94 items (Pan paniscus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	MAPK14	Mitogen-activated protein kinase. (360 aa)
	SMIM24	Small integral membrane protein 24. (130 aa)
	ABCD4	ATP binding cassette subfamily D member 4. (606 aa)
	EHHADH	Enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase; Belongs to the enoyl-CoA hydratase/isomerase family. (723 aa)
	MLYCD	Malonyl-CoA decarboxylase. (491 aa)
	HADHB	Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta; Belongs to the thiolase-like superfamily. Thiolase family. (475 aa)
	PEX5	Peroxisomal biogenesis factor 5. (639 aa)
	ACAA1-2	Uncharacterized protein. (111 aa)
	ECI2	Enoyl-CoA delta isomerase 2. (434 aa)
	ADIPOR1	Adiponectin receptor 1. (375 aa)
	ACADVL	Acyl-CoA dehydrogenase very long chain. (677 aa)
	MCAT	Malonyl-CoA-acyl carrier protein transacylase. (390 aa)
	ABCD3	ATP binding cassette subfamily D member 3. (659 aa)
	BDH2	3-hydroxybutyrate dehydrogenase 2. (245 aa)
	ETFA	Electron transfer flavoprotein subunit alpha. (333 aa)
	ACAA2	Acetyl-CoA acyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. (397 aa)
	ACOXL	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (580 aa)
	ABCD1	ATP binding cassette subfamily D member 1. (745 aa)
	ENSPPAP00000031800	Uncharacterized protein. (352 aa)
	CYP24A1	Cytochrome P450 family 24 subfamily A member 1; Belongs to the cytochrome P450 family. (514 aa)
	ENSPPAP00000031480	Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family. (398 aa)
	ECI1	Enoyl-CoA delta isomerase 1; Belongs to the enoyl-CoA hydratase/isomerase family. (290 aa)
	ACAD11	Acyl-CoA dehydrogenase family member 11. (780 aa)
	PPARD	Peroxisome proliferator activated receptor delta. (441 aa)
	ENSPPAP00000030760	Uncharacterized protein. (667 aa)
	SLC25A17	Solute carrier family 25 member 17; Belongs to the mitochondrial carrier (TC 2.A.29) family. (306 aa)
	ENSPPAP00000030022	Uncharacterized protein. (100 aa)
	POR	NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5; In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (680 aa)
	CYP4F3	Cytochrome P450 family 4 subfamily F member 3; Belongs to the cytochrome P450 family. (520 aa)
	ETFB	Electron transfer flavoprotein subunit beta. (293 aa)
	SESN2	Sestrin 2. (480 aa)
	CPT1C	Carnitine palmitoyltransferase 1C; Belongs to the carnitine/choline acetyltransferase family. (745 aa)
	CPT2	Carnitine palmitoyltransferase 2; Belongs to the carnitine/choline acetyltransferase family. (658 aa)
	ECHDC1	Ethylmalonyl-CoA decarboxylase 1; Belongs to the enoyl-CoA hydratase/isomerase family. (303 aa)
	DECR1	2,4-dienoyl-CoA reductase 1. (335 aa)
	ALDH1L2	10-formyltetrahydrofolate dehydrogenase; In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily. (909 aa)
	ACOX1	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (660 aa)
	ACADM	Acyl-CoA dehydrogenase medium chain. (453 aa)
	PRKAA1	Non-specific serine/threonine protein kinase. (574 aa)
	ACADL	Acyl-CoA dehydrogenase long chain. (430 aa)
	DECR2	2,4-dienoyl-CoA reductase 2. (250 aa)
	LEP	Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa)
	ECHS1	Enoyl-CoA hydratase, short chain 1; Belongs to the enoyl-CoA hydratase/isomerase family. (290 aa)
	ENSPPAP00000024015	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (354 aa)
