A7 LOC103783188 LOC103783188 SLC22A24 SLC22A24 ENSPPAP00000023305 ENSPPAP00000023305 PRKN PRKN SLCO1A2 SLCO1A2 OSBPL1A OSBPL1A LIPG LIPG EMB EMB AQP10 AQP10 LRP6 LRP6 APOE APOE OSBPL3 OSBPL3 SLC16A3 SLC16A3 CEL CEL OSBPL7 OSBPL7 SLC26A6 SLC26A6 SLC6A3 SLC6A3 LDLR LDLR ABCG1 ABCG1 ABCA12 ABCA12 CETP CETP GRAMD1A GRAMD1A ABCD3 ABCD3 PLTP PLTP ABCA8 ABCA8 OSBPL5 OSBPL5 ENSPPAP00000034951 ENSPPAP00000034951 SOAT2 SOAT2 ABCA1 ABCA1 CFTR CFTR APOA5 APOA5 SLC27A5 SLC27A5 ABCC2 ABCC2 STARD5 STARD5 WNK4 WNK4 LOC100993746 LOC100993746 STX12 STX12 ENSPPAP00000037156 ENSPPAP00000037156 RBP4 RBP4 MFSD10 MFSD10 SLC5A1 SLC5A1 SYT7 SYT7 TSPO2 TSPO2 SLC10A4 SLC10A4 AQP3 AQP3
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
APOA1Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility (By similarity); Belongs to the apolipoprotein A1/A4/E family. (267 aa)
GHRLGhrelin and obestatin prepropeptide. (117 aa)
ABCA5ATP binding cassette subfamily A member 5. (1631 aa)
ABCG5ATP binding cassette subfamily G member 5. (651 aa)
ABCG4ATP binding cassette subfamily G member 4. (646 aa)
OSBPL6Oxysterol-binding protein; Belongs to the OSBP family. (965 aa)
LDLRAP1Low density lipoprotein receptor adaptor protein 1. (295 aa)
FGF19Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (204 aa)
TSKUTsukushi, small leucine rich proteoglycan. (353 aa)
SLC10A2Solute carrier family 10 member 2. (348 aa)
OSBPL9Oxysterol-binding protein; Belongs to the OSBP family. (746 aa)
VAPAVAMP associated protein A. (267 aa)
HNF1AHNF1 homeobox A. (662 aa)
SLC18A2Solute carrier family 18 member A2. (514 aa)
SLC22A1Solute carrier family 22 member 1. (552 aa)
NPC1NPC intracellular cholesterol transporter 1. (1277 aa)
SLC5A3Solute carrier family 5 member 3; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (718 aa)
APOC3Apolipoprotein C3. (99 aa)
RELCHRAB11 binding and LisH domain, coiled-coil and HEAT repeat containing. (1250 aa)
DRD1Dopamine receptor D1; Belongs to the G-protein coupled receptor 1 family. (446 aa)
ABCC4ATP binding cassette subfamily C member 4. (1336 aa)
SLCO1B7Solute carrier organic anion transporter family member. (679 aa)
TSPOTranslocator protein. (169 aa)
OSBPL2Oxysterol-binding protein; Belongs to the OSBP family. (480 aa)
SLC22A2Solute carrier family 22 member 2. (555 aa)
APOBApolipoprotein B. (4535 aa)
SCARB1Uncharacterized protein; Belongs to the CD36 family. (498 aa)
STARSteroidogenic acute regulatory protein. (230 aa)
SLCO1C1Solute carrier organic anion transporter family member. (730 aa)
SLC22A3Solute carrier family 22 member 3. (472 aa)
ABCG8ATP binding cassette subfamily G member 8. (673 aa)
SLC5A12Solute carrier family 5 member 12; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (618 aa)
SLC10A6Solute carrier family 10 member 6. (377 aa)
CD36CD36 molecule; Belongs to the CD36 family. (472 aa)
CHRM5Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (532 aa)
ENSPPAP00000000606Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (325 aa)
ENSPPAP00000000371Rho-GAP domain-containing protein. (252 aa)
LIPCLipase C, hepatic type. (490 aa)
APOC2Uncharacterized protein. (178 aa)
OSBPL10Oxysterol-binding protein; Belongs to the OSBP family. (737 aa)
SCP2Sterol carrier protein 2; Belongs to the thiolase-like superfamily. Thiolase family. (547 aa)
STARD4StAR related lipid transfer domain containing 4. (209 aa)
SLC2A13Solute carrier family 2 member 13; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (587 aa)
NR0B2Nuclear receptor subfamily 0 group B member 2. (257 aa)
NPC2ML domain-containing protein. (221 aa)
STARD3NLSTARD3 N-terminal like. (234 aa)
AQP2Aquaporin 2; Belongs to the MIP/aquaporin (TC 1.A.8) family. (271 aa)
ARL8BADP ribosylation factor like GTPase 8B; Belongs to the small GTPase superfamily. Arf family. (186 aa)
