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| | KDM6A | Lysine demethylase 6A. (1453 aa) |
| | OGFOD1 | 2-oxoglutarate and iron dependent oxygenase domain containing 1. (542 aa) |
| | CYP4A22 | Cytochrome P450 family 4 subfamily A member 22; Belongs to the cytochrome P450 family. (519 aa) |
| | CYP27B1 | Cytochrome P450 family 27 subfamily B member 1; Belongs to the cytochrome P450 family. (508 aa) |
| | TET3 | Tet methylcytosine dioxygenase 3. (1795 aa) |
| | CYP26B1 | Cytochrome P450 family 26 subfamily B member 1; Belongs to the cytochrome P450 family. (495 aa) |
| | CYP2B6 | Cytochrome P450 family 2 subfamily B member 6; Belongs to the cytochrome P450 family. (491 aa) |
| | ENSPPAP00000018142 | Uncharacterized protein. (159 aa) |
| | AKR1C4 | Aldo-keto reductase family 1 member C4. (323 aa) |
| | MOXD1 | Monooxygenase DBH like 1. (544 aa) |
| | TYRP1 | Tyrosinase related protein 1. (537 aa) |
| | HR | HR lysine demethylase and nuclear receptor corepressor. (1189 aa) |
| | AKR1C1 | Aldo-keto reductase family 1 member C1. (295 aa) |
| | NOS2 | Nitric oxide synthase; Produces nitric oxide (NO). (1196 aa) |
| | RIOX2 | Bifunctional lysine-specific demethylase and histidyl-hydroxylase; Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. (452 aa) |
| | CYP4Z1 | Cytochrome P450 family 4 subfamily Z member 1; Belongs to the cytochrome P450 family. (505 aa) |
| | KDM6B | Lysine demethylase 6B. (1680 aa) |
| | TTI2 | TELO2 interacting protein 2. (508 aa) |
| | DEGS1 | Delta 4-desaturase, sphingolipid 1. (323 aa) |
| | EGLN2 | Egl-9 family hypoxia inducible factor 2. (407 aa) |
| | CYP2A7 | Cytochrome P450 family 2 subfamily A member 7; Belongs to the cytochrome P450 family. (453 aa) |
| | CYP17A1 | Uncharacterized protein; Belongs to the cytochrome P450 family. (350 aa) |
| | CYP11A1 | Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...] (521 aa) |
| | CYP26A1 | Cytochrome P450 family 26 subfamily A member 1; Belongs to the cytochrome P450 family. (428 aa) |
| | OGFOD3 | 2-oxoglutarate and iron dependent oxygenase domain containing 3. (331 aa) |
| | FMO3 | Dimethylaniline monooxygenase [N-oxide-forming]. (532 aa) |
| | TET2 | Tet methylcytosine dioxygenase 2. (2023 aa) |
| | ALKBH2 | AlkB homolog 2, alpha-ketoglutarate dependent dioxygenase. (261 aa) |
| | CYP4B1 | Cytochrome P450 family 4 subfamily B member 1; Belongs to the cytochrome P450 family. (512 aa) |
| | CCNDBP1 | Cyclin D1 binding protein 1. (360 aa) |
| | PHYHD1 | Phytanoyl-CoA dioxygenase domain containing 1. (297 aa) |
| | DEGS2 | Delta 4-desaturase, sphingolipid 2. (323 aa) |
| | CYP4X1 | Cytochrome P450 family 4 subfamily X member 1; Belongs to the cytochrome P450 family. (509 aa) |
| | CYP27C1 | Cytochrome P450 family 27 subfamily C member 1; Belongs to the cytochrome P450 family. (334 aa) |
| | PLOD1 | Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1. (737 aa) |
| | CYP2C19 | Cytochrome P450 family 2 subfamily C member 19; Belongs to the cytochrome P450 family. (490 aa) |
| | BBOX1 | Gamma-butyrobetaine hydroxylase 1. (387 aa) |
| | P4HTM | Prolyl 4-hydroxylase, transmembrane. (529 aa) |
| | KDM2B | Lysine demethylase 2B. (1336 aa) |
