(82 nodes) GDP binding network (Pan paniscus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSPPAP00000021549	Uncharacterized protein. (160 aa)
	RIT1	Ras like without CAAX 1. (236 aa)
	RRAS2	Uncharacterized protein. (169 aa)
	RASEF	RAS and EF-hand domain containing. (740 aa)
	RAB5A	RAB5A, member RAS oncogene family. (216 aa)
	ARL2	ADP ribosylation factor like GTPase 2; Belongs to the small GTPase superfamily. Arf family. (184 aa)
	ENSPPAP00000037876	GB1/RHD3-type G domain-containing protein. (492 aa)
	RAB17	RAB17, member RAS oncogene family. (211 aa)
	RAB18	RAB18, member RAS oncogene family. (206 aa)
	ENSPPAP00000037156	Uncharacterized protein. (167 aa)
	RAB8A	RAB8A, member RAS oncogene family. (207 aa)
	ENSPPAP00000035001	Uncharacterized protein. (110 aa)
	RAP1A	RAP1A, member of RAS oncogene family. (184 aa)
	RAP1B	RAP1B, member of RAS oncogene family. (184 aa)
	RAB27B	RAB27B, member RAS oncogene family. (218 aa)
	KRAS	KRAS proto-oncogene, GTPase. (189 aa)
	GNAI3	G protein subunit alpha i3. (354 aa)
	RAP2C	RAP2C, member of RAS oncogene family. (183 aa)
	NRAS	NRAS proto-oncogene, GTPase. (189 aa)
	RAB8B	RAB8B, member RAS oncogene family. (207 aa)
	RAB4A	RAB4A, member RAS oncogene family. (218 aa)
	DYNC1LI1	Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (523 aa)
	MRAS	Muscle RAS oncogene homolog. (208 aa)
	ENSPPAP00000025599	Uncharacterized protein. (195 aa)
	RALB	RAS like proto-oncogene B. (254 aa)
	RAB5B	RAB5B, member RAS oncogene family. (223 aa)
	ENSPPAP00000024234	Uncharacterized protein. (152 aa)
	TMEM19	Uncharacterized protein. (430 aa)
	ARL3	ADP ribosylation factor like GTPase 3; Belongs to the small GTPase superfamily. Arf family. (182 aa)
	PRPS2	Phosphoribosyl pyrophosphate synthetase 2. (321 aa)
	GNAT1	G protein subunit alpha transducin 1. (350 aa)
	RHEBL1	RHEB like 1. (183 aa)
	RIT2	Ras like without CAAX 2. (217 aa)
	ARL8B	ADP ribosylation factor like GTPase 8B; Belongs to the small GTPase superfamily. Arf family. (186 aa)
	SEPTIN12	Septin 12; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (358 aa)
	RRAS	RAS related. (176 aa)
	ARF6	Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (175 aa)
	LOC100974009	Uncharacterized protein. (184 aa)
	RAB14	RAB14, member RAS oncogene family. (212 aa)
	RAB10	RAB10, member RAS oncogene family. (200 aa)
	RASL12	RAS like family 12. (266 aa)
	RAN	GTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family. (233 aa)
	RAB2A	RAB2A, member RAS oncogene family. (208 aa)
	RAB22A	RAB22A, member RAS oncogene family. (194 aa)
	RAB27A	RAB27A, member RAS oncogene family. (221 aa)
	ENSPPAP00000014681	Uncharacterized protein. (174 aa)
	GNAI1	G protein subunit alpha i1. (323 aa)
	RRAGC	Ras related GTP binding C. (399 aa)
	RRAGD	Ras related GTP binding D. (400 aa)
	HRAS	HRas proto-oncogene, GTPase. (189 aa)
	RAB11B	Uncharacterized protein. (221 aa)
	ENSPPAP00000010638	Uncharacterized protein. (172 aa)
	ENSPPAP00000010591	Uncharacterized protein. (186 aa)
	UCP1	Uncoupling protein 1; Belongs to the mitochondrial carrier (TC 2.A.29) family. (307 aa)
	RHEB	Uncharacterized protein. (173 aa)
	TRIM23	Tripartite motif containing 23. (574 aa)
	RAB35	Uncharacterized protein. (348 aa)
	RAP2B	RAP2B, member of RAS oncogene family. (183 aa)
	ERAS	ES cell expressed Ras. (233 aa)
	DIRAS3	DIRAS family GTPase 3. (229 aa)
	ENSPPAP00000006260	Uncharacterized protein. (99 aa)
	RAB9A	RAB9A, member RAS oncogene family. (201 aa)
	GEM	GTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (295 aa)
	RAB31	RAB31, member RAS oncogene family. (183 aa)
	RHOB	Ras homolog family member B. (196 aa)
	RAP2A	RAP2A, member of RAS oncogene family. (183 aa)
	ENSPPAP00000005542	Uncharacterized protein. (133 aa)
	DIRAS2	DIRAS family GTPase 2. (199 aa)
	SRP54	Signal recognition particle 54 kDa protein; Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein). Belongs to the GTP-binding SRP family. SRP54 subfamily. (504 aa)
	RAB29	RAB29, member RAS oncogene family. (203 aa)
	RAN-2	GTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family. (217 aa)
	RAB12	RAB12, member RAS oncogene family. (212 aa)
	MIEF1	Mitochondrial elongation factor 1. (478 aa)
	RERG	RAS like estrogen regulated growth inhibitor. (199 aa)
	RALA	RAS like proto-oncogene A. (206 aa)
	DIRAS1	DIRAS family GTPase 1. (198 aa)
	RAB9B	RAB9B, member RAS oncogene family. (201 aa)
	RAB3B	RAB3B, member RAS oncogene family. (228 aa)
	RAB42	RAB42, member RAS oncogene family. (218 aa)
	RAB28	RAB28, member RAS oncogene family. (221 aa)
	RAB21	RAB21, member RAS oncogene family. (224 aa)
	ENSPPAP00000041709	Uncharacterized protein. (199 aa)

