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BCAS3 BCAS3 ENSPPAP00000014996 ENSPPAP00000014996 ENSPPAP00000014920 ENSPPAP00000014920 PARK7 PARK7 TCF7L2 TCF7L2 PPID PPID TAF7L TAF7L GTF2H1 GTF2H1 MED16 MED16 DCAF13 DCAF13 SRARP SRARP PAGR1 PAGR1 PPARG PPARG RARG RARG THRAP3 THRAP3 NR1I2 NR1I2 GAS2L1 GAS2L1 HIF1A HIF1A NRBF2 NRBF2 LOC100985819 LOC100985819 MED25 MED25 ENSPPAP00000009926 ENSPPAP00000009926 XBP1 XBP1 ASXL1 ASXL1 DAXX DAXX ENSPPAP00000009290 ENSPPAP00000009290 RNF14 RNF14 ENSPPAP00000008914 ENSPPAP00000008914 PRAME PRAME NKX3-1 NKX3-1 DCAF1 DCAF1 NR1H2 NR1H2 NR1H4 NR1H4 SIRT1 SIRT1 LOC100986655 LOC100986655 ESR1 ESR1 ENSPPAP00000006767 ENSPPAP00000006767 NR0B1 NR0B1 LCOR LCOR LOC100992554 LOC100992554 ENSPPAP00000005982 ENSPPAP00000005982 TACC1 TACC1 FOXH1 FOXH1 CNOT1 CNOT1 TRIP4 TRIP4 TRIM24 TRIM24 FLT3 FLT3 ENSPPAP00000003540 ENSPPAP00000003540 DNAAF4 DNAAF4 CRY1 CRY1 NSD1 NSD1 TAF1 TAF1 PRPF6 PRPF6 FKBP4 FKBP4 NRIP1 NRIP1 CALR CALR RERG RERG BAZ2A BAZ2A WBP2 WBP2 ENSPPAP00000023305 ENSPPAP00000023305 ENSPPAP00000023741 ENSPPAP00000023741 PRMT2 PRMT2 GRIP1 GRIP1 PPARGC1B PPARGC1B ARID1A ARID1A PROX1 PROX1 YWHAH YWHAH NR4A1 NR4A1 CTNNB1 CTNNB1 RNF6 RNF6 OASL OASL TRIM68 TRIM68 LATS1 LATS1 SLC30A9 SLC30A9 ARID5A ARID5A MYOD1 MYOD1 TAF10 TAF10 TGFB1I1 TGFB1I1 KDM3A KDM3A PHB2 PHB2 VDR VDR SMARCE1 SMARCE1 CRX CRX C1D C1D MED4 MED4 TACC2 TACC2 FOXP1 FOXP1 SMARCD3 SMARCD3 PKN1 PKN1 NR0B2 NR0B2 ENSPPAP00000033419 ENSPPAP00000033419 STAT1 STAT1 STAT5B STAT5B NCOA7 NCOA7 LRIF1 LRIF1 LOC100993364 LOC100993364 GTF2B GTF2B ENSPPAP00000034872 ENSPPAP00000034872 PADI2 PADI2 MED1 MED1 NCOR2 NCOR2 ACTN4 ACTN4 SRC SRC BUD31 BUD31 PARP1 PARP1 SNW1 SNW1 ZBTB7A ZBTB7A ENSPPAP00000036589 ENSPPAP00000036589 ENSPPAP00000036860 ENSPPAP00000036860 TAF11 TAF11 NR4A3 NR4A3 HMGN3 HMGN3 DDX5 DDX5 KDM1A KDM1A RXRA RXRA DDX54 DDX54 ZNF366 ZNF366 NCOA1 NCOA1 WIPI1 WIPI1 KDM4C KDM4C TMF1 TMF1 TADA3 TADA3 TRIP12 TRIP12 LEF1 LEF1 JMJD1C JMJD1C TCF21 TCF21 SMARCA4 SMARCA4 ENSPPAP00000042767 ENSPPAP00000042767 MMS19 MMS19 MED14 MED14 PPARGC1A PPARGC1A LOC100989848 LOC100989848 PRKCB PRKCB MED30 MED30 ISL1 ISL1 SMAD3 SMAD3 CRY2 CRY2 STRN STRN MED13 MED13 PCNA PCNA NCOA3 NCOA3 CTBP2 CTBP2 ENSPPAP00000019394 ENSPPAP00000019394 ENSPPAP00000019279 ENSPPAP00000019279 EP300 EP300 MED12 MED12 ENSPPAP00000018968 ENSPPAP00000018968 TRERF1 TRERF1 ENSPPAP00000018781 ENSPPAP00000018781 BRD8 BRD8 CCDC62 CCDC62 MED24 MED24 NR4A2 NR4A2 TRIP6 TRIP6 ENSPPAP00000017043 ENSPPAP00000017043 NCOA2 NCOA2 ENSPPAP00000016019 ENSPPAP00000016019 HMGA1 HMGA1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
BCAS3BCAS3 microtubule associated cell migration factor. (950 aa)
ENSPPAP00000014996Uncharacterized protein. (108 aa)
ENSPPAP00000014920Uncharacterized protein. (290 aa)
PARK7Parkinsonism associated deglycase. (189 aa)
TCF7L2Transcription factor 7 like 2. (555 aa)
PPIDPeptidylprolyl isomerase D. (370 aa)
TAF7LTATA-box binding protein associated factor 7 like. (457 aa)
GTF2H1General transcription factor IIH subunit 1. (548 aa)
MED16Mediator of RNA polymerase II transcription subunit 16; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (837 aa)
DCAF13DDB1 and CUL4 associated factor 13. (597 aa)
SRARPSteroid receptor associated and regulated protein. (169 aa)
PAGR1PAXIP1 associated glutamate rich protein 1. (254 aa)
PPARGPeroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (505 aa)
RARGRetinoic acid receptor gamma. (464 aa)
THRAP3Thyroid hormone receptor associated protein 3. (954 aa)
NR1I2Nuclear receptor subfamily 1 group I member 2. (473 aa)
GAS2L1Growth arrest specific 2 like 1. (681 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (850 aa)
NRBF2Uncharacterized protein. (288 aa)
LOC100985819Uncharacterized protein. (377 aa)
MED25Mediator complex subunit 25. (747 aa)
ENSPPAP00000009926EF-hand domain-containing protein. (85 aa)
XBP1BZIP domain-containing protein. (380 aa)