| | CMAH | Cytidine monophosphate-N-acetylneuraminic acid hydroxylase; Sialic acids are components of carbohydrate chains of glycoconjugates and are involved in cell-cell recognition and cell- pathogen interactions. Catalyzes the conversion of CMP-N- acetylneuraminic acid (CMP-Neu5Ac) into its hydroxylated derivative CMP-N-glycolylneuraminic acid (CMP-Neu5Gc), a sialic acid abundantly expressed at the surface of many cells. (613 aa) |
| | LOC103783188 | Aldo_ket_red domain-containing protein. (205 aa) |
| | FMO2 | Dimethylaniline monooxygenase [N-oxide-forming]. (535 aa) |
| | P4HB | Protein disulfide-isomerase. (513 aa) |
| | MICAL2 | Microtubule associated monooxygenase, calponin and LIM domain containing 2. (1124 aa) |
| | CYP1A1 | Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. (512 aa) |
| | CYP2E1 | Cytochrome P450 family 2 subfamily E member 1; Belongs to the cytochrome P450 family. (531 aa) |
| | CYP11B2 | Cytochrome P450 family 11 subfamily B member 2; Belongs to the cytochrome P450 family. (429 aa) |
| | COQ7 | 5-demethoxyubiquinone hydroxylase, mitochondrial; Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6- methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides. Involved in lifespan determination in a ubiquinone- independent manner. (217 aa) |
| | HIF1AN | Hypoxia inducible factor 1 subunit alpha inhibitor. (349 aa) |
| | SAAL1 | Serum amyloid A like 1. (474 aa) |
| | CYP46A1 | Cytochrome P450 family 46 subfamily A member 1; Belongs to the cytochrome P450 family. (500 aa) |
| | DBH | Dopamine beta-hydroxylase. (614 aa) |
| | HMOX1 | Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. (311 aa) |
| | KDM4B | Lysine demethylase 4B. (1130 aa) |
| | KDM7A | Lysine demethylase 7A. (876 aa) |
| | KDM5C | Lysine demethylase 5C. (1560 aa) |
| | CYP26C1 | Cytochrome P450 family 26 subfamily C member 1; Belongs to the cytochrome P450 family. (455 aa) |
| | ASPH | Aspartate beta-hydroxylase. (729 aa) |
| | KDM3A | JmjC domain-containing protein. (1032 aa) |
| | P3H3 | Prolyl 3-hydroxylase 3. (647 aa) |
| | LOC100994607 | Cytochrome P450 2D6; A cytochrome P450 monooxygenase involved in the metabolism of fatty acids, steroids and retinoids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the epoxidation of double bonds of polyunsaturated fatty acids (PUFA). Metabolizes endocannabinoid arachidonoylethanolamide (anandamide) to 20-hydroxyeicosatetraenoic acid ethanolamide (20-HETE-EA) and 8,9-, 11,12-, and 14,15-epoxyei [...] (501 aa) |
| | METTL26 | Uncharacterized protein. (127 aa) |
| | TH | Tyrosine hydroxylase. (528 aa) |
| | TET1 | Tet methylcytosine dioxygenase 1. (2134 aa) |
| | PCBD2 | Pterin-4 alpha-carbinolamine dehydratase 2. (128 aa) |
| | CYP8B1 | Cytochrome P450 family 8 subfamily B member 1; Belongs to the cytochrome P450 family. (496 aa) |
| | TMLHE | Uncharacterized protein. (332 aa) |
| | CYP39A1 | Cytochrome P450 family 39 subfamily A member 1; Belongs to the cytochrome P450 family. (471 aa) |
| | MSMO1 | Methylsterol monooxygenase 1; Belongs to the sterol desaturase family. (293 aa) |
| | CYP4F3 | Cytochrome P450 family 4 subfamily F member 3; Belongs to the cytochrome P450 family. (520 aa) |
