(60 nodes) snRNA metabolic process network (Pan paniscus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	EXOSC9	Exosome component 9. (456 aa)
	ICE2	Interactor of little elongation complex ELL subunit 2. (982 aa)
	INTS6	Integrator complex subunit 6. (875 aa)
	INTS10	Integrator complex subunit 10. (736 aa)
	INTS13	Integrator complex subunit 13. (706 aa)
	SNAPC3	Small nuclear RNA activating complex polypeptide 3. (411 aa)
	ELL2	Elongation factor for RNA polymerase II 2. (640 aa)
	ENSPPAP00000004436	Uncharacterized protein. (203 aa)
	DKC1	Dyskerin pseudouridine synthase 1. (514 aa)
	EXOSC5	Exosome component 5. (235 aa)
	LOC100980688	Uncharacterized protein. (303 aa)
	ELL3	Elongation factor for RNA polymerase II 3. (397 aa)
	EXOSC8	Exosome component 8. (276 aa)
	ENSPPAP00000008094	Uncharacterized protein. (447 aa)
	RBM7	RNA binding motif protein 7. (267 aa)
	ZC3H8	Zinc finger CCCH-type containing 8. (291 aa)
	CDK7	Cyclin dependent kinase 7; Belongs to the protein kinase superfamily. (346 aa)
	INTS5	Integrator complex subunit 5. (1019 aa)
	ENSPPAP00000010813	INT_SG_DDX_CT_C domain-containing protein. (725 aa)
	NHP2	Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (153 aa)
	LOC103785739	Uncharacterized protein. (146 aa)
	ELL	Elongation factor for RNA polymerase II. (621 aa)
	INTS1	Integrator complex subunit 1. (2194 aa)
	EXOSC3	Exosome component 3. (275 aa)
	METTL16	U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase; RNA N6-methyltransferase that methylates adenosine residues of a subset of RNAs and plays a key role in S-adenosyl-L-methionine homeostasis by regulating expression of MAT2A transcripts. Able to N6- methylate a subset of mRNAs and U6 small nuclear RNAs (U6 snRNAs). In contrast to the METTL3-METTL14 heterodimer, only able to methylate a limited number of RNAs: requires both a 5'UACAGAGAA-3' nonamer sequence and a specific RNA structure. In presence of S-adenosyl-L-methionine, binds the 3'-UTR region of MAT2A mRNA and specifical [...] (589 aa)
	INTS14	Integrator complex subunit 14. (545 aa)
	METTL4	Methyltransferase like 4; Belongs to the MT-A70-like family. (472 aa)
	ZCCHC8	CCHC-type domain-containing protein. (707 aa)
	ENSPPAP00000016518	Uncharacterized protein. (614 aa)
	MEPCE	Methylphosphate capping enzyme. (688 aa)
	LOC100979609	INT_SG_DDX_CT_C domain-containing protein. (751 aa)
	SNAPC2	Small nuclear RNA activating complex polypeptide 2. (332 aa)
	USPL1	Ubiquitin specific peptidase like 1. (1093 aa)
	SNAPC1	Small nuclear RNA activating complex polypeptide 1. (368 aa)
	INTS8	Integrator complex subunit 8. (995 aa)
	INTS3	Integrator complex subunit 3. (1042 aa)
	INTS6L	Integrator complex subunit 6 like. (898 aa)
	INTS9	Integrator complex subunit 9. (667 aa)
	NOP10	NOP10 ribonucleoprotein. (64 aa)
	EXOSC2	Exosome component 2. (293 aa)
	RPAP2	RNA polymerase II associated protein 2. (612 aa)
	INTS4	Uncharacterized protein. (160 aa)
	EXOSC4	Exosome component 4. (245 aa)
	SNAPC4	Small nuclear RNA activating complex polypeptide 4. (1459 aa)
	TUT1	RRM domain-containing protein. (912 aa)
	INTS11	Integrator complex subunit 11. (606 aa)
	ZCCHC7	Uncharacterized protein. (339 aa)
	EXOSC10	Exosome component 10. (890 aa)
	LARP7	La ribonucleoprotein domain family member 7. (588 aa)
	MTREX	Mtr4 exosome RNA helicase. (1042 aa)
	ICE1	Interactor of little elongation complex ELL subunit 1. (2266 aa)
	ENSPPAP00000034007	Protein kinase domain-containing protein. (324 aa)
	INTS12	Integrator complex subunit 12. (462 aa)
	SNAPC5	Small nuclear RNA activating complex polypeptide 5. (98 aa)
	USB1	U6 snRNA phosphodiesterase; Phosphodiesterase responsible for the U6 snRNA 3' end processing. Acts as an exoribonuclease (RNase) responsible for trimming the poly(U) tract of the last nucleotides in the pre-U6 snRNA molecule, leading to the formation of mature U6 snRNA 3' end-terminated with a 2',3'-cyclic phosphate; Belongs to the 2H phosphoesterase superfamily. USB1 family. (265 aa)
	INTS2	Integrator complex subunit 2. (1174 aa)
	INTS7	Integrator complex subunit 7. (962 aa)
	TOE1	Target of EGR1, exonuclease. (523 aa)
	EXOSC7	Exosome component 7. (291 aa)
	ENSPPAP00000042592	NARG2_C domain-containing protein. (686 aa)

