Your Input: | |
| | CTNND2 | Uncharacterized protein. (817 aa) |
| | SFRP4 | Secreted frizzled related protein 4. (368 aa) |
| | DKK4 | Dickkopf WNT signaling pathway inhibitor 4. (224 aa) |
| | STRN | Striatin. (627 aa) |
| | WNT3A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (359 aa) |
| | SHH | Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (414 aa) |
| | TIAM1 | T cell lymphoma invasion and metastasis 1. (1591 aa) |
| | LOC100989777 | Uncharacterized protein. (191 aa) |
| | AMER3 | APC membrane recruitment protein 3. (861 aa) |
| | AMER2 | Uncharacterized protein. (466 aa) |
| | WNT9B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (495 aa) |
| | WLS | Wnt ligand secretion mediator. (541 aa) |
| | MARK2 | Non-specific serine/threonine protein kinase. (788 aa) |
| | PORCN | Porcupine O-acyltransferase; Belongs to the membrane-bound acyltransferase family. (461 aa) |
| | RAC1 | Uncharacterized protein. (224 aa) |
| | ENSPPAP00000019393 | Protein kinase domain-containing protein. (777 aa) |
| | MED12 | Mediator complex subunit 12. (2182 aa) |
| | SFRP2 | Secreted frizzled related protein 2. (295 aa) |
| | PIAS4 | Protein inhibitor of activated STAT 4. (573 aa) |
| | APC | APC regulator of WNT signaling pathway. (2844 aa) |
| | FZD3 | Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa) |
| | USP34 | Ubiquitin specific peptidase 34; Belongs to the peptidase C19 family. (3536 aa) |
| | MACF1 | Uncharacterized protein. (7567 aa) |
| | SCYL2 | SCY1 like pseudokinase 2. (933 aa) |
| | LOC100993131 | Cell division control protein 42 homolog. (191 aa) |
| | NR4A2 | Nuclear receptor subfamily 4 group A member 2. (598 aa) |
| | SMURF1 | E3 ubiquitin-protein ligase. (752 aa) |
| | CCDC88C | Coiled-coil domain containing 88C. (2019 aa) |
| | ENSPPAP00000017361 | Uncharacterized protein. (81 aa) |
| | FRZB | Frizzled related protein. (325 aa) |
| | MARK4 | Non-specific serine/threonine protein kinase. (752 aa) |
| | SIAH1 | E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (313 aa) |
| | SFRP5 | Secreted frizzled related protein 5. (311 aa) |
| | OTULIN | OTU deubiquitinase with linear linkage specificity. (342 aa) |
| | CBY1 | Chibby family member 1, beta catenin antagonist. (169 aa) |
| | RSPO4 | Uncharacterized protein. (301 aa) |
| | DISC1 | DISC1 scaffold protein. (835 aa) |
| | CCDC90B | Coiled-coil domain containing 90B. (254 aa) |
| | DVL2 | Dishevelled segment polarity protein 2. (736 aa) |
| | CELSR3 | Cadherin EGF LAG seven-pass G-type receptor 3; Belongs to the G-protein coupled receptor 2 family. (3324 aa) |
| | AXIN1 | Axin 1. (862 aa) |
| | PYGO1 | Pygopus family PHD finger 1. (423 aa) |
| | CDC42 | Uncharacterized protein. (191 aa) |
| | PKD2 | Polycystin 2, transient receptor potential cation channel. (788 aa) |
| | TCF7L1 | Transcription factor 7 like 1. (560 aa) |
| | NLK | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (527 aa) |
| | FOXO1 | Fork-head domain-containing protein. (527 aa) |
| | KREMEN1 | Kremen protein; Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6. (470 aa) |
| | DAAM1 | Dishevelled associated activator of morphogenesis 1. (1078 aa) |
| | BMP2 | Bone morphogenetic protein 2. (396 aa) |
| | FZD7 | Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family. (571 aa) |
| | WIF1 | WNT inhibitory factor 1. (379 aa) |
| | WNT2 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa) |
| | MBD2 | MBD domain-containing protein. (365 aa) |
| | RTF1 | RTF1 homolog, Paf1/RNA polymerase II complex component. (667 aa) |
| | WNT7A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (349 aa) |
| | TCF7L2 | Transcription factor 7 like 2. (555 aa) |
| | EDN1 | Endothelin 1. (212 aa) |
| | CPE | Carboxypeptidase E. (465 aa) |
| | CALCOCO1 | Calcium binding and coiled-coil domain 1. (691 aa) |
| | LRRC45 | Leucine rich repeat containing 45. (670 aa) |
| | TNKS | Poly [ADP-ribose] polymerase. (1327 aa) |
| | RSPO2 | R-spondin 2. (243 aa) |
| | PTEN | Uncharacterized protein. (542 aa) |
