STRINGSTRING
STXBP1 STXBP1 SNCA SNCA SNAP23 SNAP23 SYNJ1 SYNJ1 SNAP25 SNAP25 SV2A SV2A UNC13C UNC13C SNAP47 SNAP47 UNC13A UNC13A NAPA NAPA UNC13B UNC13B ERC2 ERC2 OTOF OTOF SNAP29 SNAP29
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
STXBP1Syntaxin binding protein 1; Belongs to the STXBP/unc-18/SEC1 family. (594 aa)
SNCAAlpha-synuclein; Neuronal protein that plays several roles in synaptic activity such as regulation of synaptic vesicle trafficking and subsequent neurotransmitter release. Participates as a monomer in synaptic vesicle exocytosis by enhancing vesicle priming, fusion and dilation of exocytotic fusion pores. Mechanistically, acts by increasing local Ca(2+) release from microdomains which is essential for the enhancement of ATP-induced exocytosis. Acts also as a molecular chaperone in its multimeric membrane-bound state, assisting in the folding of synaptic fusion components called SNAREs [...] (140 aa)
SNAP23Synaptosomal-associated protein; Belongs to the SNAP-25 family. (211 aa)
SYNJ1Synaptojanin 1. (1614 aa)
SNAP25Synaptosomal-associated protein; Belongs to the SNAP-25 family. (206 aa)
SV2ASynaptic vesicle glycoprotein 2A. (742 aa)
UNC13CC2 domain-containing protein. (135 aa)
SNAP47Synaptosome associated protein 47. (419 aa)
UNC13AUnc-13 homolog A. (1628 aa)
NAPANSF attachment protein alpha. (295 aa)
UNC13BUncharacterized protein. (4343 aa)
ERC2ELKS/RAB6-interacting/CAST family member 2. (957 aa)
OTOFOtoferlin. (1996 aa)
SNAP29Synaptosome associated protein 29. (318 aa)
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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