Your Current Organism:

Pan paniscus

NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDK7	SNAPC1	ENSPPAP00000010123	ENSPPAP00000019851	Cyclin dependent kinase 7; Belongs to the protein kinase superfamily.	Small nuclear RNA activating complex polypeptide 1.	0.480
DKC1	EXOSC10	ENSPPAP00000005887	ENSPPAP00000030845	Dyskerin pseudouridine synthase 1.	Exosome component 10.	0.427
DKC1	MTREX	ENSPPAP00000005887	ENSPPAP00000032989	Dyskerin pseudouridine synthase 1.	Mtr4 exosome RNA helicase.	0.470
DKC1	NHP2	ENSPPAP00000005887	ENSPPAP00000010922	Dyskerin pseudouridine synthase 1.	Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family.	0.999
DKC1	NOP10	ENSPPAP00000005887	ENSPPAP00000023192	Dyskerin pseudouridine synthase 1.	NOP10 ribonucleoprotein.	0.999
DKC1	USB1	ENSPPAP00000005887	ENSPPAP00000038854	Dyskerin pseudouridine synthase 1.	U6 snRNA phosphodiesterase; Phosphodiesterase responsible for the U6 snRNA 3' end processing. Acts as an exoribonuclease (RNase) responsible for trimming the poly(U) tract of the last nucleotides in the pre-U6 snRNA molecule, leading to the formation of mature U6 snRNA 3' end-terminated with a 2',3'-cyclic phosphate; Belongs to the 2H phosphoesterase superfamily. USB1 family.	0.453
ELL	ELL2	ENSPPAP00000011877	ENSPPAP00000004367	Elongation factor for RNA polymerase II.	Elongation factor for RNA polymerase II 2.	0.803
ELL	ELL3	ENSPPAP00000011877	ENSPPAP00000007578	Elongation factor for RNA polymerase II.	Elongation factor for RNA polymerase II 3.	0.961
ELL	ENSPPAP00000016518	ENSPPAP00000011877	ENSPPAP00000016518	Elongation factor for RNA polymerase II.	Uncharacterized protein.	0.771
ELL	ENSPPAP00000042592	ENSPPAP00000011877	ENSPPAP00000042592	Elongation factor for RNA polymerase II.	NARG2_C domain-containing protein.	0.789
ELL	ICE1	ENSPPAP00000011877	ENSPPAP00000033974	Elongation factor for RNA polymerase II.	Interactor of little elongation complex ELL subunit 1.	0.449
ELL	ICE2	ENSPPAP00000011877	ENSPPAP00000001133	Elongation factor for RNA polymerase II.	Interactor of little elongation complex ELL subunit 2.	0.789
ELL	INTS11	ENSPPAP00000011877	ENSPPAP00000030201	Elongation factor for RNA polymerase II.	Integrator complex subunit 11.	0.454
ELL	INTS3	ENSPPAP00000011877	ENSPPAP00000022955	Elongation factor for RNA polymerase II.	Integrator complex subunit 3.	0.449
ELL	INTS7	ENSPPAP00000011877	ENSPPAP00000041231	Elongation factor for RNA polymerase II.	Integrator complex subunit 7.	0.450
ELL	LARP7	ENSPPAP00000011877	ENSPPAP00000030954	Elongation factor for RNA polymerase II.	La ribonucleoprotein domain family member 7.	0.579
ELL	RPAP2	ENSPPAP00000011877	ENSPPAP00000024329	Elongation factor for RNA polymerase II.	RNA polymerase II associated protein 2.	0.407
ELL	ZC3H8	ENSPPAP00000011877	ENSPPAP00000009677	Elongation factor for RNA polymerase II.	Zinc finger CCCH-type containing 8.	0.837
ELL2	ELL	ENSPPAP00000004367	ENSPPAP00000011877	Elongation factor for RNA polymerase II 2.	Elongation factor for RNA polymerase II.	0.803
ELL2	ELL3	ENSPPAP00000004367	ENSPPAP00000007578	Elongation factor for RNA polymerase II 2.	Elongation factor for RNA polymerase II 3.	0.763