Your Current Organism:

Pan paniscus

NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARF6	RAB28	ENSPPAP00000020137	ENSPPAP00000042246	Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family.	RAB28, member RAS oncogene family.	0.441
ARF6	RAB35	ENSPPAP00000020137	ENSPPAP00000008415	Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family.	Uncharacterized protein.	0.400
ARF6	RAB4A	ENSPPAP00000020137	ENSPPAP00000027074	Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family.	RAB4A, member RAS oncogene family.	0.545
ARL2	HRAS	ENSPPAP00000037929	ENSPPAP00000010823	ADP ribosylation factor like GTPase 2; Belongs to the small GTPase superfamily. Arf family.	HRas proto-oncogene, GTPase.	0.564
ARL2	KRAS	ENSPPAP00000037929	ENSPPAP00000030946	ADP ribosylation factor like GTPase 2; Belongs to the small GTPase superfamily. Arf family.	KRAS proto-oncogene, GTPase.	0.426
ARL2	LOC100974009	ENSPPAP00000037929	ENSPPAP00000017517	ADP ribosylation factor like GTPase 2; Belongs to the small GTPase superfamily. Arf family.	Uncharacterized protein.	0.454
ARL2	NRAS	ENSPPAP00000037929	ENSPPAP00000029807	ADP ribosylation factor like GTPase 2; Belongs to the small GTPase superfamily. Arf family.	NRAS proto-oncogene, GTPase.	0.401
ARL2	RHEB	ENSPPAP00000037929	ENSPPAP00000008640	ADP ribosylation factor like GTPase 2; Belongs to the small GTPase superfamily. Arf family.	Uncharacterized protein.	0.454
ARL3	RAB35	ENSPPAP00000023566	ENSPPAP00000008415	ADP ribosylation factor like GTPase 3; Belongs to the small GTPase superfamily. Arf family.	Uncharacterized protein.	0.402
ARL3	RAB8A	ENSPPAP00000023566	ENSPPAP00000035474	ADP ribosylation factor like GTPase 3; Belongs to the small GTPase superfamily. Arf family.	RAB8A, member RAS oncogene family.	0.450
DYNC1LI1	RAB4A	ENSPPAP00000026721	ENSPPAP00000027074	Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.	RAB4A, member RAS oncogene family.	0.559
ENSPPAP00000006260	ENSPPAP00000035001	ENSPPAP00000006260	ENSPPAP00000035001	Uncharacterized protein.	Uncharacterized protein.	0.565
ENSPPAP00000006260	RAP1A	ENSPPAP00000006260	ENSPPAP00000034589	Uncharacterized protein.	RAP1A, member of RAS oncogene family.	0.591
ENSPPAP00000006260	RRAGC	ENSPPAP00000006260	ENSPPAP00000013486	Uncharacterized protein.	Ras related GTP binding C.	0.424
ENSPPAP00000006260	RRAGD	ENSPPAP00000006260	ENSPPAP00000013270	Uncharacterized protein.	Ras related GTP binding D.	0.432
ENSPPAP00000010591	RALB	ENSPPAP00000010591	ENSPPAP00000025325	Uncharacterized protein.	RAS like proto-oncogene B.	0.533
ENSPPAP00000010638	HRAS	ENSPPAP00000010638	ENSPPAP00000010823	Uncharacterized protein.	HRas proto-oncogene, GTPase.	0.460
ENSPPAP00000010638	RAB8A	ENSPPAP00000010638	ENSPPAP00000035474	Uncharacterized protein.	RAB8A, member RAS oncogene family.	0.470
ENSPPAP00000010638	RALB	ENSPPAP00000010638	ENSPPAP00000025325	Uncharacterized protein.	RAS like proto-oncogene B.	0.567
ENSPPAP00000010638	RAP1A	ENSPPAP00000010638	ENSPPAP00000034589	Uncharacterized protein.	RAP1A, member of RAS oncogene family.	0.457