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| | PIK3C3 | Phosphatidylinositol 3-kinase catalytic subunit type 3. (916 aa) |
| | PINK1 | PTEN induced kinase 1. (554 aa) |
| | TCIRG1 | V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (830 aa) |
| | LOC100982674 | UBX domain-containing protein. (325 aa) |
| | PIK3R4 | Phosphoinositide-3-kinase regulatory subunit 4. (1358 aa) |
| | RAB1A | RAB1A, member RAS oncogene family. (202 aa) |
| | KIAA1324 | KIAA1324. (1013 aa) |
| | MAP1LC3B | Uncharacterized protein. (121 aa) |
| | IRGM | Immunity related GTPase M. (195 aa) |
| | CHMP6 | Uncharacterized protein. (224 aa) |
| | NBR1 | NBR1 autophagy cargo receptor. (988 aa) |
| | SRC | Tyrosine-protein kinase. (458 aa) |
| | PIP4K2B | Phosphatidylinositol-5-phosphate 4-kinase type 2 beta. (416 aa) |
| | VCP | Valosin containing protein; Belongs to the AAA ATPase family. (806 aa) |
| | EPM2A | Uncharacterized protein. (193 aa) |
| | ENSPPAP00000036510 | V-SNARE domain-containing protein. (192 aa) |
| | ENSPPAP00000036798 | Uncharacterized protein. (181 aa) |
| | STX12 | Syntaxin 12; Belongs to the syntaxin family. (276 aa) |
| | HDAC10 | Histone deacetylase 10. (669 aa) |
| | ENSPPAP00000037156 | Uncharacterized protein. (167 aa) |
| | ATG3 | Uncharacterized protein. (158 aa) |
| | RAB1B | RAB1B, member RAS oncogene family. (201 aa) |
| | TMEM41B | Transmembrane protein 41B. (290 aa) |
| | SNAP29 | Synaptosome associated protein 29. (318 aa) |
| | CHMP4C | Charged multivesicular body protein 4C. (233 aa) |
| | ATG16L2 | Autophagy related 16 like 2. (619 aa) |
| | WDR45 | WD repeat domain 45. (361 aa) |
| | HGS | Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] (777 aa) |
| | ATG13 | Autophagy-related protein 13; Belongs to the ATG13 family. Metazoan subfamily. (550 aa) |
| | MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2549 aa) |
| | VPS16 | Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family. (839 aa) |
| | MVB12A | Multivesicular body subunit 12A. (273 aa) |
| | HMOX1 | Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. (311 aa) |
| | ENSPPAP00000025927 | PX domain-containing protein. (445 aa) |
| | ATG9B | Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (826 aa) |
| | STX17 | Syntaxin 17; Belongs to the syntaxin family. (302 aa) |
| | TP53INP1 | Tumor protein p53 inducible nuclear protein 1. (240 aa) |
| | ATP13A2 | Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1195 aa) |
| | RETREG1 | Uncharacterized protein. (356 aa) |
| | ATG4B | Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (393 aa) |
| | MCOLN1 | Mucolipin 1. (580 aa) |
| | GABARAPL1 | Uncharacterized protein. (117 aa) |
| | VPS37A | VPS37A subunit of ESCRT-I. (397 aa) |
| | VPS39 | VPS39 subunit of HOPS complex. (886 aa) |
| | ATG9A | Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (848 aa) |
| | UBXN2B | Uncharacterized protein. (331 aa) |
| | SYNPO2 | Synaptopodin 2. (1260 aa) |
| | WIPI2 | WD repeat domain, phosphoinositide interacting 2. (454 aa) |
| | ENSPPAP00000023423 | Autophagy_N domain-containing protein. (120 aa) |
| | LIX1 | Limb and CNS expressed 1. (282 aa) |
| | LGALS8 | Galectin. (303 aa) |
| | ENSPPAP00000023303 | VPS37 C-terminal domain-containing protein. (367 aa) |