	ACAT1	Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. (427 aa)
	PPARGC1A	PPARG coactivator 1 alpha. (809 aa)
	ACOT8	Acyl-CoA thioesterase 8. (319 aa)
	LOC100973698	Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family. (712 aa)
	HADH	Uncharacterized protein. (452 aa)
	ADIPOR2	Adiponectin receptor 2. (386 aa)
	ETFDH	Electron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone. (619 aa)
	ECHDC2	Enoyl-CoA hydratase domain containing 2; Belongs to the enoyl-CoA hydratase/isomerase family. (292 aa)
	PEX2	Peroxisomal biogenesis factor 2. (305 aa)
	HSD17B10	Hydroxysteroid 17-beta dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (261 aa)
	ENSPPAP00000018575	Uncharacterized protein. (149 aa)
	ENSPPAP00000017735	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (457 aa)
	ILVBL	IlvB acetolactate synthase like; Belongs to the TPP enzyme family. (632 aa)
	ABCD2	ATP binding cassette subfamily D member 2. (740 aa)
	ACAD10	Acyl-CoA dehydrogenase family member 10. (1045 aa)
	PEX7	Peroxisomal biogenesis factor 7. (325 aa)
	ALOX15	Arachidonate 15-lipoxygenase. (662 aa)
	ENSPPAP00000012187	ADH_N domain-containing protein. (111 aa)
	ACOX2	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (681 aa)
	PPARG	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (505 aa)
	ALOX12	Arachidonate 12-lipoxygenase, 12S type. (663 aa)
	IVD	Isovaleryl-CoA dehydrogenase. (426 aa)
	ADH5	S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (383 aa)
	CROT	Carnitine O-octanoyltransferase; Belongs to the carnitine/choline acetyltransferase family. (612 aa)
	PEX13	Peroxisomal biogenesis factor 13. (403 aa)
	ECH1	Enoyl-CoA hydratase 1; Belongs to the enoyl-CoA hydratase/isomerase family. (328 aa)
	ADH7	Alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide. (317 aa)
	HAO2	Hydroxyacid oxidase 2. (351 aa)
	CYP4V2	Cytochrome P450 family 4 subfamily V member 2; Belongs to the cytochrome P450 family. (525 aa)
	GCDH	Glutaryl-CoA dehydrogenase. (438 aa)
	CPT1A	Carnitine palmitoyltransferase 1A; Belongs to the carnitine/choline acetyltransferase family. (773 aa)
	CYP4F2	Cytochrome P450 family 4 subfamily F member 2; Belongs to the cytochrome P450 family. (520 aa)
	CPT1B	Carnitine palmitoyltransferase 1B; Belongs to the carnitine/choline acetyltransferase family. (772 aa)
	ACADS	Acyl-CoA dehydrogenase short chain. (412 aa)
	HAO1	Hydroxyacid oxidase 1. (370 aa)
	CRAT	Carnitine O-acetyltransferase; Belongs to the carnitine/choline acetyltransferase family. (626 aa)
	ACOX3	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (700 aa)
	MTLN	Mitoregulin. (139 aa)
	HADHA	Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha; Belongs to the enoyl-CoA hydratase/isomerase family. (763 aa)
	ACAT2	Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. (397 aa)
	ADIPOQ	Adiponectin, C1Q and collagen domain containing. (286 aa)
	CYGB	GLOBIN domain-containing protein; Belongs to the globin family. (209 aa)
	ACAA1	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (299 aa)
	AMACR	Alpha-methylacyl-CoA racemase. (382 aa)
	SLC27A2	Solute carrier family 27 member 2. (620 aa)
	HACL1	2-hydroxyacyl-CoA lyase 1; Belongs to the TPP enzyme family. (578 aa)