| | CUL3 | Cullin 3; Belongs to the cullin family. (795 aa) |
| | LGR6 | Leucine rich repeat containing G protein-coupled receptor 6. (961 aa) |
| | RARG | Retinoic acid receptor gamma. (464 aa) |
| | DAB2 | DAB adaptor protein 2. (752 aa) |
| | INVS | Inversin. (1029 aa) |
| | ENSPPAP00000011329 | FCP1 homology domain-containing protein. (218 aa) |
| | ENSPPAP00000011186 | Homeobox domain-containing protein. (218 aa) |
| | LGR4 | Leucine rich repeat containing G protein-coupled receptor 4. (935 aa) |
| | NDP | Norrin cystine knot growth factor NDP. (133 aa) |
| | CTHRC1 | Collagen triple helix repeat containing 1. (243 aa) |
| | CELSR2 | Cadherin EGF LAG seven-pass G-type receptor 2; Belongs to the G-protein coupled receptor 2 family. (2908 aa) |
| | GRK5 | G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (590 aa) |
| | FZD9 | Frizzled class receptor 9; Belongs to the G-protein coupled receptor Fz/Smo family. (517 aa) |
| | TMEM198 | Transmembrane protein 198. (360 aa) |
| | WNT16 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa) |
| | UBAC2 | UBA domain containing 2. (344 aa) |
| | BCL9 | BCL9 transcription coactivator. (1426 aa) |
| | CD24 | CD24 molecule. (129 aa) |
| | CSNK1G3 | Casein kinase 1 gamma 3; Belongs to the protein kinase superfamily. (455 aa) |
| | SIAH2 | E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (271 aa) |
| | HMGXB4 | HMG-box containing 4. (600 aa) |
| | CYLD | CYLD lysine 63 deubiquitinase; Belongs to the peptidase C19 family. (956 aa) |
| | RYK | Uncharacterized protein. (475 aa) |
| | LRP5 | LDL receptor related protein 5. (1839 aa) |
| | HESX1 | Homeobox expressed in ES cells 1; Required for the normal development of the forebrain, eyes and other anterior structures such as the olfactory placodes and pituitary gland. Possible transcriptional repressor. Binds to the palindromic PIII sequence, 5'-AGCTTGAGTCTAATTGAATTAACTGTAC-3'. HESX1 and PROP1 bind as heterodimers on this palindromic site, and, in vitro, HESX1 can antagonize PROP1 activation (By similarity). (185 aa) |
| | GRHL3 | Grainyhead like transcription factor 3. (626 aa) |
| | EDNRB | Endothelin receptor type B; Belongs to the G-protein coupled receptor 1 family. (532 aa) |
| | LOC100978688 | G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (486 aa) |
| | CTNNBIP1 | Catenin beta interacting protein 1. (81 aa) |
| | STK4 | Serine/threonine kinase 4. (487 aa) |
| | PAF1 | PAF1 homolog, Paf1/RNA polymerase II complex component. (533 aa) |
| | ENSPPAP00000008445 | TLE_N domain-containing protein. (90 aa) |
| | WNT5A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (366 aa) |
| | TLE3 | TLE family member 3, transcriptional corepressor. (774 aa) |
| | FAM53B | Family with sequence similarity 53 member B. (422 aa) |
| | ENSPPAP00000007691 | BTB domain-containing protein. (527 aa) |
| | GATA3 | GATA binding protein 3. (444 aa) |
| | LOC100968831 | Uncharacterized protein. (212 aa) |
| | WNT2B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (391 aa) |
| | CCNY | Cyclin Y; Belongs to the cyclin family. (341 aa) |
| | C12orf43 | Chromosome 12 open reading frame 43. (263 aa) |
| | PLPP3 | acidPPc domain-containing protein. (311 aa) |
| | PRKAA2 | Non-specific serine/threonine protein kinase. (542 aa) |
| | ARL6 | ADP ribosylation factor like GTPase 6; Belongs to the small GTPase superfamily. Arf family. (203 aa) |
| | PYGO2 | Pygopus family PHD finger 2. (368 aa) |
| | APCDD1 | APC down-regulated 1. (513 aa) |
| | SLC9A3R1 | Na(+)/H(+) exchange regulatory cofactor NHE-RF; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. (358 aa) |
| | APC2 | Uncharacterized protein. (1779 aa) |
| | MESD | Mesoderm development LRP chaperone. (234 aa) |
| | WNT5B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (359 aa) |
| | AMER1 | APC membrane recruitment protein 1. (1136 aa) |
| | WNT11 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa) |
| | ROR1 | Receptor tyrosine kinase like orphan receptor 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (937 aa) |