| | POR | NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5; In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (680 aa) |
| | KDM2A | Lysine demethylase 2A. (1162 aa) |
| | MICAL3 | Microtubule associated monooxygenase, calponin and LIM domain containing 3. (1960 aa) |
| | COQ6 | Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6. (468 aa) |
| | FADS2 | Fatty acid desaturase 2. (444 aa) |
| | LOC100991744 | Uncharacterized protein. (506 aa) |
| | PHF2 | PHD finger protein 2. (1100 aa) |
| | PLOD3 | Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3. (738 aa) |
| | KDM3B | Lysine demethylase 3B. (1752 aa) |
| | PCBD1 | Pterin-4 alpha-carbinolamine dehydratase 1. (103 aa) |
| | CYP7B1 | Cytochrome P450 family 7 subfamily B member 1; Belongs to the cytochrome P450 family. (484 aa) |
| | CYP24A1 | Cytochrome P450 family 24 subfamily A member 1; Belongs to the cytochrome P450 family. (514 aa) |
| | KDM8 | Lysine demethylase 8. (454 aa) |
| | TPH1 | Tryptophan hydroxylase 1. (444 aa) |
| | CYP3A4 | Cytochrome P450 family 3 subfamily A member 4. (503 aa) |
| | CYP3A5 | Cytochrome P450 family 3 subfamily A member 5. (502 aa) |
| | NOS3 | Nitric oxide synthase 3. (997 aa) |
| | ENSPPAP00000032474 | Uncharacterized protein; Belongs to the cytochrome P450 family. (481 aa) |
| | FAXDC2 | Fatty acid hydroxylase domain containing 2; Belongs to the sterol desaturase family. (310 aa) |
| | PLOD2 | Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2. (758 aa) |
| | KDM4A | Uncharacterized protein. (1064 aa) |
| | CRTAP | Cartilage associated protein. (343 aa) |
| | LOC100968405 | Flavin-containing monooxygenase. (484 aa) |
| | LOC100983851 | Uncharacterized protein; Belongs to the cytochrome P450 family. (494 aa) |
| | P3H2 | Prolyl 3-hydroxylase 2. (636 aa) |
| | CYP4F22 | Cytochrome P450 family 4 subfamily F member 22; Belongs to the cytochrome P450 family. (531 aa) |
| | CYP4A11 | Cytochrome P450 family 4 subfamily A member 11; Belongs to the cytochrome P450 family. (518 aa) |
| | MICAL1 | Microtubule associated monooxygenase, calponin and LIM domain containing 1. (1086 aa) |
| | LOC100967379 | Uncharacterized protein. (393 aa) |
| | CYP20A1 | Cytochrome P450 family 20 subfamily A member 1. (472 aa) |
| | CYP51A1 | Cytochrome P450 family 51 subfamily A member 1; Belongs to the cytochrome P450 family. (509 aa) |
| | KDM5A | Lysine demethylase 5A. (1643 aa) |
| | LOC100984524 | Uncharacterized protein. (372 aa) |
| | CYP2J2 | Cytochrome P450 family 2 subfamily J member 2; Belongs to the cytochrome P450 family. (502 aa) |
| | P3H1 | Prolyl 3-hydroxylase 1. (797 aa) |
| | KDM5B | Lysine demethylase 5B. (1580 aa) |
| | KDM1B | Uncharacterized protein. (822 aa) |
| | ALKBH1 | AlkB homolog 1, histone H2A dioxygenase. (389 aa) |
| | JMJD4 | Jumonji domain containing 4. (463 aa) |
| | P4HA3 | Prolyl 4-hydroxylase subunit alpha 3. (543 aa) |
| | KDM1A | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (876 aa) |
| | PTGIS | Prostacyclin synthase; Catalyzes the isomerization of prostaglandin H2 to prostacyclin (= prostaglandin I2); Belongs to the cytochrome P450 family. (501 aa) |