| | PRKN | E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (428 aa) |
| | ENSPPAP00000022845 | Uncharacterized protein. (126 aa) |
| | ULK3 | Unc-51 like kinase 3. (483 aa) |
| | AMBRA1 | Autophagy and beclin 1 regulator 1. (1298 aa) |
| | SQSTM1 | Sequestosome 1. (440 aa) |
| | UBXN6 | UBX domain protein 6. (441 aa) |
| | CHMP5 | Charged multivesicular body protein 5. (219 aa) |
| | PACS2 | Phosphofurin acidic cluster sorting protein 2. (899 aa) |
| | VPS25 | Vacuolar protein sorting 25 homolog. (176 aa) |
| | ENSPPAP00000021469 | Uncharacterized protein. (233 aa) |
| | YOD1 | YOD1 deubiquitinase. (301 aa) |
| | CHMP7 | Charged multivesicular body protein 7. (453 aa) |
| | ENSPPAP00000043045 | PIPK domain-containing protein. (255 aa) |
| | RIPK2 | Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (551 aa) |
| | ZFYVE1 | Zinc finger FYVE-type containing 1. (789 aa) |
| | ENSPPAP00000042332 | Uncharacterized protein. (349 aa) |
| | VPS28 | Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process. (221 aa) |
| | RAB33B | RAB33B, member RAS oncogene family. (229 aa) |
| | UFL1 | UFM1 specific ligase 1. (778 aa) |
| | AP4M1 | AP-4 complex subunit mu-1; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asym [...] (460 aa) |
| | ARL8B | ADP ribosylation factor like GTPase 8B; Belongs to the small GTPase superfamily. Arf family. (186 aa) |
| | ULK1 | Protein kinase domain-containing protein. (1408 aa) |
| | NOD2 | Nucleotide binding oligomerization domain containing 2. (1040 aa) |
| | MTMR14 | Myotubularin related protein 14. (650 aa) |
| | DDRGK1 | DDRGK domain containing 1. (314 aa) |
| | ENSPPAP00000021256 | Uncharacterized protein. (69 aa) |
| | VPS4B | Vacuolar protein sorting 4 homolog B; Belongs to the AAA ATPase family. (446 aa) |
| | TBC1D5 | TBC1 domain family member 5. (817 aa) |
| | STBD1 | Starch binding domain 1. (358 aa) |
| | ATG10 | Autophagy related 10. (220 aa) |
| | GABARAPL2 | GABA type A receptor associated protein like 2. (117 aa) |
| | VPS37C | VPS37C subunit of ESCRT-I. (355 aa) |
| | TSG101 | Tumor susceptibility 101. (390 aa) |
| | SNX30 | Sorting nexin family member 30. (437 aa) |
| | RAB19 | RAB19, member RAS oncogene family. (217 aa) |
| | VPS33A | Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family. (568 aa) |
| | ENSPPAP00000018201 | Uncharacterized protein. (201 aa) |
| | CHMP2B | Charged multivesicular body protein 2B. (213 aa) |
| | SMURF1 | E3 ubiquitin-protein ligase. (752 aa) |
| | ATG4D | Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (474 aa) |
| | ATG14 | Autophagy related 14. (492 aa) |
| | UFM1 | Ubiquitin-fold modifier 1; Ubiquitin-like modifier which can be covalently attached to substrate proteins as a monomer or a lysine-linked polymer in a post- translational process called ufmylation. Ufmylation on lysine residues of proteins may play a crucial role in a number of cellular processes. (103 aa) |
| | VMP1 | Vacuole membrane protein 1. (406 aa) |
| | STING1 | Stimulator of interferon protein. (379 aa) |
| | ENSPPAP00000016281 | Uncharacterized protein. (112 aa) |
| | CHMP1A | Charged multivesicular body protein 1A. (196 aa) |