| | WNT6 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa) |
| | WNT8A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (369 aa) |
| | RSPO3 | R-spondin 3. (291 aa) |
| | WNT4 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (342 aa) |
| | DIXDC1 | DIX domain containing 1. (683 aa) |
| | LOC100980541 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (507 aa) |
| | TLE5 | TLE family member 5, transcriptional modulator. (264 aa) |
| | ZBTB33 | Zinc finger and BTB domain containing 33. (672 aa) |
| | FGF9 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa) |
| | SHISA6 | Shisa family member 6. (461 aa) |
| | TAX1BP3 | Tax1-binding protein 3; May regulate a number of protein-protein interactions by competing for PDZ domain binding sites. (124 aa) |
| | DLX3 | Distal-less homeobox 3. (287 aa) |
| | MCC | MCC regulator of WNT signaling pathway. (910 aa) |
| | LZTS2 | Leucine zipper putative tumor suppressor 2; Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. May negatively regulate axonal outgrowth by preventing the formation of microtubule bundles that are necessary for transport within the elongating axon. Negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta- catenin. (669 aa) |
| | SOX17 | SRY-box transcription factor 17. (428 aa) |
| | FZD5 | Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. (585 aa) |
| | CSNK2B | Uncharacterized protein. (298 aa) |
| | WNT1 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa) |
| | VAX2 | Ventral anterior homeobox 2. (290 aa) |
| | RNF146 | Ring finger protein 146. (359 aa) |
| | FBXW4 | F-box and WD repeat domain containing 4. (395 aa) |
| | CSNK1D | Casein kinase 1 delta; Belongs to the protein kinase superfamily. (427 aa) |
| | DAAM2 | Dishevelled associated activator of morphogenesis 2. (1077 aa) |
| | LDB1 | LIM domain binding 1. (410 aa) |
| | PPP1CA | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (334 aa) |
| | DVL1 | Dishevelled segment polarity protein 1. (674 aa) |
| | VPS35 | Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting. (796 aa) |
| | EXT1 | Exostosin glycosyltransferase 1; Belongs to the glycosyltransferase 47 family. (746 aa) |
| | CSNK1A1L | Casein kinase 1 alpha 1 like; Belongs to the protein kinase superfamily. (337 aa) |
| | ENSPPAP00000004673 | Uncharacterized protein. (176 aa) |
| | VANGL2 | Vang-like protein. (521 aa) |
| | NKD1 | EF-hand domain-containing protein. (634 aa) |
| | KLF4 | Kruppel like factor 4. (477 aa) |
| | TRABD2B | TraB domain containing 2B. (483 aa) |
| | LRP4 | LDL receptor related protein 4. (1857 aa) |
| | LMBR1L | Limb development membrane protein 1 like; Belongs to the LIMR family. (489 aa) |
| | YAP1 | Yes associated protein 1. (512 aa) |
| | LEF1 | Lymphoid enhancer binding factor 1. (399 aa) |
| | SMURF2 | E3 ubiquitin-protein ligase. (790 aa) |
| | PRICKLE1 | Prickle planar cell polarity protein 1. (831 aa) |
| | CDK14 | Cyclin dependent kinase 14; Belongs to the protein kinase superfamily. (469 aa) |
| | CTNND1 | Catenin delta 1. (975 aa) |
| | CCN4 | Cellular communication network factor 4. (367 aa) |
| | AMOTL2 | Angiomotin like 2. (764 aa) |
| | RECK | Reversion inducing cysteine rich protein with kazal motifs. (970 aa) |
| | ARHGEF19 | Rho guanine nucleotide exchange factor 19. (804 aa) |
| | RSPO1 | R-spondin 1. (267 aa) |
| | MYOC | Myocilin. (504 aa) |
| | HBP1 | HMG-box transcription factor 1. (526 aa) |
| | KLHL12 | Kelch like family member 12. (568 aa) |
| | DDX3X | DEAD-box helicase 3 X-linked; Belongs to the DEAD box helicase family. (733 aa) |
| | DKK3 | Dickkopf WNT signaling pathway inhibitor 3. (350 aa) |
| | KREMEN2 | Kremen protein; Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6. (462 aa) |
| | DVL3 | Dishevelled segment polarity protein 3. (718 aa) |
| | RAB5A | RAB5A, member RAS oncogene family. (216 aa) |
| | IFT80 | Intraflagellar transport 80. (771 aa) |
| | BCL9L | BCL9 like. (1483 aa) |