| | PHYH | Phytanoyl-CoA 2-hydroxylase. (338 aa) |
| | CYP27A1 | Cytochrome P450 family 27 subfamily A member 1; Belongs to the cytochrome P450 family. (531 aa) |
| | KLKB1 | Kallikrein B1; Belongs to the peptidase S1 family. (638 aa) |
| | LOC100996034 | Uncharacterized protein; Belongs to the cytochrome P450 family. (431 aa) |
| | KDM4C | Lysine demethylase 4C. (1056 aa) |
| | FMO1 | Dimethylaniline monooxygenase [N-oxide-forming]. (532 aa) |
| | PIGS | Phosphatidylinositol glycan anchor biosynthesis class S. (555 aa) |
| | CYP2R1 | Cytochrome P450 family 2 subfamily R member 1; Belongs to the cytochrome P450 family. (501 aa) |
| | FADS1 | Fatty acid desaturase 1. (501 aa) |
| | AGMO | Alkylglycerol monooxygenase; Belongs to the sterol desaturase family. (456 aa) |
| | PTGS2 | Prostaglandin-endoperoxide synthase 2. (604 aa) |
| | CYP2U1 | Cytochrome P450 family 2 subfamily U member 1; Belongs to the cytochrome P450 family. (596 aa) |
| | ENSPPAP00000041730 | Uncharacterized protein. (97 aa) |
| | CYP7A1 | Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family. (504 aa) |
| | ENSPPAP00000042309 | Uncharacterized protein. (514 aa) |
| | LOC100989599 | Uncharacterized protein; Belongs to the cytochrome P450 family. (339 aa) |
| | NOS1 | Nitric oxide synthase; Produces nitric oxide (NO). (1403 aa) |
| | SC5D | Sterol-C5-desaturase; Belongs to the sterol desaturase family. (299 aa) |
| | AKR1D1 | Aldo-keto reductase family 1 member D1. (326 aa) |
| | SQLE | Squalene epoxidase. (573 aa) |
| | OGFOD2 | 2-oxoglutarate and iron dependent oxygenase domain containing 2. (350 aa) |
| | DOHH | Deoxyhypusine hydroxylase; Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L- lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor; Belongs to the deoxyhypusine hydroxylase family. (289 aa) |
| | LOC100967578 | Uncharacterized protein. (415 aa) |
| | CYP2A13 | Cytochrome P450 family 2 subfamily A member 13; Belongs to the cytochrome P450 family. (494 aa) |
| | CYP11B1 | Cytochrome P450 family 11 subfamily B member 1; Belongs to the cytochrome P450 family. (500 aa) |
| | PAH | Phenylalanine hydroxylase. (452 aa) |
| | ALKBH4 | AlkB homolog 4, lysine demethylase. (302 aa) |
| | ALKBH8 | AlkB homolog 8, tRNA methyltransferase. (664 aa) |
| | HSPBAP1 | HSPB1 associated protein 1. (518 aa) |
| | CYP4F11 | Cytochrome P450 family 4 subfamily F member 11; Belongs to the cytochrome P450 family. (524 aa) |
| | NLRP11 | NLR family pyrin domain containing 11. (1033 aa) |
| | EGLN3 | Egl-9 family hypoxia inducible factor 3. (239 aa) |
| | ENSPPAP00000004707 | Uncharacterized protein; Belongs to the fatty acid desaturase type 1 family. (346 aa) |
| | RIOX1 | Bifunctional lysine-specific demethylase and histidyl-hydroxylase; Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. (565 aa) |
| | FMO4 | Dimethylaniline monooxygenase [N-oxide-forming]. (558 aa) |
| | TMC7 | Transmembrane channel-like protein. (715 aa) |
| | KDM4E | Lysine demethylase 4E. (506 aa) |
| | LOC100988273 | Uncharacterized protein. (289 aa) |
| | CYP3A43 | Cytochrome P450 family 3 subfamily A member 43. (504 aa) |
| | CH25H | Cholesterol 25-hydroxylase; Belongs to the sterol desaturase family. (272 aa) |