	SCP2	Sterol carrier protein 2; Belongs to the thiolase-like superfamily. Thiolase family. (547 aa)
	ADH4	Alcohol dehydrogenase 4 (class II), pi polypeptide. (399 aa)
	PHYH	Phytanoyl-CoA 2-hydroxylase. (338 aa)
	HSD17B4	Hydroxysteroid 17-beta dehydrogenase 4. (761 aa)

Your Current Organism:

Pan paniscus

NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABCD1	ABCD2	ENSPPAP00000032174	ENSPPAP00000014896	ATP binding cassette subfamily D member 1.	ATP binding cassette subfamily D member 2.	0.918
ABCD1	ABCD3	ENSPPAP00000032174	ENSPPAP00000033942	ATP binding cassette subfamily D member 1.	ATP binding cassette subfamily D member 3.	0.959
ABCD1	ABCD4	ENSPPAP00000032174	ENSPPAP00000037208	ATP binding cassette subfamily D member 1.	ATP binding cassette subfamily D member 4.	0.627
ABCD1	ACOX1	ENSPPAP00000032174	ENSPPAP00000025791	ATP binding cassette subfamily D member 1.	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family.	0.540
ABCD1	ECH1	ENSPPAP00000032174	ENSPPAP00000008755	ATP binding cassette subfamily D member 1.	Enoyl-CoA hydratase 1; Belongs to the enoyl-CoA hydratase/isomerase family.	0.400
ABCD1	ECI2	ENSPPAP00000032174	ENSPPAP00000034957	ATP binding cassette subfamily D member 1.	Enoyl-CoA delta isomerase 2.	0.564
ABCD1	PEX13	ENSPPAP00000032174	ENSPPAP00000009936	ATP binding cassette subfamily D member 1.	Peroxisomal biogenesis factor 13.	0.751
ABCD1	PEX2	ENSPPAP00000032174	ENSPPAP00000019956	ATP binding cassette subfamily D member 1.	Peroxisomal biogenesis factor 2.	0.562
ABCD1	PEX5	ENSPPAP00000032174	ENSPPAP00000035867	ATP binding cassette subfamily D member 1.	Peroxisomal biogenesis factor 5.	0.487
ABCD1	PEX7	ENSPPAP00000032174	ENSPPAP00000013100	ATP binding cassette subfamily D member 1.	Peroxisomal biogenesis factor 7.	0.829
ABCD1	SCP2	ENSPPAP00000032174	ENSPPAP00000040187	ATP binding cassette subfamily D member 1.	Sterol carrier protein 2; Belongs to the thiolase-like superfamily. Thiolase family.	0.577
ABCD1	SLC25A17	ENSPPAP00000032174	ENSPPAP00000030339	ATP binding cassette subfamily D member 1.	Solute carrier family 25 member 17; Belongs to the mitochondrial carrier (TC 2.A.29) family.	0.676
ABCD1	SLC27A2	ENSPPAP00000032174	ENSPPAP00000040803	ATP binding cassette subfamily D member 1.	Solute carrier family 27 member 2.	0.709
ABCD2	ABCD1	ENSPPAP00000014896	ENSPPAP00000032174	ATP binding cassette subfamily D member 2.	ATP binding cassette subfamily D member 1.	0.918
ABCD2	ABCD3	ENSPPAP00000014896	ENSPPAP00000033942	ATP binding cassette subfamily D member 2.	ATP binding cassette subfamily D member 3.	0.927
ABCD2	ABCD4	ENSPPAP00000014896	ENSPPAP00000037208	ATP binding cassette subfamily D member 2.	ATP binding cassette subfamily D member 4.	0.627
ABCD2	ECH1	ENSPPAP00000014896	ENSPPAP00000008755	ATP binding cassette subfamily D member 2.	Enoyl-CoA hydratase 1; Belongs to the enoyl-CoA hydratase/isomerase family.	0.400
ABCD2	ECI2	ENSPPAP00000014896	ENSPPAP00000034957	ATP binding cassette subfamily D member 2.	Enoyl-CoA delta isomerase 2.	0.564
ABCD2	PEX13	ENSPPAP00000014896	ENSPPAP00000009936	ATP binding cassette subfamily D member 2.	Peroxisomal biogenesis factor 13.	0.701
ABCD2	PEX2	ENSPPAP00000014896	ENSPPAP00000019956	ATP binding cassette subfamily D member 2.	Peroxisomal biogenesis factor 2.	0.562