| | ADGRA2 | Adhesion G protein-coupled receptor A2; Belongs to the G-protein coupled receptor 2 family. (1306 aa) |
| | WNT10A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (414 aa) |
| | MITF | Melanocyte inducing transcription factor. (519 aa) |
| | GID8 | GID complex subunit 8 homolog. (228 aa) |
| | FBXW11 | F-box and WD repeat domain containing 11. (563 aa) |
| | CSNK1A1 | Casein kinase 1 alpha 1; Belongs to the protein kinase superfamily. (365 aa) |
| | AMFR | Autocrine motility factor receptor. (564 aa) |
| | CCAR2 | Cell cycle and apoptosis regulator 2. (930 aa) |
| | DACT3 | Uncharacterized protein. (180 aa) |
| | GRK6 | G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (558 aa) |
| | LATS2 | Non-specific serine/threonine protein kinase. (1088 aa) |
| | GSK3B | Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (481 aa) |
| | STK3 | Serine/threonine kinase 3. (467 aa) |
| | JUP | Junction plakoglobin. (745 aa) |
| | LRRK2 | Leucine rich repeat kinase 2. (2527 aa) |
| | EPM2A | Uncharacterized protein. (193 aa) |
| | GSC | Homeobox protein goosecoid; Regulates chordin (CHRD). May play a role in spatial programing within discrete embryonic fields or lineage compartments during organogenesis. In concert with NKX3-2, plays a role in defining the structural components of the middle ear; required for the development of the entire tympanic ring (By similarity). Probably involved in the regulatory networks that define neural crest cell fate specification and determine mesoderm cell lineages in mammals (By similarity); Belongs to the paired homeobox family. Bicoid subfamily. (257 aa) |
| | SENP2 | ULP_PROTEASE domain-containing protein. (589 aa) |
| | WNT9A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (362 aa) |
| | TNKS2 | Poly [ADP-ribose] polymerase. (1166 aa) |
| | NXN | Thioredoxin domain-containing protein. (328 aa) |
| | TLE4 | TLE family member 4, transcriptional corepressor. (790 aa) |
| | ENSPPAP00000034729 | ULP_PROTEASE domain-containing protein. (580 aa) |
| | LEO1 | LEO1 homolog, Paf1/RNA polymerase II complex component. (666 aa) |
| | CHD8 | Chromodomain-helicase-DNA-binding protein 8; DNA helicase that acts as a chromatin remodeling factor and regulates transcription. Acts as a transcription repressor by remodeling chromatin structure and recruiting histone H1 to target genes. Suppresses p53/TP53-mediated apoptosis by recruiting histone H1 and preventing p53/TP53 transactivation activity. Acts as a negative regulator of Wnt signaling pathway by regulating beta-catenin (CTNNB1) activity. Negatively regulates CTNNB1-targeted gene expression by being recruited specifically to the promoter regions of several CTNNB1 responsive [...] (2573 aa) |
| | CTR9 | CTR9 homolog, Paf1/RNA polymerase II complex component. (1173 aa) |
| | FZD4 | Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (540 aa) |
| | WNT8B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa) |
| | TRABD2A | TraB domain containing 2A. (505 aa) |
| | CSNK2A2 | Casein kinase 2 alpha 2; Belongs to the protein kinase superfamily. (323 aa) |
| | LOC100983971 | Uncharacterized protein. (121 aa) |
| | PLCG2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa) |
| | CCNE1 | Cyclin E1; Belongs to the cyclin family. (437 aa) |
| | CCDC88A | Coiled-coil domain containing 88A. (1824 aa) |
| | PTK7 | Protein tyrosine kinase 7 (inactive); Belongs to the protein kinase superfamily. Tyr protein kinase family. (1078 aa) |
| | LOC100995377 | Uncharacterized protein. (557 aa) |
| | ENSPPAP00000033311 | Protein kinase domain-containing protein. (305 aa) |
| | FGF10 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa) |
| | LRRFIP2 | LRR binding FLII interacting protein 2. (721 aa) |
| | PPP2R3A | Protein phosphatase 2 regulatory subunit B''alpha. (1150 aa) |
| | SOST | Sclerostin. (213 aa) |
| | NDRG2 | NDRG family member 2. (371 aa) |
| | BRD7 | Bromodomain containing 7. (644 aa) |
| | CDH3 | Cadherin 3; Cadherins are calcium-dependent cell adhesion proteins. (829 aa) |