ASXL1ASXL transcriptional regulator 1. (1536 aa)
DAXXDeath domain associated protein. (748 aa)
ENSPPAP00000009290Uncharacterized protein. (354 aa)
RNF14RBR-type E3 ubiquitin transferase. (474 aa)
ENSPPAP00000008914Uncharacterized protein. (164 aa)
PRAMEPreferentially expressed antigen in melanoma. (509 aa)
NKX3-1NK3 homeobox 1. (223 aa)
DCAF1DDB1 and CUL4 associated factor 1. (1507 aa)
NR1H2Nuclear receptor subfamily 1 group H member 2. (461 aa)
NR1H4Nuclear receptor subfamily 1 group H member 4. (482 aa)
SIRT1Sirtuin 1. (693 aa)
LOC100986655GPS2_interact domain-containing protein. (211 aa)
ESR1Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (595 aa)
ENSPPAP00000006767Uncharacterized protein. (240 aa)
NR0B1Nuclear receptor subfamily 0 group B member 1. (470 aa)
LCORLigand dependent nuclear receptor corepressor. (1556 aa)
LOC100992554Nuclear receptor corepressor 1. (2259 aa)
ENSPPAP00000005982Uncharacterized protein. (84 aa)
TACC1Transforming acidic coiled-coil containing protein 1. (806 aa)
FOXH1Fork-head domain-containing protein. (452 aa)
CNOT1CCR4-NOT transcription complex subunit 1. (2383 aa)
TRIP4Thyroid hormone receptor interactor 4. (581 aa)
TRIM24Tripartite motif containing 24. (1050 aa)
FLT3Fms related tyrosine kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (978 aa)
ENSPPAP00000003540Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (246 aa)
DNAAF4Dynein assembly factor 4, axonemal; Involved in neuronal migration during development of the cerebral neocortex. May regulate the stability and proteasomal degradation of the estrogen receptors that play an important role in neuronal differentiation, survival and plasticity. Axonemal dynein assembly factor required for ciliary motility (By similarity). (420 aa)
CRY1Cryptochrome circadian regulator 1. (586 aa)
NSD1Nuclear receptor binding SET domain protein 1. (2697 aa)
TAF1Transcription initiation factor TFIID subunit. (1916 aa)
PRPF6Pre-mRNA processing factor 6. (941 aa)
FKBP4Peptidylprolyl isomerase. (456 aa)
NRIP1Nuclear receptor interacting protein 1. (1158 aa)
CALRCalreticulin. (417 aa)
RERGRAS like estrogen regulated growth inhibitor. (199 aa)
BAZ2ABromodomain adjacent to zinc finger domain 2A. (1906 aa)
WBP2WW domain binding protein 2. (261 aa)
ENSPPAP00000023305DJ-1_PfpI domain-containing protein. (168 aa)
ENSPPAP00000023741Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (400 aa)
PRMT2Protein arginine methyltransferase 2; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (433 aa)
GRIP1Glutamate receptor interacting protein 1. (1204 aa)
PPARGC1BPPARG coactivator 1 beta. (997 aa)
ARID1AAT-rich interaction domain 1A. (2150 aa)
PROX1Prospero homeobox 1. (737 aa)
YWHAHTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta; Belongs to the 14-3-3 family. (243 aa)
NR4A1Nuclear receptor subfamily 4 group A member 1. (652 aa)
CTNNB1Catenin beta 1. (781 aa)
RNF6Ring finger protein 6. (685 aa)
OASL2'-5'-oligoadenylate synthetase like. (514 aa)
TRIM68Tripartite motif containing 68. (485 aa)
LATS1Large tumor suppressor kinase 1. (1130 aa)
SLC30A9Solute carrier family 30 member 9. (567 aa)
ARID5AAT-rich interaction domain 5A. (593 aa)
MYOD1Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (320 aa)
TAF10Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (186 aa)
TGFB1I1Transforming growth factor beta-1-induced transcript 1 protein; Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways. (470 aa)
KDM3AJmjC domain-containing protein. (1032 aa)
PHB2Prohibitin. (299 aa)
VDRVitamin D receptor. (477 aa)
SMARCE1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1. (411 aa)
CRXHomeobox domain-containing protein. (282 aa)
C1DUncharacterized protein. (180 aa)
MED4Mediator of RNA polymerase II transcription subunit 4; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (270 aa)
TACC2Transforming acidic coiled-coil containing protein 2. (2931 aa)
FOXP1Forkhead box P1. (676 aa)