GRAMD1CGRAM domain containing 1C. (662 aa)
ATP8B1Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1251 aa)
ARV1ARV1 homolog, fatty acid homeostasis modulator. (271 aa)
ATP8B3Uncharacterized protein. (1194 aa)
OSBPL8Oxysterol-binding protein; Belongs to the OSBP family. (881 aa)
CYP7A1Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family. (504 aa)
STARD3Uncharacterized protein. (494 aa)
ABCC11ATP binding cassette subfamily C member 11. (1385 aa)
AQP9Aquaporin 9; Belongs to the MIP/aquaporin (TC 1.A.8) family. (295 aa)
ENSPPAP00000043045PIPK domain-containing protein. (255 aa)
CEACAM1Uncharacterized protein. (464 aa)
AQP1Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (269 aa)
MECP2Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). (493 aa)
VPS4BVacuolar protein sorting 4 homolog B; Belongs to the AAA ATPase family. (446 aa)
ABCB11ATP binding cassette subfamily B member 11. (1321 aa)
APOMApolipoprotein M. (188 aa)
AKR1C1Aldo-keto reductase family 1 member C1. (295 aa)
SLC10A1Solute carrier family 10 member 1. (349 aa)
SERAC1Serine active site containing 1. (654 aa)
AKR1C4Aldo-keto reductase family 1 member C4. (323 aa)
SLC10A7Sodium/bile acid cotransporter; Does not show transport activity towards bile acids or steroid sulfates; Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family. (358 aa)
LOC100980372Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (517 aa)
SLC16A8Solute carrier family 16 member 8. (504 aa)
P2RX1P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (399 aa)
SLCO1B1Solute carrier organic anion transporter family member. (691 aa)
TPCN2Two pore segment channel 2. (752 aa)
SLCO2B1Solute carrier organic anion transporter family member. (709 aa)
VIPVasoactive intestinal peptide. (170 aa)
SLC16A1Solute carrier family 16 member 1. (500 aa)
SLC6A2Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (617 aa)
AQP11Aquaporin; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes. (271 aa)
PARK7Parkinsonism associated deglycase. (189 aa)
CLUClusterin; Functions as extracellular chaperone that prevents aggregation of non native proteins. Prevents stress-induced aggregation of blood plasma proteins. (449 aa)
SELENOMSelenoprotein M. (124 aa)
PINK1PTEN induced kinase 1. (554 aa)
DRD2Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. (490 aa)
SLC6A4Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (630 aa)
SLC51BSolute carrier family 51 beta subunit. (128 aa)
ABCA7ATP binding cassette subfamily A member 7. (2146 aa)
LIMA1LIM domain and actin binding 1. (760 aa)
SLC29A4Solute carrier family 29 member 4. (515 aa)
KANSL1LKAT8 regulatory NSL complex subunit 1 like. (987 aa)
SOAT1O-acyltransferase. (550 aa)
LOC100979126Uncharacterized protein; Belongs to the AAA ATPase family. (462 aa)
NPC1L1NPC1 like intracellular cholesterol transporter 1. (1359 aa)
RALBP1RalA binding protein 1. (655 aa)
SLC51ASolute carrier family 51 alpha subunit. (340 aa)
SLC5A11Solute carrier family 5 member 11; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (609 aa)
LOC100984384COesterase domain-containing protein. (369 aa)
SPG11SPG11 vesicle trafficking associated, spatacsin. (2443 aa)
MTTPMicrosomal triglyceride transfer protein. (921 aa)
SLC18A1Solute carrier family 18 member A1. (508 aa)
SLC5A8Solute carrier family 5 member 8; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (610 aa)
ABCC3ATP binding cassette subfamily C member 3. (1544 aa)
ASIC3Acid sensing ion channel subunit 3; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (549 aa)
SYKTyrosine-protein kinase. (635 aa)
OSBPOxysterol-binding protein; Belongs to the OSBP family. (757 aa)
MAPK15Mitogen-activated protein kinase. (544 aa)