| | LOC103785703 | Uncharacterized protein. (275 aa) |
| | VAMP8 | Vesicle associated membrane protein 8. (100 aa) |
| | SNX7 | Sorting nexin 7. (413 aa) |
| | RAB43 | RAB43, member RAS oncogene family. (212 aa) |
| | EPG5 | Ectopic P-granules autophagy protein 5 homolog. (2581 aa) |
| | MAP1LC3C | Microtubule associated protein 1 light chain 3 gamma. (147 aa) |
| | OGT | O-linked N-acetylglucosamine (GlcNAc) transferase. (1057 aa) |
| | PIK3C2B | Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta; Belongs to the PI3/PI4-kinase family. (1635 aa) |
| | SNF8 | Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family. (258 aa) |
| | GAA | Glucosidase alpha, acid; Belongs to the glycosyl hydrolase 31 family. (952 aa) |
| | RETREG3 | Reticulophagy regulator family member 3. (466 aa) |
| | LOC103784663 | Uncharacterized protein. (201 aa) |
| | LRBA | LPS responsive beige-like anchor protein. (2854 aa) |
| | BAG3 | BCL2 associated athanogene 3. (521 aa) |
| | ATP2A2 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1034 aa) |
| | TECPR1 | Tectonin beta-propeller repeat containing 1. (1165 aa) |
| | MTM1 | Myotubularin 1. (603 aa) |
| | TAZ | Tafazzin family protein; Some isoforms may be involved in cardiolipin metabolism. (292 aa) |
| | SNAPIN | SNARE-associated protein Snapin; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking and synaptic vesicle recycling; Belongs to t [...] (136 aa) |
| | VPS37B | VPS37B subunit of ESCRT-I. (285 aa) |
| | ARFIP2 | ADP ribosylation factor interacting protein 2. (341 aa) |
| | WDFY3 | WD repeat and FYVE domain containing 3. (3526 aa) |
| | TEX264 | Testis expressed 264, ER-phagy receptor. (313 aa) |
| | RB1CC1 | RB1 inducible coiled-coil 1. (1594 aa) |
| | VTI1B | Vesicle transport through interaction with t-SNAREs 1B. (232 aa) |
| | NSFL1C | NSFL1 cofactor. (372 aa) |
| | UBQLN1 | Ubiquilin 1. (589 aa) |
| | ATG7 | Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...] (704 aa) |
| | ENSPPAP00000035206 | Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. (156 aa) |
| | CHMP2A | Charged multivesicular body protein 2A. (222 aa) |
| | ATG5 | Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa) |
| | ILRUN | Inflammation and lipid regulator with UBA-like and NBR1-like domains. (298 aa) |
| | STAM | Signal transducing adaptor molecule. (540 aa) |
| | NPC1 | NPC intracellular cholesterol transporter 1. (1277 aa) |
| | BECN2 | Beclin 2. (431 aa) |
| | VPS36 | Vacuolar protein sorting 36 homolog. (328 aa) |
| | EMC6 | ER membrane protein complex subunit 6. (110 aa) |
| | RNF213 | Ring finger protein 213. (5256 aa) |
| | MFSD8 | Major facilitator superfamily domain containing 8. (521 aa) |
| | LOC100982471 | Uncharacterized protein; Belongs to the calmodulin family. (93 aa) |
| | RAB23 | RAB23, member RAS oncogene family. (237 aa) |
| | MAP1LC3B2 | Uncharacterized protein. (125 aa) |
| | UBQLN2 | Ubiquilin 2. (624 aa) |
| | ENSPPAP00000000334 | Uncharacterized protein. (197 aa) |
| | TP53INP2 | Tumor protein p53 inducible nuclear protein 2. (220 aa) |
| | RETREG2 | Reticulophagy regulator family member 2. (543 aa) |
| | WIPI1 | WD repeat domain, phosphoinositide interacting 1. (455 aa) |
| | ULK2 | Unc-51 like autophagy activating kinase 2. (1007 aa) |