| | CYP4F2 | Cytochrome P450 family 4 subfamily F member 2; Belongs to the cytochrome P450 family. (520 aa) |
| | ENSPPAP00000007031 | Uncharacterized protein. (104 aa) |
| | SCD5 | Stearoyl-CoA desaturase 5; Belongs to the fatty acid desaturase type 1 family. (330 aa) |
| | CYP4V2 | Cytochrome P450 family 4 subfamily V member 2; Belongs to the cytochrome P450 family. (525 aa) |
| | TYW5 | tRNA-yW synthesizing protein 5. (315 aa) |
| | LOC100981320 | Uncharacterized protein. (231 aa) |
| | PTGS1 | Prostaglandin-endoperoxide synthase 1. (599 aa) |
| | FADS3 | Fatty acid desaturase 3. (449 aa) |
| | LOC100974522 | Uncharacterized protein; Belongs to the cytochrome P450 family. (343 aa) |
| | ENSPPAP00000009371 | Uncharacterized protein; Belongs to the cytochrome P450 family. (470 aa) |
| | CYP1A2 | Cytochrome P450 family 1 subfamily A member 2; Belongs to the cytochrome P450 family. (517 aa) |
| | FTO | FTO alpha-ketoglutarate dependent dioxygenase. (559 aa) |
| | MICALCL | BMERB domain-containing protein. (689 aa) |
| | CYP4F8 | Cytochrome P450 family 4 subfamily F member 8; Belongs to the cytochrome P450 family. (520 aa) |
| | TBXAS1 | Thromboxane A synthase 1; Belongs to the cytochrome P450 family. (579 aa) |
| | HMOX2 | Heme oxygenase 2. (370 aa) |
| | CYP4F12 | Cytochrome P450 family 4 subfamily F member 12; Belongs to the cytochrome P450 family. (524 aa) |
| | AKR1C3 | Aldo-keto reductase family 1 member C3. (323 aa) |
| | JMJD6 | Jumonji domain containing 6, arginine demethylase and lysine hydroxylase. (420 aa) |
| | RSBN1 | Round spermatid basic protein 1. (802 aa) |
| | TMEM189 | Transmembrane protein 189. (270 aa) |
| | ALKBH3 | AlkB homolog 3, alpha-ketoglutaratedependent dioxygenase. (286 aa) |
| | PHF8 | PHD finger protein 8. (1060 aa) |
| | UBE2V1 | Ubiquitin conjugating enzyme E2 V1. (170 aa) |
| | P4HA2 | Prolyl 4-hydroxylase subunit alpha 2. (535 aa) |
| | TYR | Tyrosinase. (529 aa) |
| | LOC100990887 | Flavin-containing monooxygenase. (484 aa) |
| | PAM | Peptidylglycine alpha-amidating monooxygenase. (974 aa) |
| | CYP19A1 | Cytochrome P450 family 19 subfamily A member 1; Belongs to the cytochrome P450 family. (503 aa) |
| | SCD | Stearoyl-CoA desaturase; Belongs to the fatty acid desaturase type 1 family. (359 aa) |
| | EGLN1 | Fe2OG dioxygenase domain-containing protein. (341 aa) |
| | FADS6 | Fatty acid desaturase 6. (338 aa) |
| | P4HA1 | Prolyl 4-hydroxylase subunit alpha 1. (527 aa) |
| | JMJD8 | Jumonji domain containing 8. (270 aa) |
| | CYP2S1 | Cytochrome P450 family 2 subfamily S member 1; Belongs to the cytochrome P450 family. (504 aa) |
| | ALKBH5 | AlkB homolog 5, RNA demethylase. (394 aa) |
| | TPH2 | Tryptophan hydroxylase 2. (490 aa) |
| | LOC100975985 | Uncharacterized protein. (503 aa) |
| | FMO5 | Dimethylaniline monooxygenase [N-oxide-forming]. (533 aa) |
| | KMO | Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid, a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development. Quinolinic acid may also affect NMDA receptor signaling in pancreatic beta cells, osteoblasts, myocardial cells, and the gastrointestinal tract. (492 aa) |