| | ETV2 | ETS variant 2. (342 aa) |
| | TLE2 | TLE family member 2, transcriptional corepressor. (606 aa) |
| | DKK2 | Dickkopf WNT signaling pathway inhibitor 2. (259 aa) |
| | MAGI2 | Membrane associated guanylate kinase, WW and PDZ domain containing 2. (1256 aa) |
| | WWOX | WW domain containing oxidoreductase. (414 aa) |
| | VANGL1 | Vang-like protein. (524 aa) |
| | ENSPPAP00000029665 | Uncharacterized protein. (115 aa) |
| | GPC6 | Glypican 6; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (501 aa) |
| | CELSR1 | Cadherin EGF LAG seven-pass G-type receptor 1; Belongs to the G-protein coupled receptor 2 family. (2933 aa) |
| | SDC1 | Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (334 aa) |
| | EDNRA | Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (427 aa) |
| | WNT3 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa) |
| | BCL7B | Uncharacterized protein. (236 aa) |
| | EDA | TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (223 aa) |
| | TLE1 | TLE family member 1, transcriptional corepressor. (779 aa) |
| | LOC106634746 | Uncharacterized protein. (211 aa) |
| | PRICKLE2 | Prickle planar cell polarity protein 2. (886 aa) |
| | CAV1 | Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa) |
| | AMOTL1 | Angiomotin like 1. (960 aa) |
| | TNIK | TRAF2 and NCK interacting kinase. (1360 aa) |
| | TGFB1I1 | Transforming growth factor beta-1-induced transcript 1 protein; Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways. (470 aa) |
| | GSK3A | Glycogen synthase kinase 3 alpha; Belongs to the protein kinase superfamily. (463 aa) |
| | CSNK1G1 | Casein kinase 1 gamma 1; Belongs to the protein kinase superfamily. (475 aa) |
| | WDR61 | WD repeat domain 61. (305 aa) |
| | CELA1 | Chymotrypsin like elastase 1; Belongs to the peptidase S1 family. (258 aa) |
| | WNT7B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa) |
| | ZRANB1 | Zinc finger RANBP2-type containing 1. (734 aa) |
| | ENSPPAP00000026571 | Uncharacterized protein. (67 aa) |
| | GPC4 | Glypican 4; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (556 aa) |
| | NOTUM | Uncharacterized protein. (252 aa) |
| | CPZ | Carboxypeptidase Z. (747 aa) |
| | HHEX | Hematopoietically expressed homeobox. (255 aa) |
| | TMEM131L | Transmembrane 131 like. (1617 aa) |
| | PRKAA1 | Non-specific serine/threonine protein kinase. (574 aa) |
| | ENSPPAP00000025550 | CXXC-type domain-containing protein. (173 aa) |
| | TMEM88 | Transmembrane protein 88. (159 aa) |
| | WNT10B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa) |
| | CTDNEP1 | CTD nuclear envelope phosphatase 1. (244 aa) |
| | DRAXIN | Draxin; Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway. (349 aa) |
| | CTNNB1 | Catenin beta 1. (781 aa) |
| | DDB1 | Damage specific DNA binding protein 1. (1147 aa) |
| | FZD6 | Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family. (706 aa) |
| | MARK1 | Non-specific serine/threonine protein kinase. (795 aa) |
| | DACT1 | Dishevelled binding antagonist of beta catenin 1. (750 aa) |
| | NKD2 | NKD inhibitor of WNT signaling pathway 2. (416 aa) |
| | ROR2 | Receptor tyrosine kinase like orphan receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (982 aa) |
| | CDC73 | Cell division cycle 73. (531 aa) |
| | LRP6 | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1613 aa) |
| | BTRC | Beta-transducin repeat containing E3 ubiquitin protein ligase. (605 aa) |
| | SOSTDC1 | Sclerostin domain containing 1. (230 aa) |
| | RNF43 | RING-type domain-containing protein. (783 aa) |
| | DKK1 | Dickkopf WNT signaling pathway inhibitor 1. (289 aa) |
| | ENSPPAP00000022416 | Uncharacterized protein. (68 aa) |
| | SFRP1 | NTR domain-containing protein. (178 aa) |
| | TCF7 | HMG box domain-containing protein. (391 aa) |
| | DDIT3 | DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (169 aa) |
| | ISL1 | ISL LIM homeobox 1. (349 aa) |
| | AXIN2 | Axin 2. (843 aa) |
| | FERMT2 | Fermitin family member 2. (695 aa) |