SMARCD3SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3. (430 aa)
PKN1Protein kinase N1. (948 aa)
NR0B2Nuclear receptor subfamily 0 group B member 2. (257 aa)
ENSPPAP00000033419RBR-type E3 ubiquitin transferase. (362 aa)
STAT1Signal transducer and activator of transcription. (759 aa)
STAT5BSignal transducer and activator of transcription. (789 aa)
NCOA7Nuclear receptor coactivator 7. (917 aa)
LRIF1Ligand dependent nuclear receptor interacting factor 1. (769 aa)
LOC100993364Uncharacterized protein. (106 aa)
GTF2BGeneral transcription factor IIB. (348 aa)
ENSPPAP00000034872Uncharacterized protein. (67 aa)
PADI2Peptidyl arginine deiminase 2. (665 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1555 aa)
NCOR2Nuclear receptor corepressor 2. (2510 aa)
ACTN4Actinin alpha 4. (931 aa)
SRCTyrosine-protein kinase. (458 aa)
BUD31BUD31 homolog. (144 aa)
PARP1Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1014 aa)
SNW1SNW domain containing 1. (571 aa)
ZBTB7AUncharacterized protein. (509 aa)
ENSPPAP00000036589Peptidylprolyl isomerase. (439 aa)
ENSPPAP00000036860Uncharacterized protein. (189 aa)
TAF11TATA-box binding protein associated factor 11. (211 aa)
NR4A3Nuclear receptor domain-containing protein. (359 aa)
HMGN3Uncharacterized protein. (104 aa)
DDX5DEAD-box helicase 5; Belongs to the DEAD box helicase family. (614 aa)
KDM1ALysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (876 aa)
RXRARetinoid X receptor alpha. (472 aa)
DDX54ATP-dependent RNA helicase DDX54; Belongs to the DEAD box helicase family. DDX54/DBP10 subfamily. (885 aa)
ZNF366Zinc finger protein 366. (744 aa)
NCOA1Nuclear receptor coactivator. (1441 aa)
WIPI1WD repeat domain, phosphoinositide interacting 1. (455 aa)
KDM4CLysine demethylase 4C. (1056 aa)
TMF1TATA element modulatory factor 1. (1096 aa)
TADA3Transcriptional adaptor 3. (432 aa)
TRIP12Thyroid hormone receptor interactor 12. (2068 aa)
LEF1Lymphoid enhancer binding factor 1. (399 aa)
JMJD1CJumonji domain containing 1C. (2540 aa)
TCF21Transcription factor 21. (179 aa)
SMARCA4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4. (1679 aa)
ENSPPAP00000042767SKIP_SNW domain-containing protein. (390 aa)
MMS19MMS19 homolog, cytosolic iron-sulfur assembly component. (1030 aa)
MED14Mediator of RNA polymerase II transcription subunit 14; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1466 aa)
PPARGC1APPARG coactivator 1 alpha. (809 aa)
LOC100989848Uncharacterized protein. (251 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (615 aa)
MED30Mediator complex subunit 30. (178 aa)
ISL1ISL LIM homeobox 1. (349 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
CRY2Cryptochrome circadian regulator 2. (614 aa)
STRNStriatin. (627 aa)
MED13Mediator of RNA polymerase II transcription subunit 13; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (2173 aa)
PCNAProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
NCOA3Nuclear receptor coactivator. (1423 aa)
CTBP2C-terminal binding protein 2. (985 aa)
ENSPPAP00000019394HMG box domain-containing protein. (174 aa)
ENSPPAP00000019279Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (467 aa)
EP300E1A binding protein p300. (2411 aa)
MED12Mediator complex subunit 12. (2182 aa)
ENSPPAP00000018968Uncharacterized protein. (239 aa)
TRERF1Transcriptional regulating factor 1. (1208 aa)
ENSPPAP00000018781Uncharacterized protein. (136 aa)
BRD8Bromodomain containing 8. (1235 aa)
CCDC62Coiled-coil domain containing 62. (669 aa)
MED24Mediator complex subunit 24. (1008 aa)
NR4A2Nuclear receptor subfamily 4 group A member 2. (598 aa)
TRIP6Thyroid hormone receptor interactor 6. (476 aa)
ENSPPAP00000017043Peptidylprolyl isomerase. (371 aa)
NCOA2Nuclear receptor coactivator. (1464 aa)
ENSPPAP00000016019Uncharacterized protein. (144 aa)
HMGA1Uncharacterized protein. (201 aa)
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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