| | ATG16L1 | Autophagy related 16 like 1. (624 aa) |
| | MAP1LC3A | Microtubule associated protein 1 light chain 3 alpha. (125 aa) |
| | ATG12 | Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. (181 aa) |
| | SPATA33 | Spermatogenesis associated 33. (140 aa) |
| | PHB2 | Prohibitin. (299 aa) |
| | ATG2B | Autophagy related 2B. (2073 aa) |
| | MTMR3 | Myotubularin related protein 3. (1199 aa) |
| | STAM2 | Signal transducing adaptor molecule 2. (525 aa) |
| | PJVK | Pejvakin. (352 aa) |
| | PGAM5 | Uncharacterized protein. (140 aa) |
| | CALCOCO2 | Calcium binding and coiled-coil domain 2. (467 aa) |
| | UBXN2A | UBX domain protein 2A. (259 aa) |
| | UFC1 | Ubiquitin-fold modifier-conjugating enzyme 1; E2-like enzyme which forms an intermediate with UFM1 via a thioester linkage. (167 aa) |
| | BECN1 | Beclin 1. (450 aa) |
| | MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (311 aa) |
| | PSEN1 | Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (467 aa) |
| | SPG11 | SPG11 vesicle trafficking associated, spatacsin. (2443 aa) |
| | ENSPPAP00000032146 | Uncharacterized protein. (79 aa) |
| | SNX14 | Sorting nexin 14. (946 aa) |
| | ENSPPAP00000032344 | Uncharacterized protein. (108 aa) |
| | LIX1L | Limb and CNS expressed 1 like. (337 aa) |
| | LOC100990173 | Uncharacterized protein. (172 aa) |
| | PLEKHM1 | Pleckstrin homology and RUN domain containing M1. (1061 aa) |
| | PLAA | Phospholipase A2 activating protein. (795 aa) |
| | VPS41 | Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family. (853 aa) |
| | EI24 | EI24 autophagy associated transmembrane protein. (350 aa) |
| | NOD1 | Nucleotide binding oligomerization domain containing 1. (953 aa) |
| | CHMP4B | Charged multivesicular body protein 4B. (219 aa) |
| | KLHL3 | Kelch like family member 3. (608 aa) |
| | MFN2 | Mitofusin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (757 aa) |
| | VTA1 | Vesicle trafficking 1. (307 aa) |
| | UBA5 | Ubiquitin like modifier activating enzyme 5. (404 aa) |
| | UVRAG | UV radiation resistance associated. (698 aa) |
| | ATG101 | Autophagy related 101. (218 aa) |
| | CHMP3 | Charged multivesicular body protein 3. (222 aa) |
| | ZFYVE26 | Zinc finger FYVE-type containing 26. (2530 aa) |
| | C5orf51 | Chromosome 5 open reading frame 51. (294 aa) |
| | VTI1A | Vesicle transport through interaction with t-SNAREs 1A. (185 aa) |
| | ATG2A | Autophagy related 2A. (1938 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (393 aa) |
| | RUBCNL | Rubicon like autophagy enhancer. (663 aa) |
| | RUFY4 | RUN and FYVE domain containing 4. (607 aa) |
| | LAMP2 | Lysosomal associated membrane protein 2. (411 aa) |
| | TIGAR | TP53 induced glycolysis regulatory phosphatase. (270 aa) |
| | USP30 | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (517 aa) |
| | WDR45B | Uncharacterized protein. (338 aa) |
| | WDR81 | WD repeat domain 81. (1941 aa) |
| | AUP1 | AUP1 lipid droplet regulating VLDL assembly factor. (394 aa) |
| | TRAPPC8 | Trafficking protein particle complex 8. (1420 aa) |
| | LOC100979126 | Uncharacterized protein; Belongs to the AAA ATPase family. (462 aa) |
| | GABARAP | GABA type A receptor-associated protein. (117 aa) |
