(20 nodes) rRNA catabolic process network (Pan paniscus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SLFN12	Schlafen family member 12. (579 aa)
	XRN1	5'-3' exoribonuclease 1. (1706 aa)
	ENSPPAP00000004436	Uncharacterized protein. (203 aa)
	DIS3L	DIS3 like exosome 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family. (1058 aa)
	TRIR	Telomerase RNA component interacting RNase. (172 aa)
	EXOSC5	Exosome component 5. (235 aa)
	SLFN12L	Schlafen family member 12 like. (617 aa)
	EXOSC8	Exosome component 8. (276 aa)
	ENSPPAP00000008094	Uncharacterized protein. (447 aa)
	EXOSC3	Exosome component 3. (275 aa)
	EXOSC2	Exosome component 2. (293 aa)
	EXOSC4	Exosome component 4. (245 aa)
	ERN2	Endoplasmic reticulum to nucleus signaling 2. (926 aa)
	ZCCHC7	Uncharacterized protein. (339 aa)
	EXOSC10	Exosome component 10. (890 aa)
	PELO	Protein pelota homolog; May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non- functional ribosomes and degrade damaged mRNAs. (385 aa)
	SLFN13	Schlafen family member 13. (897 aa)
	DIS3	DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family. (958 aa)
	EXOSC7	Exosome component 7. (291 aa)
	EXOSC9	Exosome component 9. (456 aa)

Your Current Organism:

Pan paniscus

NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DIS3	DIS3L	ENSPPAP00000038153	ENSPPAP00000004774	DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family.	DIS3 like exosome 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family.	0.685
DIS3	ENSPPAP00000004436	ENSPPAP00000038153	ENSPPAP00000004436	DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family.	Uncharacterized protein.	0.426
DIS3	ENSPPAP00000008094	ENSPPAP00000038153	ENSPPAP00000008094	DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family.	Uncharacterized protein.	0.426
DIS3	EXOSC10	ENSPPAP00000038153	ENSPPAP00000030845	DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family.	Exosome component 10.	0.999
DIS3	EXOSC2	ENSPPAP00000038153	ENSPPAP00000023252	DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family.	Exosome component 2.	0.999
DIS3	EXOSC3	ENSPPAP00000038153	ENSPPAP00000013434	DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family.	Exosome component 3.	0.999
DIS3	EXOSC4	ENSPPAP00000038153	ENSPPAP00000025237	DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family.	Exosome component 4.	0.999
DIS3	EXOSC5	ENSPPAP00000038153	ENSPPAP00000006047	DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family.	Exosome component 5.	0.999
DIS3	EXOSC7	ENSPPAP00000038153	ENSPPAP00000041919	DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family.	Exosome component 7.	0.999
DIS3	EXOSC8	ENSPPAP00000038153	ENSPPAP00000008070	DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family.	Exosome component 8.	0.999
DIS3	EXOSC9	ENSPPAP00000038153	ENSPPAP00000042613	DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family.	Exosome component 9.	0.999
DIS3	XRN1	ENSPPAP00000038153	ENSPPAP00000002379	DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family.	5'-3' exoribonuclease 1.	0.802
DIS3	ZCCHC7	ENSPPAP00000038153	ENSPPAP00000030612	DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family.	Uncharacterized protein.	0.426
DIS3L	DIS3	ENSPPAP00000004774	ENSPPAP00000038153	DIS3 like exosome 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family.	DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family.	0.685
DIS3L	EXOSC10	ENSPPAP00000004774	ENSPPAP00000030845	DIS3 like exosome 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family.	Exosome component 10.	0.999
DIS3L	EXOSC2	ENSPPAP00000004774	ENSPPAP00000023252	DIS3 like exosome 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family.	Exosome component 2.	0.998
DIS3L	EXOSC3	ENSPPAP00000004774	ENSPPAP00000013434	DIS3 like exosome 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family.	Exosome component 3.	0.998
DIS3L	EXOSC4	ENSPPAP00000004774	ENSPPAP00000025237	DIS3 like exosome 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family.	Exosome component 4.	0.998
DIS3L	EXOSC5	ENSPPAP00000004774	ENSPPAP00000006047	DIS3 like exosome 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family.	Exosome component 5.	0.997
DIS3L	EXOSC7	ENSPPAP00000004774	ENSPPAP00000041919	DIS3 like exosome 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family.	Exosome component 7.	0.998