APOA4Apolipoprotein A4. (396 aa)
OSBPL11Oxysterol-binding protein; Belongs to the OSBP family. (747 aa)
MSR1Macrophage scavenger receptor 1. (460 aa)
SLC10A3Solute carrier family 10 member 3. (532 aa)
OSBP2Oxysterol binding protein 2. (903 aa)
PRKAA1Non-specific serine/threonine protein kinase. (574 aa)
STRA6Stimulated by retinoic acid 6. (706 aa)
LCATLecithin-cholesterol acyltransferase. (440 aa)
ABCA4ATP binding cassette subfamily A member 4. (2159 aa)
KCNQ1Ion_trans domain-containing protein; Belongs to the potassium channel family. (557 aa)
GRAMD1BGRAM domain containing 1B. (877 aa)
SLC16A7Solute carrier family 16 member 7. (478 aa)
LOC103783188Aldo_ket_red domain-containing protein. (205 aa)
SLC22A24Solute carrier family 22 member 24. (522 aa)
ENSPPAP00000023305DJ-1_PfpI domain-containing protein. (168 aa)
PRKNE3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (428 aa)
SLCO1A2Solute carrier organic anion transporter family member. (649 aa)
OSBPL1AOxysterol-binding protein; Belongs to the OSBP family. (950 aa)
LIPGLipase G, endothelial type. (500 aa)
EMBEmbigin. (323 aa)
AQP10Aquaporin 10; Belongs to the MIP/aquaporin (TC 1.A.8) family. (301 aa)
LRP6Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1613 aa)
APOEApolipoprotein E. (317 aa)
OSBPL3Oxysterol-binding protein; Belongs to the OSBP family. (887 aa)
SLC16A3Solute carrier family 16 member 3. (465 aa)
CELCarboxyl ester lipase. (660 aa)
OSBPL7Oxysterol-binding protein; Belongs to the OSBP family. (842 aa)
SLC26A6Solute carrier family 26 member 6. (761 aa)
SLC6A3Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (620 aa)
LDLRLow density lipoprotein receptor. (849 aa)
ABCG1ABC transporter domain-containing protein. (807 aa)
ABCA12ATP binding cassette subfamily A member 12. (2595 aa)
CETPCholesteryl ester transfer protein; Involved in the transfer of neutral lipids, including cholesteryl ester and triglyceride, among lipoprotein particles. Allows the net movement of cholesteryl ester from high density lipoproteins/HDL to triglyceride-rich very low density lipoproteins/VLDL, and the equimolar transport of triglyceride from VLDL to HDL; Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family. (466 aa)
GRAMD1AGRAM domain containing 1A. (812 aa)
ABCD3ATP binding cassette subfamily D member 3. (659 aa)
PLTPPhospholipid transfer protein. (493 aa)
ABCA8ATP binding cassette subfamily A member 8. (1621 aa)
OSBPL5Oxysterol-binding protein; Belongs to the OSBP family. (879 aa)
ENSPPAP00000034951Uncharacterized protein. (91 aa)
SOAT2O-acyltransferase. (526 aa)
ABCA1ATP binding cassette subfamily A member 1. (2264 aa)
CFTRCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1480 aa)
APOA5Apolipoprotein A5. (366 aa)
SLC27A5Solute carrier family 27 member 5. (690 aa)
ABCC2ATP binding cassette subfamily C member 2. (1537 aa)
STARD5StAR related lipid transfer domain containing 5. (213 aa)
WNK4WNK lysine deficient protein kinase 4. (1278 aa)
LOC100993746Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (304 aa)
STX12Syntaxin 12; Belongs to the syntaxin family. (276 aa)
ENSPPAP00000037156Uncharacterized protein. (167 aa)
RBP4Retinol-binding protein; Retinol-binding protein that mediates retinol transport in blood plasma. (201 aa)
MFSD10Major facilitator superfamily domain containing 10. (455 aa)
SLC5A1Solute carrier family 5 member 1; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (664 aa)
SYT7Uncharacterized protein. (686 aa)
TSPO2Translocator protein 2. (170 aa)
SLC10A4Solute carrier family 10 member 4. (377 aa)
AQP3Aquaporin 3 (Gill blood group); Belongs to the MIP/aquaporin (TC 1.A.8) family. (292 aa)
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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